Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice

Nature Medicine

Volumn 22, Issue 5, 2016, Pages 563-567

  Choi, Vivian M ^a   Herrou, Julien ^a   Hecht, Aaron L ^a   Teoh, Wei Ping ^a   Turner, Jerrold R ^a,b   Crosson, Sean ^a   Wardenburg, Juliane Bubeck ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; CYSTEINE PROTEINASE; FRAGILYSIN; FRAGIPAIN; PROTEINASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BACTERIAL TOXIN; METALLOPROTEINASE;

ANAEROBIC INFECTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTEROIDES FRAGILIS; CLOSTRIDIUM; COLITIS; CONTROLLED STUDY; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANAEROBIC BACTERIUM; ANIMAL; BACTEREMIA; BACTEROIDES INFECTION; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; MICROBIOLOGY; SEPSIS; VIRULENCE; WESTERN BLOTTING; X RAY CRYSTALLOGRAPHY;

ANIMALS; BACTEREMIA; BACTERIA, ANAEROBIC; BACTERIAL PROTEINS; BACTERIAL TOXINS; BACTEROIDES FRAGILIS; BACTEROIDES INFECTIONS; BLOTTING, WESTERN; COLITIS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE PROTEASES; FLUORESCENT ANTIBODY TECHNIQUE; METALLOENDOPEPTIDASES; MICE; SEPSIS; VIRULENCE;

EID: 84964388948     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4077     Document Type: Article

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