Cranial grafting of stem cell-derived microvesicles improves cognition and reduces neuropathology in the irradiated brain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 17, 2016, Pages 4836-4841

  Baulch, Janet E ^a   Acharya, Munjal M ^a   Allen, Barrett D ^a   Ru, Ning ^a   Chmielewski, Nicole N ^a   Martirosian, Vahan ^a   Giedzinski, Erich ^a   Syage, Amber ^a   Park, Audrey L ^a   Benke, Sarah N ^a   Parihar, Vipan K ^a   Limoli, Charles L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dendritic complexity; Human neural stem cells; Microvesicles; Neuroinflammation; Radiation induced cognitive dysfunction

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; BRAIN RADIATION; COGNITION; COGNITIVE DEFECT; CONFERENCE PAPER; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; HUMAN; HUMAN CELL; MEMBRANE MICROPARTICLE; MORPHOMETRICS; NERVOUS SYSTEM INFLAMMATION; NEURAL STEM CELL TRANSPLANTATION; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; RECOGNITION; SKULL IRRADIATION; ADVERSE EFFECTS; AMYGDALA; ANIMAL; BRAIN DAMAGE, CHRONIC; CELL CULTURE; COGNITION DISORDERS; HABITUATION; HIPPOCAMPUS; MALE; MICROGLIA; NEOCORTEX; NEURAL STEM CELL; NUDE RAT; PHYSIOLOGY; RADIATION INJURIES, EXPERIMENTAL; REPORTER GENE; TRANSPLANTATION; ULTRASTRUCTURE; XENOGRAFT;

AMYGDALA; ANIMALS; BRAIN DAMAGE, CHRONIC; CELL-DERIVED MICROPARTICLES; CELLS, CULTURED; COGNITION DISORDERS; CRANIAL IRRADIATION; GENES, REPORTER; HABITUATION, PSYCHOPHYSIOLOGIC; HETEROGRAFTS; HIPPOCAMPUS; HUMANS; MALE; MICROGLIA; NEOCORTEX; NEURAL STEM CELLS; RADIATION INJURIES, EXPERIMENTAL; RATS; RATS, NUDE;

EID: 84964778807     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1521668113     Document Type: Article

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