Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells

Bone

Volumn 88, Issue , 2016, Pages 20-30

  Collette, Nicole M ^a   Yee, Cristal S ^a,b   Hum, Nicholas R ^a   Murugesh, Deepa K ^a   Christiansen, Blaine A ^c   Xie, LiQin ^d   Economides, Aris N ^d   Manilay, Jennifer O ^b   Robling, Alexander G ^e   Loots, Gabriela G ^a,b  

^a LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d REGENERON PHARMACEUTICALS INC   (United States)

^e INDIANA UNIVERSITY   (United States)

Author keywords

Bone regeneration; Ectodin; Fracture repair; Periosteum; Sost; Sost like; Sostdc1; Usag 1; Wise; Wnt signaling

Indexed keywords

CELL PROTEIN; SOSTDC1 PROTEIN; UNCLASSIFIED DRUG; ACTIN; ALPHA-SMOOTH MUSCLE ACTIN, MOUSE; BONE MORPHOGENETIC PROTEIN; NESTIN; SOSTDC1 PROTEIN, MOUSE; SP7 PROTEIN, MOUSE; TRANSCRIPTION FACTOR OSTERIX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MASS; BONE METABOLISM; CALLUS; CELL DIFFERENTIATION; CELL EXPANSION; CELL MIGRATION; CELL POPULATION; CONTROLLED STUDY; FRACTURE HEALING; GENE EXPRESSION; LUMBAR VERTEBRA; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; OSTEOBLAST; PERIOSTEUM; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRABECULAR BONE; ANIMAL; BIOMECHANICS; BONE DEVELOPMENT; BONE MINERALIZATION; C57BL MOUSE; CELL PROLIFERATION; CORTICAL BONE; CYTOLOGY; DEFICIENCY; DIAGNOSTIC IMAGING; FEMUR; GENE DELETION; MESENCHYMAL STROMA CELL; METABOLISM; MICRO-COMPUTED TOMOGRAPHY; ORGAN SIZE; PATHOLOGY; STEM CELL; WNT SIGNALING;

ACTINS; ANIMALS; BIOMECHANICAL PHENOMENA; BONE MORPHOGENETIC PROTEINS; BONY CALLUS; CALCIFICATION, PHYSIOLOGIC; CANCELLOUS BONE; CELL DIFFERENTIATION; CELL PROLIFERATION; CORTICAL BONE; FEMUR; FRACTURE HEALING; GENE DELETION; MESENCHYMAL STROMAL CELLS; MICE, INBRED C57BL; NESTIN; ORGAN SIZE; OSTEOBLASTS; OSTEOGENESIS; PERIOSTEUM; PHENOTYPE; SP7 TRANSCRIPTION FACTOR; STEM CELLS; WNT SIGNALING PATHWAY; X-RAY MICROTOMOGRAPHY;

EID: 84964470770     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2016.04.005     Document Type: Article

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