Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology

Journal of Biological Chemistry

Volumn 287, Issue 10, 2012, Pages 7010-7025

  Daftary, Gaurang S ^a   Lomberk, Gwen A ^a   Buttar, Navtej S ^a   Allen, Thomas W ^a   Grzenda, Adrienne ^a   Zhang, Jinsan ^a   Zheng, Ye ^a   Mathison, Angela J ^a   Gada, Ravi P ^a   Calvo, Ezequiel ^b   Iovanna, Juan L ^c   Billadeau, Daniel D ^a   Prendergast, Franklyn G ^a   Urrutia, Raul ^a  

^a MAYO CLINIC   (United States)

^b LAVAL UNIVERSITY   (Canada)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION DOMAIN; ATOMIC RESOLUTION; BIOCHEMICAL CHARACTERIZATION; BIOCHEMICAL MECHANISMS; COFACTORS; ENDOCRINE DISEASE; FUNCTIONAL INFORMATION; GENE SILENCING; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASES; IN-VIVO; ISOFORMS; NUCLEAR TRANSLOCATIONS; REPRODUCTIVE BIOLOGY; SUBCELLULAR LOCALIZATIONS; TYROSINE KINASE;

AMINO ACIDS; BINDING SITES; CHROMOSOMES; COMPUTER SIMULATION; GENETIC ENGINEERING; METABOLISM; PHOSPHORYLATION; TRANSCRIPTION FACTORS;

GENE EXPRESSION REGULATION;

KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 16; KRUPPEL LIKE FACTOR 3; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SIN3A; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CELLULAR DISTRIBUTION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SUBSTITUTION; CHROMATIN; FEEDER CELLS; FEMALE; GENE SILENCING; GONADAL STEROID HORMONES; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MUTATION, MISSENSE; NUCLEAR LOCALIZATION SIGNALS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; REPRODUCTION; RESPONSE ELEMENTS; SIN3 HISTONE DEACETYLASE AND COREPRESSOR COMPLEX; STRUCTURE-ACTIVITY RELATIONSHIP; UTERUS;

EID: 84863280739     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.266007     Document Type: Article

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