Mapping the Human Platelet Lipidome Reveals Cytosolic Phospholipase A 2 as a Regulator of Mitochondrial Bioenergetics during Activation

Cell Metabolism

Volumn 23, Issue 5, 2016, Pages 930-944

  Slatter, David A ^a   Aldrovandi, Maceler ^a   O'Connor, Anne ^a   Allen, Stuart M ^a   Brasher, Christopher J ^a   Murphy, Robert C ^b   Mecklemann, Sven ^a   Ravi, Saranya ^c   Darley Usmar, Victor ^c   O'Donnell, Valerie B ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMINOPHOSPHOLIPID; CYCLOOXYGENASE 1; FATTY ACID; LIPIDOME; PHOSPHOLIPASE A2; THROMBIN; CYTOSOLIC PHOSPHOLIPASE A2; ICOSANOID; PHOSPHOLIPID;

ARTICLE; BIOENERGY; CONTROLLED STUDY; CYTOSOL; ENERGY METABOLISM; ENZYME ACTIVITY; FATTY ACID ANALYSIS; GLYCOLYSIS; HUMAN; HUMAN CELL; LIPID MEMBRANE; LIPIDOMICS; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL RESPIRATION; NORMAL HUMAN; OXIDATION; POSITIVE FEEDBACK; PRIORITY JOURNAL; REGULATORY MECHANISM; THROMBOCYTE ACTIVATION; THROMBOCYTE MEMBRANE; UNRELATED DONORS; DRUG EFFECT; ENZYME ACTIVATION; ENZYME SPECIFICITY; LIPID METABOLISM; METABOLISM; METABOLOME; MITOCHONDRION; OXIDATION REDUCTION REACTION; SIGNAL TRANSDUCTION; THROMBOCYTE; TIME FACTOR;

ASPIRIN; BLOOD PLATELETS; EICOSANOIDS; ENERGY METABOLISM; ENZYME ACTIVATION; FATTY ACIDS; HUMANS; LIPID METABOLISM; METABOLOME; MITOCHONDRIA; OXIDATION-REDUCTION; PHOSPHOLIPASES A2, CYTOSOLIC; PHOSPHOLIPIDS; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; THROMBIN; TIME FACTORS;

EID: 84964658618     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.04.001     Document Type: Article

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