Supplementation of protein-free diet with whey protein hydrolysates prevents skeletal muscle mass loss in rats

Journal of Nutrition and Intermediary Metabolism

Volumn 4, Issue , 2016, Pages 1-5

  Kobayashi, Yodai ^a   Somoto, Yuuki ^a   Mitsuyama, Eri ^a   Tanaka, Azusa ^a   Yuda, Naoki ^a   Nakada, Hajime ^a   Yamada, Akio ^a   Yamauchi, Koji ^a   Abe, Fumiaki ^a   Nagasawa, Takashi ^b  

^a MORINAGA MILK INDUSTRY CO LTD   (Japan)

^b IWATE UNIVERSITY   (Japan)

Author keywords

Amino acid supplementation; Extensor digitorum longus; Muscle reduction; Protein free diet; Whey protein

Indexed keywords

BRANCHED CHAIN AMINO ACID; ESSENTIAL AMINO ACID; LEUCINE; WHEY PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; DIET SUPPLEMENTATION; EXTENSOR DIGITORUM LONGUS MUSCLE; FOOD INTAKE; MALE; MUSCLE MASS; NONHUMAN; POSTPRANDIAL STATE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN RESTRICTION; RAT; SKELETAL MUSCLE;

EID: 84964336614     PISSN: None     EISSN: 23523859     Source Type: Journal    
DOI: 10.1016/j.jnim.2016.03.001     Document Type: Article

References (30)

1. S.M. Phillips A brief review of critical processes in exercise-induced muscular hypertrophy Sports Med. 44 2014 71 77
2. D.R. Thomas Loss of skeletal muscle mass in aging: examining the relationship of starvation, sarcopenia and cachexia Clin. Nutr. 26 2007 389 399
3. T.J. Doherty Aging and sarcopenia J. Appl. Physiol. 95 2003 1717 1727
4. G. Biolo, K.D. Tipton, S. Klein, and R.R. Wolfe An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein Am. J. Physiol. 273 1997 E122 E129
5. D. Paddon-Jones, M. Sheffield-Moore, X.J. Zhang, E. Volpi, S.E. Wolf, A. Aarsland, A.A. Ferrando, and R.R. Wolfe Amino acid ingestion improves muscle protein synthesis in the young and elderly Am. J. Physiol. Endocrinol. Metab. 286 2004 E321 E328
6. J.C. Anthony, T.G. Anthony, and D.K. Layman Leucine supplementation enhances skeletal muscle recovery in rats following exercise J. Nutr. 129 1999 1102 1106
7. E. Volpi, H. Kobayashi, M. Sheffield-Moore, B. Mittendorfer, and R.R. Wolfe Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults Am. J. Clin. Nutr. 78 2003 250 258
8. S.R. Kimball, L.M. Shantz, R.L. Horetsky, and L.S. Jefferson Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6 J. Biol. Chem. 274 1999 11647 11652
9. F. Yoshizawa Regulation of protein synthesis by branched-chain amino acids in vivo Biochem. Biophys. Res. Commun. 313 2004 417 422
10. I. Rieu, C. Sornet, G. Bayle, J. Prugnaud, C. Pouyet, M. Balage, I. Papet, J. Grizard, and D. Dardevet Leucine-supplemented meal feeding for ten days beneficially affects postprandial muscle protein synthesis in old rats J. Nutr. 133 2003 1198 1205
11. S.J. Crozier, S.R. Kimball, S.W. Emmert, J.C. Anthony, and L.S. Jefferson Oral leucine administration stimulates protein synthesis in rat skeletal muscle J. Nutr. 135 2005 376 382
12. E.H. Herningtyas, Y. Okimura, A.E. Handayaningsih, D. Yamamoto, T. Maki, K. Iida, Y. Takahashi, H. Kaji, and K. Chihara Branched-chain amino acids and arginine suppress MaFbx/atrogin-1 mRNA expression via mTOR pathway in C2C12 cell line Biochim. Biophys. Acta 1780 2008 1115 1120
13. T. Maki, D. Yamamoto, S. Nakanishi, K. Iida, G. Iguchi, Y. Takahashi, H. Kaji, K. Chihara, and Y. Okimura Branched-chain amino acids reduce hindlimb suspension-induced muscle atrophy and protein levels of atrogin-1 and MuRF1 in rats Nutr. Res. 32 2012 676 683
14. T. Sugawara, Y. Ito, N. Nishizawa, and T. Nagasawa Supplementation with dietary leucine to a protein-deficient diet suppresses myofibrillar protein degradation in rats J. Nutr. Sci. Vitaminol. 53 2007 552 555
15. T. Sugawara, Y. Ito, N. Nishizawa, and T. Nagasawa Regulation of muscle protein degradation, not synthesis, by dietary leucine in rats fed a protein-deficient diet Amino Acids 37 2009 609 616
16. R. Kakigi, T. Yoshihara, H. Ozaki, Y. Ogura, N. Ichinoseki-Sekine, H. Kobayashi, and H. Naito Whey protein intake after resistance exercise activates mTOR signaling in a dose-dependent manner in human skeletal muscle Eur. J. Appl. Physiol. 114 2014 735 742
17. Y. Yang, L. Breen, N.A. Burd, A.J. Hector, T.A. Churchward-Venne, A.R. Josse, M.A. Tarnopolsky, and S.M. Phillips Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men Br. J. Nutr. 108 2012 1780 1788
18. Y. Boirie, M. Dangin, P. Gachon, M.P. Vasson, J.L. Maubois, and B. Beaufrère Slow and fast dietary proteins differently modulate postprandial protein accretion Proc. Natl. Acad. Sci. U. S. A. 94 1997 14930 14935
19. B. Pennings, Y. Boirie, J.M. Senden, A.P. Gijsen, H. Kuipers, and L.J. van Loon Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men Am. J. Clin. Nutr. 93 2011 997 1005
20. M. Morifuji, M. Ishizaka, S. Baba, K. Fukuda, H. Matsumoto, J. Koga, M. Kanegae, and M. Higuchi Comparison of different sources and degrees of hydrolysis of dietary protein: effect on plasma amino acids, dipeptides, and insulin responses in human subjects J. Agric. Food Chem. 58 2010 8788 8797
21. A. Kanda, K. Nakayama, T. Fukasawa, J. Koga, M. Kanegae, K. Kawanaka, and M. Higuchi Post-exercise whey protein hydrolysate supplementation induces a greater increase in muscle protein synthesis than its constituent amino acid content Br. J. Nutr. 110 2013 981 987
22. A. Kanda, T. Ishijima, F. Shinozaki, K. Nakayama, T. Fukasawa, Y. Nakai, K. Abe, K. Kawahata, and S. Ikegami Post-exercise impact of ingested whey protein hydrolysate on gene expression profiles in rat skeletal muscle: activation of extracellular signal-regulated kinase 1/2 and hypoxia-inducible factor-1α Br. J. Nutr. 111 2014 2067 2078
23. A. Termin, R.S. Staron, and D. Pette Myosin heavy chain isoforms in histochemically defined fiber types of rat muscle Histochemistry 92 1989 453 457
24. V. Augusto, C.R. Padovani, and G.E.R. Campos Skeletal muscle types in C57BL/J mice Braz. J. Morphol. Sci. 21 2004 89 94
25. M.S. Veldee, and L.D. Peth Can protein-calorie malnutrition cause dysphagia? Dysphagia 7 1992 86 101
26. F. Yoshizawa, H. Sekizawa, S. Hirayama, A. Hatakeyama, T. Nagasawa, and K. Sugahara Time course of leucine-induced 4E-BP1 and S6K1 phosphorylation in the liver and skeletal muscle of rats J. Nutr. Sci. Vitaminol. (Tokyo) 47 2001 311 315
27. R. Koopman, N. Crombach, A.P. Gijsen, S. Walrand, J. Fauquant, A.K. Kies, S. Lemosquet, W.H. Saris, Y. Boirie, and L.J. van Loon Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein Am. J. Clin. Nutr. 90 2009 106 115
28. C.S. Katsanos, H. Kobayashi, M. Sheffield-Moore, A. Aarsland, and R.R. Wolfe A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly Am. J. Physiol. Endocrinol. Metab. 291 2006 381 387
29. M. Morifuji, J. Koga, K. Kawanaka, and M. Higuchi Branched-chain amino acid-containing dipeptides, identified from whey protein hydrolysates, stimulate glucose uptake rate in L6 myotubes and isolated skeletal muscles J. Nutr. Sci. Vitaminol. 55 2009 81 86
30. M. Morifuji, A. Kanda, J. Koga, K. Kawanaka, and M. Higuchi Post-exercise carbohydrate plus whey protein hydrolysates supplementation increases skeletal muscle glycogen level in rats Amino Acids 38 2010 1109 1115