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Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 4, 2015, Pages 864-868

The cryptophycins as potent payloads for antibody drug conjugates

(9) Verma, Vishal A a Pillow, Thomas H a Depalatis, Laura a Li, Guangmin a Phillips, Gail Lewis a Polson, Andrew G a Raab, Helga E a Spencer, Susan a Zheng, Bing a

a GENENTECH INC (United States)

Author keywords

Antibody drug conjugate; Cryptophycin

Indexed keywords

ANTIBODY CONJUGATE; BRENTUXIMAB VEDOTIN; CRYPTOPHYCIN DERIVATIVE; CYTOTOXIC AGENT; MAYTANSINE; TRASTUZUMAB EMTANSINE;

ACYLATION; ANTIBODY DRUG CONJUGATE; ARTICLE; CANCER CELL LINE; CELL ACTIVITY; CONTROLLED STUDY; DRUG CONJUGATION; DRUG ISOLATION; DRUG RELEASE; DRUG SYNTHESIS; IC50; LYSOSOME; MICHAEL ADDITION; PROTEIN DEGRADATION; REVERSE MICHAEL REACTION;

EID: 84964306123 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2014.12.070 Document Type: Article

Times cited : (50)

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