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Volumn 16, Issue 14, 2016, Pages 1582-1586

Phenotyping and endotyping asthma based on biomarkers

Author keywords

Asthma; Biomarkers; Endotypes; Phenotypes; Response; Treatment

Indexed keywords

BIOLOGICAL MARKER; CORTICOSTEROID; IMMUNOGLOBULIN E; INTERLEUKIN 13;

EID: 84964294858     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/1568026616666150930120803     Document Type: Article
Times cited : (19)

References (51)
  • 2
    • 84876894419 scopus 로고    scopus 로고
    • From phenotypes to endotypes to asthma treatment
    • Agache, I. O. From phenotypes to endotypes to asthma treatment. Curr. Opin. Allergy Clin. Immunol., 2013, 13 (3), 249-56;
    • (2013) Curr. Opin. Allergy Clin. Immunol. , vol.13 , Issue.3 , pp. 249-256
    • Agache, I.O.1
  • 4
    • 52049087356 scopus 로고    scopus 로고
    • Endotyping asthma: New insights into key pathogenic mechanisms in a complex, heterogeneous disease
    • Anderson, G. P. Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease. Lancet, 2008, 372 (9643), 1107-19.
    • (2008) Lancet , vol.372 , Issue.9643 , pp. 1107-1119
    • Erson, G.P.1
  • 5
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin. Pharmacol. Ther., 2001, 69 (3), 89-95.
    • (2001) Clin. Pharmacol. Ther , vol.69 , Issue.3 , pp. 89-95
  • 6
    • 33847759164 scopus 로고    scopus 로고
    • Tools used to measure airway remodelling in research
    • Bergeron, C.; Tulic, M. K.; Hamid, Q. Tools used to measure airway remodelling in research. Eur. Respir. J., 2007, 29 (3), 596-604.
    • (2007) Eur. Respir. J. , vol.29 , Issue.3 , pp. 596-604
    • Bergeron, C.1    Tulic, M.K.2    Hamid, Q.3
  • 7
    • 79955036361 scopus 로고    scopus 로고
    • Non-invasive assessment of asthmatic inflammation: From bench to bedside
    • Loukides, S.; Kostikas, K.; Bakakos, P. Non-invasive assessment of asthmatic inflammation: from bench to bedside. Curr. Med. Chem., 2011,18 (10), 1413-4.
    • (2011) Curr. Med. Chem. , vol.18 , Issue.10 , pp. 1413-1414
    • Loukides, S.1    Kostikas, K.2    Bakakos, P.3
  • 9
    • 34249732096 scopus 로고    scopus 로고
    • Epidemiological and immunological evidence for the hygiene hypothesis
    • Garn, H.; Renz, H. Epidemiological and immunological evidence for the hygiene hypothesis. Immunobiology, 2007, 212 (6), 441-52.
    • (2007) Immunobiology , vol.212 , Issue.6 , pp. 441-452
    • Garn, H.1    Renz, H.2
  • 10
    • 84887995285 scopus 로고    scopus 로고
    • Complex phenotypes in asthma: Current definitions. Pulm. Pharmacol
    • Wenzel, S. E. Complex phenotypes in asthma: current definitions. Pulm. Pharmacol. Ther., 2013, 26 (6), 710-5.
    • (2013) Ther. , vol.26 , Issue.6 , pp. 710-715
    • Wenzel, S.E.1
  • 12
    • 0028894912 scopus 로고
    • Changing patterns of childhood infection and the rise in allergic disease.
    • Shaheen, S. O. Changing patterns of childhood infection and the rise in allergic disease. Clin. Exp. Allergy, 1995, 25 (11), 1034-7.
    • (1995) Clin. Exp. Allergy , vol.25 , Issue.11 , pp. 1034-1037
    • Shaheen, S.O.1
  • 13
    • 84862024217 scopus 로고    scopus 로고
    • Untangling asthma phenotypes and endotypes
    • Agache, I.; Akdis, C.; Jutel, M.; Virchow, J. C. Untangling asthma phenotypes and endotypes. Allergy, 2012, 67 (7), 835-46.
    • (2012) Allergy , vol.67 , Issue.7 , pp. 835-846
    • Agache, I.1    Akdis, C.2    Jutel, M.3    Virchow, J.C.4
  • 14
    • 79955026629 scopus 로고    scopus 로고
    • Induced sputum in asthma: From bench to bedside
    • Bakakos, P.; Schleich, F.; Alchanatis, M.; Louis, R. Induced sputum in asthma: from bench to bedside. Curr. Med. Chem., 2011, 18 (10), 1415-22.
    • (2011) Curr. Med. Chem. , vol.18 , Issue.10 , pp. 1415-1422
    • Bakakos, P.1    Schleich, F.2    Alchanatis, M.3    Louis, R.4
  • 16
    • 77951665424 scopus 로고    scopus 로고
    • Bleecker, E. R. Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes.
    • Hastie, A. T.; Moore, W. C.; Meyers, D. A.; Vestal, P. L.; Li, H.; Peters, S. P.; Bleecker, E. R. Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. J. Allergy Clin. Immunol., 2010, 125 (5), 1028-1036 e13.
    • (2010) J. Allergy Clin. Immunol. , vol.125 , Issue.5 , pp. 1028-1036
    • Hastie, A.T.1    Moore, W.C.2    Meyers, D.A.3    Vestal, P.L.4    Li, H.5    Peters, S.P.6
  • 19
    • 84864022085 scopus 로고    scopus 로고
    • Sputum inflammatory phenotypes are not stable in children with asthma
    • Fleming, L.; Tsartsali, L.; Wilson, N.; Regamey, N.; Bush, A. Sputum inflammatory phenotypes are not stable in children with asthma. Thorax, 2012, 67 (8), 675-81.
    • (2012) Thorax , vol.67 , Issue.8 , pp. 675-681
    • Fleming, L.1    Tsartsali, L.2    Wilson, N.3    Regamey, N.4    Bush, A.5
  • 22
    • 84903834828 scopus 로고    scopus 로고
    • Louis, R. Importance of concomitant local and systemic eosinophilia in uncontrolled asthma
    • Schleich, F. N.; Chevremont, A.; Paulus, V.; Henket, M.; Manise, M.; Seidel, L.; Louis, R. Importance of concomitant local and systemic eosinophilia in uncontrolled asthma. Eur. Respir. J., 2014, 44 (1), 97-108.
    • (2014) . Eur. Respir. J. , vol.44 , Issue.1 , pp. 97-108
    • Schleich, F.N.1    Chevremont, A.2    Paulus, V.3    Henket, M.4    Manise, M.5    Seidel, L.6
  • 23
    • 84903852026 scopus 로고    scopus 로고
    • Airway and systemic eosinophilia in asthma: Does site matter
    • Kostikas, K.; Zervas, E.; Gaga, M. Airway and systemic eosinophilia in asthma: does site matter? Eur. Respir. J., 2014, 44 (1), 14-6.
    • (2014) Eur. Respir. J. , vol.44 , Issue.1 , pp. 14-16
    • Kostikas, K.1    Zervas, E.2    Gaga, M.3
  • 24
    • 79955022468 scopus 로고    scopus 로고
    • Exhaled nitric oxide in asthma in adults: The end is the beginning
    • Kostikas, K.; Minas, M.; Papaioannou, A. I.; Papiris, S.; Dweik, R. A. Exhaled nitric oxide in asthma in adults: the end is the beginning? Curr. Med. Chem., 2011, 18 (10), 1423-31.
    • (2011) Curr. Med. Chem. , vol.18 , Issue.10 , pp. 1423-1431
    • Kostikas, K.1    Minas, M.2    Papaioannou, A.I.3    Papiris, S.4    Dweik, R.A.5
  • 25
    • 51649092146 scopus 로고    scopus 로고
    • Noninvasive evaluation of airway inflammation in asthmatic patients who smoke: Implications for application in clinical practice. Ann
    • quiz 232-4, 278
    • Bessa, V.; Tseliou, E.; Bakakos, P.; Loukides, S. Noninvasive evaluation of airway inflammation in asthmatic patients who smoke: implications for application in clinical practice. Ann. Allergy Asthma Immunol., 2008, 101 (3), 226-32; quiz 232-4, 278.
    • (2008) Allergy Asthma Immunol. , vol.101 , Issue.3 , pp. 226-232
    • Bessa, V.1    Tseliou, E.2    Bakakos, P.3    Loukides, S.4
  • 26
    • 0032707922 scopus 로고    scopus 로고
    • Influence of atopy on exhaled nitric oxide in patients with stable asthma and rhinitis
    • Gratziou, C.; Lignos, M.; Dassiou, M.; Roussos, C. Influence of atopy on exhaled nitric oxide in patients with stable asthma and rhinitis. Eur. Respir. J., 1999, 14 (4), 897-901.
    • (1999) . Eur. Respir. J. , vol.14 , Issue.4 , pp. 897-901
    • Gratziou, C.1    Lignos, M.2    Dassiou, M.3    Roussos, C.4
  • 27
    • 33644773052 scopus 로고    scopus 로고
    • The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: An observational study in adults with asthma.
    • Berry, M. A.; Shaw, D. E.; Green, R. H.; Brightling, C. E.; Wardlaw, A. J.; Pavord, I. D. The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma. Clin. Exp. Allergy, 2005, 35 (9), 1175-9.
    • (2005) Clin. Exp. Allergy , vol.35 , Issue.9 , pp. 1175-1179
    • Berry, M.A.1    Shaw, D.E.2    Green, R.H.3    Brightling, C.E.4    Wardlaw, A.J.5    Pavord, I.D.6
  • 28
    • 78649530294 scopus 로고    scopus 로고
    • Exhaled nitric oxide thresholds associated with a sputum eosinophil count >/=3% in a cohort of unselected patients with asthma
    • Schleich, F. N.; Seidel, L.; Sele, J.; Manise, M.; Quaedvlieg, V.; Michils, A.; Louis, R. Exhaled nitric oxide thresholds associated with a sputum eosinophil count >/=3% in a cohort of unselected patients with asthma. Thorax, 2010, 65 (12), 1039-44.
    • (2010) Thorax , vol.65 , Issue.12 , pp. 1039-1044
    • Schleich, F.N.1    Seidel, L.2    Sele, J.3    Manise, M.4    Quaedvlieg, V.5    Michils, A.6    Louis, R.7
  • 30
    • 34247485053 scopus 로고    scopus 로고
    • Noneosinophilic asthma: A distinct clinical and pathologic phenotype
    • quiz 1053-4
    • Haldar, P.; Pavord, I. D. Noneosinophilic asthma: a distinct clinical and pathologic phenotype. J. Allergy Clin. Immunol., 2007, 119 (5), 1043-52; quiz 1053-4.
    • (2007) J. Allergy Clin. Immunol , vol.119 , Issue.5 , pp. 1043-1052
    • Haldar, P.1    Pavord, I.D.2
  • 31
    • 0032875377 scopus 로고    scopus 로고
    • Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics.
    • Wenzel, S. E.; Schwartz, L. B.; Langmack, E. L.; Halliday, J. L.; Trudeau, J. B.; Gibbs, R. L.; Chu, H. W. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am. J. Respir. Crit. Care Med., 1999, 160 (3), 1001-8.
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , Issue.3 , pp. 1001-1008
    • Wenzel, S.E.1    Schwartz, L.B.2    Langmack, E.L.3    Halliday, J.L.4    Trudeau, J.B.5    Gibbs, R.L.6    Chu, H.W.7
  • 32
    • 84875257590 scopus 로고    scopus 로고
    • Smoking and asthma: Dangerous liaisons
    • Polosa, R.; Thomson, N. C. Smoking and asthma: dangerous liaisons. Eur. Respir. J., 2013, 41 (3), 716-26.
    • (2013) Eur. Respir. J. , vol.41 , Issue.3 , pp. 716-726
    • Polosa, R.1    Thomson, N.C.2
  • 35
    • 77951666051 scopus 로고    scopus 로고
    • Variability of sputum inflammatory cells in asthmatic patients receiving corticosteroid therapy: A prospective study using multiple samples.
    • Al-Samri, M. T.; Benedetti, A.; Prefontaine, D.; Olivenstein, R.; Lemiere, C.; Nair, P.; Martin, J. G.; Hamid, Q. Variability of sputum inflammatory cells in asthmatic patients receiving corticosteroid therapy: A prospective study using multiple samples. J. Allergy Clin. Immunol., 2010, 125 (5), 1161-1163 e4.
    • (2010) J. Allergy Clin. Immunol. , vol.125 , Issue.5 , pp. 1161-1163
    • Al-Samri, M.T.1    Benedetti, A.2    Prefontaine, D.3    Olivenstein, R.4    Lemiere, C.5    Nair, P.6    Martin, J.G.7    Hamid, Q.8
  • 37
    • 77956361521 scopus 로고    scopus 로고
    • Asthma in older adults
    • Gibson, P. G.; McDonald, V. M.; Marks, G. B. Asthma in older adults. Lancet, 2010, 376 (9743), 803-13.
    • (2010) Lancet , vol.376 , Issue.9743 , pp. 803-813
    • Gibson, P.G.1    McDonald, V.M.2    Marks, G.B.3
  • 38
    • 84860679595 scopus 로고    scopus 로고
    • Asthma phenotypes: The evolution from clinical to molecular approaches.
    • Wenzel, S. E. Asthma phenotypes: the evolution from clinical to molecular approaches. Nat. Med., 2012, 18 (5), 716-25.
    • (2012) Nat. Med. , vol.18 , Issue.5 , pp. 716-725
    • Wenzel, S.E.1
  • 40
    • 84858720510 scopus 로고    scopus 로고
    • Proteomics in asthma and COPD phenotypes and endotypes for biomarker discovery and improved understanding of disease entities
    • O'Neil, S. E.; Lundback, B.; Lotvall, J. Proteomics in asthma and COPD phenotypes and endotypes for biomarker discovery and improved understanding of disease entities. J. Proteomics, 2011, 75 (1), 192-201.
    • (2011) J. Proteomics , vol.75 , Issue.1 , pp. 192-201
    • O'neil, S.E.1    Lundback, B.2    Lotvall, J.3
  • 41
    • 84913557801 scopus 로고    scopus 로고
    • Asthma: Pathogenesis and novel drugs for treatment
    • g5517
    • Olin, J. T.; Wechsler, M. E. Asthma: pathogenesis and novel drugs for treatment. BMJ, 2014, 349, g5517.
    • (2014) BMJ , pp. 349
    • Olin, J.T.1    Wechsler, M.E.2
  • 44
    • 77949596686 scopus 로고
    • Does obesity produce a distinct asthma phenotype
    • Lugogo, N. L.; Kraft, M.; Dixon, A. E. Does obesity produce a distinct asthma phenotype? J. Appl. Physiol. (1985), 108 (3), 729-34.
    • (1985) J. Appl. Physiol , vol.108 , Issue.3 , pp. 729-734
    • Lugogo, N.L.1    Kraft, M.2    Dixon, A.E.3
  • 47
    • 84865145614 scopus 로고    scopus 로고
    • Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
    • Pavord, I. D.; Korn, S.; Howarth, P.; Bleecker, E. R.; Buhl, R.; Keene, O. N.; Ortega, H.; Chanez, P. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet, 2012, 380 (9842), 651-9.
    • (2012) Lancet , vol.380 , Issue.9842 , pp. 651-659
    • Pavord, I.D.1    Korn, S.2    Howarth, P.3    Bleecker, E.R.4    Buhl, R.5    Keene, O.N.6    Ortega, H.7    Chanez, P.8
  • 48
    • 84921321823 scopus 로고    scopus 로고
    • External validation of blood eosinophils, FENO and serum periostin as surrogates for sputum eosinophils in asthma
    • Wagener, A. H.; de Nijs, S. B.; Lutter, R.; Sousa, A. R.; Weersink, E. J.; Bel, E. H.; Sterk, P. J. External validation of blood eosinophils, FENO and serum periostin as surrogates for sputum eosinophils in asthma. Thorax, 2015, 70 (2), 115-20.
    • (2015) Thorax , vol.70 , Issue.2 , pp. 115-120
    • Wagener, A.H.1    De Nijs, S.B.2    Lutter, R.3    Sousa, A.R.4    Weersink, E.J.5    Bel, E.H.6    Sterk, P.J.7


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