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Volumn 8, Issue MAR, 2016, Pages

Astrocytes as the main players in primary degenerative disorders of the human central nervous system

Author keywords

Astrocytes; Human central nervous system; Neurodegeneration; Primary astrocytic degeneration; Primary degenerative disorders

Indexed keywords

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ASTROCYTE; BEHAVIOR; CENTRAL NERVOUS SYSTEM; DEGENERATIVE DISEASE; FRONTOTEMPORAL DEMENTIA; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; MAJOR DEPRESSION; MOUSE; NERVE CELL; NERVE DEGENERATION; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; SCHIZOPHRENIA; SHORT SURVEY; SPINOCEREBELLAR DEGENERATION;

EID: 84964670013     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2016.00045     Document Type: Short Survey
Times cited : (29)

References (51)
  • 1
    • 84858445314 scopus 로고    scopus 로고
    • Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine
    • Alexander, K. S., Wu, H. Q., and Bruno, J. P. (2012). Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine. Psychopharmac 220, 627-637. doi: 10.1007/s00213-011-2539-2.
    • (2012) Psychopharmac , vol.220 , pp. 627-637
    • Alexander, K.S.1    Wu, H.Q.2    Bruno, J.P.3
  • 2
    • 0035958752 scopus 로고    scopus 로고
    • Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: upregulation in reactive astrocytes
    • Aronica, E., Catania, M. V., Geurts, J., Yankaya, B., and Troost, D. (2001). Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: upregulation in reactive astrocytes. Neuroscience 105, 509-520. doi: 10.1016/S0306-4522(01)00181-6.
    • (2001) Neuroscience , vol.105 , pp. 509-520
    • Aronica, E.1    Catania, M.V.2    Geurts, J.3    Yankaya, B.4    Troost, D.5
  • 4
    • 76049118058 scopus 로고    scopus 로고
    • Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms
    • Bradford, J., Shin, J. Y., Roberts, M., Wang, C. E., Li, X. J., and Li, S. (2009). Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms. Proc. Natl. Acad. Sci. U.S.A. 106, 22480-22485. doi: 10.1073/pnas.0911503106.
    • (2009) Proc. Natl. Acad. Sci. U.S.A , vol.106 , pp. 22480-22485
    • Bradford, J.1    Shin, J.Y.2    Roberts, M.3    Wang, C.E.4    Li, X.J.5    Li, S.6
  • 5
    • 84905823855 scopus 로고    scopus 로고
    • Latest treatment options for Alzheimer's disease, Parkinson's disease dementia and dementia with Lewy bodies
    • Broadstock, M., Ballard, C., and Corbett, A. (2014). Latest treatment options for Alzheimer's disease, Parkinson's disease dementia and dementia with Lewy bodies. Expert Opin. Pharmacother. 15, 1797-1810. doi: 10.1517/14656566.2014.936848.
    • (2014) Expert Opin. Pharmacother , vol.15 , pp. 1797-1810
    • Broadstock, M.1    Ballard, C.2    Corbett, A.3
  • 6
    • 4944247976 scopus 로고    scopus 로고
    • Astrocytic degeneration relates to the severity of disease in frontotemporal dementia
    • Broe, M., Kril, J., and Hallidal, G. M. (2004). Astrocytic degeneration relates to the severity of disease in frontotemporal dementia. Brain 127, 2214-2220. doi: 10.1093/brain/awh250.
    • (2004) Brain , vol.127 , pp. 2214-2220
    • Broe, M.1    Kril, J.2    Hallidal, G.M.3
  • 7
    • 0031051485 scopus 로고    scopus 로고
    • ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions
    • Bruijn, L. I., Becher, M. W., Lee, M. K., Anderson, K. L., Jenkins, N. A., Copeland, N. G., et al. (1997). ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron 18, 327-338. doi: 10.1016/S0896-6273(00)80272-X.
    • (1997) Neuron , vol.18 , pp. 327-338
    • Bruijn, L.I.1    Becher, M.W.2    Lee, M.K.3    Anderson, K.L.4    Jenkins, N.A.5    Copeland, N.G.6
  • 8
    • 84907180250 scopus 로고    scopus 로고
    • Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology?
    • Charron, G., Doudnikoff, E., Canron, M. H., Li, Q., Véga, C., Marais, S., et al. (2014). Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology? Front. Aging Neurosci. 6:258. doi: 10.3389/fnagi.2014.00258.
    • (2014) Front. Aging Neurosci , vol.6 , pp. 258
    • Charron, G.1    Doudnikoff, E.2    Canron, M.H.3    Li, Q.4    Véga, C.5    Marais, S.6
  • 10
    • 33749010065 scopus 로고    scopus 로고
    • Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport
    • Custer, S. K., Garden, G. A., Gill, N., Rueb, U., Libby, R. T., Schultz, C., et al. (2006). Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport. Nat. Neurosci. 9, 1302-1311. doi: 10.1038/nn1750.
    • (2006) Nat. Neurosci , vol.9 , pp. 1302-1311
    • Custer, S.K.1    Garden, G.A.2    Gill, N.3    Rueb, U.4    Libby, R.T.5    Schultz, C.6
  • 11
    • 4644255535 scopus 로고    scopus 로고
    • Common pathways of depression and pain
    • Delgado, P. L. (2004). Common pathways of depression and pain. J. Clin. Psychiatry 65(Suppl. 12), 16-19. doi: 10.1016/j.jad.2014.03.051.
    • (2004) J. Clin. Psychiatry , vol.65 , pp. 16-19
    • Delgado, P.L.1
  • 12
    • 77958156339 scopus 로고    scopus 로고
    • In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects
    • Faideau, M., Kim, J., Cormier, K., Gilmore, R., Welch, M., Auregan, G., et al. (2010). In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects. Hum. Mol. Genet. 19, 3053-3067. doi: 10.1093/hmg/ddq212.
    • (2010) Hum. Mol. Genet , vol.19 , pp. 3053-3067
    • Faideau, M.1    Kim, J.2    Cormier, K.3    Gilmore, R.4    Welch, M.5    Auregan, G.6
  • 13
    • 84884144854 scopus 로고    scopus 로고
    • Increased expression of glial fibrillary acidic protein in prefrontal cortex in psychotic illness
    • Feresten, A. H., Barakauskas, V., Ypsilanti, A., Barr, A. M., and Beasley, C. L. (2013). Increased expression of glial fibrillary acidic protein in prefrontal cortex in psychotic illness. Schizophr. Res. 150, 252-257. doi: 10.1016/j.schres.2013.07.024.
    • (2013) Schizophr. Res , vol.150 , pp. 252-257
    • Feresten, A.H.1    Barakauskas, V.2    Ypsilanti, A.3    Barr, A.M.4    Beasley, C.L.5
  • 14
    • 0037096365 scopus 로고    scopus 로고
    • Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice
    • Garden, G. A., Libby, R. T., Fu, Y. H., Kinoshita, Y., Huang, J., Possin, D. E., et al. (2002). Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice. J. Neurosci. 22, 4897-4905. doi: 10.1016/j.neuron.2011.05.027.
    • (2002) J. Neurosci , vol.22 , pp. 4897-4905
    • Garden, G.A.1    Libby, R.T.2    Fu, Y.H.3    Kinoshita, Y.4    Huang, J.5    Possin, D.E.6
  • 15
    • 79952588804 scopus 로고    scopus 로고
    • Bidirectional control of arteriole diameter by astrocytes
    • Gordon, G. R., Howarth, C., and Mac Vicar, V. A. (2011). Bidirectional control of arteriole diameter by astrocytes. Exp. Physiol. 96, 393-399. doi: 10.1113/expphysiol.2010.053132.
    • (2011) Exp. Physiol , vol.96 , pp. 393-399
    • Gordon, G.R.1    Howarth, C.2    Mac Vicar, V.A.3
  • 16
    • 20944431926 scopus 로고    scopus 로고
    • Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice
    • Gu, X., Li, C., Wei, W., Lo, V., Iwasato, T., Itohara, S., et al. (2005). Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron 46, 433-444. doi: 10.1016/j.neuron.2005.03.025.
    • (2005) Neuron , vol.46 , pp. 433-444
    • Gu, X.1    Li, C.2    Wei, W.3    Lo, V.4    Iwasato, T.5    Itohara, S.6
  • 17
    • 79951499176 scopus 로고    scopus 로고
    • Glia: initiators and progressors of pathology in Parkinson's disease
    • Halliday, G. M., and Stevens, C. H. (2011). Glia: initiators and progressors of pathology in Parkinson's disease. Mov. Disord. 26, 6-17. doi: 10.1016/S0197-4580(02)00065-9.
    • (2011) Mov. Disord , vol.26 , pp. 6-17
    • Halliday, G.M.1    Stevens, C.H.2
  • 18
    • 0032924127 scopus 로고    scopus 로고
    • The neuropathology of schizophrenia. A critical review of the data and their interpretation
    • Harrison, P. J. (1999). The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain 122, 593-624. doi: 10.1093/brain/122.4.593.
    • (1999) Brain , vol.122 , pp. 593-624
    • Harrison, P.J.1
  • 19
    • 64949097318 scopus 로고    scopus 로고
    • Astrocytes are a major target in thiamine deficiency and Wernicke's encephalopathy
    • Hazell, A. S. (2009). Astrocytes are a major target in thiamine deficiency and Wernicke's encephalopathy. Neurochem. Int. 55, 129-135. doi: 10.1007/s11064-012-0955-2.
    • (2009) Neurochem. Int , vol.55 , pp. 129-135
    • Hazell, A.S.1
  • 20
    • 8844262582 scopus 로고    scopus 로고
    • Regional and cellular pathology in frontotemporal dementia: relationship to stage of disease in cases with and without Pick bodies
    • Kersaitis, C., Halliday, G. M., and Kril, J. J. (2004). Regional and cellular pathology in frontotemporal dementia: relationship to stage of disease in cases with and without Pick bodies. Acta Neuropathol. 108, 515-523. doi: 10.1007/S00401-004-0917-0.
    • (2004) Acta Neuropathol , vol.108 , pp. 515-523
    • Kersaitis, C.1    Halliday, G.M.2    Kril, J.J.3
  • 21
    • 84933055405 scopus 로고    scopus 로고
    • Diversity of astrocyte functions phenotypes in neural circuits
    • Khakh, B. S., and Sofroniew, M. V. (2015). Diversity of astrocyte functions phenotypes in neural circuits. Nat. Neurosci. 18, 942-952. doi: 10.1038/nn.4043.
    • (2015) Nat. Neurosci , vol.18 , pp. 942-952
    • Khakh, B.S.1    Sofroniew, M.V.2
  • 22
    • 84864359502 scopus 로고    scopus 로고
    • Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer's disease
    • Kulijewicz-Nawrot, M., Verkhratsky, A., Chvátal, A., Syková, E., and Rodríguez, J. J. (2012). Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer's disease. J. Anat. 221, 252-262. doi: 10.1111/j.1469-7580.2012.01536.x.
    • (2012) J. Anat , vol.221 , pp. 252-262
    • Kulijewicz-Nawrot, M.1    Verkhratsky, A.2    Chvátal, A.3    Syková, E.4    Rodríguez, J.J.5
  • 23
    • 80755185727 scopus 로고    scopus 로고
    • Glial cells in amyotrophic lateral sclerosis
    • Lasiene, J., and Yamanaka, K. (2011). Glial cells in amyotrophic lateral sclerosis. Neurol. Res. Int. 2011, 718987. doi: 10.1155/2011/718987.
    • (2011) Neurol. Res. Int , vol.2011
    • Lasiene, J.1    Yamanaka, K.2
  • 24
    • 0023793690 scopus 로고
    • Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases
    • Manetto, V., Perry, G., Tabaton, M., Mulvihill, P., Fried, V. A., Smith, H. T., et al. (1988). Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases. Proc. Natl. Acad. Sci. U.S.A. 85, 4501-4505. doi: 10.1073/pnas.85.12.4501.
    • (1988) Proc. Natl. Acad. Sci. U.S.A , vol.85 , pp. 4501-4505
    • Manetto, V.1    Perry, G.2    Tabaton, M.3    Mulvihill, P.4    Fried, V.A.5    Smith, H.T.6
  • 25
    • 0035836669 scopus 로고    scopus 로고
    • ALS defeats gabapentin: reflections on another failed treatment
    • McDermott, M. P., and Rowland, L. P. (2001). ALS defeats gabapentin: reflections on another failed treatment. Neurology 56, 826-827. doi: 10.1212/WNL.56.7.826.
    • (2001) Neurology , vol.56 , pp. 826-827
    • McDermott, M.P.1    Rowland, L.P.2
  • 26
    • 84868194710 scopus 로고    scopus 로고
    • Astrocytes conspire with neurons during progression of neurological diseases
    • McGann, J. C., Lioy, D. T., and Nabdel, G. (2012). Astrocytes conspire with neurons during progression of neurological diseases. Curr. Opin. Neurobiol. 22, 550-558. doi: 10.1016/j.conb.2012.03.009.
    • (2012) Curr. Opin. Neurobiol , vol.22 , pp. 550-558
    • McGann, J.C.1    Lioy, D.T.2    Nabdel, G.3
  • 27
    • 47349104402 scopus 로고    scopus 로고
    • Glial reactions in Parkinson's disease
    • McGeer, P. L., and McGeer, E. G. (2008). Glial reactions in Parkinson's disease. Mov. Disord. 23, 474-483. doi: 10.1002/mds.21751.
    • (2008) Mov. Disord , vol.23 , pp. 474-483
    • McGeer, P.L.1    McGeer, E.G.2
  • 28
    • 0344845132 scopus 로고    scopus 로고
    • Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
    • Oddo, S., Caccamo, A., Kitazawa, M., Tseng, B. P., and LaFerla, F. M. (2003). Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease. Neurobiol. Aging 24, 1063-1070. doi: 10.1016/S0896-6273(03)00434-3.
    • (2003) Neurobiol. Aging , vol.24 , pp. 1063-1070
    • Oddo, S.1    Caccamo, A.2    Kitazawa, M.3    Tseng, B.P.4    LaFerla, F.M.5
  • 29
    • 77952573750 scopus 로고    scopus 로고
    • Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease
    • Olabarria, M., Noristani, H. N., Verkhratsky, A., and Rodriguez, J. J. (2010). Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease. Glia 58, 831-838. doi: 10.1002/glia.20967.
    • (2010) Glia , vol.58 , pp. 831-838
    • Olabarria, M.1    Noristani, H.N.2    Verkhratsky, A.3    Rodriguez, J.J.4
  • 30
    • 80055074312 scopus 로고    scopus 로고
    • Astrocytes carrying the superoxide dismutase 1(SOD1 G93A) mutation induce wild type motor neuron degeneration in vivo
    • Papadeas, S. T., Kraig, S. E., O'Banion, C., Lepore, A. C., and Maragakis, N. J. (2011). Astrocytes carrying the superoxide dismutase 1(SOD1 G93A) mutation induce wild type motor neuron degeneration in vivo. Proc. Natl. Acad. Sci. U.S.A. 108, 17803-17808. doi: 10.1073/pnas.1103141108.
    • (2011) Proc. Natl. Acad. Sci. U.S.A , vol.108 , pp. 17803-17808
    • Papadeas, S.T.1    Kraig, S.E.2    O'Banion, C.3    Lepore, A.C.4    Maragakis, N.J.5
  • 31
    • 0023462784 scopus 로고
    • Cytoskeletal pathology in neurodegenerative diseases
    • Pendlebury, W. W., Munoz-Garcia, D., and Perl, D. P. (1987). Cytoskeletal pathology in neurodegenerative diseases. Adv. Exp. Med. Biol. 221, 427-442. doi: 10.1002/ana.410420403.
    • (1987) Adv. Exp. Med. Biol , vol.221 , pp. 427-442
    • Pendlebury, W.W.1    Munoz-Garcia, D.2    Perl, D.P.3
  • 32
    • 84885444054 scopus 로고    scopus 로고
    • Microglia actions In Alzheimer's disease
    • Prokop, P. S., Miller, K. R., and Heppner, S. L. (2013). Microglia actions In Alzheimer's disease. Acta Neuropathol. 126, 461-477. doi: 10.1007/s00401-013-1182-x.
    • (2013) Acta Neuropathol , vol.126 , pp. 461-477
    • Prokop, P.S.1    Miller, K.R.2    Heppner, S.L.3
  • 33
  • 34
    • 84896689426 scopus 로고    scopus 로고
    • Glutamine in the pathogenesis of hepatic encephalopathy: the trojan horse hypothesis revisited
    • Rama Rao, K. V., and Norenberg, M. D. (2014). Glutamine in the pathogenesis of hepatic encephalopathy: the trojan horse hypothesis revisited. Neurochem. Res. 39, 593-598. doi: 10.1007/s11064-012-0955-2.
    • (2014) Neurochem. Res , vol.39 , pp. 593-598
    • Rama Rao, K.V.1    Norenberg, M.D.2
  • 35
    • 84864332612 scopus 로고    scopus 로고
    • Connexin composition in apposed gap junction hemiplaques revealed by matched double-replica freeze-fracture replica immunogold labeling
    • Rash, J. E., Kamasawa, N., Davidson, K. G., Yasumura, T., Pereda, A. E., and Nagy, J. I. (2012). Connexin composition in apposed gap junction hemiplaques revealed by matched double-replica freeze-fracture replica immunogold labeling. J. Membr. Biol. 245, 333-344. doi: 10.1007/s00232-012-9454-2.
    • (2012) J. Membr. Biol , vol.245 , pp. 333-344
    • Rash, J.E.1    Kamasawa, N.2    Davidson, K.G.3    Yasumura, T.4    Pereda, A.E.5    Nagy, J.I.6
  • 36
    • 77952410964 scopus 로고    scopus 로고
    • Morphology and dynamics of perisynaptic glia
    • Reichenbach, A., Derouiche, A., and Kirchhoff, F. (2010). Morphology and dynamics of perisynaptic glia. Brain Res. Rev. 63, 11-25. doi: 10.1016/j.brainresrev.2010.02.003.
    • (2010) Brain Res. Rev , vol.63 , pp. 11-25
    • Reichenbach, A.1    Derouiche, A.2    Kirchhoff, F.3
  • 37
    • 0026562846 scopus 로고
    • Chronic encephalopathies induced by mercury or lead: aspects of underlying cellular and molecular mechanisms
    • Rönnbäck, L., and Hansson, E. (1992). Chronic encephalopathies induced by mercury or lead: aspects of underlying cellular and molecular mechanisms. Br. J. Ind. Med. 49, 233-240. doi: 10.1136/oem.49.4.233.
    • (1992) Br. J. Ind. Med , vol.49 , pp. 233-240
    • Rönnbäck, L.1    Hansson, E.2
  • 39
    • 84945453289 scopus 로고    scopus 로고
    • Control of autoimmune CNS inflammation by astrocytes
    • Rothhammer, V., and Quintana, F. J. (2015). Control of autoimmune CNS inflammation by astrocytes. Semin. Immunopathol. 37, 625-638. doi: 10.1007/s00281-015-0515-3.
    • (2015) Semin. Immunopathol , vol.37 , pp. 625-638
    • Rothhammer, V.1    Quintana, F.J.2
  • 40
    • 29144460321 scopus 로고    scopus 로고
    • Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity
    • Shin, J. Y., Fang, Z. H., Yu, Z. X., Wang, C. E., Li, S. H., and Li, X. J. (2005). Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. J. Cell Biol. 171, 1001-1012. doi: 10.1083/jcb.200508072.
    • (2005) J. Cell Biol , vol.171 , pp. 1001-1012
    • Shin, J.Y.1    Fang, Z.H.2    Yu, Z.X.3    Wang, C.E.4    Li, S.H.5    Li, X.J.6
  • 41
    • 84869082837 scopus 로고    scopus 로고
    • Is amyotrophic lateral sclerosis a primary astrocytic disease?
    • Sica, R. E. (2012). Is amyotrophic lateral sclerosis a primary astrocytic disease? Med. Hypotheses 79, 819-822. doi: 10.1016/j.mehy.2012.08.036.
    • (2012) Med. Hypotheses , vol.79 , pp. 819-822
    • Sica, R.E.1
  • 42
    • 84925705269 scopus 로고    scopus 로고
    • Could astrocytes be the primary target of an offending agent causing the primary degenerative diseases of the human central nervous system? A hypothesis
    • Sica, R. E. (2015). Could astrocytes be the primary target of an offending agent causing the primary degenerative diseases of the human central nervous system? A hypothesis. Med. Hyphoteses 84, 481-489. doi: 10.1016/j.mehy.2015.02.004.
    • (2015) Med. Hyphoteses , vol.84 , pp. 481-489
    • Sica, R.E.1
  • 43
    • 77049085956 scopus 로고    scopus 로고
    • MRC cognitive function and ageing neuropathology study group. Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain
    • Simpson, J. E., Ince, P. G., Lace, G., Forster, G., Shaw, P. J., Matthews, F., et al. (2010). MRC cognitive function and ageing neuropathology study group. Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain. Neurobiol. Aging 31, 578-590. doi: 10.1016/j.neurobiolaging.2008.05.015.
    • (2010) Neurobiol. Aging , vol.31 , pp. 578-590
    • Simpson, J.E.1    Ince, P.G.2    Lace, G.3    Forster, G.4    Shaw, P.J.5    Matthews, F.6
  • 44
    • 84880217322 scopus 로고    scopus 로고
    • Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats
    • Tong, J., Huang, C., Bi, F., Wu, Q., Huang, B., Liu, X., et al. (2013). Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats. EMBO J. 32, 1917-1926. doi: 10.1038/emboj.2013.122.
    • (2013) EMBO J , vol.32 , pp. 1917-1926
    • Tong, J.1    Huang, C.2    Bi, F.3    Wu, Q.4    Huang, B.5    Liu, X.6
  • 45
    • 84942596257 scopus 로고    scopus 로고
    • Glial asthenia and functional paralysis: a new perspective on neurodegeneration and Alzheimer's disease
    • [Epub ahead of print].
    • Verkhratsky, A., Marutle, A., Rodríguez-Arellano, J. J., and Nordberg, A. (2014a). Glial asthenia and functional paralysis: a new perspective on neurodegeneration and Alzheimer's disease. Neuroscientist doi: 10.1177/1073858414547132 [Epub ahead of print].
    • (2014) Neuroscientist
    • Verkhratsky, A.1    Marutle, A.2    Rodríguez-Arellano, J.J.3    Nordberg, A.4
  • 46
    • 84910622895 scopus 로고    scopus 로고
    • Astrogliopathology: a central element of neuropsychiatric diseases?
    • Verkhratsky, A., Rodríguez, J. J., and Steardo, L. (2014b). Astrogliopathology: a central element of neuropsychiatric diseases? Neuroscientist 20, 576-588. doi: 10.1177/1073858413510208.
    • (2014) Neuroscientist , vol.20 , pp. 576-588
    • Verkhratsky, A.1    Rodríguez, J.J.2    Steardo, L.3
  • 48
    • 84949727759 scopus 로고    scopus 로고
    • Astrogliopathology in neurological, neurodevelopmental and psychiatric disorders
    • Verkhratsky, A., and Parpura, V. (2015). Astrogliopathology in neurological, neurodevelopmental and psychiatric disorders. Neurobiol. Dis. 3, 1-8. doi: 10.1016/j.nbd.2015.03.025.
    • (2015) Neurobiol. Dis , vol.3 , pp. 1-8
    • Verkhratsky, A.1    Parpura, V.2
  • 49
    • 65449133591 scopus 로고    scopus 로고
    • MRC Cognitive Function and Ageing Neuropathology Study Group. Population variation in glial fibrillary acidic protein levels in brain ageing: relationship to Alzheimer-type pathology and dementia
    • Wharton, S. B., O'Callaghan, J. P., Savva, G. M., Nicoll, J. A., Matthews, F., Simpson, J. E., et al. (2009). MRC Cognitive Function and Ageing Neuropathology Study Group. Population variation in glial fibrillary acidic protein levels in brain ageing: relationship to Alzheimer-type pathology and dementia. Dement. Geriatr. Cogn. Disord. 27, 465-473. doi: 10.1159/000217729.
    • (2009) Dement. Geriatr. Cogn. Disord , vol.27 , pp. 465-473
    • Wharton, S.B.1    O'Callaghan, J.P.2    Savva, G.M.3    Nicoll, J.A.4    Matthews, F.5    Simpson, J.E.6
  • 50
    • 39749188753 scopus 로고    scopus 로고
    • Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
    • Yamanaka, K., Chun, S. J., Boillee, S., Fujimori-Tonou, N., Yamashita, H., Gutmann, D. H., et al. (2008). Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nat. Neurosci. 11, 251-253. doi: 10.1038/nn2047.
    • (2008) Nat. Neurosci , vol.11 , pp. 251-253
    • Yamanaka, K.1    Chun, S.J.2    Boillee, S.3    Fujimori-Tonou, N.4    Yamashita, H.5    Gutmann, D.H.6
  • 51
    • 84856990170 scopus 로고    scopus 로고
    • Early astrocytic atrophy in the entorhinal cortex of a triple transgenic animal model of Alzheimer's disease
    • Yeh, C. Y., Vadhwana, B., Verkhratsky, A., and Rodriguez, J. J. (2011). Early astrocytic atrophy in the entorhinal cortex of a triple transgenic animal model of Alzheimer's disease. ASN Neuro 3, 271-279. doi: 10.1042/AN20110025.
    • (2011) ASN Neuro , vol.3 , pp. 271-279
    • Yeh, C.Y.1    Vadhwana, B.2    Verkhratsky, A.3    Rodriguez, J.J.4


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