메뉴 건너뛰기




Volumn 4, Issue OCT, 2014, Pages

An evolving perspective on the Pseudomonas aeruginosa orphan quorum sensing regulator QscR

Author keywords

Acylhomoserine lactone; Bacterial communication; Cell cell signaling; Gene activation; Sociomicrobiology

Indexed keywords

N ACYLHOMOSERINE LACTONE; TRANSCRIPTION FACTOR LUXR; BACTERIAL PROTEIN; GAMMA BUTYROLACTONE DERIVATIVE; LUXI PROTEIN, BACTERIA; LUXR AUTOINDUCER BINDING PROTEINS; PROTEIN BINDING; QSCR PROTEIN, PSEUDOMONAS AERUGINOSA; REPRESSOR PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

EID: 84964312894     PISSN: None     EISSN: 22352988     Source Type: Journal    
DOI: 10.3389/fcimb.2014.00152     Document Type: Review
Times cited : (45)

References (40)
  • 1
    • 34250357654 scopus 로고    scopus 로고
    • Molecular insights into quorum sensing in the human pathogen Pseudomonas aeruginosa from the structure of the virulence regulator LasR bound to its autoinducer
    • Bottomley, M. J., Muraglia, E., Bazzo, R., and Carfi, A. (2007). Molecular insights into quorum sensing in the human pathogen Pseudomonas aeruginosa from the structure of the virulence regulator LasR bound to its autoinducer. J. Biol. Chem. 282, 13592-13600. doi: 10.1074/jbc.M700556200
    • (2007) J. Biol. Chem , vol.282 , pp. 13592-13600
    • Bottomley, M.J.1    Muraglia, E.2    Bazzo, R.3    Carfi, A.4
  • 2
    • 0028849833 scopus 로고
    • Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family
    • Brint, J. M., and Ohman, D. E. (1995). Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family. J. Bacteriol. 177, 7155-7163.
    • (1995) J. Bacteriol , vol.177 , pp. 7155-7163
    • Brint, J.M.1    Ohman, D.E.2
  • 4
    • 0035956915 scopus 로고    scopus 로고
    • QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa
    • Chugani, S. A., Whiteley, M., Lee, K. M., D'Argenio, D., Manoil, C., and Greenberg, E. P. (2001). QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. U.S.A. 98, 2752-2757. doi: 10.1073/pnas.051624298
    • (2001) Proc. Natl. Acad. Sci. U.S.A , vol.98 , pp. 2752-2757
    • Chugani, S.A.1    Whiteley, M.2    Lee, K.M.3    D'Argenio, D.4    Manoil, C.5    Greenberg, E.P.6
  • 5
    • 1642588338 scopus 로고    scopus 로고
    • The role of regulators in the expression of quorum-sensing signals in Pseudomonas aeruginosa
    • Fagerlind, M. G., Rice, S. A., Nilsson, P., Harlen, M., James, S., Charlton, T., et al. (2003). The role of regulators in the expression of quorum-sensing signals in Pseudomonas aeruginosa. J. Mol. Microbiol. Biotechnol. 6, 88-100. doi: 10.1159/000076739
    • (2003) J. Mol. Microbiol. Biotechnol , vol.6 , pp. 88-100
    • Fagerlind, M.G.1    Rice, S.A.2    Nilsson, P.3    Harlen, M.4    James, S.5    Charlton, T.6
  • 6
    • 0029818809 scopus 로고    scopus 로고
    • Census and consensus in bacterial ecosystems: the LuxR-LuxI family of quorum-sensing transcriptional regulators
    • Fuqua, C., Winans, S. C., and Greenberg, E. P. (1996). Census and consensus in bacterial ecosystems: the LuxR-LuxI family of quorum-sensing transcriptional regulators. Annu. Rev. Microbiol. 50, 727-751. doi: 10.1146/annurev.micro.50.1.727
    • (1996) Annu. Rev. Microbiol , vol.50 , pp. 727-751
    • Fuqua, C.1    Winans, S.C.2    Greenberg, E.P.3
  • 7
    • 0041989633 scopus 로고    scopus 로고
    • Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors
    • Hentzer, M., Wu, H., Andersen, J. B., Riedel, K., Rasmussen, T. B., Bagge, N., et al. (2003). Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J. 22, 3803-3815. doi: 10.1093/emboj/cdg366
    • (2003) EMBO J , vol.22 , pp. 3803-3815
    • Hentzer, M.1    Wu, H.2    Andersen, J.B.3    Riedel, K.4    Rasmussen, T.B.5    Bagge, N.6
  • 8
    • 0029831296 scopus 로고    scopus 로고
    • A hierarchical quorum-sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary-phase sigma factor RpoS
    • Latifi, A., Foglino, M., Tanaka, K., Williams, P., and Lazdunski, A. (1996). A hierarchical quorum-sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary-phase sigma factor RpoS. Mol. Microbiol. 21, 1137-1146. doi: 10.1046/j.1365-2958.1996.00063.x
    • (1996) Mol. Microbiol , vol.21 , pp. 1137-1146
    • Latifi, A.1    Foglino, M.2    Tanaka, K.3    Williams, P.4    Lazdunski, A.5
  • 9
    • 0037385875 scopus 로고    scopus 로고
    • Interactions of the quorum sensing regulator QscR: interaction with itself and the other regulators of Pseudomonas aeruginosa LasR and RhlR
    • Ledgham, F., Ventre, I., Soscia, C., Foglino, M., Sturgis, J. N., and Lazdunski, A. (2003). Interactions of the quorum sensing regulator QscR: interaction with itself and the other regulators of Pseudomonas aeruginosa LasR and RhlR. Mol. Microbiol. 48, 199-210. doi: 10.1046/j.1365-2958.2003.03423.x
    • (2003) Mol. Microbiol , vol.48 , pp. 199-210
    • Ledgham, F.1    Ventre, I.2    Soscia, C.3    Foglino, M.4    Sturgis, J.N.5    Lazdunski, A.6
  • 10
    • 33645046114 scopus 로고    scopus 로고
    • Activity of purified QscR, a Pseudomonas aeruginosa orphan quorum-sensing transcription factor
    • Lee, J. H., Lequette, Y., and Greenberg, E. P. (2006). Activity of purified QscR, a Pseudomonas aeruginosa orphan quorum-sensing transcription factor. Mol. Microbiol. 59, 602-609. doi: 10.1111/j.1365-2958.2005.04960.x
    • (2006) Mol. Microbiol , vol.59 , pp. 602-609
    • Lee, J.H.1    Lequette, Y.2    Greenberg, E.P.3
  • 11
    • 3142564584 scopus 로고    scopus 로고
    • The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae
    • Lenz, D. H., Mok, K. C., Lilley, B. N., Kulkarni, R. V., Wingreen, N. S., and Bassler, B. L. (2004). The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae. Cell 118, 69-82. doi: 10.1016/j.cell.2004.06.009
    • (2004) Cell , vol.118 , pp. 69-82
    • Lenz, D.H.1    Mok, K.C.2    Lilley, B.N.3    Kulkarni, R.V.4    Wingreen, N.S.5    Bassler, B.L.6
  • 12
    • 33646232999 scopus 로고    scopus 로고
    • A distinct QscR regulon in the Pseudomonas aeruginosa quorum-sensing circuit
    • Lequette, Y., Lee, J. H., Ledgham, F., Lazdunski, A., and Greenberg, E. P. (2006). A distinct QscR regulon in the Pseudomonas aeruginosa quorum-sensing circuit. J. Bacteriol. 188, 3365-3370. doi: 10.1128/JB.188.9.3365-3370.2006
    • (2006) J. Bacteriol , vol.188 , pp. 3365-3370
    • Lequette, Y.1    Lee, J.H.2    Ledgham, F.3    Lazdunski, A.4    Greenberg, E.P.5
  • 13
    • 84864006267 scopus 로고    scopus 로고
    • The Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression
    • Liang, H., Deng, X., Ji, Q., Sun, F., Shen, T., and He, C. (2012). The Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression. J. Bacteriol. 194, 3098-3108. doi: 10.1128/JB.06679-11
    • (2012) J. Bacteriol , vol.194 , pp. 3098-3108
    • Liang, H.1    Deng, X.2    Ji, Q.3    Sun, F.4    Shen, T.5    He, C.6
  • 14
    • 80053149507 scopus 로고    scopus 로고
    • Crystal structure of QscR, a Pseudomonas aeruginosa quorum sensing signal receptor
    • Lintz, M. J., Oinuma, K., Wysoczynski, C. L., Greenberg, E. P., and Churchill, M. E. (2011). Crystal structure of QscR, a Pseudomonas aeruginosa quorum sensing signal receptor. Proc. Natl. Acad. Sci. U.S.A. 108, 15763-15768. doi: 10.1073/pnas.1112398108
    • (2011) Proc. Natl. Acad. Sci. U.S.A , vol.108 , pp. 15763-15768
    • Lintz, M.J.1    Oinuma, K.2    Wysoczynski, C.L.3    Greenberg, E.P.4    Churchill, M.E.5
  • 15
    • 77951546403 scopus 로고    scopus 로고
    • Inhibitors of the Pseudomonas aeruginosa quorum-sensing regulator, QscR
    • Liu, H. B., Lee, J. H., Kim, J. S., and Park, S. (2010). Inhibitors of the Pseudomonas aeruginosa quorum-sensing regulator, QscR. Biotechnol. Bioeng. 106, 119-126. doi: 10.1002/bit.22672
    • (2010) Biotechnol. Bioeng , vol.106 , pp. 119-126
    • Liu, H.B.1    Lee, J.H.2    Kim, J.S.3    Park, S.4
  • 16
    • 79953715147 scopus 로고    scopus 로고
    • Potent and selective synthetic modulators of a quorum sensing repressor in Pseudomonas aeruginosa identified from second-generation libraries of N-acylated L-homoserine lactones
    • Mattmann, M. E., Shipway, P. M., Heth, N. J., and Blackwell, H. E. (2011). Potent and selective synthetic modulators of a quorum sensing repressor in Pseudomonas aeruginosa identified from second-generation libraries of N-acylated L-homoserine lactones. Chembiochem 12, 942-949. doi: 10.1002/cbic.201000708
    • (2011) Chembiochem , vol.12 , pp. 942-949
    • Mattmann, M.E.1    Shipway, P.M.2    Heth, N.J.3    Blackwell, H.E.4
  • 17
    • 0034770056 scopus 로고    scopus 로고
    • Quorum sensing in bacteria
    • Miller, M. B., and Bassler, B. L. (2001). Quorum sensing in bacteria. Annu. Rev. Microbiol. 55, 165-199. doi: 10.1146/annurev.micro.55.1.165
    • (2001) Annu. Rev. Microbiol , vol.55 , pp. 165-199
    • Miller, M.B.1    Bassler, B.L.2
  • 18
    • 0028349371 scopus 로고
    • Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa
    • Ochsner, U. A., Koch, A. K., Fiechter, A., and Reiser, J. (1994). Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa. J. Bacteriol. 176, 2044-2054.
    • (1994) J. Bacteriol , vol.176 , pp. 2044-2054
    • Ochsner, U.A.1    Koch, A.K.2    Fiechter, A.3    Reiser, J.4
  • 19
    • 0029023052 scopus 로고
    • Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa
    • Ochsner, U. A., and Reiser, J. (1995). Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. U.S.A. 92, 6424-6428. doi: 10.1073/pnas.92.14.6424
    • (1995) Proc. Natl. Acad. Sci. U.S.A , vol.92 , pp. 6424-6428
    • Ochsner, U.A.1    Reiser, J.2
  • 20
    • 78650858840 scopus 로고    scopus 로고
    • Acyl-homoserine lactone binding to and stability of the orphan Pseudomonas aeruginosa quorum-sensing signal receptor QscR
    • Oinuma, K., and Greenberg, E. P. (2011). Acyl-homoserine lactone binding to and stability of the orphan Pseudomonas aeruginosa quorum-sensing signal receptor QscR. J. Bacteriol. 193, 421-428. doi: 10.1128/JB.01041-10
    • (2011) J. Bacteriol , vol.193 , pp. 421-428
    • Oinuma, K.1    Greenberg, E.P.2
  • 21
    • 0027299747 scopus 로고
    • Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication
    • Passador, L., Cook, J. M., Gambello, M. J., Rust, L., and Iglewski, B. H. (1993). Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication. Science 260, 1127-1130. doi: 10.1126/science.8493556
    • (1993) Science , vol.260 , pp. 1127-1130
    • Passador, L.1    Cook, J.M.2    Gambello, M.J.3    Rust, L.4    Iglewski, B.H.5
  • 22
    • 0028012702 scopus 로고
    • Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes
    • Pearson, J. P., Gray, K. M., Passador, L., Tucker, K. D., Eberhard, A., Iglewski, B. H., et al. (1994). Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. Proc. Natl. Acad. Sci. U.S.A. 91, 197-201. doi: 10.1073/pnas.91.1.197
    • (1994) Proc. Natl. Acad. Sci. U.S.A , vol.91 , pp. 197-201
    • Pearson, J.P.1    Gray, K.M.2    Passador, L.3    Tucker, K.D.4    Eberhard, A.5    Iglewski, B.H.6
  • 23
    • 0028953276 scopus 로고
    • A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa
    • Pearson, J. P., Passador, L., Iglewski, B. H., and Greenberg, E. P. (1995). A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. U.S.A. 92, 1490-1494. doi: 10.1073/pnas.92.5.1490
    • (1995) Proc. Natl. Acad. Sci. U.S.A , vol.92 , pp. 1490-1494
    • Pearson, J.P.1    Passador, L.2    Iglewski, B.H.3    Greenberg, E.P.4
  • 24
    • 0030985995 scopus 로고    scopus 로고
    • Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa
    • Pesci, E. C., Pearson, J. P., Seed, P. C., and Iglewski, B. H. (1997). Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa. J. Bacteriol. 179, 3127-3132.
    • (1997) J. Bacteriol , vol.179 , pp. 3127-3132
    • Pesci, E.C.1    Pearson, J.P.2    Seed, P.C.3    Iglewski, B.H.4
  • 25
    • 0037378570 scopus 로고    scopus 로고
    • Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis
    • Schuster, M., Lostroh, C. P., Ogi, T., and Greenberg, E. P. (2003). Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J. Bacteriol. 185, 2066-2079. doi: 10.1128/JB.185.7.2066-2079.2003
    • (2003) J. Bacteriol , vol.185 , pp. 2066-2079
    • Schuster, M.1    Lostroh, C.P.2    Ogi, T.3    Greenberg, E.P.4
  • 26
    • 8644231700 scopus 로고    scopus 로고
    • Promoter specificity in Pseudomonas aeruginosa quorum sensing revealed by DNA binding of purified LasR
    • Schuster, M., Urbanowski, M. L., and Greenberg, E. P. (2004). Promoter specificity in Pseudomonas aeruginosa quorum sensing revealed by DNA binding of purified LasR. Proc. Natl. Acad. Sci. U.S.A. 101, 15833-15839. doi: 10.1073/pnas.0407229101
    • (2004) Proc. Natl. Acad. Sci. U.S.A , vol.101 , pp. 15833-15839
    • Schuster, M.1    Urbanowski, M.L.2    Greenberg, E.P.3
  • 27
    • 0034739007 scopus 로고    scopus 로고
    • Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen
    • Stover, C. K., Pham, X. Q., Erwin, A. L., Mizoguchi, S. D., Warrener, P., Hickey, M. J., et al. (2000). Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature 406, 959-964. doi: 10.1038/35023079
    • (2000) Nature , vol.406 , pp. 959-964
    • Stover, C.K.1    Pham, X.Q.2    Erwin, A.L.3    Mizoguchi, S.D.4    Warrener, P.5    Hickey, M.J.6
  • 28
    • 33846508567 scopus 로고    scopus 로고
    • Multiple small RNAs act additively to integrate sensory information and control quorum sensing in Vibrio harveyi
    • Tu, K. C., and Bassler, B. L. (2007). Multiple small RNAs act additively to integrate sensory information and control quorum sensing in Vibrio harveyi. Genes Dev. 21, 221-233. doi: 10.1101/gad.1502407
    • (2007) Genes Dev , vol.21 , pp. 221-233
    • Tu, K.C.1    Bassler, B.L.2
  • 29
    • 1642581508 scopus 로고    scopus 로고
    • Reversible acyl-homoserine lactone binding to purified Vibrio fischeri LuxR protein
    • Urbanowski, M. L., Lostroh, C. P., and Greenberg, E. P. (2004). Reversible acyl-homoserine lactone binding to purified Vibrio fischeri LuxR protein. J. Bacteriol. 186, 631-637. doi: 10.1128/JB.186.3.631-637.2004
    • (2004) J. Bacteriol , vol.186 , pp. 631-637
    • Urbanowski, M.L.1    Lostroh, C.P.2    Greenberg, E.P.3
  • 30
    • 0031729127 scopus 로고    scopus 로고
    • Cell-to-cell signaling and Pseudomonas aeruginosa infections
    • Van Delden, C., and Iglewski, B. H. (1998). Cell-to-cell signaling and Pseudomonas aeruginosa infections. Emerging Infect. Dis. 4, 551-560. doi: 10.3201/eid0404.980405
    • (1998) Emerging Infect. Dis , vol.4 , pp. 551-560
    • Van Delden, C.1    Iglewski, B.H.2
  • 31
    • 0037009372 scopus 로고    scopus 로고
    • The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA
    • Vannini, A., Volpari, C., Gargioli, C., Muraglia, E., Cortese, R., De Francesco, R., et al. (2002). The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA. EMBO J. 21, 4393-4401. doi: 10.1093/emboj/cdf459
    • (2002) EMBO J , vol.21 , pp. 4393-4401
    • Vannini, A.1    Volpari, C.2    Gargioli, C.3    Muraglia, E.4    Cortese, R.5    De Francesco, R.6
  • 32
    • 2942750479 scopus 로고    scopus 로고
    • Modeling the quorum sensing regulatory network of human-pathogenic Pseudomonas aeruginosa
    • Viretta, A. U., and Fussenegger, M. (2004). Modeling the quorum sensing regulatory network of human-pathogenic Pseudomonas aeruginosa. Biotechnol. Prog. 20, 670-678. doi: 10.1021/bp034323l
    • (2004) Biotechnol. Prog , vol.20 , pp. 670-678
    • Viretta, A.U.1    Fussenegger, M.2
  • 33
    • 0037377827 scopus 로고    scopus 로고
    • Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment
    • Wagner, V. E., Bushnell, D., Passador, L., Brooks, A. I., and Iglewski, B. H. (2003). Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment. J. Bacteriol. 185, 2080-2095. doi: 10.1128/JB.185.7.2080-2095.2003
    • (2003) J. Bacteriol , vol.185 , pp. 2080-2095
    • Wagner, V.E.1    Bushnell, D.2    Passador, L.3    Brooks, A.I.4    Iglewski, B.H.5
  • 35
    • 84907818880 scopus 로고    scopus 로고
    • A new synthetic ligand that activates QscR and blocks antibiotic-tolerant biofilm formation in Pseudomonas aeruginosa
    • Weng, L. X., Yang, Y. X., Zhang, Y. Q., and Wang, L. H. (2014). A new synthetic ligand that activates QscR and blocks antibiotic-tolerant biofilm formation in Pseudomonas aeruginosa. Appl. Microbiol. Biotechnol. 98, 2565-2572. doi: 10.1007/s00253-013-5420-x
    • (2014) Appl. Microbiol. Biotechnol , vol.98 , pp. 2565-2572
    • Weng, L.X.1    Yang, Y.X.2    Zhang, Y.Q.3    Wang, L.H.4
  • 36
    • 28844493693 scopus 로고    scopus 로고
    • Structure of the Escherichia coli quorum sensing protein SdiA: activation of the folding switch by acyl homoserine lactones
    • Yao, Y., Martinez-Yamout, M. A., Dickerson, T. J., Brogan, A. P., Wright, P. E., and Dyson, H. J. (2006). Structure of the Escherichia coli quorum sensing protein SdiA: activation of the folding switch by acyl homoserine lactones. J. Mol. Biol. 355, 262-273. doi: 10.1016/j.jmb.2005.10.041
    • (2006) J. Mol. Biol , vol.355 , pp. 262-273
    • Yao, Y.1    Martinez-Yamout, M.A.2    Dickerson, T.J.3    Brogan, A.P.4    Wright, P.E.5    Dyson, H.J.6
  • 37
    • 0037182879 scopus 로고    scopus 로고
    • Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
    • Zhang, R. G., Pappas, K. M., Brace, J. L., Miller, P. C., Oulmassov, T., Molyneaux, J. M., et al. (2002). Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA. Nature 417, 971-974. doi: 10.1038/nature00833
    • (2002) Nature , vol.417 , pp. 971-974
    • Zhang, R.G.1    Pappas, K.M.2    Brace, J.L.3    Miller, P.C.4    Oulmassov, T.5    Molyneaux, J.M.6
  • 38
    • 0033609151 scopus 로고    scopus 로고
    • Autoinducer binding by the quorum-sensing regulator TraR increases affinity for target promoters in vitro and decreases TraR turnover rates in whole cells
    • Zhu, J., and Winans, S. C. (1999). Autoinducer binding by the quorum-sensing regulator TraR increases affinity for target promoters in vitro and decreases TraR turnover rates in whole cells. Proc. Natl. Acad. Sci. U.S.A. 96, 4832-4837. doi: 10.1073/pnas.96.9.4832
    • (1999) Proc. Natl. Acad. Sci. U.S.A , vol.96 , pp. 4832-4837
    • Zhu, J.1    Winans, S.C.2
  • 39
    • 0035852714 scopus 로고    scopus 로고
    • The quorum-sensing transcriptional regulator TraR requires its cognate signaling ligand for protein folding, protease resistance, and dimerization
    • Zhu, J., and Winans, S. C. (2001). The quorum-sensing transcriptional regulator TraR requires its cognate signaling ligand for protein folding, protease resistance, and dimerization. Proc. Natl. Acad. Sci. U.S.A. 98, 1507-1512. doi: 10.1073/pnas.98.4.1507
    • (2001) Proc. Natl. Acad. Sci. U.S.A , vol.98 , pp. 1507-1512
    • Zhu, J.1    Winans, S.C.2
  • 40
    • 70349182304 scopus 로고    scopus 로고
    • Molecular basis for the recognition of structurally distinct autoinducer mimics by the Pseudomonas aeruginosa LasR quorum-sensing signaling receptor
    • Zou, Y., and Nair, S. K. (2009). Molecular basis for the recognition of structurally distinct autoinducer mimics by the Pseudomonas aeruginosa LasR quorum-sensing signaling receptor. Chem. Biol. 16, 961-970. doi: 10.1016/j.chembiol.2009.09.001
    • (2009) Chem. Biol , vol.16 , pp. 961-970
    • Zou, Y.1    Nair, S.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.