-
1
-
-
79955631888
-
Postoperative acute kidney injury is associated with hemoglobinemia and an enhanced oxidative stress response
-
1 Billings, FT IV, Ball, SK, Roberts, LJ II, Pretorius, M, Postoperative acute kidney injury is associated with hemoglobinemia and an enhanced oxidative stress response. Free Radic Biol Med 50:11 (2011), 1480–1487.
-
(2011)
Free Radic Biol Med
, vol.50
, Issue.11
, pp. 1480-1487
-
-
Billings, F.T.1
Ball, S.K.2
Roberts, L.J.3
Pretorius, M.4
-
2
-
-
7244243910
-
The radical and redox chemistry of myoglobin and hemoglobin: from in vitro studies to human pathology
-
2 Reeder, BJ, Svistunenko, DA, Cooper, CE, Wilson, MT, The radical and redox chemistry of myoglobin and hemoglobin: from in vitro studies to human pathology. Antioxid Redox Signal 6:6 (2004), 954–966.
-
(2004)
Antioxid Redox Signal
, vol.6
, Issue.6
, pp. 954-966
-
-
Reeder, B.J.1
Svistunenko, D.A.2
Cooper, C.E.3
Wilson, M.T.4
-
3
-
-
0036908599
-
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
-
3 Reiter, CD, Wang, X, Tanus-Santos, JE, et al. Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med 8:12 (2002), 1383–1389.
-
(2002)
Nat Med
, vol.8
, Issue.12
, pp. 1383-1389
-
-
Reiter, C.D.1
Wang, X.2
Tanus-Santos, J.E.3
-
4
-
-
74549121338
-
Hemodialysis-induced release of hemoglobin limits nitric oxide bioavailability and impairs vascular function
-
4 Meyer, C, Heiss, C, Drexhage, C, et al. Hemodialysis-induced release of hemoglobin limits nitric oxide bioavailability and impairs vascular function. J Am Coll Cardiol 55:5 (2010), 454–459.
-
(2010)
J Am Coll Cardiol
, vol.55
, Issue.5
, pp. 454-459
-
-
Meyer, C.1
Heiss, C.2
Drexhage, C.3
-
5
-
-
73949089031
-
Storage lesion in banked blood due to hemolysis-dependent disruption of nitric oxide homeostasis
-
5 Gladwin, MT, Kim-Shapiro, DB, Storage lesion in banked blood due to hemolysis-dependent disruption of nitric oxide homeostasis. Curr Opin Hematol 16:6 (2009), 515–523.
-
(2009)
Curr Opin Hematol
, vol.16
, Issue.6
, pp. 515-523
-
-
Gladwin, M.T.1
Kim-Shapiro, D.B.2
-
6
-
-
31044445795
-
Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin
-
6 Minneci, PC, Deans, KJ, Zhi, H, et al. Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin. J Clin Invest 115:12 (2005), 3409–3417.
-
(2005)
J Clin Invest
, vol.115
, Issue.12
, pp. 3409-3417
-
-
Minneci, P.C.1
Deans, K.J.2
Zhi, H.3
-
7
-
-
79961025290
-
Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion
-
7 Donadee, C, Raat, NJH, Kanias, T, et al. Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion. Circulation 124:4 (2011), 465–476.
-
(2011)
Circulation
, vol.124
, Issue.4
, pp. 465-476
-
-
Donadee, C.1
Raat, N.J.H.2
Kanias, T.3
-
8
-
-
84874930219
-
Association between cell-free hemoglobin, acetaminophen, and mortality in patients with sepsis: an observational study
-
8 Janz, DR, Bastarache, JA, Peterson, JF, et al. Association between cell-free hemoglobin, acetaminophen, and mortality in patients with sepsis: an observational study. Crit Care Med 41:3 (2013), 784–790.
-
(2013)
Crit Care Med
, vol.41
, Issue.3
, pp. 784-790
-
-
Janz, D.R.1
Bastarache, J.A.2
Peterson, J.F.3
-
9
-
-
56749163948
-
Pulmonary complications of sickle cell disease
-
9 Gladwin, MT, Vichinsky, E, Pulmonary complications of sickle cell disease. N Engl J Med 359:21 (2008), 2254–2265.
-
(2008)
N Engl J Med
, vol.359
, Issue.21
, pp. 2254-2265
-
-
Gladwin, M.T.1
Vichinsky, E.2
-
10
-
-
44249093233
-
Cell-free hemoglobin-based blood substitutes and risk of myocardial infarction and death: a meta-analysis
-
10 Natanson, C, Kern, SJ, Lurie, P, Banks, SM, Wolfe, SM, Cell-free hemoglobin-based blood substitutes and risk of myocardial infarction and death: a meta-analysis. JAMA 299:19 (2008), 2304–2312.
-
(2008)
JAMA
, vol.299
, Issue.19
, pp. 2304-2312
-
-
Natanson, C.1
Kern, S.J.2
Lurie, P.3
Banks, S.M.4
Wolfe, S.M.5
-
11
-
-
84859712543
-
Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy
-
11 Baek, JH, D'Agnillo, F, Vallelian, F, et al. Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy. J Clin Invest 122:4 (2012), 1444–1458.
-
(2012)
J Clin Invest
, vol.122
, Issue.4
, pp. 1444-1458
-
-
Baek, J.H.1
D'Agnillo, F.2
Vallelian, F.3
-
12
-
-
5344233478
-
Pulmonary arterial hypertension
-
12 Farber, HW, Loscalzo, J, Pulmonary arterial hypertension. N Engl J Med 351:16 (2004), 1655–1665.
-
(2004)
N Engl J Med
, vol.351
, Issue.16
, pp. 1655-1665
-
-
Farber, H.W.1
Loscalzo, J.2
-
13
-
-
84860285994
-
Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension
-
13 Archer, SL, Michelakis, ED, Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension. N Engl J Med 361:19 (2009), 1864–1871.
-
(2009)
N Engl J Med
, vol.361
, Issue.19
, pp. 1864-1871
-
-
Archer, S.L.1
Michelakis, E.D.2
-
14
-
-
84880721470
-
PATENT-1 Study Group. Riociguat for the treatment of pulmonary arterial hypertension
-
14 Ghofrani, H-A, Galiè, N, Grimminger, F, et al. PATENT-1 Study Group. Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med 369:4 (2013), 330–340.
-
(2013)
N Engl J Med
, vol.369
, Issue.4
, pp. 330-340
-
-
Ghofrani, H.-A.1
Galiè, N.2
Grimminger, F.3
-
15
-
-
34250870730
-
Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines
-
15 Badesch, DB, Abman, SH, Simonneau, G, Rubin, LJ, McLaughlin, VV, Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines. Chest 131:6 (2007), 1917–1928.
-
(2007)
Chest
, vol.131
, Issue.6
, pp. 1917-1928
-
-
Badesch, D.B.1
Abman, S.H.2
Simonneau, G.3
Rubin, L.J.4
McLaughlin, V.V.5
-
16
-
-
84865129051
-
Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism
-
16 Buehler, PW, Baek, JH, Lisk, C, et al. Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism. Am J Physiol Lung Cell Mol Physiol 303:4 (2012), L312–L326.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
, Issue.4
, pp. L312-L326
-
-
Buehler, P.W.1
Baek, J.H.2
Lisk, C.3
-
17
-
-
84886461087
-
Increased release of soluble CD163 by the peripheral blood mononuclear cells is associated with worse prognosis in patients with systemic sclerosis
-
17 Bielecki, M, Kowal, K, Lapinska, A, Chyczewski, L, Kowal-Bielecka, O, Increased release of soluble CD163 by the peripheral blood mononuclear cells is associated with worse prognosis in patients with systemic sclerosis. Adv Med Sci 58:1 (2013), 126–133.
-
(2013)
Adv Med Sci
, vol.58
, Issue.1
, pp. 126-133
-
-
Bielecki, M.1
Kowal, K.2
Lapinska, A.3
Chyczewski, L.4
Kowal-Bielecka, O.5
-
18
-
-
84867006894
-
Soluble CD163 in young sickle cell disease patients and their trait siblings: a biomarker for pulmonary hypertension and vaso-occlusive complications
-
18 Tantawy, AAG, Adly, AAM, Ismail, EAR, Soluble CD163 in young sickle cell disease patients and their trait siblings: a biomarker for pulmonary hypertension and vaso-occlusive complications. Blood Coagul Fibrinolysis 23:7 (2012), 640–648.
-
(2012)
Blood Coagul Fibrinolysis
, vol.23
, Issue.7
, pp. 640-648
-
-
Tantawy, A.A.G.1
Adly, A.A.M.2
Ismail, E.A.R.3
-
19
-
-
84987629683
-
-
Updated December 21, 2013.
-
19 National Institutes of Health Clinical Center. Vanderbilt University. Acetominophen for the reduction of oxidative injury in severe sepsis (ACROSS). NCT01739361. ClinicalTrials.gov. Bethesda, MD: National Library of Medicine. http://clinicaltrials.gov/show/NCT01739361, 2012 Updated December 21, 2013.
-
(2012)
-
-
-
20
-
-
84868273339
-
Longitudinal analysis casts doubt on the presence of genetic anticipation in heritable pulmonary arterial hypertension
-
20 Larkin, EK, Newman, JH, Austin, ED, et al. Longitudinal analysis casts doubt on the presence of genetic anticipation in heritable pulmonary arterial hypertension. Am J Respir Crit Care Med 186:9 (2012), 892–896.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, Issue.9
, pp. 892-896
-
-
Larkin, E.K.1
Newman, J.H.2
Austin, E.D.3
-
21
-
-
84890776626
-
Definitions and diagnosis of pulmonary hypertension
-
21 Hoeper, MM, Bogaard, HJ, Condliffe, R, et al. Definitions and diagnosis of pulmonary hypertension. J Am Coll Cardiol 62:suppl 25 (2013), D42–D50.
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. D42-D50
-
-
Hoeper, M.M.1
Bogaard, H.J.2
Condliffe, R.3
-
22
-
-
84865257955
-
Pulmonary hypertension due to left heart disease
-
22 Guazzi, M, Borlaug, BA, Pulmonary hypertension due to left heart disease. Circulation 126:8 (2012), 975–990.
-
(2012)
Circulation
, vol.126
, Issue.8
, pp. 975-990
-
-
Guazzi, M.1
Borlaug, B.A.2
-
23
-
-
84896116982
-
High prevalence of occult pulmonary venous hypertension revealed by fluid challenge in pulmonary hypertension
-
23 Robbins, IM, Hemnes, AR, Pugh, ME, et al. High prevalence of occult pulmonary venous hypertension revealed by fluid challenge in pulmonary hypertension. Circ Heart Fail 7:1 (2014), 116–122.
-
(2014)
Circ Heart Fail
, vol.7
, Issue.1
, pp. 116-122
-
-
Robbins, I.M.1
Hemnes, A.R.2
Pugh, M.E.3
-
24
-
-
20544448927
-
Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension
-
24 Sitbon, O, Humbert, M, Jaïs, X, et al. Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation 111:23 (2005), 3105–3111.
-
(2005)
Circulation
, vol.111
, Issue.23
, pp. 3105-3111
-
-
Sitbon, O.1
Humbert, M.2
Jaïs, X.3
-
25
-
-
77953313041
-
Pulmonary hypertension in hemolytic disorders: pulmonary vascular disease: the global perspective
-
25 Machado, RF, Gladwin, MT, Pulmonary hypertension in hemolytic disorders: pulmonary vascular disease: the global perspective. Chest 137:6_suppl (2010), 30S–38S.
-
(2010)
Chest
, vol.137
, Issue.6_suppl
, pp. 30S-38S
-
-
Machado, R.F.1
Gladwin, M.T.2
-
26
-
-
84878978503
-
Cell-free hemoglobin and its scavenger proteins: new disease models leading the way to targeted therapies
-
26 Schaer, DJ, Buehler, PW, Cell-free hemoglobin and its scavenger proteins: new disease models leading the way to targeted therapies. Cold Spring Harb Perspect Med, 3(6), 2013.
-
(2013)
Cold Spring Harb Perspect Med
, vol.3
, Issue.6
-
-
Schaer, D.J.1
Buehler, P.W.2
-
27
-
-
79957996593
-
Red cell distribution width outperforms other potential circulating biomarkers in predicting survival in idiopathic pulmonary arterial hypertension
-
27 Rhodes, CJ, Wharton, J, Howard, LS, Gibbs, JSR, Wilkins, MR, Red cell distribution width outperforms other potential circulating biomarkers in predicting survival in idiopathic pulmonary arterial hypertension. Heart 97:13 (2011), 1054–1060.
-
(2011)
Heart
, vol.97
, Issue.13
, pp. 1054-1060
-
-
Rhodes, C.J.1
Wharton, J.2
Howard, L.S.3
Gibbs, J.S.R.4
Wilkins, M.R.5
-
28
-
-
69449099102
-
Usefulness of red cell distribution width as a prognostic marker in pulmonary hypertension
-
28 Hampole, CV, Mehrotra, AK, Thenappan, T, Gomberg-Maitland, M, Shah, SJ, Usefulness of red cell distribution width as a prognostic marker in pulmonary hypertension. Am J Cardiol 104:6 (2009), 868–872.
-
(2009)
Am J Cardiol
, vol.104
, Issue.6
, pp. 868-872
-
-
Hampole, C.V.1
Mehrotra, A.K.2
Thenappan, T.3
Gomberg-Maitland, M.4
Shah, S.J.5
-
29
-
-
69249214138
-
Reduction in plasma haptoglobin in humans with acute pulmonary embolism causing tricuspid regurgitation
-
29 Kline, JA, Marchick, MR, Hogg, MM, Reduction in plasma haptoglobin in humans with acute pulmonary embolism causing tricuspid regurgitation. J Thromb Haemost 7:9 (2009), 1597–1599.
-
(2009)
J Thromb Haemost
, vol.7
, Issue.9
, pp. 1597-1599
-
-
Kline, J.A.1
Marchick, M.R.2
Hogg, M.M.3
-
30
-
-
74749103554
-
Rapid clearance of circulating haptoglobin from plasma during acute pulmonary embolism in rats results in HMOX1 up-regulation in peripheral blood leukocytes
-
30 Zagorski, J, Marchick, MR, Kline, JA, Rapid clearance of circulating haptoglobin from plasma during acute pulmonary embolism in rats results in HMOX1 up-regulation in peripheral blood leukocytes. J Thromb Haemost 8:2 (2010), 389–396.
-
(2010)
J Thromb Haemost
, vol.8
, Issue.2
, pp. 389-396
-
-
Zagorski, J.1
Marchick, M.R.2
Kline, J.A.3
-
31
-
-
79958005700
-
Iron deficiency is common in idiopathic pulmonary arterial hypertension
-
31 Ruiter, G, Lankhorst, S, Boonstra, A, et al. Iron deficiency is common in idiopathic pulmonary arterial hypertension. Eur Respir J 37:6 (2011), 1386–1391.
-
(2011)
Eur Respir J
, vol.37
, Issue.6
, pp. 1386-1391
-
-
Ruiter, G.1
Lankhorst, S.2
Boonstra, A.3
-
32
-
-
79960031695
-
Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights
-
32 Rhodes, CJ, Howard, LS, Busbridge, M, et al. Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights. J Am Coll Cardiol 58:3 (2011), 300–309.
-
(2011)
J Am Coll Cardiol
, vol.58
, Issue.3
, pp. 300-309
-
-
Rhodes, C.J.1
Howard, L.S.2
Busbridge, M.3
-
33
-
-
79953027647
-
Unexplained iron deficiency in idiopathic and heritable pulmonary arterial hypertension
-
33 Soon, E, Treacy, CM, Toshner, MR, et al. Unexplained iron deficiency in idiopathic and heritable pulmonary arterial hypertension. Thorax 66:4 (2011), 326–332.
-
(2011)
Thorax
, vol.66
, Issue.4
, pp. 326-332
-
-
Soon, E.1
Treacy, C.M.2
Toshner, M.R.3
-
34
-
-
80052225606
-
High levels of zinc-protoporphyrin identify iron metabolic abnormalities in pulmonary arterial hypertension
-
34 Decker, I, Ghosh, S, Comhair, SA, et al. High levels of zinc-protoporphyrin identify iron metabolic abnormalities in pulmonary arterial hypertension. Clin Transl Sci 4:4 (2011), 253–258.
-
(2011)
Clin Transl Sci
, vol.4
, Issue.4
, pp. 253-258
-
-
Decker, I.1
Ghosh, S.2
Comhair, S.A.3
-
35
-
-
47049113837
-
Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease
-
35 Ashley-Koch, AE, Elliott, L, Kail, ME, et al. Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease. Blood 111:12 (2008), 5721–5726.
-
(2008)
Blood
, vol.111
, Issue.12
, pp. 5721-5726
-
-
Ashley-Koch, A.E.1
Elliott, L.2
Kail, M.E.3
-
36
-
-
84887391095
-
Association between haptoglobin, hemopexin and mortality in adults with sepsis
-
36 Janz, DR, Bastarache, JA, Sills, G, et al. Association between haptoglobin, hemopexin and mortality in adults with sepsis. Crit Care, 17(6), 2013, R272.
-
(2013)
Crit Care
, vol.17
, Issue.6
, pp. R272
-
-
Janz, D.R.1
Bastarache, J.A.2
Sills, G.3
-
37
-
-
84864800812
-
Free hemoglobin concentration in severe sepsis: methods of measurement and prediction of outcome
-
37 Adamzik, M, Hamburger, T, Petrat, F, Peters, J, de Groot, H, Hartmann, M, Free hemoglobin concentration in severe sepsis: methods of measurement and prediction of outcome. Crit Care, 16(4), 2012, R125.
-
(2012)
Crit Care
, vol.16
, Issue.4
, pp. R125
-
-
Adamzik, M.1
Hamburger, T.2
Petrat, F.3
Peters, J.4
de Groot, H.5
Hartmann, M.6
|