Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Na v 1.7

Pain

Volumn 156, Issue 9, 2015, Pages 1637-1646

  Namer, Barbara ^a   Ørstavik, Kristin ^b   Schmidt, Roland ^c   Kleggetveit, Inge Petter ^b   Weidner, Christian ^a   Mørk, Cato ^d   Kvernebo, Mari Skylstad ^e   Kvernebo, Knut ^e   Salter, Hugh ^f   Carr, Thomas Hedley ^g   Segerdahl, Märta ^f   Quiding, Hans ^f   Waxman, Stephen George ^h   Handwerker, Hermann Otto ^a   Torebjörk, Hans Erik ^c   Jørum, Ellen ^b   Schmelz, Martin ⁱ  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UPPSALA UNIVERSITY   (Sweden)

^d NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^e OSLO UNIVERSITY HOSPITAL   (Norway)

^f KAROLINSKA INSTITUTE   (Sweden)

^g ASTRAZENECA   (United Kingdom)

^h YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Electrophysiology; Microneurography; Nociceptor; Peripheral nerve; Sodium channel

Indexed keywords

SODIUM CHANNEL NAV1.7; SODIUM CHANNEL NAV1.8; ISOLEUCINE; SCN9A PROTEIN, HUMAN; THREONINE;

ARTICLE; AXON; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROMELALGIA; GAIN OF FUNCTION MUTATION; HEAT SENSITIVITY; HUMAN; LATENT PERIOD; MICRONEUROGRAPHY; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CONDUCTION VELOCITY; NERVE FIBER; NERVE POTENTIAL; NEUROGRAPHY; NONMYELINATED NERVE; PAIN RECEPTOR; PAIN THRESHOLD; PERONEUS NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORY NERVE CELL; SYMPATHETIC NERVE CELL; CASE CONTROL STUDY; CONVALESCENCE; ELECTROPHYSIOLOGY; FEMALE; GENETICS; MALE; MUTATION; NERVE CONDUCTION; NEUROLOGIC EXAMINATION; PATCH CLAMP TECHNIQUE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REACTION TIME; STIMULATION;

CASE-CONTROL STUDIES; ELECTROPHYSIOLOGY; ERYTHROMELALGIA; FEMALE; HUMANS; ISOLEUCINE; MALE; MUTATION; NAV1.7 VOLTAGE-GATED SODIUM CHANNEL; NERVE FIBERS, UNMYELINATED; NEURAL CONDUCTION; NEUROLOGIC EXAMINATION; NOCICEPTORS; PAIN THRESHOLD; PATCH-CLAMP TECHNIQUES; PERONEAL NERVE; PHYSICAL STIMULATION; REACTION TIME; RECOVERY OF FUNCTION; THREONINE;

EID: 84964678902     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1097/j.pain.0000000000000229     Document Type: Article

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