Endostatin stimulates proliferation and migration of adult rat cardiac fibroblasts through PI3K/Akt pathway

European Journal of Pharmacology

Volumn 750, Issue , 2015, Pages 20-26

  Okada, Muneyoshi ^a   Oba, Yoko ^a   Yamawaki, Hideyuki ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Akt; Cardiac fibroblasts; Endostatin; Migration; Proliferation; Wound healing

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLCYSTEINE; ANTIOXIDANT; COLLAGEN TYPE 1; ENDOSTATIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHARMACOLOGY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

ADULT; ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANTAGONISTS AND INHIBITORS; ARTICLE; BOYDEN CHAMBER ASSAY; CARDIAC FIBROBLAST; CELL ACTIVATION; CELL ASSAY; CELL MIGRATION; CELL MOTION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CYTOLOGY; DRUG EFFECTS; DRUG MECHANISM; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FIBROBLAST; HEART INFARCTION; MALE; METABOLISM; NONHUMAN; PHOSPHORYLATION; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WOUND HEALING; WOUND HEALING ASSAY;

ANIMALS; ANTAGONISTS AND INHIBITORS; ANTIOXIDANTS; CELL MOVEMENT; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; ENDOSTATINS; FIBROBLASTS; MALE; METABOLISM; PHARMACOLOGY; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 84964290466     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.01.019     Document Type: Article

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