Conjugates of modified cryptophycins and RGD-peptides enter target cells by endocytosis

Journal of Medicinal Chemistry

Volumn 56, Issue 5, 2013, Pages 1853-1864

  Nahrwold, Markus ^a   Weiß, Christine ^a   Bogner, Tobias ^a   Mertink, Felix ^a   Conradi, Jens ^a   Sammet, Benedikt ^a   Palmisano, Ralf ^b   Royo Gracia, Soledad ^a   Preuße, Thomas ^a   Sewald, Norbert ^a  

^a BIELEFELD UNIVERSITY   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ARGINYLGLYCYLASPARTIC ACID; BETA AMINO ACID; CRYPTOPHYCIN 1; CRYPTOPHYCIN 52; CRYPTOPHYCIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELLULAR DISTRIBUTION; CONFORMATION; CYTOTOXICITY TEST; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; DRUG TARGETING; ENDOCYTOSIS; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE; TARGET CELL;

CELL LINE, TUMOR; DEPSIPEPTIDES; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENDOCYTOSIS; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MICROSCOPY, CONFOCAL; MOLECULAR DYNAMICS SIMULATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOPEPTIDES; PROTEIN CONFORMATION;

EID: 84875140978     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301346z     Document Type: Article

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