Krüppel-like factor 9 promotes hepatic cytochrome P450 2D6 expression during pregnancy in CYP2D6-humanized mice

Molecular Pharmacology

Volumn 86, Issue 6, 2014, Pages 727-735

  Koh, Kwi Hye ^a   Pan, Xian ^a   Zhang, Wei ^b   McLachlan, Alan ^b   Urrutia, Raul ^c   Jeong, Hyunyoung ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

^c MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; ACTIVATING TRANSCRIPTION FACTOR 5; CYTOCHROME P450 2D6; EARLY GROWTH RESPONSE FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 3GAMMA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 10; KRUPPEL LIKE FACTOR 9; NUCLEAR RECEPTOR NR1D1; TRANSCRIPTION FACTOR JUNB; UNCLASSIFIED DRUG; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, MOUSE; KLF9 PROTEIN, HUMAN; KLF9 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME INDUCTION; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION; UPREGULATION; ANIMAL; BREEDING; CHEMISTRY; ENZYMOLOGY; GENETICS; HEK293 CELL LINE; LIVER; MALE; METABOLISM; PHYSIOLOGY;

ANIMALS; CYTOCHROME P-450 CYP2D6; FEMALE; HEK293 CELLS; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LIVER; MALE; MICE; PREGNANCY; PREGNANCY, ANIMAL; PROMOTER REGIONS, GENETIC;

EID: 84964698054     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.114.093666     Document Type: Article

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