MRI visual rating scales in the diagnosis of dementia: Evaluation in 184 post-mortem confirmed cases

Brain

Volumn 139, Issue 4, 2016, Pages 1211-1225

  Harper, Lorna ^a   Fumagalli, Giorgio G ^b   Barkhof, Frederik ^c   Scheltens, Philip ^c   O'Brien, John T ^d   Bouwman, Femke ^c   Burton, Emma J ^e   Rohrer, Jonathan D ^a   Fox, Nick C ^a   Ridgway, Gerard R ^f,g   Schott, Jonathan M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF MILAN   (Italy)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e NEWCASTLE UNIVERSITY   (United Kingdom)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

brain atrophy; dementia; MRI; neuropathology; visual rating

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ANTERIOR CINGULATE; ARTICLE; AUTOPSY; BRAIN ATROPHY; BRAIN REGION; BRAIN SIZE; CONTROLLED STUDY; DEMENTIA; DIAGNOSTIC VALUE; DIFFUSE LEWY BODY DISEASE; FEMALE; FRONTOTEMPORAL DEMENTIA; GOLD STANDARD; GRAY MATTER; HISTOPATHOLOGY; HUMAN; INTERRATER RELIABILITY; MACHINE LEARNING; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RATING SCALE; SUPPORT VECTOR MACHINE; VISUAL RATING SCALE; VOXEL BASED MORPHOMETRY; BRAIN CORTEX; CLINICAL TRIAL; FRONTOTEMPORAL LOBAR DEGENERATION; LEWY BODY DISEASE; MIDDLE AGED; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; STANDARDS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AUTOPSY; CEREBRAL CORTEX; DEMENTIA; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; HUMANS; LEWY BODY DISEASE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS;

EID: 84964474512     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/aww005     Document Type: Article

References (59)

1. Ahmed RM, Paterson RW, Warren JD, Zetterberg H, O'Brien JT, Fox NC, et al. Biomarkers in dementia: clinical utility and new directions. J. Neurol Neurosurg Psychiatry 2014; 85: 1426-34.
2. Ambikairajah A, Devenney E, Flanagan E, Yew B, Mioshi E, Kiernan MC, et al. A visual MRI atrophy rating scale for the amyotrophic lateral sclerosis-frontotemporal dementia continuum. [Internet]. Amyotroph Lateral Scler Front Degener 2014; 15: 226-34.
3. Ashburner J. A fast diffeomorphic image registration algorithm. Neuroimage 2007; 38: 95-113.
4. Ashburner J, Friston KJ. Unified segmentation. Neuroimage 2005; 26: 839-51.
5. Ashburner J, Friston KJ. Computing average shaped tissue probability templates. NeuroImage 2009; 45: 333-41.
6. Barkhof F, Polvikoski TM, van Straaten ECW, Kalaria RN, Sulkava R, Aronen HJ, et al. The significance of medial temporal lobe atrophy: a postmortem MRI study in the very old. Neurology 2007; 69: 1521-7.
7. Beach TG, Monsell SE, Phillips LE, Kukull W. Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer Disease Centers, 2005-2010. J Neuropathol Exp Neurol 2012; 71: 266-73.
8. Burton EJ, Barber R, Mukaetova-Ladinska EB, Robson J, Perry RH, Jaros E, et al. Medial temporal lobe atrophy on MRI differentiates Alzheimer's disease from dementia with Lewy bodies and vascular cognitive impairment: a prospective study with pathological verification of diagnosis. Brain 2009; 132: 195-203.
9. Cardoso MJ, Leung K, Modat M, Keihaninejad S, Cash D, Barnes J, et al. STEPS: Similarity and Truth Estimation for Propagated Segmentations and its application to hippocampal segmentation and brain parcelation. Med Image Anal 2013; 17: 671-84.
10. Coupé P, Eskildsen SF, Manjón JV, Fonov VS, Pruessner JC, Allard M, et al. Scoring by nonlocal image patch estimator for early detection of Alzheimer's disease. NeuroImage Clin 2012; 1: 141-52.
11. Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis: I. Segmentation and surface reconstruction. NeuroImage 1999; 9: 179-94.
12. Davies RR, Kipps CM, Mitchell J, Kril JJ, Halliday GM, Hodges JR. Progression in frontotemporal dementia: identifying a benign behavioral variant by magnetic resonance imaging. Arch Neurol 2006; 63: 1627-31.
13. Davies RR, Scahill VL, Graham A, Williams GB, Graham KS, Hodges JR. Development of an MRI rating scale for multiple brain regions: comparison with volumetrics and with voxel-based morphometry. Neuroradiology 2009; 51: 491-503.
14. Duara R, Loewenstein DA, Greig M, Acevedo A, Potter E, Appel J, et al. Reliability and validity of an algorithm for the diagnosis of normal cognition, mild cognitive impairment, and dementia: implications for multicenter research studies. Am J Geriatr Psychiatry 2010; 18: 363-70.
15. Duara R, Loewenstein DA, Shen Q, Barker W, Varon D, Greig MT, et al. The utility of age-specific cut-offs for visual rating of medial temporal atrophy in classifying Alzheimer's disease, MCI and cognitively normal elderly subjects. Front Aging Neurosci 2013; 5: 47
16. Dubois B, Feldman HH, Jacova C, Dekosky ST, Barberger-Gateau P, Cummings J, et al. Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurol 2007; 6: 734-46.
17. Ewers M, Mattsson N, Minthon L, Molinuevo JL, Antonell A, Popp J, et al. CSF biomarkers for the differential diagnosis of Alzheimer's disease: a large-scale international multicenter study. Alzheimers Dement J Alzheimers Assoc 2015; 11: 1306-15.
18. Ferreira D, Cavallin L, Larsson E-M, Muehlboeck J-S, Mecocci P, Vellas B, et al. Practical cut-offs for visual rating scales of medial temporal, frontal and posterior atrophy in Alzheimer's disease and mild cognitive impairment. J Intern. Med 2015; 278: 277-90.
19. Fö rstl H, Burns A, Luthert P, Cairns N, Levy R. The Lewy-body variant of Alzheimer's disease. Clinical and pathological findings. Br J Psychiatry 1993; 162: 385-92.
20. Freeborough PA, Fox NC, Kitney RI. Interactive algorithms for the segmentation and quantitation of 3-D MRI brain scans. Comput Methods Programs Biomed 1997; 53: 15-25.
21. Fumagalli GG, Gordon E, Harper L, Lehmann M, Hyare H, Warren JD, et al. 9th International Conference on Frontotemporal Dementias P.252 Development of a visual rating scale for atrophy of the anterior cingulate, insula and frontal lobes. Am J Neurodegener Dis 2014; 3: 1-375.
22. Galton CJ, Gomez-Anson B, Antoun N, Scheltens P, Patterson K, Graves M, et al. Temporal lobe rating scale: application to Alzheimer's disease and frontotemporal dementia. J Neurol Neurosurg Psychiatry 2001; 70: 165-73.
23. Gaugler JE, Ascher-Svanum H, Roth DL, Fafowora T, Siderowf A, Beach TG. Characteristics of patients misdiagnosed with Alzheimer's disease and their medication use: an analysis of the NACC-UDS database. BMC Geriatr 2013; 13: 137
24. Gorno-Tempini ML, Hillis AE, Weintraub S, Kertesz A, Mendez M, Cappa SF, et al. Classification of primary progressive aphasia and its variants. Neurology 2011; 76: 1006-14.
25. Harper L, Barkhof F, Fox NC, Schott JM. Using visual rating to diagnose dementia: a critical evaluation of MRI atrophy scales. J Neurol Neurosurg Psychiatry 2015; 86: 1225-33.
26. Harper L, Barkhof F, Scheltens P, Schott JM, Fox NC An algorithmic approach to structural imaging in dementia. J Neurol Neurosurg Psychiatry 2014; 85: 692-8.
27. Hornberger M, Savage S, Hsieh S, Mioshi E, Piguet O, Hodges JR. Orbitofrontal dysfunction discriminates behavioral variant frontotemporal dementia from Alzheimer's disease. Dement Geriatr Cogn Disord 2010; 30: 547-52.
28. Hort J, O'Brien JT, Gainotti G, Pirttila T, Popescu BO, Rektorova I, et al. EFNS guidelines for the diagnosis and management of Alzheimer's disease. Eur J Neurol 2010; 17: 1236-48.
29. Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimers Dement J Alzheimers Assoc 2012; 8: 1-13.
30. Jack CR, Barrio JR, Kepe V. Cerebral amyloid PET imaging in Alzheimer's disease. Acta Neuropathol (Berl) 2013; 126: 643-57.
31. Jones E, Oliphant T, Peterson P. et al. SciPy: Open source scientific tools for Python. 2001. http://www.scipy.org/ [Online; accessed 2015-08-31].
32. Kipps CM, Davies RR, Mitchell J, Kril JJ, Halliday GM, Hodges JR. Clinical significance of lobar atrophy in frontotemporal dementia: application of an MRI visual rating scale. Dement Geriatr Cogn Disord 2007; 23: 334-42.
33. Koedam EL, Lehmann M, van der Flier WM, Scheltens P, Pijnenburg YAL, Fox N, et al. Visual assessment of posterior atrophy development of a MRI rating scale. Eur Radiol 2011; 21: 2618-25.
34. Koikkalainen J, Pö lö nen H, Mattila J, van Gils M, Soininen H, Lö tjö nen J Improved classification of Alzheimer's disease data via removal of nuisance variability. PLoS One 2012; 7: e31112
35. Lehmann M, Koedam EL, Barnes J, Bartlett JW, Ryan NS, Pijnenburg YAL, et al. Posterior cerebral atrophy in the absence of medial temporal lobe atrophy in pathologically-confirmed Alzheimer's disease. Neurobiol Aging 2012; 33: 627.e1-.e12.
36. Leung KK, Barnes J, Modat M, Ridgway GR, Bartlett JW, Fox NC, et al. Brain MAPS: an automated, accurate and robust brain extraction technique using a template library. Neuroimage 2011; 55: 1091-108.
37. Likeman M, Anderson VM, Stevens JM, Waldman AD, Godbolt AK, Frost C, et al. Visual assessment of atrophy on magnetic resonance imaging in the diagnosis of pathologically confirmed young-onset dementias. Arch Neurol 2005; 62: 1410-15.
38. Mackenzie IRA, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, et al. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathol (Berl) 2010; 119: 1-4.
39. McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, Feldman H, et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology 2005; 65: 1863-72.
40. McKinney W. Data structures for statistical computing in Python. In: Proceedings of the 9th Python Science Conference, Austin, Texas, 2010, pp. 51-6.
41. Modat M, Ridgway GR, Taylor ZA, Lehmann M, Barnes J, Hawkes DJ, et al. Fast free-form deformation using graphics processing units. Comput Methods Programs Biomed 2010; 98: 278-84.
42. Moller C, van der Flier WM, Versteeg A, Benedictus MR, Wattjes MP, Koedam EL, et al. Quantitative regional validation of the visual rating scale for posterior cortical atrophy. Eur Radiol 2014; 24: 397-404.
43. National Collaborating Centre for Mental Health (UK). Dementia: The NICE-SCIE guideline on supporting people with dementia and their carers in health and social care (National Clinical Practice Guideline) [Internet]. British Psychological Society and RCPsych Publications, 2006.
44. Newcombe RG. Confidence intervals for an effect size measure based on the Mann-Whitney statistic. Part 2: asymptotic methods and evaluation. Stat Med 2006; 25: 559-73.
45. Ourselin S, Roche A, Subsol G, Pennec X, Ayache N. Reconstructing a 3D structure from serial histological sections. Image Vis Comput 2001; 19: 25-31.
46. Pedregosa F, Varoquaux G, Gramfort A, Michel V, Thirion B, Grisel O, et al. Scikit-learn: machine learning in Python. J Mach Learn Res 2011; 12: 2825-30.
47. Rakotomamonjy A. Variable selection using SVM based criteria. J Mach Learn Res 2003; 3: 1357-70.
48. Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain 2011; 134: 2456-77.
49. Ridgway GR, Omar R, Ourselin S, Hill DLG, Warren JD, Fox NC. Issues with threshold masking in voxel-based morphometry of atrophied brains. Neuroimage 2009; 44: 99-111.
50. Rohrer JD, Lashley T, Schott JM, Warren JE, Mead S, Isaacs AM, et al. Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration. Brain 2011; 134: 2565-81.
51. Rossor MN, Fox NC, Mummery CJ, Schott JM, Warren JD. The diagnosis of young-onset dementia. Lancet Neurol 2010; 9: 793-806.
52. Scheltens P, Leys D, Barkhof F, Huglo D, Weinstein HC, Vermersch P, et al. Atrophy of medial temporal lobes on MRI in 'probable' Alzheimer's disease and normal ageing: diagnostic value and neuropsychological correlates. J Neurol Neurosurg Psychiatry 1992; 55: 967-72.
53. Schott JM, Warren JD Alzheimer's disease: mimics and chameleons. Pract Neurol 2012; 12: 358-66.
54. Schrouff J, Rosa MJ, Rondina JM, Marquand AF, Chu C, Ashburner J, et al. PRoNTo: pattern recognition for neuroimaging toolbox. Neuroinformatics 2013; 11: 319-37.
55. Shen Q, Loewenstein DA, Potter E, Zhao W, Appel J, Greig MT, et al. Volumetric and visual rating of magnetic resonance imaging scans in the diagnosis of amnestic mild cognitive impairment and Alzheimer's disease. Alzheimers Dement 2011; 7: e101-8.
56. Shrout PE, Fleiss JL. Intraclass correlations: uses in assessing rater reliability. Psychol. Bull 1979; 86: 420-8.
57. van der Walt S, Colbert SC, Varoquaux G. The NumPy array: a structure for efficient numerical computation. Comput. Sci. Eng 2011; 13: 22-30.
58. Whitwell JL, Jack CR, Parisi JE, Senjem ML, Knopman DS, Boeve BF, et al. Does TDP-43 type confer a distinct pattern of atrophy in frontotemporal lobar degeneration? Neurology 2010; 75: 2212-20.
59. Whitwell JL, Jack CR, Przybelski SA, Parisi JE, Senjem ML, Boeve BF, et al. Temporoparietal atrophy: a marker of AD pathology independent of clinical diagnosis. Neurobiol Aging 2011; 32: 1531-41.