메뉴 건너뛰기




Volumn 11, Issue 6, 2015, Pages 442-449

Breast cancer experience of the molecular tumor board at the University of California, San Diego moores cancer center

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; B RAF KINASE; BRCA2 PROTEIN; CRK LIKE PROTEIN; CYCLIN D1; CYCLIN D2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; FIBROBLAST GROWTH FACTOR 19; FIBROBLAST GROWTH FACTOR 23; FIBROBLAST GROWTH FACTOR 3; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR RECEPTOR 1; K RAS PROTEIN; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE CATALYTIC SUBUNIT ALPHA; PROGESTERONE RECEPTOR; PROTEIN; PROTEIN P53; PROTEIN RET; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG; UNINDEXED DRUG; UVOMORULIN; ZINC FINGER PROTEIN 217;

EID: 84947216680     PISSN: 15547477     EISSN: 1935469X     Source Type: Journal    
DOI: 10.1200/JOP.2015.004127     Document Type: Article
Times cited : (55)

References (26)
  • 2
    • 84900031607 scopus 로고    scopus 로고
    • A targeted next-generation sequencing assay detects a high frequency of therapeutically targetable alterations in primary and metastatic breast cancers: Implications for clinical practice
    • Vasan N, Yelensky R, Wang K., et al: A targeted next-generation sequencing assay detects a high frequency of therapeutically targetable alterations in primary and metastatic breast cancers: Implications for clinical practice. Oncologist 19: 453-458, 2014
    • (2014) Oncologist , vol.19 , pp. 453-458
    • Vasan, N.1    Yelensky, R.2    Wang, K.3
  • 3
    • 84901217741 scopus 로고    scopus 로고
    • Unique molecular signatures as a hallmark of patients with metastatic breast cancer: Implications for current treatment paradigms
    • Wheler JJ, Parker BA, Lee J.J., et al: Unique molecular signatures as a hallmark of patients with metastatic breast cancer: Implications for current treatment paradigms. Oncotarget 5:2349-2354, 2014
    • (2014) Oncotarget , vol.5 , pp. 2349-2354
    • Wheler, J.J.1    Parker, B.A.2    Lee, J.J.3
  • 4
    • 84863983915 scopus 로고    scopus 로고
    • Mutation profiling identifies numerous rare drug targets and distinct mutation patterns in different clinical subtypes of breast cancers
    • Santarpia L, Qi Y, Stemke-Hale K, et al: Mutation profiling identifies numerous rare drug targets and distinct mutation patterns in different clinical subtypes of breast cancers. Breast Cancer Res Treat 134:333-343, 2012
    • (2012) Breast Cancer Res Treat , vol.134 , pp. 333-343
    • Santarpia, L.1    Qi, Y.2    Stemke-Hale, K.3
  • 5
    • 84899479286 scopus 로고    scopus 로고
    • Combined analysis of gene expression, DNA copy number, and mutation profiling data to display biological process Anomalies in individual breast cancers
    • Shi W, Balazs B, Györffy B, et al: Combined analysis of gene expression, DNA copy number, and mutation profiling data to display biological process anomalies in individual breast cancers. Breast Cancer Res Treat 144:561-568, 2014
    • (2014) Breast Cancer Res Treat , vol.144 , pp. 561-568
    • Shi, W.1    Balazs, B.2    Györffy, B.3
  • 6
    • 84918529556 scopus 로고    scopus 로고
    • Unique molecular landscapes in cancer: Implications for individualized, curated drug combinations
    • Wheler J, Lee JJ, Kurzrock R: Unique molecular landscapes in cancer: Implications for individualized, curated drug combinations. Cancer Res 74:7181-7184, 2014
    • (2014) Cancer Res , vol.74 , pp. 7181-7184
    • Wheler, J.1    Lee, J.J.2    Kurzrock, R.3
  • 7
    • 84901918076 scopus 로고    scopus 로고
    • Molecular tumor board: The university of California-San Diego moores cancer center experience
    • Schwaederlé M, Parker BA, Schwab RB, et al: Molecular tumor board: The University of California-San Diego Moores Cancer Center experience. Oncologist 19:631-636, 2014
    • (2014) Oncologist , vol.19 , pp. 631-636
    • Schwaederlé, M.1    Parker, B.A.2    Schwab, R.B.3
  • 8
    • 84947222728 scopus 로고    scopus 로고
    • FoundationOne. http://foundationone.com/
  • 9
    • 0037143750 scopus 로고    scopus 로고
    • High-resolution mapping of the 11q13 amplicon and identification ofa gene, TAOS1, that is amplified and overexpressed in oral cancer cells
    • Huang X, Gollin SM, Raja S, et al: High-resolution mapping of the 11q13 amplicon and identification ofa gene, TAOS1, that is amplified and overexpressed in oral cancer cells. Proc Natl Acad Sci U S A 99:11369-11374, 2002
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 11369-11374
    • Huang, X.1    Gollin, S.M.2    Raja, S.3
  • 10
    • 84923294701 scopus 로고    scopus 로고
    • Cyclin alterations in diverse cancers: Outcome and co-amplification network
    • Schwaederlé M, Daniels GA, Piccioni DE, et al: Cyclin alterations in diverse cancers: Outcome and co-amplification network. Oncotarget 6:3033-3042, 2014
    • (2014) Oncotarget , vol.6 , pp. 3033-3042
    • Schwaederlé, M.1    Daniels, G.A.2    Piccioni, D.E.3
  • 11
    • 84983718691 scopus 로고    scopus 로고
    • Mcl-1-dependent activation of beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells
    • Tai W-T, Shiau C-W, Chen H-L, et al: Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells. Cell Death Dis 4:e485, 2013
    • (2013) Cell Death Dis , vol.4 , pp. e485
    • Tai, W.-T.1    Shiau, C.-W.2    Chen, H.-L.3
  • 12
    • 84862248701 scopus 로고    scopus 로고
    • Dasatinib therapy results in decreased B cell proliferation, splenomegaly, and tumor growthin amurine model of lymphoma expressing myc and Epstein-Barr virus LMP2A
    • Dargart JL, Fish K, Gordon L.I., et al: Dasatinib therapy results in decreased B cell proliferation, splenomegaly, and tumor growthin amurine model of lymphoma expressing Myc and Epstein-Barr virus LMP2A. Antiviral Res 95:49-56, 2012
    • (2012) Antiviral Res , vol.95 , pp. 49-56
    • Dargart, J.L.1    Fish, K.2    Gordon, L.I.3
  • 13
    • 16444379884 scopus 로고    scopus 로고
    • Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma
    • Aguirre D, Boya P, Bellet D., et al: Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma. Apoptosis 9:797-805, 2004
    • (2004) Apoptosis , vol.9 , pp. 797-805
    • Aguirre, D.1    Boya, P.2    Bellet, D.3
  • 14
    • 84863338519 scopus 로고    scopus 로고
    • PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic Malignancies harboring PIK3CA mutations
    • Janku F, Wheler JJ, Westin S.N., et al: PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations. J Clin Oncol 30:777-782, 2012
    • (2012) J Clin Oncol , vol.30 , pp. 777-782
    • Janku, F.1    Wheler, J.J.2    Westin, S.N.3
  • 15
    • 84895906492 scopus 로고    scopus 로고
    • Assessing PIK3CAand PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors
    • Janku F, Hong DS, Fu S, et al: Assessing PIK3CAand PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors. Cell Rep 6:377-387, 2014
    • (2014) Cell Rep , vol.6 , pp. 377-387
    • Janku, F.1    Hong, D.S.2    Fu, S.3
  • 16
    • 84885435345 scopus 로고    scopus 로고
    • Correlation of molecular alterations with efficacy of everolimus in hormone-receptor-positive (HR+), HER2-negative advanced breast cancer: Preliminary results from BOLERO-2
    • Hortobagyi G, Piccart-Gebhart MJ, Rugo H.S., et al: Correlation of molecular alterations with efficacy of everolimus in hormone-receptor-positive (HR+), HER2-negative advanced breast cancer: Preliminary results from BOLERO-2. J Clin Oncol 31:9s, 2013 (suppl; abstr LBA509)
    • (2013) J Clin Oncol , vol.31 , pp. 9s
    • Hortobagyi, G.1    Piccart-Gebhart, M.J.2    Rugo, H.S.3
  • 17
    • 79951906119 scopus 로고    scopus 로고
    • Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments fortheir refractory cancers
    • Von Hoff D.D., Stephenson JJ Jr, Rosen P, et al: Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments fortheir refractory cancers. J Clin Oncol 28:4877-4883, 2010
    • (2010) J Clin Oncol , vol.28 , pp. 4877-4883
    • Von Hoff, D.D.1    Stephenson, J.J.2    Rosen, P.3
  • 18
    • 84888381937 scopus 로고    scopus 로고
    • Activating ESR1 mutations in hormone-resistant metastatic breast cancer
    • Robinson DR, Wu Y-M, Vats P, et al: Activating ESR1 mutations in hormone-resistant metastatic breast cancer. Nat Genet 45:1446-1451, 2013
    • (2013) Nat Genet , vol.45 , pp. 1446-1451
    • Robinson, D.R.1    Wu, Y.-M.2    Vats, P.3
  • 19
    • 0030445855 scopus 로고    scopus 로고
    • Constitutively active human estrogen receptors containing amino acid substitutions fortyrosine 537 in the receptor protein
    • Weis KE, Ekena K, Thomas J.A., et al: Constitutively active human estrogen receptors containing amino acid substitutions fortyrosine 537 in the receptor protein. Mol Endocrinol 10:1388-1398, 1996
    • (1996) Mol Endocrinol , vol.10 , pp. 1388-1398
    • Weis, K.E.1    Ekena, K.2    Thomas, J.A.3
  • 20
    • 84888391516 scopus 로고    scopus 로고
    • ESR1 ligand-binding domain mutations in hormone-resistant breast cancer
    • Toy W, Shen Y, Won H., et al: ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nat Genet 45:1439-1445, 2013
    • (2013) Nat Genet , vol.45 , pp. 1439-1445
    • Toy, W.1    Shen, Y.2    Won, H.3
  • 21
    • 80051558985 scopus 로고    scopus 로고
    • High-resolution genomic analysis of the 11q13 amplicon in breast cancers identifies synergy with 8p12 amplification, involving the mTOR targets S6K2 and 4EBP1
    • Karlsson E, Waltersson MA, Bostner J, et al: High-resolution genomic analysis of the 11q13 amplicon in breast cancers identifies synergy with 8p12 amplification, involving the mTOR targets S6K2 and 4EBP1. Genes Chromosomes Cancer 50:775-787, 2011
    • (2011) Genes Chromosomes Cancer , vol.50 , pp. 775-787
    • Karlsson, E.1    Waltersson, M.A.2    Bostner, J.3
  • 22
    • 84925408760 scopus 로고    scopus 로고
    • Phase I/IIa study evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of lucitanib in advanced solid tumors
    • Soria J-C, De Braud F, Bahleda R, et al: Phase I/IIa study evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of lucitanib in advanced solid tumors. Ann Oncol 25:2244-2251, 2014
    • (2014) Ann Oncol , vol.25 , pp. 2244-2251
    • Soria, J.-C.1    De Braud, F.2    Bahleda, R.3
  • 23
    • 84902576450 scopus 로고    scopus 로고
    • Conflicted confidence: Academic oncologists' views on multiplex pharmacogenomic testing
    • Hall MJ: Conflicted confidence: academic oncologists' views on multiplex pharmacogenomic testing. J Clin Oncol 32:1290-1292, 2014
    • (2014) J Clin Oncol , vol.32 , pp. 1290-1292
    • Hall, M.J.1
  • 24
    • 84902583099 scopus 로고    scopus 로고
    • Physicians' attitudes about multiplex tumor genomic testing
    • Gray SW, Hicks-Courant K, Cronin A., et al: Physicians' attitudes about multiplex tumor genomic testing. J Clin Oncol 32:1317-1323, 2014
    • (2014) J Clin Oncol , vol.32 , pp. 1317-1323
    • Gray, S.W.1    Hicks-Courant, K.2    Cronin, A.3
  • 25
    • 84875752240 scopus 로고    scopus 로고
    • Emerging targeted agents in metastatic breast cancer
    • Zardavas D, Baselga J, Piccart M: Emerging targeted agents in metastatic breast cancer. Nat Rev Clin Oncol 10:191-210, 2013
    • (2013) Nat Rev Clin Oncol , vol.10 , pp. 191-210
    • Zardavas, D.1    Baselga, J.2    Piccart, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.