-
1
-
-
84964601318
-
Precision medicine for advanced pancreas cancer: the Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) trial
-
Chantrill LA, Nagrial AM, Watson C et al. Precision medicine for advanced pancreas cancer: the Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) trial. Clin Cancer Res 2015; 354: 1698-1705.
-
(2015)
Clin Cancer Res
, vol.354
, pp. 1698-1705
-
-
Chantrill, L.A.1
Nagrial, A.M.2
Watson, C.3
-
2
-
-
84884176329
-
Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients
-
Taly V, Pekin D, Benhaim L et al. Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients. Clin Chem 2013; 59: 1722-1731.
-
(2013)
Clin Chem
, vol.59
, pp. 1722-1731
-
-
Taly, V.1
Pekin, D.2
Benhaim, L.3
-
3
-
-
84949009842
-
Analytical and clinical validation of a digital sequencing panel for quantitative, highly accurate evaluation of cell-free circulating tumor DNA
-
Lanman RB, Mortimer SA, Zill OA et al. Analytical and clinical validation of a digital sequencing panel for quantitative, highly accurate evaluation of cell-free circulating tumor DNA. PLoS One 2015; 10: e0140712.
-
(2015)
PLoS One
, vol.10
-
-
Lanman, R.B.1
Mortimer, S.A.2
Zill, O.A.3
-
4
-
-
84943303014
-
Cell-free DNA next-generation sequencing in pancreatobiliary carcinomas
-
Zill OA, Greene C, Sebisanovic D et al. Cell-free DNA next-generation sequencing in pancreatobiliary carcinomas. Cancer Discov 2015; 5: 1040-1048.
-
(2015)
Cancer Discov
, vol.5
, pp. 1040-1048
-
-
Zill, O.A.1
Greene, C.2
Sebisanovic, D.3
-
5
-
-
84872020299
-
Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing
-
Chan KC, Jiang P, Zheng YW et al. Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing. Clin Chem 2013; 59: 211-224.
-
(2013)
Clin Chem
, vol.59
, pp. 211-224
-
-
Chan, K.C.1
Jiang, P.2
Zheng, Y.W.3
-
6
-
-
84877579861
-
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
-
Murtaza M, Dawson SJ, Tsui DW et al. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature 2013; 497: 108-112.
-
(2013)
Nature
, vol.497
, pp. 108-112
-
-
Murtaza, M.1
Dawson, S.J.2
Tsui, D.W.3
-
7
-
-
84943328606
-
Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease
-
Butler TM, Johnson-Camacho K, Peto M et al. Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease. PLoS One 2015; 10: e0136407.
-
(2015)
PLoS One
, vol.10
-
-
Butler, T.M.1
Johnson-Camacho, K.2
Peto, M.3
-
8
-
-
80052436485
-
High fragmentation characterizes tumour-derived circulating DNA
-
Mouliere F, Robert B, Arnau Peyrotte E et al. High fragmentation characterizes tumour-derived circulating DNA. PLoS One 2011; 6: e23418.
-
(2011)
PLoS One
, vol.6
-
-
Mouliere, F.1
Robert, B.2
Arnau Peyrotte, E.3
-
9
-
-
33749557625
-
Biology of circulating mRNA: still more questions than answers?
-
Fleischhacker M. Biology of circulating mRNA: still more questions than answers? Ann N Y Acad Sci 2006; 1075: 40-49.
-
(2006)
Ann N Y Acad Sci
, vol.1075
, pp. 40-49
-
-
Fleischhacker, M.1
-
10
-
-
48749122914
-
Circulating microRNAs as stable bloodbased markers for cancer detection
-
Mitchell PS, Parkin RK, Kroh EM et al. Circulating microRNAs as stable bloodbased markers for cancer detection. Proc Natl Acad Sci USA 2008; 105: 10513-10518.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 10513-10518
-
-
Mitchell, P.S.1
Parkin, R.K.2
Kroh, E.M.3
-
11
-
-
1542328938
-
Characterization of amplifiable, circulating RNA in plasma and its potential as a tool for cancer diagnostics
-
El-Hefnawy T, Raja S, Kelly L et al. Characterization of amplifiable, circulating RNA in plasma and its potential as a tool for cancer diagnostics. Clin Chem 2004; 50: 564-573.
-
(2004)
Clin Chem
, vol.50
, pp. 564-573
-
-
El-Hefnawy, T.1
Raja, S.2
Kelly, L.3
-
13
-
-
57049103401
-
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
-
Skog J, Wurdinger T, van Rijn S et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol 2008; 10: 1470-1476.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1470-1476
-
-
Skog, J.1
Wurdinger, T.2
van Rijn, S.3
-
14
-
-
84879603171
-
Exosomes in tumor microenvironment influence cancer progression and metastasis
-
Kahlert C, Kalluri R. Exosomes in tumor microenvironment influence cancer progression and metastasis. J Mol Med (Berl) 2013; 91: 431-437.
-
(2013)
J Mol Med (Berl)
, vol.91
, pp. 431-437
-
-
Kahlert, C.1
Kalluri, R.2
-
15
-
-
84894189683
-
Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer
-
Kahlert C, Melo SA, Protopopov A et al. Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer. J Biol Chem 2014; 289: 3869-3875.
-
(2014)
J Biol Chem
, vol.289
, pp. 3869-3875
-
-
Kahlert, C.1
Melo, S.A.2
Protopopov, A.3
-
16
-
-
84901842265
-
Double-stranded DNA in exosomes: a novel biomarker in cancer detection
-
Thakur BK, Zhang H, Becker A et al. Double-stranded DNA in exosomes: a novel biomarker in cancer detection. Cell Res 2014; 24: 766-769.
-
(2014)
Cell Res
, vol.24
, pp. 766-769
-
-
Thakur, B.K.1
Zhang, H.2
Becker, A.3
-
17
-
-
84946040120
-
COSMIC: exploring the world's knowledge of somatic mutations in human cancer
-
Forbes SA, Beare D, Gunasekaran P et al. COSMIC: exploring the world's knowledge of somatic mutations in human cancer. Nucleic Acids Res 2015; 43: D805-D811.
-
(2015)
Nucleic Acids Res
, vol.43
, pp. D805-D811
-
-
Forbes, S.A.1
Beare, D.2
Gunasekaran, P.3
-
18
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov LB, Nik-Zainal S, Wedge DC et al. Signatures of mutational processes in human cancer. Nature 2013; 500: 415-421.
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
-
19
-
-
84929001104
-
The genotype-tissue expression (GTEx) pilot analysis: multitissue gene regulation in humans
-
Consortium G. The genotype-tissue expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science 2015; 348: 648-660.
-
(2015)
Science
, vol.348
, pp. 648-660
-
-
Consortium, G.1
-
20
-
-
84991030590
-
Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors
-
Overwijk WW, Wang E, Marincola FM et al. Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors. J Immunother Cancer 2013; 1: 11.
-
(2013)
J Immunother Cancer
, vol.1
, pp. 11
-
-
Overwijk, W.W.1
Wang, E.2
Marincola, F.M.3
-
21
-
-
84928770388
-
Neoantigens in cancer immunotherapy
-
Schumacher TN, Schreiber RD. Neoantigens in cancer immunotherapy. Science 2015; 348: 69-74.
-
(2015)
Science
, vol.348
, pp. 69-74
-
-
Schumacher, T.N.1
Schreiber, R.D.2
-
22
-
-
84924056345
-
Whole genomes redefine the mutational landscape of pancreatic cancer
-
Waddell N, Pajic M, Patch AM et al. Whole genomes redefine the mutational landscape of pancreatic cancer. Nature 2015; 518: 495-501.
-
(2015)
Nature
, vol.518
, pp. 495-501
-
-
Waddell, N.1
Pajic, M.2
Patch, A.M.3
-
23
-
-
80052571282
-
Effect of the overexpression of BRCA2 unclassified missense variants on spontaneous homologous recombination in human cells
-
Balia C, Galli A, Caligo MA. Effect of the overexpression of BRCA2 unclassified missense variants on spontaneous homologous recombination in human cells. Breast Cancer Res Treat 2011; 129: 1001-1009.
-
(2011)
Breast Cancer Res Treat
, vol.129
, pp. 1001-1009
-
-
Balia, C.1
Galli, A.2
Caligo, M.A.3
-
24
-
-
80054820265
-
An emerging entity: pancreatic adenocarcinoma associated with a known BRCA mutation: clinical descriptors, treatment implications, and future directions
-
Lowery MA, Kelsen DP, Stadler ZK et al. An emerging entity: pancreatic adenocarcinoma associated with a known BRCA mutation: clinical descriptors, treatment implications, and future directions. Oncologist 2011; 16: 1397-1402.
-
(2011)
Oncologist
, vol.16
, pp. 1397-1402
-
-
Lowery, M.A.1
Kelsen, D.P.2
Stadler, Z.K.3
-
25
-
-
84868273967
-
Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2- targeting drugs
-
Henjes F, Bender C, von der Heyde S et al. Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2- targeting drugs. Oncogenesis 2012; 1: e16.
-
(2012)
Oncogenesis
, vol.1
-
-
Henjes, F.1
Bender, C.2
von der Heyde, S.3
-
26
-
-
84900301377
-
Cancer immunotherapy based on mutationspecific CD4+ T cells in a patient with epithelial cancer
-
Tran E, Turcotte S, Gros A et al. Cancer immunotherapy based on mutationspecific CD4+ T cells in a patient with epithelial cancer. Science 2014; 344: 641-645.
-
(2014)
Science
, vol.344
, pp. 641-645
-
-
Tran, E.1
Turcotte, S.2
Gros, A.3
-
27
-
-
84895876130
-
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
-
Gerlinger M, Horswell S, Larkin J et al. Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing. Nat Genet 2014; 46: 225-233.
-
(2014)
Nat Genet
, vol.46
, pp. 225-233
-
-
Gerlinger, M.1
Horswell, S.2
Larkin, J.3
|