메뉴 건너뛰기




Volumn 23, Issue 5, 2016, Pages 837-851

Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; INCRETIN; GLUCOSE; INSULIN; TESTOSTERONE;

EID: 84964589443     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.03.015     Document Type: Article
Times cited : (136)

References (50)
  • 1
    • 0034001450 scopus 로고    scopus 로고
    • Autonomic regulation of islet hormone secretion - Implications for health and disease
    • B. Ahrén Autonomic regulation of islet hormone secretion - implications for health and disease Diabetologia 43 2000 393 410
    • (2000) Diabetologia , vol.43 , pp. 393-410
    • Ahrén, B.1
  • 2
    • 0018892185 scopus 로고
    • Glucoreceptor mechanisms and the control of insulin release and biosynthesis
    • S.J. Ashcroft Glucoreceptor mechanisms and the control of insulin release and biosynthesis Diabetologia 18 1980 5 15
    • (1980) Diabetologia , vol.18 , pp. 5-15
    • Ashcroft, S.J.1
  • 3
    • 31544440178 scopus 로고    scopus 로고
    • Hyperglycemia and insulin resistance in men with prostate carcinoma who receive androgen-deprivation therapy
    • S. Basaria, D.C. Muller, M.A. Carducci, J. Egan, and A.S. Dobs Hyperglycemia and insulin resistance in men with prostate carcinoma who receive androgen-deprivation therapy Cancer 106 2006 581 588
    • (2006) Cancer , vol.106 , pp. 581-588
    • Basaria, S.1    Muller, D.C.2    Carducci, M.A.3    Egan, J.4    Dobs, A.S.5
  • 4
    • 0014430280 scopus 로고
    • The intranuclear binding of testosterone and 5-alpha-androstan-17-beta-ol-3-one by rat prostate
    • N. Bruchovsky, and J.D. Wilson The intranuclear binding of testosterone and 5-alpha-androstan-17-beta-ol-3-one by rat prostate J. Biol. Chem. 243 1968 5953 5960
    • (1968) J. Biol. Chem. , vol.243 , pp. 5953-5960
    • Bruchovsky, N.1    Wilson, J.D.2
  • 5
    • 0023929785 scopus 로고
    • Molecular cloning of human and rat complementary DNA encoding androgen receptors
    • C.S. Chang, J. Kokontis, and S.T. Liao Molecular cloning of human and rat complementary DNA encoding androgen receptors Science 240 1988 324 326
    • (1988) Science , vol.240 , pp. 324-326
    • Chang, C.S.1    Kokontis, J.2    Liao, S.T.3
  • 7
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • D.J. Drucker, and M.A. Nauck The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes Lancet 368 2006 1696 1705
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 8
    • 0036342717 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 augments insulin-mediated glucose uptake in the obese state
    • J.M. Egan, G.S. Meneilly, J.F. Habener, and D. Elahi Glucagon-like peptide-1 augments insulin-mediated glucose uptake in the obese state J. Clin. Endocrinol. Metab. 87 2002 3768 3773
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 3768-3773
    • Egan, J.M.1    Meneilly, G.S.2    Habener, J.F.3    Elahi, D.4
  • 9
    • 16244382558 scopus 로고    scopus 로고
    • Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion
    • W. Fan, T. Yanase, M. Nomura, T. Okabe, K. Goto, T. Sato, H. Kawano, S. Kato, and H. Nawata Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion Diabetes 54 2005 1000 1008
    • (2005) Diabetes , vol.54 , pp. 1000-1008
    • Fan, W.1    Yanase, T.2    Nomura, M.3    Okabe, T.4    Goto, K.5    Sato, T.6    Kawano, H.7    Kato, S.8    Nawata, H.9
  • 11
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells
    • R. Göke, H.C. Fehmann, T. Linn, H. Schmidt, M. Krause, J. Eng, and B. Göke Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells J. Biol. Chem. 268 1993 19650 19655
    • (1993) J. Biol. Chem. , vol.268 , pp. 19650-19655
    • Göke, R.1    Fehmann, H.C.2    Linn, T.3    Schmidt, H.4    Krause, M.5    Eng, J.6    Göke, B.7
  • 12
    • 0029798474 scopus 로고    scopus 로고
    • Low levels of sex hormone-binding globulin and testosterone are associated with smaller, denser low density lipoprotein in normoglycemic men
    • S.M. Haffner, M. Laakso, H. Miettinen, L. Mykkänen, P. Karhapää, and D.L. Rainwater Low levels of sex hormone-binding globulin and testosterone are associated with smaller, denser low density lipoprotein in normoglycemic men J. Clin. Endocrinol. Metab. 81 1996 3697 3701
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 3697-3701
    • Haffner, S.M.1    Laakso, M.2    Miettinen, H.3    Mykkänen, L.4    Karhapää, P.5    Rainwater, D.L.6
  • 13
    • 84884182849 scopus 로고    scopus 로고
    • Prediabetes is associated with an increased risk of testosterone deficiency, independent of obesity and metabolic syndrome
    • C.H. Ho, H.J. Yu, C.Y. Wang, F.S. Jaw, J.T. Hsieh, W.C. Liao, Y.S. Pu, and S.P. Liu Prediabetes is associated with an increased risk of testosterone deficiency, independent of obesity and metabolic syndrome PLoS ONE 8 2013 e74173
    • (2013) PLoS ONE , vol.8 , pp. e74173
    • Ho, C.H.1    Yu, H.J.2    Wang, C.Y.3    Jaw, F.S.4    Hsieh, J.T.5    Liao, W.C.6    Pu, Y.S.7    Liu, S.P.8
  • 14
    • 9644270534 scopus 로고    scopus 로고
    • Marked hyperglycemia after androgen-deprivation therapy for prostate cancer and usefulness of pioglitazone for its treatment
    • M. Inaba, Y. Otani, K. Nishimura, N. Takaha, A. Okuyama, M. Koga, J. Azuma, I. Kawase, and S. Kasayama Marked hyperglycemia after androgen-deprivation therapy for prostate cancer and usefulness of pioglitazone for its treatment Metabolism 54 2005 55 59
    • (2005) Metabolism , vol.54 , pp. 55-59
    • Inaba, M.1    Otani, Y.2    Nishimura, K.3    Takaha, N.4    Okuyama, A.5    Koga, M.6    Azuma, J.7    Kawase, I.8    Kasayama, S.9
  • 15
    • 34147114221 scopus 로고    scopus 로고
    • Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate
    • D.A. Jacobson, C.R. Weber, S. Bao, J. Turk, and L.H. Philipson Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate J. Biol. Chem. 282 2007 7442 7449
    • (2007) J. Biol. Chem. , vol.282 , pp. 7442-7449
    • Jacobson, D.A.1    Weber, C.R.2    Bao, S.3    Turk, J.4    Philipson, L.H.5
  • 16
    • 0022270684 scopus 로고
    • Effects of Ca2+ and a phorbol ester on insulin secretion from islets of Langerhans permeabilised by high-voltage discharge
    • P.M. Jones, J. Stutchfield, and S.L. Howell Effects of Ca2+ and a phorbol ester on insulin secretion from islets of Langerhans permeabilised by high-voltage discharge FEBS Lett. 191 1985 102 106
    • (1985) FEBS Lett. , vol.191 , pp. 102-106
    • Jones, P.M.1    Stutchfield, J.2    Howell, S.L.3
  • 17
    • 84876532885 scopus 로고    scopus 로고
    • β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion
    • K.A. Kaihara, L.M. Dickson, D.A. Jacobson, N. Tamarina, M.W. Roe, L.H. Philipson, and B. Wicksteed β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion Diabetes 62 2013 1527 1536
    • (2013) Diabetes , vol.62 , pp. 1527-1536
    • Kaihara, K.A.1    Dickson, L.M.2    Jacobson, D.A.3    Tamarina, N.4    Roe, M.W.5    Philipson, L.H.6    Wicksteed, B.7
  • 18
    • 85044696429 scopus 로고    scopus 로고
    • Diabetes and cardiovascular disease during androgen deprivation therapy: Observational study of veterans with prostate cancer
    • N.L. Keating, A. O'Malley, S.J. Freedland, and M.R. Smith Diabetes and cardiovascular disease during androgen deprivation therapy: observational study of veterans with prostate cancer J. Natl. Cancer Inst. 104 2012 1518 1523
    • (2012) J. Natl. Cancer Inst. , vol.104 , pp. 1518-1523
    • Keating, N.L.1    O'Malley, A.2    Freedland, S.J.3    Smith, M.R.4
  • 19
    • 0026761599 scopus 로고
    • Lower endogenous androgens predict central adiposity in men
    • K.T. Khaw, and E. Barrett-Connor Lower endogenous androgens predict central adiposity in men Ann. Epidemiol. 2 1992 675 682
    • (1992) Ann. Epidemiol. , vol.2 , pp. 675-682
    • Khaw, K.T.1    Barrett-Connor, E.2
  • 20
    • 0015416752 scopus 로고
    • Perifusion of isolated rat islets in vitro. Participation of the microtubular system in the biphasic release of insulin
    • P.E. Lacy, M.M. Walker, and C.J. Fink Perifusion of isolated rat islets in vitro. Participation of the microtubular system in the biphasic release of insulin Diabetes 21 1972 987 998
    • (1972) Diabetes , vol.21 , pp. 987-998
    • Lacy, P.E.1    Walker, M.M.2    Fink, C.J.3
  • 22
    • 0015594439 scopus 로고
    • Effects of some modifiers of insulin secretion on insulin biosynthesis
    • B.J. Lin, and R.E. Haist Effects of some modifiers of insulin secretion on insulin biosynthesis Endocrinology 92 1973 735 742
    • (1973) Endocrinology , vol.92 , pp. 735-742
    • Lin, B.J.1    Haist, R.E.2
  • 23
    • 79960907300 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 (SDF-1)/chemokine (C-X-C motif) receptor 4 (CXCR4) axis activation induces intra-islet glucagon-like peptide-1 (GLP-1) production and enhances beta cell survival
    • Z. Liu, V. Stanojevic, S. Avadhani, T. Yano, and J.F. Habener Stromal cell-derived factor-1 (SDF-1)/chemokine (C-X-C motif) receptor 4 (CXCR4) axis activation induces intra-islet glucagon-like peptide-1 (GLP-1) production and enhances beta cell survival Diabetologia 54 2011 2067 2076
    • (2011) Diabetologia , vol.54 , pp. 2067-2076
    • Liu, Z.1    Stanojevic, V.2    Avadhani, S.3    Yano, T.4    Habener, J.F.5
  • 24
    • 0023910355 scopus 로고
    • Cloning of human androgen receptor complementary DNA and localization to the X chromosome
    • D.B. Lubahn, D.R. Joseph, P.M. Sullivan, H.F. Willard, F.S. French, and E.M. Wilson Cloning of human androgen receptor complementary DNA and localization to the X chromosome Science 240 1988 327 330
    • (1988) Science , vol.240 , pp. 327-330
    • Lubahn, D.B.1    Joseph, D.R.2    Sullivan, P.M.3    Willard, H.F.4    French, F.S.5    Wilson, E.M.6
  • 27
    • 78650521925 scopus 로고    scopus 로고
    • Estrogen and androgen receptors: Regulators of fuel homeostasis and emerging targets for diabetes and obesity
    • F. Mauvais-Jarvis Estrogen and androgen receptors: regulators of fuel homeostasis and emerging targets for diabetes and obesity Trends Endocrinol. Metab. 22 2011 24 33
    • (2011) Trends Endocrinol. Metab. , vol.22 , pp. 24-33
    • Mauvais-Jarvis, F.1
  • 28
    • 67549142234 scopus 로고    scopus 로고
    • Nonsteroidal selective androgen receptor modulators (SARMs): Dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit
    • M.L. Mohler, C.E. Bohl, A. Jones, C.C. Coss, R. Narayanan, Y. He, D.J. Hwang, J.T. Dalton, and D.D. Miller Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit J. Med. Chem. 52 2009 3597 3617
    • (2009) J. Med. Chem. , vol.52 , pp. 3597-3617
    • Mohler, M.L.1    Bohl, C.E.2    Jones, A.3    Coss, C.C.4    Narayanan, R.5    He, Y.6    Hwang, D.J.7    Dalton, J.T.8    Miller, D.D.9
  • 30
    • 0036314213 scopus 로고    scopus 로고
    • Beta-cell protein kinases and the dynamics of the insulin response to glucose
    • R. Nesher, E. Anteby, M. Yedovizky, N. Warwar, N. Kaiser, and E. Cerasi Beta-cell protein kinases and the dynamics of the insulin response to glucose Diabetes 51 Suppl 1 2002 S68 S73
    • (2002) Diabetes , vol.51 , pp. S68-S73
    • Nesher, R.1    Anteby, E.2    Yedovizky, M.3    Warwar, N.4    Kaiser, N.5    Cerasi, E.6
  • 31
    • 0036357643 scopus 로고    scopus 로고
    • Endogenous sex hormones and the development of type 2 diabetes in older men and women: The Rancho Bernardo study
    • J.Y. Oh, E. Barrett-Connor, N.M. Wedick, D.L. Wingard Rancho Bernardo Study Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo study Diabetes Care 25 2002 55 60
    • (2002) Diabetes Care , vol.25 , pp. 55-60
    • Oh, J.Y.1    Barrett-Connor, E.2    Wedick, N.M.3    Wingard, D.L.4
  • 34
    • 28844481089 scopus 로고    scopus 로고
    • Molecular chaperones throughout the life cycle of the androgen receptor
    • J. Prescott, and G.A. Coetzee Molecular chaperones throughout the life cycle of the androgen receptor Cancer Lett. 231 2006 12 19
    • (2006) Cancer Lett. , vol.231 , pp. 12-19
    • Prescott, J.1    Coetzee, G.A.2
  • 35
    • 0030062098 scopus 로고    scopus 로고
    • Neuron-specific gene expression of synapsin I. Major role of a negative regulatory mechanism
    • S. Schoch, G. Cibelli, and G. Thiel Neuron-specific gene expression of synapsin I. Major role of a negative regulatory mechanism J. Biol. Chem. 271 1996 3317 3323
    • (1996) J. Biol. Chem. , vol.271 , pp. 3317-3323
    • Schoch, S.1    Cibelli, G.2    Thiel, G.3
  • 38
    • 0034106347 scopus 로고    scopus 로고
    • Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: Prospective results from the Massachusetts male aging study
    • R.K. Stellato, H.A. Feldman, O. Hamdy, E.S. Horton, and J.B. McKinlay Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging study Diabetes Care 23 2000 490 494
    • (2000) Diabetes Care , vol.23 , pp. 490-494
    • Stellato, R.K.1    Feldman, H.A.2    Hamdy, O.3    Horton, E.S.4    McKinlay, J.B.5
  • 39
    • 84862219400 scopus 로고    scopus 로고
    • Selective estrogen receptor modulation in pancreatic β-cells and the prevention of type 2 diabetes
    • J. Tiano, and F. Mauvais-Jarvis Selective estrogen receptor modulation in pancreatic β-cells and the prevention of type 2 diabetes Islets 4 2012 173 176
    • (2012) Islets , vol.4 , pp. 173-176
    • Tiano, J.1    Mauvais-Jarvis, F.2
  • 40
    • 84861335162 scopus 로고    scopus 로고
    • Importance of oestrogen receptors to preserve functional β-cell mass in diabetes
    • J.P. Tiano, and F. Mauvais-Jarvis Importance of oestrogen receptors to preserve functional β-cell mass in diabetes Nat. Rev. Endocrinol. 8 2012 342 351
    • (2012) Nat. Rev. Endocrinol. , vol.8 , pp. 342-351
    • Tiano, J.P.1    Mauvais-Jarvis, F.2
  • 41
    • 84862737646 scopus 로고    scopus 로고
    • Molecular mechanisms of estrogen receptors' suppression of lipogenesis in pancreatic β-cells
    • J.P. Tiano, and F. Mauvais-Jarvis Molecular mechanisms of estrogen receptors' suppression of lipogenesis in pancreatic β-cells Endocrinology 153 2012 2997 3005
    • (2012) Endocrinology , vol.153 , pp. 2997-3005
    • Tiano, J.P.1    Mauvais-Jarvis, F.2
  • 47
    • 84873046500 scopus 로고    scopus 로고
    • Neuronal androgen receptor regulates insulin sensitivity via suppression of hypothalamic NF-κB-mediated PTP1B expression
    • I.C. Yu, H.Y. Lin, N.C. Liu, J.D. Sparks, S. Yeh, L.Y. Fang, L. Chen, and C. Chang Neuronal androgen receptor regulates insulin sensitivity via suppression of hypothalamic NF-κB-mediated PTP1B expression Diabetes 62 2013 411 423
    • (2013) Diabetes , vol.62 , pp. 411-423
    • Yu, I.C.1    Lin, H.Y.2    Liu, N.C.3    Sparks, J.D.4    Yeh, S.5    Fang, L.Y.6    Chen, L.7    Chang, C.8
  • 48
    • 0642373691 scopus 로고    scopus 로고
    • Androgen-induced prostate-specific antigen gene expression is mediated via dihydrotestosterone in LNCaP cells
    • Y.S. Zhu, L.Q. Cai, X. You, J.J. Cordero, Y. Huang, and J. Imperato-McGinley Androgen-induced prostate-specific antigen gene expression is mediated via dihydrotestosterone in LNCaP cells J. Androl. 24 2003 681 687
    • (2003) J. Androl. , vol.24 , pp. 681-687
    • Zhu, Y.S.1    Cai, L.Q.2    You, X.3    Cordero, J.J.4    Huang, Y.5    Imperato-McGinley, J.6
  • 49
    • 70849117428 scopus 로고    scopus 로고
    • Testosterone deficiency, insulin resistance and the metabolic syndrome
    • M. Zitzmann Testosterone deficiency, insulin resistance and the metabolic syndrome Nat. Rev. Endocrinol. 5 2009 673 681
    • (2009) Nat. Rev. Endocrinol. , vol.5 , pp. 673-681
    • Zitzmann, M.1
  • 50
    • 33751533215 scopus 로고    scopus 로고
    • Association of specific symptoms and metabolic risks with serum testosterone in older men
    • M. Zitzmann, S. Faber, and E. Nieschlag Association of specific symptoms and metabolic risks with serum testosterone in older men J. Clin. Endocrinol. Metab. 91 2006 4335 4343
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 4335-4343
    • Zitzmann, M.1    Faber, S.2    Nieschlag, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.