메뉴 건너뛰기




Volumn 25, Issue 10, 2014, Pages 2008-2014

Clinicopathologic characteristics and gene expression analyses of non-KRAS 12/13, RAS-mutated metastatic colorectal cancer

Author keywords

colorectal cancer; gene expression; KRAS; next generation sequencing; survival

Indexed keywords

B RAF KINASE; BRAF PROTEIN, HUMAN; CODON; KRAS PROTEIN, HUMAN; ONCOPROTEIN; RAS PROTEIN;

EID: 84964314170     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdu252     Document Type: Article
Times cited : (44)

References (16)
  • 2
    • 0032490124 scopus 로고    scopus 로고
    • Kirsten ras mutations in patients with colorectal cancer: the multicenter ‘RASCAL’ study
    • Andreyev, H.J., Norman, A.R., Cunningham, D., et al. Kirsten ras mutations in patients with colorectal cancer: the multicenter ‘RASCAL’ study. J Natl Cancer Inst 90 (1998), 675–684.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 675-684
    • Andreyev, H.J.1    Norman, A.R.2    Cunningham, D.3
  • 4
    • 0030772378 scopus 로고    scopus 로고
    • The Ras–RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants
    • Scheffzek, K., Ahmadian, M.R., Kabsch, W., et al. The Ras–RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science 277 (1997), 333–338.
    • (1997) Science , vol.277 , pp. 333-338
    • Scheffzek, K.1    Ahmadian, M.R.2    Kabsch, W.3
  • 5
    • 0023619575 scopus 로고
    • A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants
    • Trahey, M., McCormick, F., A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants. Science 238 (1987), 542–545.
    • (1987) Science , vol.238 , pp. 542-545
    • Trahey, M.1    McCormick, F.2
  • 6
    • 54949085398 scopus 로고    scopus 로고
    • K-ras mutations and benefit from cetuximab in advanced colorectal cancer
    • Karapetis, C.S., Khambata-Ford, S., Jonker, D.J., et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 359 (2008), 1757–1765.
    • (2008) N Engl J Med , vol.359 , pp. 1757-1765
    • Karapetis, C.S.1    Khambata-Ford, S.2    Jonker, D.J.3
  • 7
    • 59749091477 scopus 로고    scopus 로고
    • Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
    • Tol, J., Koopman, M., Cats, A., et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med 360 (2009), 563–572.
    • (2009) N Engl J Med , vol.360 , pp. 563-572
    • Tol, J.1    Koopman, M.2    Cats, A.3
  • 8
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • Van Cutsem, E., Kohne, C.H., Hitre, E., et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 360 (2009), 1408–1417.
    • (2009) N Engl J Med , vol.360 , pp. 1408-1417
    • Van Cutsem, E.1    Kohne, C.H.2    Hitre, E.3
  • 9
    • 84883680951 scopus 로고    scopus 로고
    • Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer
    • Douillard, J.Y., Oliner, K.S., Siena, S., et al. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med 369 (2013), 1023–1034.
    • (2013) N Engl J Med , vol.369 , pp. 1023-1034
    • Douillard, J.Y.1    Oliner, K.S.2    Siena, S.3
  • 10
    • 84969973405 scopus 로고    scopus 로고
    • Analysis of KRAS/NRAS mutations in the phase 3 20050181 study of panitubumab + FOLFIRI versus FOLFIRI as second-line treatment for metastatic colorectal cancer
    • Peeters, M., Oliner, K., Price, T., Cervantes, A., Analysis of KRAS/NRAS mutations in the phase 3 20050181 study of panitubumab + FOLFIRI versus FOLFIRI as second-line treatment for metastatic colorectal cancer. J Clin Oncol, 32(Suppl. 3), 2014, LBA387.
    • (2014) J Clin Oncol , vol.32 , pp. LBA387
    • Peeters, M.1    Oliner, K.2    Price, T.3    Cervantes, A.4
  • 11
    • 0022471217 scopus 로고
    • Biological and biochemical properties of human rasH genes mutated at codon 61
    • Der, C.J., Finkel, T., Cooper, G.M., Biological and biochemical properties of human rasH genes mutated at codon 61. Cell 44 (1986), 167–176.
    • (1986) Cell , vol.44 , pp. 167-176
    • Der, C.J.1    Finkel, T.2    Cooper, G.M.3
  • 12
    • 84856579570 scopus 로고    scopus 로고
    • Integrated annotation and analysis of genetic variants from next-generation sequencing studies with variant tools
    • San Lucas, F.A., Wang, G., Scheet, P., Peng, B., Integrated annotation and analysis of genetic variants from next-generation sequencing studies with variant tools. Bioinformatics 28 (2012), 421–422.
    • (2012) Bioinformatics , vol.28 , pp. 421-422
    • San Lucas, F.A.1    Wang, G.2    Scheet, P.3    Peng, B.4
  • 13
    • 84882959674 scopus 로고    scopus 로고
    • FOLFIRI plus cetuximab bersus FOLFIRI plus bevacizumab as first-line treatment of KRAS-wildtype metastatic colorectal cancer: German AIO study KRK-0306 (FIRE-3)
    • Modest, D., Welkersthal, L.V., Stintzing, S., et al. FOLFIRI plus cetuximab bersus FOLFIRI plus bevacizumab as first-line treatment of KRAS-wildtype metastatic colorectal cancer: German AIO study KRK-0306 (FIRE-3). Ann Oncol 24 (2013), iv11–iv24.
    • (2013) Ann Oncol , vol.24 , pp. iv11-iv24
    • Modest, D.1    Welkersthal, L.V.2    Stintzing, S.3
  • 14
    • 84865744415 scopus 로고    scopus 로고
    • Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers
    • Imamura, Y., Morikawa, T., Liao, X., et al. Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers. Clin Cancer Res 18 (2012), 4753–4763.
    • (2012) Clin Cancer Res , vol.18 , pp. 4753-4763
    • Imamura, Y.1    Morikawa, T.2    Liao, X.3
  • 15
    • 84864659128 scopus 로고    scopus 로고
    • Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer
    • Kim, M.J., Lee, H.S., Kim, J.H., et al. Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer. BMC Cancer, 12, 2012, 347.
    • (2012) BMC Cancer , vol.12 , pp. 347
    • Kim, M.J.1    Lee, H.S.2    Kim, J.H.3
  • 16
    • 84867117207 scopus 로고    scopus 로고
    • Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with first-line chemotherapy with or without cetuximab
    • Tejpar, S., Celik, I., Schlichting, M., et al. Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with first-line chemotherapy with or without cetuximab. J Clin Oncol 30 (2012), 3570–3577.
    • (2012) J Clin Oncol , vol.30 , pp. 3570-3577
    • Tejpar, S.1    Celik, I.2    Schlichting, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.