Postoperative acute kidney injury is associated with hemoglobinemia and an enhanced oxidative stress response

Free Radical Biology and Medicine

Volumn 50, Issue 11, 2011, Pages 1480-1487

  Billings IV, Frederic T ^a   Ball, Stephen K ^a   Roberts II, L Jackson ^a   Pretorius, Mias ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Acute kidney injury; Cardiac surgery; Cardiopulmonary bypass; Free radicals; Hemeprotein; Isofurans; Isoprostanes; Neutrophil gelatinase associated lipocalin; Oxidative stress

Indexed keywords

ATORVASTATIN; BIOLOGICAL MARKER; CREATININE; HEMOGLOBIN; HEPARIN; ISOPROSTANE DERIVATIVE; LIPID; MYOGLOBIN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PLACEBO; PROTAMINE;

ACUTE KIDNEY FAILURE; AGED; ANTICOAGULANT THERAPY; ARTICLE; CARDIOPULMONARY BYPASS; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; FEMALE; HEMOGLOBIN BLOOD LEVEL; HUMAN; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; PATHOGENESIS; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; RANDOMIZED CONTROLLED TRIAL (TOPIC); URINE LEVEL;

ACUTE KIDNEY INJURY; AGED; CARDIOPULMONARY BYPASS; CASE-CONTROL STUDIES; F2-ISOPROSTANES; FEMALE; FURANS; HEMOGLOBINS; HEMOGLOBINURIA; HUMANS; LIPID PEROXIDATION; MALE; MIDDLE AGED; MYOGLOBIN; MYOGLOBINURIA; OXIDATIVE STRESS; POSTOPERATIVE COMPLICATIONS; PROGNOSIS;

EID: 79955631888     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.02.011     Document Type: Article

References (49)

1. K. Karkouti, D.N. Wijeysundera, T.M. Yau, J.L. Callum, D.C. Cheng, M. Crowther, J.-Y. Dupuis, S.E. Fremes, B. Kent, C. Laflamme, A. Lamy, J.-F. Legare, C.D. Mazer, S.A. McCluskey, F.D. Rubens, C. Sawchuk, and W.S. Beattie Acute kidney injury after cardiac surgery: focus on modifiable risk factors Circulation 119 2009 495 502
2. F. Billings, E. Siew, C. Yu, M. Pretorius, and N. Brown Early postoperative statin therapy is associated with a lower incidence of acute kidney injury following cardiac surgery J. Cardiothorac. Vasc. Anesth. 24 2010 913 920
3. M.H. Rosner, and M.D. Okusa Acute kidney injury associated with cardiac surgery Clin. J. Am. Soc. Nephrol. 1 2006 19 32
4. M. Haase, R. Bellomo, and A. Haase-Fielitz Novel biomarkers, oxidative stress, and the role of labile iron toxicity in cardiopulmonary bypass-associated acute kidney injury J. Am. Coll. Cardiol. 55 2010 2024 2033
5. M.J. Mack, A. Pfister, D. Bachand, R. Emery, M.J. Magee, M. Connolly, and V. Subramanian Comparison of coronary bypass surgery with and without cardiopulmonary bypass in patients with multivessel disease J. Thorac. Cardiovasc. Surg. 127 2004 167 173 (Pubitemid 38160480)
6. F. Scolari, R. Tardanico, R. Zani, A. Pola, B.F. Viola, E. Movilli, and R. Maiorca Cholesterol crystal embolism: a recognizable cause of renal disease Am. J. Kidney Dis. 36 2000 1089 1109
7. G. Zanardo, P. Michielon, A. Paccagnella, P. Rosi, M. Calo, V. Salandin, A. Da Ros, F. Michieletto, and G. Simini Acute renal failure in the patient undergoing cardiac operation: prevalence, mortality rate, and main risk factors J. Thorac. Cardiovasc. Surg. 107 1994 1489 1495 (Pubitemid 24184992)
8. J. Boldt, T. Brenner, A. Lehmann, S.W. Suttner, B. Kumle, and F. Isgro Is kidney function altered by the duration of cardiopulmonary bypass? Ann. Thorac. Surg. 75 2003 906 912 (Pubitemid 36298366)
9. U. Benedetto, E. Angeloni, R. Luciani, S. Refice, M. Stefanelli, C. Comito, A. Roscitano, and R. Sinatra Acute kidney injury after coronary artery bypass grafting: does rhabdomyolysis play a role? J. Thorac. Cardiovasc. Surg. 140 2010 464 470
10. C.C. Miller III, M.A. Villa, J. Sutton, D. Lau, K. Keyhani, A.L. Estrera, A. Azizzadeh, S.M. Coogan, and H.J. Safi Serum myoglobin and renal morbidity and mortality following thoracic and thoraco-abdominal aortic repair: does rhabdomyolysis play a role? Eur. J. Vasc. Endovasc. Surg. 37 2009 388 394
11. I.C. Vermeulen Windsant, M.G. Snoeijs, S.J. Hanssen, S. Altintas, J.H. Heijmans, T.A. Koeppel, G.W. Schurink, W.A. Buurman, and M.J. Jacobs Hemolysis is associated with acute kidney injury during major aortic surgery Kidney Int. 77 2010 913 920
12. L. Vercaemst Hemolysis in cardiac surgery patients undergoing cardiopulmonary bypass: a review in search of a treatment algorithm J. Extra Corpor. Technol. 40 2008 257 267
13. G. Inselmann, K. Kohler, V. Lange, R. Silber, and U. Nellessen Lipid peroxidation and cardiac troponin T release during routine cardiac surgery Cardiology 89 1998 124 129 (Pubitemid 28068603)
14. B.J. Reeder, D.A. Svistunenko, C.E. Cooper, and M.T. Wilson The radical and redox chemistry of myoglobin and hemoglobin: from in vitro studies to human pathology Antioxid. Redox Signaling 6 2004 954 966 (Pubitemid 39434932)
15. K.P. Moore, S.G. Holt, R.P. Patel, D.A. Svistunenko, W. Zackert, D. Goodier, B.J. Reeder, M. Clozel, R. Anand, C.E. Cooper, J.D. Morrow, M.T. Wilson, V. Darley-Usmar, and L.J. Roberts II A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure J. Biol. Chem. 273 1998 31731 31737 (Pubitemid 29177103)
16. S. Holt, B. Reeder, M. Wilson, S. Harvey, J.D. Morrow, L.J. Roberts II, and K. Moore Increased lipid peroxidation in patients with rhabdomyolysis Lancet 353 1999 1241 (Pubitemid 29168466)
17. S. Christen, B. Finckh, J. Lykkesfeldt, P. Gessler, M. Frese-Schaper, P. Nielsen, E.R. Schmid, and B. Schmitt Oxidative stress precedes peak systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation Free Radic. Biol. Med. 38 2005 1323 1332 (Pubitemid 40602834)
18. 4 poisoning? Free Radic. Biol. Med. 38 2005 698 710 (Pubitemid 40249740)
19. J.P. Fessel, N.A. Porter, K.P. Moore, J.R. Sheller, and L.J. Roberts II Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension Proc. Natl Acad. Sci. USA 99 2002 16713 16718 (Pubitemid 36034038)
20. O. Boutaud, K.P. Moore, B.J. Reeder, D. Harry, A.J. Howie, S. Wang, C.K. Carney, T.S. Masterson, T. Amin, D.W. Wright, M.T. Wilson, J.A. Oates, and L.J. Roberts II Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure Proc. Natl Acad. Sci. USA 107 2010 2699 2704
21. C.L. Lin, Y.T. Hsu, T.K. Lin, J.D. Morrow, J.C. Hsu, Y.H. Hsu, T.C. Hsieh, P.K. Tsay, and H.C. Yen Increased levels of F2-isoprostanes following aneurysmal subarachnoid hemorrhage in humans Free Radic. Biol. Med. 40 2006 1466 1473
22. E.S. Klings, B.W. Christman, J. McClung, A.F. Stucchi, L. McMahon, M. Brauer, and H.W. Farber Increased F2 isoprostanes in the acute chest syndrome of sickle cell disease as a marker of oxidative stress Am. J. Respir. Crit. Care Med. 164 2001 1248 1252 (Pubitemid 33052259)
23. R.L. Mehta, J.A. Kellum, S.V. Shah, B.A. Molitoris, C. Ronco, D.G. Warnock, and A. Levin Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury Crit. Care 11 2007 R31
24. E. Macedo, R. Malhotra, R. Claure-Del Granado, P. Fedullo, and R.L. Mehta Defining urine output criterion for acute kidney injury in critically ill patients Nephrol. Dial. Transplant. 26 2010 509 515
25. H. Palomba, I. de Castro, A.L. Neto, S. Lage, and L. Yu Acute kidney injury prediction following elective cardiac surgery: AKICS Score Kidney Int. 72 2007 624 631 (Pubitemid 47312800)
26. A.S. Levey, J. Coresh, T. Greene, L.A. Stevens, Y.L. Zhang, S. Hendriksen, J.W. Kusek, and F. Van Lente Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate Ann. Intern. Med. 145 2006 247 254 (Pubitemid 46768608)
27. J. Unger, G. Filippi, and W. Patsch Measurements of free hemoglobin and hemolysis index: EDTA- or lithium-heparinate plasma? Clin. Chem. 53 2007 1717 1718 (Pubitemid 47340074)
28. G.L. Milne, S.C. Sanchez, E.S. Musiek, and J.D. Morrow Quantification of F2-isoprostanes as a biomarker of oxidative stress Nat. Protoc. 2 2007 221 226 (Pubitemid 47040087)
29. R. De Caterina, F. Cipollone, F.P. Filardo, M. Zimarino, W. Bernini, G. Lazzerini, T. Bucciarelli, A. Falco, P. Marchesani, R. Muraro, A. Mezzetti, and G. Ciabattoni Low-density lipoprotein level reduction by the 3-hydroxy-3-methylglutaryl coenzyme-A inhibitor simvastatin is accompanied by a related reduction of F2-isoprostane formation in hypercholesterolemic subjects: no further effect of vitamin E Circulation 106 2002 2543 2549 (Pubitemid 35340689)
30. J.D. Morrow, B. Frei, A.W. Longmire, J.M. Gaziano, S.M. Lynch, Y. Shyr, W.E. Strauss, J.A. Oates, and L.J. Roberts II Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers: smoking as a cause of oxidative damage N. Engl. J. Med. 332 1995 1198 1203
31. A. Miceli, R. Capoun, C. Fino, P. Narayan, A.J. Bryan, G.D. Angelini, and M. Caputo Effects of angiotensin-converting enzyme inhibitor therapy on clinical outcome in patients undergoing coronary artery bypass grafting J. Am. Coll. Cardiol. 54 2009 1178 1184
32. A.T. Ulus, A. Aksoyek, M. Ozkan, S.F. Katircioglu, and S. Basu Cardiopulmonary bypass as a cause of free radical-induced oxidative stress and enhanced blood-borne isoprostanes in humans Free Radic. Biol. Med. 34 2003 911 917 (Pubitemid 36316075)
33. L.J. Roberts II, and J.P. Fessel The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation Chem. Phys. Lipids 128 2004 173 186 (Pubitemid 38167386)
34. S. Meng, L.J. Roberts II, G.W. Cason, T.S. Curry, and R.D. Manning Jr. Superoxide dismutase and oxidative stress in Dahl salt-sensitive and -resistant rats Am. J. Physiol. Regul. Integr. Comp. Physiol. 283 2002 R732 738
35. K.A. Nath, J.P. Grande, A.J. Croatt, S. Likely, R.P. Hebbel, and H. Enright Intracellular targets in heme protein-induced renal injury Kidney Int. 53 1998 100 111 (Pubitemid 28066908)
36. M. Legrand, E.G. Mik, T. Johannes, D. Payen, and C. Ince Renal hypoxia and dysoxia after reperfusion of the ischemic kidney Mol. Med. 14 2008 502 516
37. E.Y. Plotnikov, A.A. Chupyrkina, I.B. Pevzner, N.K. Isaev, and D.B. Zorov Myoglobin causes oxidative stress, increase of NO production and dysfunction of kidney's mitochondria Biochim. Biophys. Acta 1792 2009 796 803
38. M.S. Paller Hemoglobin- and myoglobin-induced acute renal failure in rats: role of iron in nephrotoxicity Am. J. Physiol. Renal Physiol. 255 1988 F539 F544
39. J.L. Koyner, R. Sher Ali, and P.T. Murray Antioxidants: do they have a place in the prevention or therapy of acute kidney injury? Nephron Exp. Nephrol. 109 2008 e109 117
40. L.J. Roberts II, J.A. Oates, M.F. Linton, S. Fazio, B.P. Meador, M.D. Gross, Y. Shyr, and J.D. Morrow The relationship between dose of vitamin E and suppression of oxidative stress in humans Free Radic. Biol. Med. 43 2007 1388 1393 (Pubitemid 47532362)
41. G.J. Kato Haptoglobin, halts hemoglobins havoc J. Clin. Invest. 119 2009 2140 2142
42. I.S. Morgan, M. Codispoti, K. Sanger, and P.S. Mankad Superiority of centrifugal pump over roller pump in paediatric cardiac surgery: prospective randomised trial Eur. J. Cardiothorac. Surg. 13 1998 526 532 (Pubitemid 28273343)
43. K. Tanaka, Y. Kanamori, T. Sato, C. Kondo, Y. Katayama, I. Yada, H. Yuasa, and M. Kusagawa Administration of haptoglobin during cardiopulmonary bypass surgery ASAIO Trans. 37 1991 M482 483
44. K.M. Schmidt-Ott, K. Mori, A. Kalandadze, J.Y. Li, N. Paragas, T. Nicholas, P. Devarajan, and J. Barasch Neutrophil gelatinase-associated lipocalin-mediated iron traffic in kidney epithelia Curr. Opin. Nephrol. Hypertens. 15 2006 442 449 (Pubitemid 44297988)
45. J. Mishra, C. Dent, R. Tarabishi, M.M. Mitsnefes, Q. Ma, C. Kelly, S.M. Ruff, K. Zahedi, M. Shao, J. Bean, K. Mori, J. Barasch, and P. Devarajan Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery Lancet 365 2005 1231 1238 (Pubitemid 40469655)
46. T.E. Perry, J.D. Muehlschlegel, K.Y. Liu, A.A. Fox, C.D. Collard, S.K. Shernan, and S.C. Body Plasma neutrophil gelatinase-associated lipocalin and acute postoperative kidney injury in adult cardiac surgical patients Anesth. Analg. 110 2010 1541 1547
47. U. Benedetto, S. Sciarretta, A. Roscitano, B. Fiorani, S. Refice, E. Angeloni, and R. Sinatra Preoperative angiotensin-converting enzyme inhibitors and acute kidney injury after coronary artery bypass grafting Ann. Thorac. Surg. 86 2008 1160 1165
48. M. Pretorius, J.A. McFarlane, D.E. Vaughan, N.J. Brown, and L.J. Murphey Angiotensin-converting enzyme inhibition and smoking potentiate the kinin response to cardiopulmonary bypass Clin. Pharmacol. Ther. 76 2004 379 387 (Pubitemid 39313129)
49. W.C. Chiang, C.T. Chien, W.W. Lin, S.L. Lin, Y.M. Chen, C.F. Lai, K.D. Wu, J. Chao, and T.J. Tsai Early activation of bradykinin B2 receptor aggravates reactive oxygen species generation and renal damage in ischemia/reperfusion injury Free Radic. Biol. Med. 41 2006 1304 1314 (Pubitemid 44466325)