Novel polymorphisms of nuclear receptor SHP associated with functional and structural changes

Journal of Biological Chemistry

Volumn 285, Issue 32, 2010, Pages 24871-24881

  Zhou, Taofeng ^a,b   Zhang, Yuxia ^a   Macchiarulo, Antonio ^c   Yang, Zhihong ^a   Cellanetti, Marco ^c   Coto, Eliecer ^d   Xu, Pingyi ^b   Pellicciari, Roberto ^c   Wang, Li ^a  

^a UNIVERSITY OF UTAH   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF PERUGIA   (Italy)

^d HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; MOLECULAR DYNAMICS; PROTEINS;

AUTOSOMAL DOMINANTS; GENETIC VARIATION; HETERODIMERS; HUMAN SUBJECTS; LEUKOENCEPHALOPATHY; MOLECULAR DYNAMICS SIMULATIONS; NORMAL FUNCTION; NUCLEAR RECEPTORS; NUCLEAR TRANSLOCATIONS; PROTEIN EXPRESSIONS; PROTEIN STABILITY; SINGLE NUCLEOTIDE POLYMORPHISMS; STRUCTURAL CHANGE; STRUCTURAL ELEMENTS; UBIQUITINATION; UNTRANSLATED REGIONS;

POLYMORPHISM;

ALANINE; APOLIPOPROTEIN C3; ARGININE; ASPARAGINE; CELL NUCLEUS RECEPTOR; CYTOSINE; ESTROGEN RELATED RECEPTOR ALPHA; GLYCINE; GUANINE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; HISTIDINE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 3; LIVER RECEPTOR HOMOLOG 1; LYSINE; MESSENGER RNA; MUTANT PROTEIN; NUCLEAR RECEPTOR SHP; THYMINE; UNCLASSIFIED DRUG; DNA; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE SHP 1; UBIQUITIN;

3' UNTRANSLATED REGION; ACETYLATION; ARTICLE; CADASIL; CELL NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; EXON; GENETIC VARIABILITY; HETEROZYGOTE; HUMAN; HUMAN CELL; INTRON; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SINGLE NUCLEOTIDE POLYMORPHISM; UBIQUITINATION; BIOLOGICAL MODEL; CASE CONTROL STUDY; CHEMISTRY; COMPUTER SIMULATION; GENETIC POLYMORPHISM; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY;

CASE-CONTROL STUDIES; COMPUTER SIMULATION; DNA; DNA MUTATIONAL ANALYSIS; HETEROZYGOTE; HUMANS; INTRONS; MODELS, GENETIC; MUTATION; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RNA, MESSENGER; UBIQUITIN;

EID: 77955302379     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.133280     Document Type: Article

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