-
1
-
-
2342590065
-
The global burden of asthma: Executive summary of the GINA dissemination committee report
-
Masoli M, Fabian D, Holt S., Beasley R. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004; 59:469-78.
-
(2004)
Allergy
, vol.59
, pp. 469-478
-
-
Masoli, M.1
Fabian, D.2
Holt, S.3
Beasley, R.4
-
3
-
-
0035004903
-
Inhaled corticosteroids: Impact on asthma morbidity and mortallty
-
Suissa S. Ernst P. Inhaled corticosteroids: impact on asthma morbidity and mortallty. J Allergy Clin Immunol 2001; 107:937-44.
-
(2001)
J Allergy Clin Immunol
, vol.107
, pp. 937-944
-
-
Suissa, S.1
Ernst, P.2
-
4
-
-
0034601431
-
Low-dose inhaled corticosteroids and the prevention of death from asthma
-
Suissa S. Ernst R Benayoun S. Baltzan M. Cai B. Low-dose inhaled corticosteroids and the prevention of death from asthma. N Engl J Med 2000; 343:332-6.
-
(2000)
N Engl J Med
, vol.343
, pp. 332-336
-
-
Suissa, S.1
Ernst, R.2
Benayoun, S.3
Baltzan, M.4
Cai, B.5
-
6
-
-
3543035759
-
Worldwide variations in the prevalence of asthma symptoms: The international study of asthma and allergies in childhood (ISAAC)
-
Pearce N. Aïtkhaled N. Beasley R. Mallol J, Keil U. Mitchell E; the ISAAC Phase Three Study Group. Worldwide variations in the prevalence of asthma symptoms: the International Study of Asthma and Allergies in Childhood (ISAAC). Eur Respir J 1998; 12:315-35.
-
(1998)
Eur Respir J
, vol.12
, pp. 315-335
-
-
Pearce, N.1
Aïtkhaled, N.2
Beasley, R.3
Mallol, J.4
Keil, U.5
Mitchell, E.6
-
7
-
-
84866752292
-
Trends in asthma prevalence, health care use, and mortality in the United States, 2001-2010
-
Akinbami LJ. Moorman JE. Bailey C. Zahran HS. King M. Johnson CA. et al. Trends in asthma prevalence, health care use, and mortality in the United States, 2001-2010. NCHS Data Brief 2012:94:1-3.
-
(2012)
NCHS Data Brief
, vol.94
, pp. 1-3
-
-
Akinbami, L.J.1
Moorman, J.E.2
Bailey, C.3
Zahran, H.S.4
King, M.5
Johnson, C.A.6
-
8
-
-
84878636867
-
Childhood asthma and allergies in urban, semiurban, and rural residential sectors in Chile
-
Kausel L, Boneberger A, Calvo M., Radon K. Childhood asthma and allergies in urban, semiurban, and rural residential sectors in Chile. Scientific World Journal 2013:2013:937935.
-
(2013)
Scientific World Journal
, vol.2013
-
-
Kausel, L.1
Boneberger, A.2
Calvo, M.3
Radon, K.4
-
9
-
-
79955951398
-
Vital signs: Asthma prevalence, disease characteristics, and self-management education: United states, 2001-2009
-
Vital signs: asthma prevalence, disease characteristics, and self-management education: United States, 2001-2009. MMWR Morb Mortal Wkly Rep 2011; 60:547-52.
-
(2011)
MMWR Morb Mortal Wkly Rep
, vol.60
, pp. 547-552
-
-
-
10
-
-
0028047804
-
Prevalence of asthma and atopy in two areas of west and east Germany
-
Von Mutius E., Martinez FD, Fritzsch C, Nicolai T Roell G, Thiemann HH. Prevalence of asthma and atopy in two areas of West and East Germany. Am j Respir Crit Care Med 1994; 149:358-64.
-
(1994)
Am J Respir Crit Care Med
, vol.149
, pp. 358-364
-
-
Von Mutius, E.1
Martinez, F.D.2
Fritzsch, C.3
Nicolai, T.4
Roell, G.5
Thiemann, H.H.6
-
11
-
-
0038460312
-
Urban traffic and pollutant exposure related to respiratory outcomes and atopy in a large sample of children
-
Nicolai T, Carr D, Weiland S.K., Duhme H., von Ehrenstein O, Wagner C, et al. Urban traffic and pollutant exposure related to respiratory outcomes and atopy in a large sample of children. Eur Respir J 2003; 21:956-63.
-
(2003)
Eur Respir J
, vol.21
, pp. 956-963
-
-
Nicolai, T.1
Carr, D.2
Weiland, S.K.3
Duhme, H.4
Von Ehrenstein, O.5
Wagner, C.6
-
12
-
-
77149148731
-
Effect of early life exposure to air pollution on development of childhood asthma
-
Clark NA, Demers PA, Karr C.J., Koehoorn M., Lencar C, Tamburic L, et al. Effect of early life exposure to air pollution on development of childhood asthma. Environ Health Perspect 2010; 118:284-90.
-
(2010)
Environ Health Perspect
, vol.118
, pp. 284-290
-
-
Clark, N.A.1
Demers, P.A.2
Karr, C.J.3
Koehoorn, M.4
Lencar, C.5
Tamburic, L.6
-
13
-
-
0031953731
-
Health effects of passive smoking. 6. Parental smoking and childhood asthma: Longitudinal and case-control studies
-
Strachan DR Cook DG. Health effects of passive smoking. 6. Parental smoking and childhood asthma: longitudinal and case-control studies. Thorax 1998; 53:204-12.
-
(1998)
Thorax
, vol.53
, pp. 204-212
-
-
Strachan, D.R.1
Cook, D.G.2
-
14
-
-
0344065387
-
Prospective study of body mass index, weight change, and riskof adult-onset asthma in women
-
Camargo CAJr, Weiss ST, Zhang S, Willett W.C., Speizer FE. Prospective study of body mass index, weight change, and riskof adult-onset asthma in women. Arch Intern Med 1999; 159:2582-8.
-
(1999)
Arch Intern Med
, vol.159
, pp. 2582-2588
-
-
Camargo, C.A.1
Weiss, S.T.2
Zhang, S.3
Willett, W.C.4
Speizer, F.E.5
-
15
-
-
79951972586
-
Exposure to environmental microorganisms and childhood asthma
-
Ege MJ, Mayer M, Normand A.C., Genuneit J., Cookson WO, Braun-Fahrlander C, et al. Exposure to environmental microorganisms and childhood asthma. N Engl J Med 2011:364:701-9.
-
(2011)
N Engl J Med
, vol.364
, pp. 701-709
-
-
Ege, M.J.1
Mayer, M.2
Normand, A.C.3
Genuneit, J.4
Cookson, W.O.5
Braun-Fahrlander, C.6
-
16
-
-
79551502309
-
Effect of day care attendance on sensitization and atopic wheezing differs by toll-like receptor 2 genotype in 2 population-based birth cohort studies
-
e1-9
-
Custovic A, Rothers J, Stern D., Simpson A, Woodcock A, Wright AL, et al. Effect of day care attendance on sensitization and atopic wheezing differs by Toll-like receptor 2 genotype in 2 population-based birth cohort studies. J Allergy Clin Immunol 2011; 127:390-97 e1-9.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 390-397
-
-
Custovic, A.1
Rothers, J.2
Stern, D.3
Simpson, A.4
Woodcock, A.5
Wright, A.L.6
-
17
-
-
84858771950
-
Risk of asthma and allergic outcomes in the offspring in relation to maternal food consumption during pregnancy: A finnish birth cohort study
-
Erkkola M, Nwaru Bl, Kaila M, Kronberg-Kippila C, Honen J., Simell O, et al. Risk of asthma and allergic outcomes in the offspring in relation to maternal food consumption during pregnancy: a Finnish birth cohort study. Pediatr Allergy Immunol 2012; 23:186-94.
-
(2012)
Pediatr Allergy Immunol
, vol.23
, pp. 186-194
-
-
Erkkola, M.1
Bl, N.2
Kaila, M.3
Kronberg-Kippila, C.4
Honen, J.5
Simell, O.6
-
18
-
-
84871714836
-
Timing of infant feeding in relation to childhood asthma and allergic diseases
-
Nwaru Bl, Takkinen HM, Niemela O, Kaila M, Erkkola M, Ahonen S, et al. Timing of infant feeding in relation to childhood asthma and allergic diseases. J Allergy Clin Immunol 2013; 131:78-86.
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 78-86
-
-
Bl, N.1
Takkinen, H.M.2
Niemela, O.3
Kaila, M.4
Erkkola, M.5
Ahonen, S.6
-
19
-
-
35148862816
-
Worldwide trends in the prevalence of asthma symptoms: Phase III of the international study of asthma and allergies in childhood (ISAAC)
-
Pearce N, Ait-Khaled N, Beasley R., Mallol J, Keil U, Mitchell E., et al. Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax 2007; 62:758-66.
-
(2007)
Thorax
, vol.62
, pp. 758-766
-
-
Pearce, N.1
Ait-Khaled, N.2
Beasley, R.3
Mallol, J.4
Keil, U.5
Mitchell, E.6
-
20
-
-
79551480908
-
The burden of adult asthma in the United States: Evidence from the medical expenditure panel suney
-
e1-3
-
Sullivan PW. Ghushchyan VH. Slejko JF, Belozeroff V, Globe DR, Lin SL. The burden of adult asthma in the United States: evidence from the Medical Expenditure Panel Suney. J Allergy Clin Immunol 2011; 127:363-69 e1-3.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 363-369
-
-
Sullivan, P.W.1
Ghushchyan, V.H.2
Slejko, J.F.3
Belozeroff, V.4
Globe, D.R.5
Lin, S.L.6
-
21
-
-
28844471909
-
School absenteeism in children with asthma in a los angeles inner city school
-
Bonilla S, Kehl S, Kwong K.Y., Morphew T., Kachru R, Jones CA. School absenteeism in children with asthma in a Los Angeles inner city school. J Pediatr 2005; 147:802-6.
-
(2005)
J Pediatr
, vol.147
, pp. 802-806
-
-
Bonilla, S.1
Kehl, S.2
Kwong, K.Y.3
Morphew, T.4
Kachru, R.5
Jones, C.A.6
-
22
-
-
0034908409
-
School attendance and school performance: A population-based study of children with asthma
-
Silverstein MD, Mair JE, Katusic SK, Wollan PC, O'Connell EJ, Yunginger JW School attendance and school performance: a population-based study of children with asthma. J Pediatr 2001; 139:278-83.
-
(2001)
J Pediatr
, vol.139
, pp. 278-283
-
-
Silverstein, M.D.1
Mair, J.E.2
Katusic, S.K.3
Wollan, P.C.4
O'Connell, E.J.5
Yunginger, J.W.6
-
24
-
-
84893513577
-
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
-
Chung KR Wenzel SE, Brozek JL, Bush A, Castro M, Sterk PJ, et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J 2014; 43:343-73.
-
(2014)
Eur Respir J
, vol.43
, pp. 343-373
-
-
Chung, K.R.1
Wenzel, S.E.2
Brozek, J.L.3
Bush, A.4
Castro, M.5
Sterk, P.J.6
-
25
-
-
84875229819
-
Clinical phenotypes of chronicobstructive pulmonary disease and asthma: Recent advances
-
quiz 35.
-
Carolan BJ, Sutherland ER. Clinical phenotypes of chronicobstructive pulmonary disease and asthma: recent advances. J Allergy Clin Immunol 2013; 131:627-34; quiz 35.
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 627-634
-
-
Carolan, B.J.1
Sutherland, E.R.2
-
26
-
-
84860679595
-
Asthma phenotypes: The evolution from clinical to molecular approaches
-
Wenzel SE. Asthma phenotypes: the evolution from clinical to molecular approaches. Not Med 2012; 18:716-25.
-
(2012)
Not Med
, vol.18
, pp. 716-725
-
-
Wenzel, S.E.1
-
27
-
-
33747756534
-
Asthma: Defining of the persistent adult phenotypes
-
Wenzel SE. Asthma: defining of the persistent adult phenotypes. Lancet 2006; 368:804-13.
-
(2006)
Lancet
, vol.368
, pp. 804-813
-
-
Wenzel, S.E.1
-
28
-
-
79551500941
-
Heterogeneity of severe asthma in childhood: Confirmation by cluster analysis of children in the national institutes of health/National heart, lung, and blood institute severe asthma research program
-
e1-13.
-
Fitzpatrick AM, Teague WG, Meyers D.A., Peters SR Li X, Li H, et al. Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. J Allergy Clin Immunol 2011:127:382-89 e1-13.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 382-389
-
-
Fitzpatrick, A.M.1
Teague, W.G.2
Meyers, D.A.3
Peters, S.R.4
Li, X.5
Li, H.6
-
29
-
-
84895058912
-
Childhood asthma clusters and response to therapy in clinical trials
-
Chang TS, Lemanske RF Jr, Mauger DT, Fitzpatrick AM, Sorkness CA, Szefler SJ, et al. Childhood asthma clusters and response to therapy in clinical trials. J Allergy Clin Immunol 2014:133:363-9
-
(2014)
J Allergy Clin Immunol
, vol.133
, pp. 363-369
-
-
Chang, T.S.1
Lemanske, R.F.2
Mauger, D.T.3
Fitzpatrick, A.M.4
Sorkness, C.A.5
Szefler, S.J.6
-
30
-
-
0025598333
-
Genetics of asthma and hay fever in Australian mms
-
Duffy DL, Martin NG, Battistutta D, Hopper JL, Mathews JD. Genetics of asthma and hay fever in Australian Mms. Am Rev Respir Dis 1990; 142:1351-8.
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 1351-1358
-
-
Duffy, D.L.1
Martin, N.G.2
Battistutta, D.3
Hopper, J.L.4
Mathews, J.D.5
-
31
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
Moffatt MF, Gut IG, Demenais F, Strachan DR Bouzigon E, Heath S, et al. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 2010; 363:1211-21.
-
(2010)
N Engl J Med
, vol.363
, pp. 1211-1221
-
-
Moffatt, M.F.1
Gut, I.G.2
Demenais, F.3
Strachan, D.R.4
Bouzigon, E.5
Heath, S.6
-
32
-
-
84861667806
-
DNA methylation of TH1/TH2 cytokine genes affects sensitization and progress of experimental asthma
-
Brand S, Kesper DA, Teich R, Kilic-Niebergall E, Pinkenburg O, Bothur E, et al. DNA methylation of TH1/TH2 cytokine genes affects sensitization and progress of experimental asthma. J Allergy Clin Immunol 2012; 129:1602-10e6.
-
(2012)
J Allergy Clin Immunol
, vol.129
, pp. 1602-10e6
-
-
Brand, S.1
Kesper, D.A.2
Teich, R.3
Kilic-Niebergall, E.4
Pinkenburg, O.5
Bothur, E.6
-
33
-
-
84862008174
-
Relation of DNA methylation of 5'-cpg island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma
-
Perera F, Tang WY, Herbstman J, Tang D., Levin L, Miller R, et al. Relation of DNA methylation of 5'-CpG island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma. PLoS One 2009; 4:e4488.
-
(2009)
PLoS One
, vol.4
-
-
Perera, F.1
Tang, W.Y.2
Herbstman, J.3
Tang, D.4
Levin, L.5
Miller, R.6
-
34
-
-
84867251622
-
450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy
-
Joubert BR, Haberg SE, Nilsen R.M., Wang X, Vollset SE, Murphy SK, et al. 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. Environ Health Perspect 2012; 120:1425-31.
-
(2012)
Environ Health Perspect
, vol.120
, pp. 1425-1431
-
-
Joubert, B.R.1
Haberg, S.E.2
Nilsen, R.M.3
Wang, X.4
Vollset, S.E.5
Murphy, S.K.6
-
35
-
-
84871557810
-
Elevated risk of asthma after hospitalization for respiratory syncytial virus infection in infancy
-
Szabo SM, Levy AR, Gooch K.L., Bradt R Wijaya H, Mitchell I. Elevated risk of asthma after hospitalization for respiratory syncytial virus infection in infancy. Paediatr Respir Rev 2013; 13(suppl 2):S9-15.
-
(2013)
Paediatr Respir Rev
, vol.13
, pp. S9-15
-
-
Szabo, S.M.1
Levy, A.R.2
Gooch, K.L.3
Bradt, R.4
Wijaya, H.5
Mitchell, I.6
-
36
-
-
78650807878
-
The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airways
-
Navarro S, Cossalter G, Chiavaroli C., Kanda A, Fleury S, Lazzari A., et al. The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airways. Mucosal Immunol 2011; 4:53-65.
-
(2011)
Mucosal Immunol
, vol.4
, pp. 53-65
-
-
Navarro, S.1
Cossalter, G.2
Chiavaroli, C.3
Kanda, A.4
Fleury, S.5
Lazzari, A.6
-
37
-
-
84890350608
-
Allergen recognition by innate immune cells: Critical role of dendritic and epithelial cells
-
Salazar F, Ghaemmaghami AM. Allergen recognition by innate immune cells: critical role of dendritic and epithelial cells. Front Immunol 2013; 4:356.
-
(2013)
Front Immunol
, vol.4
, pp. 356
-
-
Salazar, F.1
Ghaemmaghami, A.M.2
-
38
-
-
84860691114
-
The airway epithelium in asthma
-
LambrechtBN, Hammad H. The airway epithelium in asthma. Nat Med 2012; 18:684-92.
-
(2012)
Nat Med
, vol.18
, pp. 684-692
-
-
Lambrecht, B.N.1
Hammad, H.2
-
39
-
-
77951087220
-
CCL20/CCR6 blockade enhances immunity to RSV by impairing recruitment of DC
-
Kallal LE, Schaller MA, Lindell D.M., Lira SA, Lukacs NW. CCL20/CCR6 blockade enhances immunity to RSV by impairing recruitment of DC. Eurj Immunol 2010; 40:1042-52.
-
(2010)
Eurj Immunol
, vol.40
, pp. 1042-1052
-
-
Kallal, L.E.1
Schaller, M.A.2
Lindell, D.M.3
Lira, S.A.4
Lukacs, N.W.5
-
40
-
-
16244412881
-
Asthmatic bronchial epithelium activated by the proteolytic allergen der p 1 increases selective dendritic cell recruitment
-
Pichavant M, Charbonnier AS, Tarants, Brichet A, Wallaert B, Pestel J, et al. Asthmatic bronchial epithelium activated by the proteolytic allergen Der p 1 increases selective dendritic cell recruitment, J Allergy Clin Immunol 2005; 115:771-8.
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 771-778
-
-
Pichavant, M.1
Charbonnier, A.S.2
Tarants3
Brichet, A.4
Wallaert, B.5
Pestel, J.6
-
41
-
-
84859404292
-
Lung dendritic cells in respiratory viral infection and asthma: From protection to immunopathology
-
Lambrecht BN, Hammad H. Lung dendritic cells in respiratory viral infection and asthma: from protection to immunopathology. Annu Rev Immunol 2012; 30:243-70.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 243-270
-
-
Lambrecht, B.N.1
Hammad, H.2
-
42
-
-
33947322376
-
Lung dendritic cell migration
-
Hammad H, Lambrecht BN. Lung dendritic cell migration. Adv Immunol 2007; 93:265-78.
-
(2007)
Adv Immunol
, vol.93
, pp. 265-278
-
-
Hammad, H.1
Lambrecht, B.N.2
-
43
-
-
77958165107
-
Nonredundant role of CCRL2 in lung dendritic cell trafficking
-
Otero K, Vecchi A, Hirsch E., Kearley J, Vermi W, Del Prete A, et al. Nonredundant role of CCRL2 in lung dendritic cell trafficking. Blood 2010; 116:2942-9.
-
(2010)
Blood
, vol.116
, pp. 2942-2949
-
-
Otero, K.1
Vecchi, A.2
Hirsch, E.3
Kearley, J.4
Vermi, W.5
Del Prete, A.6
-
44
-
-
84878108325
-
Role of plasmacytoid dendritic cell subsets in allergic asthma
-
Maazi H, Lam J, Lombardi V., Akbari O. Role of plasmacytoid dendritic cell subsets in allergic asthma. Allergy 2013; 68:695-701.
-
(2013)
Allergy
, vol.68
, pp. 695-701
-
-
Maazi, H.1
Lam, J.2
Lombardi, V.3
Akbari, O.4
-
45
-
-
0026610142
-
Predominant TH2-like bronchoalveolarT-lymphocyte population in atopic asthma
-
Robinson DS, Hamid Q, Ying S., Tsicopoulos A, Barkans J, Bentley A.M., et al. Predominant TH2-like bronchoalveolarT-lymphocyte population in atopic asthma. N Engl J Med 1992;326:298-304.
-
(1992)
N Engl J Med
, vol.326
, pp. 298-304
-
-
Robinson, D.S.1
Hamid, Q.2
Ying, S.3
Tsicopoulos, A.4
Barkans, J.5
Bentley, A.M.6
-
46
-
-
77649198441
-
Investigationaltherapeuticstargetingthe IL-4/IL-13 / STAT-6 pathway for the treatment of asthma
-
Oh CK, Geba GR Molfino N. Investigationaltherapeuticstargetingthe IL-4/IL-13 / STAT-6 pathway for the treatment of asthma. Eur Respir Rev 2010; 19:46-54.
-
(2010)
Eur Respir Rev
, vol.19
, pp. 46-54
-
-
Oh, C.K.1
Geba, G.R.2
Molfino, N.3
-
47
-
-
35549003579
-
Regulation of interferon-gamma during innate and adaptive immune responses
-
Schoenborn JR, Wilson CB. Regulation of interferon-gamma during innate and adaptive immune responses. Adv Immunol 2007; 96:41-101.
-
(2007)
Adv Immunol
, vol.96
, pp. 41-101
-
-
Schoenborn, J.R.1
Wilson, C.B.2
-
48
-
-
79959937269
-
Th 17 cells: New playersin asthma pathogenesis
-
Cosmi L, Liotta F, Maggi E., Romagnani S, Annunziato F. Th 17 cells: new playersin asthma pathogenesis. Allergy 2011; 66:989-98.
-
(2011)
Allergy
, vol.66
, pp. 989-998
-
-
Cosmi, L.1
Liotta, F.2
Maggi, E.3
Romagnani, S.4
Annunziato, F.5
-
49
-
-
70349871248
-
Allergic sensitization through the airway primesTh 17-dependent neutrophilia and airway hyperresponsiveness
-
Wilson RH, Whitehead GS, Nakano H, Free M.E., Kolls JK, Cook DN. Allergic sensitization through the airway primesTh 17-dependent neutrophilia and airway hyperresponsiveness. Am j Respir Crit Care Med 2009; 180:720-30.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 720-730
-
-
Wilson, R.H.1
Whitehead, G.S.2
Nakano, H.3
Free, M.E.4
Kolls, J.K.5
Cook, D.N.6
-
50
-
-
84876942120
-
T cells in asthma: Influences of genetics, environment, and T-cell plasticity
-
quiz 75
-
Lloyd CM, Saglani S. T cells in asthma: influences of genetics, environment, and T-cell plasticity. J AllergyClin Immunol 2013; 131:1267-74; quiz 75.
-
(2013)
J AllergyClin Immunol
, vol.131
, pp. 1267-1274
-
-
Lloyd, C.M.1
Saglani, S.2
-
51
-
-
72849130777
-
House dust mite sublingual immunotherapy: The role for transforming growth factor-beta and functional regulatory T cells
-
O'Hehir R.E., Gardner LM, de Leon MP, Hales BJ, Biondo M, Douglass JA, et al. House dust mite sublingual immunotherapy: the role for transforming growth factor-beta and functional regulatory T cells. Am j Respir Crit Care Med 2009; 180:936-47.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 936-947
-
-
O'Hehir, R.E.1
Gardner, L.M.2
De Leon, M.P.3
Hales, B.J.4
Biondo, M.5
Douglass, J.A.6
-
53
-
-
77951817294
-
IL 25 elicits a multipotent progenitor cell population that promotes T(H) 2 cytokine responses
-
Saenz SA, Siracusa MC, Perrigoue JG, Spencer SR Urban JF Jr, Tocker JE, et al. IL 25 elicits a multipotent progenitor cell population that promotes T(H) 2 cytokine responses. Nature 2010; 464:1362-6.
-
(2010)
Nature
, vol.464
, pp. 1362-1366
-
-
Saenz, S.A.1
Siracusa, M.C.2
Perrigoue, J.G.3
Spencer, S.R.4
Urban, J.F.5
Tocker, J.E.6
-
54
-
-
0026315499
-
Eosinophil hematopoietins antagonize the programmed cell death of eosinophils. Cytokine and glucocorticoid effects on eosinophils maintained by endothelial cell-conditioned medium
-
Her E, Frazer J, Austen K.F., Owen WFJr. Eosinophil hematopoietins antagonize the programmed cell death of eosinophils. Cytokine and glucocorticoid effects on eosinophils maintained by endothelial cell-conditioned medium. J Clin Invest 1991; 88:1982-7.
-
(1991)
J Clin Invest
, vol.88
, pp. 1982-1987
-
-
Her, E.1
Frazer, J.2
Austen, K.F.3
Owen, W.F.4
-
55
-
-
84873408369
-
Targeting eosinophils in allergy, inflammation and beyond
-
Fulkerson PC, Rothenberg ME. Targeting eosinophils in allergy, inflammation and beyond. Nat Rev Drug Discov 2013; 12:117-29.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 117-129
-
-
Fulkerson, P.C.1
Rothenberg, M.E.2
-
56
-
-
49249130983
-
Siglec-F antibody ad ministration to mice selectively reduces blood and tissue eosinophils
-
Zimmermann N, McBride ML, YamadaY Hudson SA, Jones C, Cromie KD, et al. Siglec-F antibody ad ministration to mice selectively reduces blood and tissue eosinophils. Allergy 2008; 63:1156-63.
-
(2008)
Allergy
, vol.63
, pp. 1156-1163
-
-
Zimmermann, N.1
McBride, M.L.2
YamadaY Hudson, S.A.3
Jones, C.4
Cromie, K.D.5
-
57
-
-
0038044928
-
Ligation of siglec-8: A selective mechanism for induction of human eosinophil apoptosis
-
Nutku E, Aizawa H, Hudson SA Bochner BS. Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis. Blood 2003; 101:5014-20.
-
(2003)
Blood
, vol.101
, pp. 5014-5020
-
-
Nutku, E.1
Aizawa, H.2
Hudson, S.A.3
Bochner, B.S.4
-
58
-
-
84880546651
-
Eosinophils: Multifunctional and distinctive properties
-
Kita H. Eosinophils: multifunctional and distinctive properties. Int Arch Allergy Immunol 2013; 161(suppl 2):3-9.
-
(2013)
Int Arch Allergy Immunol
, vol.161
, pp. 3-9
-
-
Kita, H.1
-
59
-
-
42249088428
-
Eosinophils: Biological properties and role in health and disease
-
Hogan SR Rosenberg HF, Moqbel R, Phipps S, Foster PS, Lacy R et al. Eosinophils: biological properties and role in health and disease. Clin Exp Allergy 2008; 38:709-50.
-
(2008)
Clin Exp Allergy
, vol.38
, pp. 709-750
-
-
Hogan, S.R.1
Rosenberg, H.F.2
Moqbel, R.3
Phipps, S.4
Foster, P.S.5
Lacy, R.6
-
60
-
-
33644752698
-
Stem cell factor and its receptor c-kit as targets for inflammatory diseases
-
Reber L, Da Silva CA, Frossard N. Stem cell factor and its receptor c-Kit as targets for inflammatory diseases. Eurj Pharmacol 2006; 533:327-40.
-
(2006)
Eurj Pharmacol
, vol.533
, pp. 327-340
-
-
Reber, L.1
Da Silva, C.A.2
Frossard, N.3
-
61
-
-
79959334504
-
Pathophysiology of allergic inflammation
-
Barnes PJ. Pathophysiology of allergic inflammation. Immunol Rev 2011; 242:31-50.
-
(2011)
Immunol Rev
, vol.242
, pp. 31-50
-
-
Barnes, P.J.1
-
62
-
-
0032698182
-
Neutrophilic inflammation in severe persistent asthma
-
Jatakanon A, Uasuf C, Maziak W, Lim S, Chung KF, Barnes PJ. Neutrophilic inflammation in severe persistent asthma. Am J Respir Crit Care Med 1999; 160:1532-9.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1532-1539
-
-
Jatakanon, A.1
Uasuf, C.2
Maziak, W.3
Lim, S.4
Chung, K.F.5
Barnes, P.J.6
-
63
-
-
0029556368
-
Inhibition by dexamethasone of human neutrophil apoptosis in vitro
-
Kato T, Takeda X Nakada T, Sendo F Inhibition by dexamethasone of human neutrophil apoptosis in vitro. Nat Immun 1995; 14:198-208.
-
(1995)
Nat Immun
, vol.14
, pp. 198-208
-
-
Kato, T.1
Takeda, X.2
Nakada, T.3
Sendo, F.4
-
64
-
-
0029057979
-
Glucocorticoid treatment inhibits apoptosis in human neutrophils. Separation of survival and activation outcomes
-
Cox G. Glucocorticoid treatment inhibits apoptosis in human neutrophils. Separation of survival and activation outcomes. J Immunol 1995; 154:4719-25.
-
(1995)
J Immunol
, vol.154
, pp. 4719-4725
-
-
Cox, G.1
-
65
-
-
0343527389
-
Increased neutrophil numbers and ILS levels in airway secretions in acute severe asthma: Clinical and biologic significance
-
Ordonez CL, Shaughnessy TE, Matthay MA, Fahy JV. Increased neutrophil numbers and ILS levels in airway secretions in acute severe asthma: clinical and biologic significance. Am J Respir Crit Care Med 2000; 161:1185-90.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 1185-1190
-
-
Ordonez, C.L.1
Shaughnessy, T.E.2
Matthay, M.A.3
Fahy, J.V.4
-
66
-
-
0035891664
-
Remodeling in asthma and chronic obstructive lung disease
-
Jeffery PK. Remodeling in asthma and chronic obstructive lung disease. Am J Respir Crit Care Med 2001; 164:S28-38.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. S28-38
-
-
Jeffery, P.K.1
-
67
-
-
84988396851
-
IL-13, asthma, and glycosylation in airway epithelial repair
-
Chang C, ed. InTech
-
Wadsworth B, Yang J, Dorscheid D. IL-13, asthma, and glycosylation in airway epithelial repair. In: Chang C, ed. Carbohydrates - comprehensive studies on glycobiology and glycotechnology. InTech, 2012.
-
(2012)
Carbohydrates - Comprehensive Studies on Glycobiology and Glycotechnology
-
-
Wadsworth, B.1
Yang, J.2
Dorscheid, D.3
-
68
-
-
0024828192
-
Bronchial biopsies in asthma. An ultrastructural, quantitative study and correlation with hyperreactivity
-
Jeffery PK, Wardlaw AJ, Nelson F.C., Collins JV, Kay AB. Bronchial biopsies in asthma. An ultrastructural, quantitative study and correlation with hyperreactivity. Am Rev Respir Dis 1989; 140:1745-53.
-
(1989)
Am Rev Respir Dis
, vol.140
, pp. 1745-1753
-
-
Jeffery, P.K.1
Wardlaw, A.J.2
Nelson, F.C.3
Collins, J.V.4
Kay, A.B.5
-
69
-
-
0027284109
-
Bronchial epithelial shedding in asthmatics and non-asthmatics
-
Montefort S, Roche WR, Holgate ST. Bronchial epithelial shedding in asthmatics and non-asthmatics. Respir Med 1993; 87(suppl B):9-ll.
-
(1993)
Respir Med
, vol.87
, pp. 9-ll
-
-
Montefort, S.1
Roche, W.R.2
Holgate, S.T.3
-
70
-
-
80052219553
-
Defective epithelial barrier function in asthma
-
e1-12.
-
Xiao C, Puddicombe SM, Fields, Haywood J, Broughton-Head V, Puxeddu I. et al. Defective epithelial barrier function in asthma, J Allergy Clin Immunol 2011; 128:549-56 e1-12.
-
(2011)
J Allergy Clin Immunol
, vol.128
, pp. 549-556
-
-
Xiao, C.1
Puddicombe, S.M.2
Fields3
Haywood, J.4
Broughton-Head, V.5
Puxeddu, I.6
-
71
-
-
0030778321
-
Airway epithelial repair: Breathtakingly quick and multipotentially pathogenic
-
Erjefalt JS, Persson CG. Airway epithelial repair: breathtakingly quick and multipotentially pathogenic. Thorax 1997; 52:1010-2.
-
(1997)
Thorax
, vol.52
, pp. 1010-1012
-
-
Erjefalt, J.S.1
Persson, C.G.2
-
72
-
-
0033977013
-
Epithelial-mesenchymal interactions in the pathogenesis of asthma
-
Holgate ST, Davies DE, Lackie P.M., Wilson SJ, Puddicombe SM, Lordan JL Epithelial-mesenchymal interactions in the pathogenesis of asthma. J Allergy Clin Immunol 2000; 105:193-204.
-
(2000)
J Allergy Clin Immunol
, vol.105
, pp. 193-204
-
-
Holgate, S.T.1
Davies, D.E.2
Lackie, P.M.3
Wilson, S.J.4
Puddicombe, S.M.5
Lordan, J.L.6
-
73
-
-
0033923224
-
Involvement of the epidermal growth factor receptor in epithelial repair in asthma
-
Puddicombe SM, Polosa R, Richter A., Krishna MT, Howarth PH, Holgate ST, et al. Involvement of the epidermal growth factor receptor in epithelial repair in asthma. EASES J 2000; 14:1362-74.
-
(2000)
EASES J
, vol.14
, pp. 1362-1374
-
-
Puddicombe, S.M.1
Polosa, R.2
Richter, A.3
Krishna, M.T.4
Howarth, P.H.5
Holgate, S.T.6
-
74
-
-
0031156745
-
Myofibroblast involvement in the allergen-induced late response in mild atopic asthma
-
Gizycki MJ, Adelroth E, Rogers A.V., O'Byrne PM, Jeffery PK. Myofibroblast involvement in the allergen-induced late response in mild atopic asthma. Am J Respir Cell Mol Biol 1997; 16:664-73.
-
(1997)
Am J Respir Cell Mol Biol
, vol.16
, pp. 664-673
-
-
Gizycki, M.J.1
Adelroth, E.2
Rogers, A.V.3
O'Byrne, P.M.4
Jeffery, P.K.5
-
75
-
-
84863393701
-
Pediatric severeasthma is characterized byeosinophiliaand remodeling without T(H)2 cytokimes
-
el3
-
Bossley CJ, Fleming L, Gupta A., Regamey N, Frith J, Oates T., et al. Pediatric severeasthma is characterized byeosinophiliaand remodeling without T(H)2 cytokimes. J Allergy Clin Immunol 2012; 129:974-82 el3.
-
(2012)
J Allergy Clin Immunol
, vol.129
, pp. 974-982
-
-
Bossley, C.J.1
Fleming, L.2
Gupta, A.3
Regamey, N.4
Frith, J.5
Oates, T.6
-
76
-
-
82555185032
-
Relationship between past airway pathology and current lung function in preschool wheezers
-
Sonnappa S, Bastardo CM, Saglani S, Bush A., Aurora R Relationship between past airway pathology and current lung function in preschool wheezers. Eur Respir J 2011; 38:1431-6.
-
(2011)
Eur Respir J
, vol.38
, pp. 1431-1436
-
-
Sonnappa, S.1
Bastardo, C.M.2
Saglani, S.3
Bush, A.4
Aurora, R.5
-
77
-
-
0033694849
-
Unsuspected pseudophysiologic emphysema in chronic persistent asthma
-
Gelb AF, Zamel N. Unsuspected pseudophysiologic emphysema in chronic persistent asthma. Am J Respir Crit Care Med 2000; 162:1778-82.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 1778-1782
-
-
Gelb, A.F.1
Zamel, N.2
-
78
-
-
79957512933
-
Effect of bronchoconstriction on airway remodeling in asthma
-
Grainge CL, Lau LC, Ward J.A., Dulay V., Lahiff G, Wilson S, et al. Effect of bronchoconstriction on airway remodeling in asthma. N Engl J Med 2011; 364:2006-15.
-
(2011)
N Engl J Med
, vol.364
, pp. 2006-2015
-
-
Grainge, C.L.1
Lau, L.C.2
Ward, J.A.3
Dulay, V.4
Lahiff, G.5
Wilson, S.6
-
79
-
-
84878580085
-
Airway smooth muscle in the pathophysiology and treatment of asthma
-
Doeing DC, Solway J. Airway smooth muscle in the pathophysiology and treatment of asthma, J Appl Physiol (1985) 2013; 114:834-43.
-
(2013)
J Appl Physiol (1985)
, vol.114
, pp. 834-843
-
-
Doeing, D.C.1
Solway, J.2
-
80
-
-
0029915964
-
PDGF isoform-induced proliferation and receptor expression in human cultured airway smooth muscle cells
-
Hirst SJ, Barnes PJ, Twort CH. PDGF isoform-induced proliferation and receptor expression in human cultured airway smooth muscle cells. Am J Physiol 1996; 270(3 Pt 1):L415-28.
-
(1996)
Am J Physiol
, vol.270
, Issue.3
, pp. L415-28
-
-
Hirst, S.J.1
Barnes, P.J.2
Twort, C.H.3
-
82
-
-
0030689729
-
Induction of airway mucus production by thelper 2 (Th 2) cells: A critical role for interleukin 4 in cell recruitment but not mucus production
-
Cohn L, Homer RJ, Marinov A, Rankin J., Bottomly K. Induction of airway mucus production by Thelper 2 (Th 2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J Exp Med 1997; 186:1737-47.
-
(1997)
J Exp Med
, vol.186
, pp. 1737-1747
-
-
Cohn, L.1
Homer, R.J.2
Marinov, A.3
Rankin, J.4
Bottomly, K.5
-
83
-
-
17444454662
-
Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma
-
Lee JJ, McGarry MP, Farmer S.C., Denzler KL, Larson KA, Carrigan PE, et al Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma, J Exp Med 1997; 185:2143-56.
-
(1997)
J Exp Med
, vol.185
, pp. 2143-2156
-
-
Lee, J.J.1
McGarry, M.P.2
Farmer, S.C.3
Denzler, K.L.4
Larson, K.A.5
Carrigan, P.E.6
-
84
-
-
32444436464
-
Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals
-
Tyner JW, Kim EY, Ide K, Pelletier MR, Roswit WT, Morton JD, et al. Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals.; Clin Invest 2006; 116:309-21.
-
(2006)
Clin Invest
, vol.116
, pp. 309-321
-
-
Tyner, J.W.1
Kim, E.Y.2
Ide, K.3
Pelletier, M.R.4
Roswit, W.T.5
Morton, J.D.6
-
85
-
-
65749114825
-
The role of CLCA proteins in inflammatory airway disease
-
Patel AC, Brett TJ, Holtzman MJ. The role of CLCA proteins in inflammatory airway disease. Annu Rev Physiol 2009; 71:425-49.
-
(2009)
Annu Rev Physiol
, vol.71
, pp. 425-449
-
-
Patel, A.C.1
Brett, T.J.2
Holtzman, M.J.3
-
86
-
-
79959344460
-
Expert Panel Report 3 (EPR-3). Guidelines for the diagnosis and management of asthma-summary report 2007
-
Expert Panel Report 3 (EPR-3). Guidelines for the diagnosis and management of asthma-summary report 2007. J Allergy Clin Immunol 2007; 120(5 suppl):S94-138.
-
(2007)
J Allergy Clin Immunol
, vol.120
, Issue.5
, pp. S94-138
-
-
-
88
-
-
77949576423
-
Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids
-
Lemanske RF Jr., Mauger DT, Sorkness C.A., Jackson DJ, Boehmer SJ, Martinez FD, et al. Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids. N Engl J Med 2010; 362:975-85.
-
(2010)
N Engl J Med
, vol.362
, pp. 975-985
-
-
Lemanske, R.F.1
Mauger, D.T.2
Sorkness, C.A.3
Jackson, D.J.4
Boehmer, S.J.5
Martinez, F.D.6
-
89
-
-
43949129790
-
Montelukast as add-on therapy to inhaled corticosteroids in the treatment of mild to moderate asthma: A systematic review
-
Joos S, Miksch A, Szecsenyi J., Wieseler B, Grouven U, Kaiser T., et al. Montelukast as add-on therapy to inhaled corticosteroids in the treatment of mild to moderate asthma: a systematic review. Thorax 2008; 63:453-62.
-
(2008)
Thorax
, vol.63
, pp. 453-462
-
-
Joos, S.1
Miksch, A.2
Szecsenyi, J.3
Wieseler, B.4
Grouven, U.5
Kaiser, T.6
-
90
-
-
77957768543
-
Tiotropium bromide step-up therapy for adults with uncontrolled asthma
-
Peters SR Kunselman SJ, Icitovic N, Moore W.C., Pascual R., Ameredes BT, et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med 2010; 363:1715-26.
-
(2010)
N Engl J Med
, vol.363
, pp. 1715-1726
-
-
Peters, S.R.1
Kunselman, S.J.2
Icitovic, N.3
Moore, W.C.4
Pascual, R.5
Ameredes, B.T.6
-
91
-
-
84866758536
-
Tiotropium in asthma poorly controlled with standard combination therapy
-
Kerstjens HA, Engel M, Dahl R., Paggiaro R Beck E, Vandewalker M, et al. Tiotropium in asthma poorly controlled with standard combination therapy. N Engl J Med 2012; 367:1198-207.
-
(2012)
N Engl J Med
, vol.367
, pp. 1198-1207
-
-
Kerstjens, H.A.1
Engel, M.2
Dahl, R.3
Paggiaro, R.4
Beck, E.5
Vandewalker, M.6
-
92
-
-
84903816429
-
Omalizumab for asthma in adults and children
-
Normansell R, Walker S, Milan S.J., Walters EH, Nair P. Omalizumab for asthma in adults and children. Cochrane Database Syst Rev 2014; 1: CD003559.
-
(2014)
Cochrane Database Syst Rev
, vol.1
-
-
Normansell, R.1
Walker, S.2
Milan, S.J.3
Walters, E.H.4
Nair, P.5
-
93
-
-
84867292926
-
Omalizumab for the treatment of severe persistent allergic asthma in children aged 6-11 years: A NICE single technology appraisal
-
Burch J, Griffin S, McKenna C., Walker S, Paton J, Wright K., et al. Omalizumab for the treatment of severe persistent allergic asthma in children aged 6-11 years: a NICE single technology appraisal Pharmacoeconomics 2012; 30:991-1004.
-
(2012)
Pharmacoeconomics
, vol.30
, pp. 991-1004
-
-
Burch, J.1
Griffin, S.2
McKenna, C.3
Walker, S.4
Paton, J.5
Wright, K.6
-
94
-
-
6444236644
-
Radiofrequency ablation of airway smooth muscle for sustained treatment of asthma: Preliminary investigations
-
Cox PG, Miller J, Mitzner W Leff AR. Radiofrequency ablation of airway smooth muscle for sustained treatment of asthma: preliminary investigations. Eur Respir J 2004; 24:659-63.
-
(2004)
Eur Respir J
, vol.24
, pp. 659-663
-
-
Cox, P.G.1
Miller, J.2
Mitzner, W.3
Leff, A.R.4
-
95
-
-
34047099762
-
Asthma control during the year after bronchial thermoplasty
-
Cox G, Thomson NC, Rubin A.S., Niven RM, Corris PA, Siersted HC, et al. Asthma control during the year after bronchial thermoplasty. N Engl J Med 2007; 356:1327-37.
-
(2007)
N Engl J Med
, vol.356
, pp. 1327-1337
-
-
Cox, G.1
Thomson, N.C.2
Rubin, A.S.3
Niven, R.M.4
Corris, P.A.5
Siersted, H.C.6
-
96
-
-
84888595710
-
Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma
-
Wechsler ME, Laviolette M, Rubin A.S., Fiterman J., Lapae Silva JR, Shah PL, et al. Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma. J Allergy Clin Immunol 2013; 132:1295-302.
-
(2013)
J Allergy Clin Immunol
, vol.132
, pp. 1295-1302
-
-
Wechsler, M.E.1
Laviolette, M.2
Rubin, A.S.3
Fiterman, J.4
Lapae Silva, J.R.5
Shah, P.L.6
-
97
-
-
80055080781
-
New insights into the natural history of asthma: Primary prevention on the horizon
-
Martinez FD. New insights into the natural history of asthma: primary prevention on the horizon. J Allergy Clin Immunol 2011; 128:939-45.
-
(2011)
J Allergy Clin Immunol
, vol.128
, pp. 939-945
-
-
Martinez, F.D.1
-
98
-
-
33646488054
-
Long-term inhaled corticosteroids in preschool children at high risk for asthma
-
Guilbert TW Morgan WJ, Zeiger RS, Mauger D.T., Boehmer SJ, Szefler SJ, et al. Long-term inhaled corticosteroids in preschool children at high risk for asthma. N Engl J Med 2006; 354:1985-97.
-
(2006)
N Engl J Med
, vol.354
, pp. 1985-1997
-
-
Guilbert, T.W.1
Morgan, W.J.2
Zeiger, R.S.3
Mauger, D.T.4
Boehmer, S.J.5
Szefler, S.J.6
-
99
-
-
38049121369
-
Airway modeling and remodeling in the pathogenesis of asthma
-
Warner SM, Knight DA. Airway modeling and remodeling in the pathogenesis of asthma. Curr Opin Allergy Clin Immunol 2008; 8:44-8.
-
(2008)
Curr Opin Allergy Clin Immunol
, vol.8
, pp. 44-48
-
-
Warner, S.M.1
Knight, D.A.2
-
100
-
-
84883218243
-
IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma
-
el3.
-
Saglani S, Lui S, Ullmann N., Campbell GA, Sherburn RT, Mathie SA, et al IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma. J Allergy Clin Immunol 2013; 132:676-85 el3.
-
(2013)
J Allergy Clin Immunol
, vol.132
, pp. 676-685
-
-
Saglani, S.1
Lui, S.2
Ullmann, N.3
Campbell, G.A.4
Sherburn, R.T.5
Mathie, S.A.6
-
101
-
-
0034523602
-
Clinical management of asthma in 1999: The asthma insights and reality in europe (AIRE) study
-
Rabe KF, Vermeire PA, Soriano J.B., Maier WC. Clinical management of asthma in 1999: the Asthma Insights and Reality in Europe (AIRE) study. Eur Respir J 2000;16:802-7.
-
(2000)
Eur Respir J
, vol.16
, pp. 802-807
-
-
Rabe, K.F.1
Vermeire, P.A.2
Soriano, J.B.3
Maier, W.C.4
-
102
-
-
33745596102
-
Attitudes and actions of asthma patients on regular maintenance therapy: The INSPIRE study
-
Partridge MR, van der Molen T, Myrseth SE, Busse WW. Attitudes and actions of asthma patients on regular maintenance therapy: the INSPIRE study. BMC Pulmon Med 2006; 6:13.
-
(2006)
BMC Pulmon Med
, vol.6
, pp. 13
-
-
Partridge, M.R.1
Van Der Molen, T.2
Myrseth, S.E.3
Busse, W.W.4
-
103
-
-
33846017302
-
Severe asthma: Lessons from the severe asthma research program
-
quiz 22-3
-
Wenzel SE, Busse WW. Severe asthma: lessons from the severe asthma research program. J Allergy Clin Immunol 2007;119:14-21; quiz 22-3.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 14-21
-
-
Wenzel, S.E.1
Busse, W.W.2
-
104
-
-
0032409133
-
Costs of asthma according to the degree of severity
-
Serra-Batlles J., Plaza V, Morejon E., Comella A, Brugues J. Costs of asthma according to the degree of severity. Eur Respir J 1998; 12:1322-6.
-
(1998)
Eur Respir J
, vol.12
, pp. 1322-1326
-
-
Serra-Batlles, J.1
Plaza, V.2
Morejon, E.3
Comella, A.4
Brugues, J.5
-
105
-
-
0028274731
-
Patient compliance with inhaled medication: Does combining beta-agonists with corticosteroids improve compliance?
-
Bosley CM, Parry DT, Cochrane GM Patient compliance with inhaled medication: does combining beta-agonists with corticosteroids improve compliance? Eur Respir J 1994; 7:504-9.
-
(1994)
Eur Respir J
, vol.7
, pp. 504-509
-
-
Bosley, C.M.1
Parry, D.T.2
Cochrane, G.M.3
-
106
-
-
84865687594
-
Effect of inhaled glucocorticoids in childhood on adult height
-
Kelly HW, Sternberg AL, Lescher R, Fuhlbrigge A.L., Williams P., Zeiger RS, et al. Effect of inhaled glucocorticoids in childhood on adult height. N Engl J Med 2012; 367:904-12.
-
(2012)
N Engl J Med
, vol.367
, pp. 904-912
-
-
Kelly, H.W.1
Sternberg, A.L.2
Lescher, R.3
Fuhlbrigge, A.L.4
Williams, P.5
Zeiger, R.S.6
-
107
-
-
0033542041
-
Systemic adverse effects of inhaled corticosteroid therapy: A systematic review and meta-analysis
-
Lipworth BJ. Systemic adverse effects of inhaled corticosteroid therapy: a systematic review and meta-analysis. Arch Intern Med 1999; 159:941-55.
-
(1999)
Arch Intern Med
, vol.159
, pp. 941-955
-
-
Lipworth, B.J.1
-
108
-
-
33144476873
-
The salmeterol multicenter asthma research trial: A comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol
-
Nelson HS, Weiss ST, Bleecker E.R., Yancey SW Dorinsky PM. The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest 2006; 129:15-26.
-
(2006)
Chest
, vol.129
, pp. 15-26
-
-
Nelson, H.S.1
Weiss, S.T.2
Bleecker, E.R.3
Yancey, S.W.4
Dorinsky, P.M.5
-
109
-
-
70449724793
-
Reports of suicidality in clinical trials of Montelukast
-
e6.
-
Philip G, Hustad C, Noonan G., Malice MP, Ezekowitz A, Reiss TF, et al Reports of suicidality in clinical trials of montelukast. J Allergy Clin Immunol 2009; 124:691-6 e6.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 691-696
-
-
Philip, G.1
Hustad, C.2
Noonan, G.3
Malice, M.P.4
Ezekowitz, A.5
Reiss, T.F.6
-
110
-
-
70449704180
-
Analysis of behavior-related adverse experiences in clinical trials of Montelukast
-
e8.
-
Philip G, Hustad CM, Malice M.P., Noonan G., Ezekowitz A, Reiss TF, et al Analysis of behavior-related adverse experiences in clinical trials of montelukast J Allergy Clin Immunol 2009; 124:699-706 e8.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 699-706
-
-
Philip, G.1
Hustad, C.M.2
Malice, M.P.3
Noonan, G.4
Ezekowitz, A.5
Reiss, T.F.6
-
111
-
-
70349337022
-
24-hour bronchodilator efficacy of single doses of indacaterol in patients with persistent asthma: Comparison with placebo and formoterol
-
LaForce C, Korenblat P, Osborne P., Dong F, Higgins M. 24-hour bronchodilator efficacy of single doses of indacaterol in patients with persistent asthma: comparison with placebo and formoterol. Curr Med Res Opin 2009; 25:2353-9.
-
(2009)
Curr Med Res Opin
, vol.25
, pp. 2353-2359
-
-
LaForce, C.1
Korenblat, P.2
Osborne, P.3
Dong, F.4
Higgins, M.5
-
112
-
-
47349093973
-
Bronchodilator efficacy of indacaterol, a novel once-daily beta2-agonist, in patients with persistent asthma
-
Pearlman DS, Greos L, LaForce C., Orevillo CJ, Owen R, Higgins M. Bronchodilator efficacy of indacaterol, a novel once-daily beta2-agonist, in patients with persistent asthma. Ann Allergy Asthma Immunol 2008; 101:90-5.
-
(2008)
Ann Allergy Asthma Immunol
, vol.101
, pp. 90-95
-
-
Pearlman, D.S.1
Greos, L.2
LaForce, C.3
Orevillo, C.J.4
Owen, R.5
Higgins, M.6
-
113
-
-
84885152829
-
Efficacy and safety of fluticasone furoate/vilanterol compared with fluticasone propionate/salmeterol combination in adult and adolescent patients with persistent asthma: A randomized trial
-
Woodcock A Bleecker ER, Lotvall J, O'Byrne PM, Bateman ED, Medley H, et al. Efficacy and safety of fluticasone furoate/vilanterol compared with fluticasone propionate/salmeterol combination in adult and adolescent patients with persistent asthma: a randomized trial. Chest 2013; 144:1222-9.
-
(2013)
Chest
, vol.144
, pp. 1222-1229
-
-
Woodcock, A.1
Bleecker, E.R.2
Lotvall, J.3
O'Byrne, P.M.4
Bateman, E.D.5
Medley, H.6
-
114
-
-
84859390611
-
A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma
-
Reber LL, Daubeuf F Plantinga M, De Cauwer L, Gerlo S, Waelput W, et al. A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma. J Immunol 2012; 188:3478-87.
-
(2012)
J Immunol
, vol.188
, pp. 3478-3487
-
-
Reber, L.L.1
Daubeuf, F.2
Plantinga, M.3
De Cauwer, L.4
Gerlo, S.5
Waelput, W.6
-
115
-
-
65849427529
-
Glucocorticoid resistance in inflammatory diseases
-
Barnes PJ, Adcock IM. Glucocorticoid resistance in inflammatory diseases. Lancet 2009; 373:1905-17.
-
(2009)
Lancet
, vol.373
, pp. 1905-1917
-
-
Barnes, P.J.1
Adcock, I.M.2
-
116
-
-
84901770303
-
Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma
-
el
-
Zhang Y, Leung DY Goleva E. Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma J Allergy Clin Immunol 2014; 133:1744-52. el.
-
(2014)
J Allergy Clin Immunol
, vol.133
, pp. 1744-1752
-
-
Zhang, Y.1
Leung, D.Y.2
Goleva, E.3
-
117
-
-
0030003887
-
Interleukin-5 messenger RNA expression in peripheral blood CD4+ cells in asthma
-
Lai CK, Ho AS, Chan C.H., Tang J., Leung JC, Lai KN. Interleukin-5 messenger RNA expression in peripheral blood CD4+ cells in asthma J Allergy Clin Immunol 1996; 97:1320-8.
-
(1996)
J Allergy Clin Immunol
, vol.97
, pp. 1320-1328
-
-
Lai, C.K.1
Ho, A.S.2
Chan, C.H.3
Tang, J.4
Leung, J.C.5
Lai, K.N.6
-
118
-
-
0025760379
-
Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma
-
Hamid Q, Azzawi M, Ying S., Moqbel R, Wardlaw AJ, Corrigan C.J., et al. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin Invest 1991; 87:1541-6.
-
(1991)
J Clin Invest
, vol.87
, pp. 1541-1546
-
-
Hamid, Q.1
Azzawi, M.2
Ying, S.3
Moqbel, R.4
Wardlaw, A.J.5
Corrigan, C.J.6
-
119
-
-
0029302202
-
Phenotype of cells expressing mRNA for TH 2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects
-
Ying S, Durham SR, Corrigan C.J., Hamid Q., Kay AB. Phenotype of cells expressing mRNA for TH 2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects. Am J Respir Cell Mol Biol 1995; 12:477-87.
-
(1995)
Am J Respir Cell Mol Biol
, vol.12
, pp. 477-487
-
-
Ying, S.1
Durham, S.R.2
Corrigan, C.J.3
Hamid, Q.4
Kay, A.B.5
-
120
-
-
35748932380
-
Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation
-
Sakuishi K, Oki S, Araki M., Porcelli SA, Miyake S, Yamamura T. Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation. J Immunol 2007; 179:3452-62.
-
(2007)
J Immunol
, vol.179
, pp. 3452-3462
-
-
Sakuishi, K.1
Oki, S.2
Araki, M.3
Porcelli, S.A.4
Miyake, S.5
Yamamura, T.6
-
121
-
-
0027979447
-
Interleukin 5 synthesis by eosinophils: Association with granules and immunoglobulin-dependent secretion
-
Dubucquoi S, Desreumaux P, Janin A., Klein O, Goldman M, Tavernier J., et al. Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. J Exp Med 1994; 179:703-8.
-
(1994)
J Exp Med
, vol.179
, pp. 703-708
-
-
Dubucquoi, S.1
Desreumaux, P.2
Janin, A.3
Klein, O.4
Goldman, M.5
Tavernier, J.6
-
122
-
-
0037239495
-
Basophils express a type 2 cytokine profile on exposure to proteases from helminths and house dust mites
-
Phillips C, Coward WR, Pritchard D.I., Hewitt CR. Basophils express a type 2 cytokine profile on exposure to proteases from helminths and house dust mites. J Leukoc Biol 2003; 73:165-71.
-
(2003)
J Leukoc Biol
, vol.73
, pp. 165-171
-
-
Phillips, C.1
Coward, W.R.2
Pritchard, D.I.3
Hewitt, C.R.4
-
123
-
-
0030831869
-
Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation
-
Sehmi R, Wood LJ, Watson R, Foley R., Hamid Q, O'Byrne PM, et al. Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation. J Clin Invest 1997; 100:2466-75.
-
(1997)
J Clin Invest
, vol.100
, pp. 2466-2475
-
-
Sehmi, R.1
Wood, L.J.2
Watson, R.3
Foley, R.4
Hamid, Q.5
O'Byrne, P.M.6
-
124
-
-
84860010929
-
Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor
-
Molfino NA, Gossage D, Kolbeck R., Parker JM, Geba GP. Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor. Clin Exp Allergy 2012; 42:712-37.
-
(2012)
Clin Exp Allergy
, vol.42
, pp. 712-737
-
-
Molfino, N.A.1
Gossage, D.2
Kolbeck, R.3
Parker, J.M.4
Geba, G.P.5
-
125
-
-
1542314903
-
Regulation of bone marrow and airway CD34+ eosinophils by interleukin-5
-
Sitkauskiene B, Johansson AK, Sergejeva S, Lundin S., Sjostrand M, Lotvall J. Regulation of bone marrow and airway CD34+ eosinophils by interleukin-5. Am J Respir Cell Mol Biol 2004; 30:367-78.
-
(2004)
Am J Respir Cell Mol Biol
, vol.30
, pp. 367-378
-
-
Sitkauskiene, B.1
Johansson, A.K.2
Sergejeva, S.3
Lundin, S.4
Sjostrand, M.5
Lotvall, J.6
-
126
-
-
9244240963
-
Allergen-induced traffic of bone marrow eosinophils, neutrophils and lymphocytes to airways
-
Johansson AK, Sergejeva S, Sjostrand M., Lee JJ, Lotvall J. Allergen-induced traffic of bone marrow eosinophils, neutrophils and lymphocytes to airways. Eur J Immunol 2004; 34:3135-45.
-
(2004)
Eur J Immunol
, vol.34
, pp. 3135-3145
-
-
Johansson, A.K.1
Sergejeva, S.2
Sjostrand, M.3
Lee, J.J.4
Lotvall, J.5
-
127
-
-
0031014771
-
IL-5 but not interferon-gamma (IFN-gamma) inhibits eosinophil apoptosis by up-regulation of bcl-2 expression
-
Ochiai K, Kagami M, Matsumura R., Tomioka H. IL-5 but not interferon-gamma (IFN-gamma) inhibits eosinophil apoptosis by up-regulation of bcl-2 expression. Clin Exp Immunol 1997; 107:198-204.
-
(1997)
Clin Exp Immunol
, vol.107
, pp. 198-204
-
-
Ochiai, K.1
Kagami, M.2
Matsumura, R.3
Tomioka, H.4
-
128
-
-
68349130434
-
Haemopoietic processes in allergic disease: Eosinophil/basophil development
-
Gauvreau GM, Ellis AK, Denburg JA. Haemopoietic processes in allergic disease: eosinophil/basophil development. Clin Exp Allergy 2009; 39:1297-306.
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 1297-1306
-
-
Gauvreau, G.M.1
Ellis, A.K.2
Denburg, J.A.3
-
129
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
-
Leckie MJ, ten Brinke A, Khan J, Diamant Z., O'Connor BJ, Walls CM, et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 2000; 356:2144-8.
-
(2000)
Lancet
, vol.356
, pp. 2144-2148
-
-
Leckie, M.J.1
Ten Brinke, A.2
Khan, J.3
Diamant, Z.4
O'Connor, B.J.5
Walls, C.M.6
-
130
-
-
36749065556
-
A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma
-
Flood-Page P., Swenson C, Faiferman I., Matthews J, Williams M, Brannick L., et al. A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma. Am J Respir Crit Care Med 2007; 176:1062-71.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 1062-1071
-
-
Flood-Page, P.1
Swenson, C.2
Faiferman, I.3
Matthews, J.4
Williams, M.5
Brannick, L.6
-
131
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar P, Brightling CE, Hargadon B, Gupta S., Monteiro W, Sousa A, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009; 360:973-84.
-
(2009)
N Engl J Med
, vol.360
, pp. 973-984
-
-
Haldar, P.1
Brightling, C.E.2
Hargadon, B.3
Gupta, S.4
Monteiro, W.5
Sousa, A.6
-
132
-
-
61849155730
-
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
-
Nair P, Pizzichini MM, Kjarsgaard M, Inman M.D., Efthimiadis A., Pizzichini E, et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med 2009; 360:985-93.
-
(2009)
N Engl J Med
, vol.360
, pp. 985-993
-
-
Nair, P.1
Pizzichini, M.M.2
Kjarsgaard, M.3
Inman, M.D.4
Efthimiadis, A.5
Pizzichini, E.6
-
133
-
-
84865145614
-
Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
-
Pavord ID, Korn S, Howarth P., Bleecker ER, Buhl R, Keene ON, et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet 2012; 380:651-9.
-
(2012)
Lancet
, vol.380
, pp. 651-659
-
-
Pavord, I.D.1
Korn, S.2
Howarth, P.3
Bleecker, E.R.4
Buhl, R.5
Keene, O.N.6
-
134
-
-
81455155725
-
Reslizumab for poorly controlled, eosinophilic asthma: A randomized, placebo-controlled study
-
Castro M, Mathur S, Hargreave F Boulet LP, Xie F Young J, et al. Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am J Respir Crit Care Med 2011; 184: 1125-32.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 1125-1132
-
-
Castro, M.1
Mathur, S.2
Hargreave, F.3
Boulet, L.P.4
Xie, F.5
Young, J.6
-
135
-
-
77952683218
-
Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma
-
e2.
-
Busse WW, Katial R, Gossage D., Sari S, Wang B, Kolbeck R., et al. Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma. J Allergy Clin Immunol 2010; 125:1237-44.e2.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 1237-1244
-
-
Busse, W.W.1
Katial, R.2
Gossage, D.3
Sari, S.4
Wang, B.5
Kolbeck, R.6
-
136
-
-
84887020563
-
Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia
-
e5.
-
Laviolette M, Gossage DL, Gauvreau G, Leigh R., Olivenstein R, Katial R, et al Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia. J Allergy Clin Immunol 2013; 132: 1086-96.e5.
-
(2013)
J Allergy Clin Immunol
, vol.132
, pp. 1086-1096
-
-
Laviolette, M.1
Gossage, D.L.2
Gauvreau, G.3
Leigh, R.4
Olivenstein, R.5
Katial, R.6
-
137
-
-
20444423863
-
IgE generation and mast cell effector function in mice deficient in IL-4 and IL-13
-
Fish SC, Donaldson DD, Goldman S.J., Williams CM, Kasaian MT IgE generation and mast cell effector function in mice deficient in IL-4 and IL-13. J Immunol 2005;174:7716-24.
-
(2005)
J Immunol
, vol.174
, pp. 7716-7724
-
-
Fish, S.C.1
Donaldson, D.D.2
Goldman, S.J.3
Williams, C.M.4
Kasaian, M.T.5
-
138
-
-
0029982434
-
Endobronchial secretion of interleukin-13 following local allergen challenge in atopic asthma: Relationship to interleukin-4 and eosinophil counts
-
Kroegel C, Julius P, Matthys H., Virchow JC Jr, Luttmann W Endobronchial secretion of interleukin-13 following local allergen challenge in atopic asthma: relationship to interleukin-4 and eosinophil counts. Eur Respir J 1996; 9:899-904.
-
(1996)
Eur Respir J
, vol.9
, pp. 899-904
-
-
Kroegel, C.1
Julius, P.2
Matthys, H.3
Virchow, J.C.4
Luttmann, W.5
-
139
-
-
0037308329
-
The role of the mast cell in asthma: A reassessment
-
Bradding P. The role of the mast cell in asthma: a reassessment. Curr Opin Allergy Clin Immunol 2003; 3:45-50.
-
(2003)
Curr Opin Allergy Clin Immunol
, vol.3
, pp. 45-50
-
-
Bradding, P.1
-
140
-
-
0029038120
-
IL-13 expression at the sites of allergen challenge in patients with asthma
-
Huang SK, Xiao HQ, Kleine-Tebbe J, Paciotti G., Marsh DG, Lichtenstein LM, et al. IL-13 expression at the sites of allergen challenge in patients with asthma. J Immunol 1995; 155:2688-94.
-
(1995)
J Immunol
, vol.155
, pp. 2688-2694
-
-
Huang, S.K.1
Xiao, H.Q.2
Kleine-Tebbe, J.3
Paciotti, G.4
Marsh, D.G.5
Lichtenstein, L.M.6
-
142
-
-
0037100414
-
Eosinophils express functional IL-13 in eosinophilic inflammatory diseases
-
Schmid-Grendelmeier P., Altznauer F Fischer B, Bizer C, Straumann A, Menz G, et al. Eosinophils express functional IL-13 in eosinophilic inflammatory diseases. J Immunol 2002; 169:1021-7.
-
(2002)
J Immunol
, vol.169
, pp. 1021-1027
-
-
Schmid-Grendelmeier, P.1
Altznauer, F.2
Fischer, B.3
Bizer, C.4
Straumann, A.5
Menz, G.6
-
143
-
-
0029975243
-
IL-13 released by and localized in human basophils
-
Li H, Sim TC, Alam R. IL-13 released by and localized in human basophils. J Immunol 1996; 156:4833-8.
-
(1996)
J Immunol
, vol.156
, pp. 4833-4838
-
-
Li, H.1
Sim, T.C.2
Alam, R.3
-
144
-
-
0037064548
-
Structure, binding, and antagonists in the IL-4/IL-13 receptor system
-
Mueller TD, Zhang JL, Sebald W Duschl A. Structure, binding, and antagonists in the IL-4/IL-13 receptor system. Biochim Biophys Acta 2002; 1592:237-50.
-
(2002)
Biochim Biophys Acta
, vol.1592
, pp. 237-250
-
-
Mueller, T.D.1
Zhang, J.L.2
Sebald, W.3
Duschl, A.4
-
145
-
-
0030844646
-
Interleukin-13 selectively induces monocyte chemoattractant protein-1 synthesis and secretion by human endothelial cells. Involvement of IL-4R alpha and stat6 phosphorylation
-
Goebeler M, Schnarr B, Toksoy A., Kunz M, Brocker EB, Duschl A, et al. Interleukin-13 selectively induces monocyte chemoattractant protein-1 synthesis and secretion by human endothelial cells. Involvement of IL-4R alpha and Stat6 phosphorylation. Immunology 1997; 91:450-7.
-
(1997)
Immunology
, vol.91
, pp. 450-457
-
-
Goebeler, M.1
Schnarr, B.2
Toksoy, A.3
Kunz, M.4
Brocker, E.B.5
Duschl, A.6
-
146
-
-
0142197612
-
Regulation of IL4 gene expression by T cells and therapeutic perspectives
-
Li-Weber M., Krammer PH. Regulation of IL4 gene expression by T cells and therapeutic perspectives. Nat Rev Immunol 2003; 3:534-43.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 534-543
-
-
Li-Weber, M.1
Krammer, P.H.2
-
147
-
-
0037393323
-
IL-13 receptors and signaling pathways: An evolving web
-
quiz 91.
-
Hershey GK. IL-13 receptors and signaling pathways: an evolving web. J Allergy Clin Immunol 2003; 111:677-90; quiz 91.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 677-690
-
-
Hershey, G.K.1
-
148
-
-
0033454115
-
Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial
-
Borish LC, Nelson HS, Lanz M.J., Claussen L., Whitmore JB, Agosti JM, et al. Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial. Am J Respir Crit Care Med 1999; 160:1816-23.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1816-1823
-
-
Borish, L.C.1
Nelson, H.S.2
Lanz, M.J.3
Claussen, L.4
Whitmore, J.B.5
Agosti, J.M.6
-
149
-
-
0034995872
-
Efficacy of soluble IL-4receptor for the treatment of adults with asthma
-
Borish LC, Nelson HS, Corren J, Bensch G., Busse WW, Whitmore JB, et al. Efficacy of soluble IL-4receptor for the treatment of adults with asthma. J Allergy Clin Immunol 2001; 107:963-70.
-
(2001)
J Allergy Clin Immunol
, vol.107
, pp. 963-970
-
-
Borish, L.C.1
Nelson, H.S.2
Corren, J.3
Bensch, G.4
Busse, W.W.5
Whitmore, J.B.6
-
150
-
-
77953039047
-
A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma
-
Corren J, Busse W Meltzer EO, Mansfield L, Bensch G, Fahrenholz J, et al. A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma. Am J Respir Crit Care Med 2010; 181:788-96.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 788-796
-
-
Corren, J.1
Busse, W.2
Meltzer, E.O.3
Mansfield, L.4
Bensch, G.5
Fahrenholz, J.6
-
151
-
-
84879401471
-
Dupilumab in persistent asthma with elevated eosinophil levels
-
Wenzel S, Ford L, Pearlman D., Spector S, Sher L, Skobieranda F et al. Dupilumab in persistent asthma with elevated eosinophil levels. N Engl J Med 2013; 368:2455-66.
-
(2013)
N Engl J Med
, vol.368
, pp. 2455-2466
-
-
Wenzel, S.1
Ford, L.2
Pearlman, D.3
Spector, S.4
Sher, L.5
Skobieranda, F.6
-
152
-
-
80053084755
-
Lebrikizumab treatment in adults with asthma
-
Corren J, Lemanske RF Hanania NA, Korenblat PE, Parsey MV, Arron JR, et al. Lebrikizumab treatment in adults with asthma. N Engl J Med 2011; 365:1088-98.
-
(2011)
N Engl J Med
, vol.365
, pp. 1088-1098
-
-
Corren, J.1
Lemanske, R.F.2
Hanania, N.A.3
Korenblat, P.E.4
Parsey, M.V.5
Arron, J.R.6
-
153
-
-
84905389549
-
Th17-associated cytokines as a therapeutic target for steroid-insensitive asthma
-
Morishima Y Ano S, Ishii Y, Ohtsuka S, Matsuyama M, Kawaguchi M, et al. Th17-associated cytokines as a therapeutic target for steroid-insensitive asthma. Clin Dev Immunol 2013; 2013:609395.
-
(2013)
Clin Dev Immunol
, vol.2013
-
-
Morishima, Y.1
Ano, S.2
Ishii, Y.3
Ohtsuka, S.4
Matsuyama, M.5
Kawaguchi, M.6
-
154
-
-
33751180809
-
IL-17 mRNA in sputum of asthmatic patients: Linking T cell driven inflammation and granulocytic influx?
-
Bullens DM, Truyen E, Coteur L., Dilissen E, Hellings PW, Dupont L.J., et al. IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? Respir Res 2006; 7:135.
-
(2006)
Respir Res
, vol.7
, pp. 135
-
-
Bullens, D.M.1
Truyen, E.2
Coteur, L.3
Dilissen, E.4
Hellings, P.W.5
Dupont, L.J.6
-
155
-
-
77953913216
-
Increased serum IL-17 is an independent risk factor for severe asthma
-
Agache I, Ciobanu C, Agache C., Anghel M. Increased serum IL-17 is an independent risk factor for severe asthma. Respir Med 2010; 104: 1131-7.
-
(2010)
Respir Med
, vol.104
, pp. 1131-1137
-
-
Agache, I.1
Ciobanu, C.2
Agache, C.3
Anghel, M.4
-
156
-
-
0034833339
-
IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
-
Molet S, Hamid Q, Davoine F Nutku E, Taha R, Page N, et al. IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol 2001; 108:430-8.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 430-438
-
-
Molet, S.1
Hamid, Q.2
Davoine, F.3
Nutku, E.4
Taha, R.5
Page, N.6
-
157
-
-
84890026323
-
Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma
-
Busse WW, Holgate S, Kerwin E., Chon Y, Feng J, Lin J., et al. Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma. Am J Respir Crit Care Med 2013; 188:1294-302.
-
(2013)
Am J Respir Crit Care Med
, vol.188
, pp. 1294-1302
-
-
Busse, W.W.1
Holgate, S.2
Kerwin, E.3
Chon, Y.4
Feng, J.5
Lin, J.6
-
159
-
-
42949132127
-
Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophi lic responses
-
Gauvreau GM, Boulet LP, Cockcroft D.W., Baatjes A., Cote J, Deschesnes F et al. Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophi lic responses. Am J Respir Crit Care Med 2008; 177:952-8.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 952-958
-
-
Gauvreau, G.M.1
Boulet, L.P.2
Cockcroft, D.W.3
Baatjes, A.4
Cote, J.5
Deschesnes, F.6
-
160
-
-
77951165310
-
SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects
-
Holz O, Khalilieh S, Ludwig-Sengpiel A, Watz H., Stryszak P, Soni P, et al. SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects. Eur Respir J 2010; 35:564-70.
-
(2010)
Eur Respir J
, vol.35
, pp. 564-570
-
-
Holz, O.1
Khalilieh, S.2
Ludwig-Sengpiel, A.3
Watz, H.4
Stryszak, P.5
Soni, P.6
-
161
-
-
84875219804
-
The novel TLR-9 agonist QbG10 shows clinical efficacy in persistent allergic asthma
-
Beeh KM, Kanniess F, Wagner F Schilder C, Naudts I, Hammann-Haenni A, et al. The novel TLR-9 agonist QbG10 shows clinical efficacy in persistent allergic asthma. J Allergy Clin Immunol 2013; 131:866-74.
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 866-874
-
-
Beeh, K.M.1
Kanniess, F.2
Wagner, F.3
Schilder, C.4
Naudts, I.5
Hammann-Haenni, A.6
-
162
-
-
84857053637
-
The potential use of tyrosine kinase inhibitors in severe asthma
-
Guntur VP, Reinero CR The potential use of tyrosine kinase inhibitors in severe asthma. Curr Opin Allergy Clin Immunol 2012; 12:68-75.
-
(2012)
Curr Opin Allergy Clin Immunol
, vol.12
, pp. 68-75
-
-
Guntur, V.P.1
Reinero, C.R.2
-
163
-
-
84876883293
-
Exploring the effects of Omalizumab in allergic asthma: An analysis of biomarkers in the EXTRA study
-
Hanania NA, Wenzel S, Rosen K., Hsieh HJ, Mosesova S, Choy DF et al. Exploring the effects of omalizumab in allergic asthma: an analysis of biomarkers in the EXTRA study. Am J Respir Crit Care Med 2013;187: 804-11.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 804-811
-
-
Hanania, N.A.1
Wenzel, S.2
Rosen, K.3
Hsieh, H.J.4
Mosesova, S.5
Choy, D.F.6
-
164
-
-
77953525965
-
Exhaled nitric oxide predicts control in patients with difficult-to-treat asthma
-
Perez-de-Llano LA, Carballada F Castro Anon O, Pizarro M, Golpe R, Baloira A, et al. Exhaled nitric oxide predicts control in patients with difficult-to-treat asthma. Eur Respir J 2010; 35:1221-7.
-
(2010)
Eur Respir J
, vol.35
, pp. 1221-1227
-
-
Perez-De-Llano, L.A.1
Carballada, F.2
Castro Anon, O.3
Pizarro, M.4
Golpe, R.5
Baloira, A.6
-
165
-
-
84895064176
-
Measures of gene expression in sputum cells can identify T2-high and T2-low subtypes of asthma
-
Peters MC, Mekonnen ZK, Yuan S, Bhakta N.R., Woodruff PG, Fahy JV. Measures of gene expression in sputum cells can identify T2-high and T2-low subtypes of asthma. J Allergy Clin Immunol 2014; 133:388-94.
-
(2014)
J Allergy Clin Immunol
, vol.133
, pp. 388-394
-
-
Peters, M.C.1
Mekonnen, Z.K.2
Yuan, S.3
Bhakta, N.R.4
Woodruff, P.G.5
Fahy, J.V.6
-
166
-
-
6944232728
-
Use of regularly scheduled albuterol treatment in asthma: Genotype-stratified, randomised, placebo-controlled cross-over trial
-
Israel E, Chinchilli VM, Ford J.G., Boushey HA, Cherniack R, Craig TJ, et al. Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet 2004; 364: 1505-12.
-
(2004)
Lancet
, vol.364
, pp. 1505-1512
-
-
Israel, E.1
Chinchilli, V.M.2
Ford, J.G.3
Boushey, H.A.4
Cherniack, R.5
Craig, T.J.6
-
167
-
-
84864445917
-
IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti-IL-4 receptor alpha antagonist
-
e4.
-
Slager RE, Otulana BA, Hawkins G.A., Yen YP, Peters SP, Wenzel SE, et al IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti-IL-4 receptor alpha antagonist J Allergy Clin Immunol 2012; 130:516-22.e4.
-
(2012)
J Allergy Clin Immunol
, vol.130
, pp. 516-522
-
-
Slager, R.E.1
Otulana, B.A.2
Hawkins, G.A.3
Yen, Y.P.4
Peters, S.P.5
Wenzel, S.E.6
-
168
-
-
70449652591
-
Effect of beta 2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): A genotype-stratified, randomised, placebo-controlled, crossover trial
-
Wechsler ME, Kunselman SJ, Chinchilli V.M., Bleecker E., Boushey HA, Calhoun WJ, et al. Effect of beta 2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial. Lancet 2009; 374:1754-64.
-
(2009)
Lancet
, vol.374
, pp. 1754-1764
-
-
Wechsler, M.E.1
Kunselman, S.J.2
Chinchilli, V.M.3
Bleecker, E.4
Boushey, H.A.5
Calhoun, W.J.6
-
169
-
-
84860561692
-
The metabolomics of asthma: Novel diagnostic potential
-
Adamko DJ, Sykes BD, Rowe BH. The metabolomics of asthma: novel diagnostic potential. Chest 2012; 141:1295-302.
-
(2012)
Chest
, vol.141
, pp. 1295-1302
-
-
Adamko, D.J.1
Sykes, B.D.2
Rowe, B.H.3
-
170
-
-
34547557916
-
The use of exhaled nitric oxide to guide asthma management: A randomized controlled trial
-
Shaw DE, Berry MA, Thomas M, Green R.H., Brightling CE, Wardlaw AJ, et al. The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial. Am J Respir Crit Care Med 2007; 176:231-7.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 231-237
-
-
Shaw, D.E.1
Berry, M.A.2
Thomas, M.3
Green, R.H.4
Brightling, C.E.5
Wardlaw, A.J.6
-
171
-
-
0037202790
-
Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial
-
Green RH, Brightling CE, McKenna S, Hargadon B., Parker D, Bradding P, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002; 360:1715-21.
-
(2002)
Lancet
, vol.360
, pp. 1715-1721
-
-
Green, R.H.1
Brightling, C.E.2
McKenna, S.3
Hargadon, B.4
Parker, D.5
Bradding, P.6
|