Cardiac mesenchymal stem cells contribute to scar formation after myocardial infarction

Cardiovascular Research

Volumn 91, Issue 1, 2011, Pages 99-107

  Carlson, Signe ^a   Trial, Joann ^a   Soeller, Christian ^b   Entman, Mark L ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Fibroblast precursors; Infarct repair; Mesenchymal stem cells; Precursor cell differentiation

Indexed keywords

COLLAGEN; TRANSCRIPTION FACTOR NANOG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; FIBROBLAST; HEART INFARCTION; MALE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; SCAR FORMATION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD44; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELLS, CULTURED; CICATRIX; DISEASE MODELS, ANIMAL; FIBRILLAR COLLAGENS; FIBROBLASTS; HOMEODOMAIN PROTEINS; MALE; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; MULTIPOTENT STEM CELLS; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOFIBROBLASTS; PHENOTYPE; TIME FACTORS; WOUND HEALING;

EID: 79958851882     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvr061     Document Type: Article

References (35)

1. Jugdutt BI. Remodeling of the myocardium and potential targets in the collagen degradation and synthesis pathways. Curr Drug Targets Cardiovasc Haematol Disord 2003;3: 1-30. (Pubitemid 36244902)
2. St John Sutton M, Pfeffer MA, Moye L, Plappert T, Rouleau JL, Lamas G et al. Cardiovascular death and left ventricular remodeling two years after myocardial infarction: baseline predictors and impact of long-term use of captopril: information from the Survival and Ventricular Enlargement (SAVE) trial. Circulation 1997;96:3294-3299. (Pubitemid 27513397)
3. Cohn JN, Ferrari R, Sharpe N. Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling. J Am Coll Cardiol 2000;35: 569-582. (Pubitemid 30167013)
4. Dewald O, Ren G, Duerr GD, Zoerlein M, Klemm C, Gersch C et al. Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction. Am J Pathol 2004;164:665-677. (Pubitemid 38364680)
5. Dobaczewski M, Gonzalez-Quesada C, Frangogiannis NG. The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction. J Mol Cell Cardiol 2010;48:504-511.
6. Dubois C, Liu X, Claus P, Marsboom G, Pokreisz P, Vandenwijngaert S et al. Differential effects of progenitor cell populations on left ventricular remodeling and myocardial neovascularization after myocardial infarction. J Am Coll Cardiol 2010;55:2232-2243.
7. Huang J, Zhang Z, Guo J, Ni A, Deb A, Zhang L et al. Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium. Circ Res 2010;106: 1753-1762.
8. Arminan A, Gandia C, Garcia-Verdugo JM, Lledo E, Trigueros C, Ruiz-Sauri A et al. Mesenchymal stem cells provide better results than hematopoietic precursors for the treatment of myocardial infarction. J Am Coll Cardiol 2010;55:2244-2253.
9. Nossuli TO, Lakshminarayanan V, Baumgarten G, Taffet GE, Ballantyne CM, Michael LH et al. A chronic mouse model of myocardial ischemia-reperfusion: essential in cytokine studies. Am J Physiol Heart Circ Physiol 2000;278:H1049-H1055. (Pubitemid 30235479)
10. Beckstead JH. A simple technique for preservation of fixation-sensitive antigens in paraffin-embedded tissues. J Histochem Cytochem 1994;42:1127-1134. (Pubitemid 24226340)
11. Haudek SB, Xia Y, Huebener P, Lee JM, Carlson S, Crawford JR et al. Bone marrowderived fibroblast precursors mediate ischemic cardiomyopathy in mice. Proc Natl Acad Sci USA 2006;103:18284-18289. (Pubitemid 44871650)
12. Romijn HJ, van Uum JF, Breedijk I, Emmering J, Radu I, Pool CW. Double immunolabeling of neuropeptides in the human hypothalamus as analyzed by confocal laser scanning fluorescence microscopy. J Histochem Cytochem 1999;47:229-236.
13. Soeller C, Cannell MB. Construction of a two-photon microscope and optimisation of illumination pulse duration. Pflugers Arch 1996;432:555-561. (Pubitemid 26246487)
14. Strupler M, Pena AM, Hernest M, Tharaux PL, Martin JL, Beaurepaire E et al. Second harmonic imaging and scoring of collagen in fibrotic tissues. Opt Express 2007;15: 4054-4065. (Pubitemid 46562398)
15. Plotnikov SV, Millard AC, Campagnola PJ, Mohler WA. Characterization of the myosin-based source for second-harmonic generation from muscle sarcomeres. Biophys J 2006;90:693-703.
16. Kretlow JD, Jin YQ, Liu W, Zhang WJ, Hong TH, Zhou G et al. Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cells. BMC Cell Biol 2008;9:60-72.
17. LinW, Shuster S, Maibach HI, Stern R. Patterns of hyaluronan staining are modified by fixation techniques. J Histochem Cytochem 1997;45:1157-1163. (Pubitemid 27347345)
18. Humason GL. Animal Tissue Techniques. San Francisco: W.H. Freeman & Company; 1967.
19. Dewald O, Zymek P, Winkelmann K, Koerting A, Ren G, Abou-Khamis T et al. CCL2/ monocyte chemoattractant protein-1 regulates inflammatory responses critical to healing myocardial infarcts. Circ Res 2005;96:881-889. (Pubitemid 40604972)
20. Bullock TE, Wen B, Marley SB, Gordon MY. Potential of CD34 in the regulation of symmetrical and asymmetrical divisions by hematopoietic progenitor cells. Stem Cells 2007;25:844-851. (Pubitemid 46572580)
21. Hatano SY, Tada M, Kimura H, Yamaguchi S, Kono T, Nakano T et al. Pluripotential competence of cells associated with Nanog activity. Mech Dev 2005;122:67-79. (Pubitemid 39593746)
22. Kashyap V, Rezende NC, Scotland KB, Shaffer SM, Persson JL, Gudas LJ et al. Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem Cells Dev 2009;18: 1093-1108.
23. Frangogiannis NG, Smith CW, Entman ML. The inflammatory response in myocardial infarction. Cardiovasc Res 2002;53:31-47. (Pubitemid 34020764)
24. Frangogiannis NG, Ren G, Dewald O, Zymek P, Haudek S, Koerting A et al. Critical role of endogenous throjmbospondin-1 in preventing expansion of healing myocardial infarcts. Circulation 2005;111:2935-2942. (Pubitemid 40814186)
25. Chamberlain G, Fox J, Ashton B, Middleton J. Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells 2007;25:2739-2749. (Pubitemid 350127858)
26. Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006;8: 315-317. (Pubitemid 44269669)
27. Shabbir A, Zisa D, Lin H, Mastri M, Roloff G, Suzuki G et al. Activation of host tissue trophic factors through JAK-STAT3 signaling: a mechanism of mesenchymal stem cell-mediated cardiac repair. Am J Physiol Heart Circ Physiol 2010;299: H1428-H1438.
28. Wang Y, Abarbanell AM, Herrmann JL, Weil BR, Manukyan MC, Poynter JA et al. TLR4 inhibits mesenchymal stem cell (MSC) STAT3 activation and thereby exerts deleterious effects on MSC-mediated cardioprotection. PLoS One 2010;5: e14206.
29. Maddox JR, Liao X, Li F, Niyibizi C. Effects of culturing on the stability of the putative murine adipose derived stem cells markers. Open Stem Cell J 2009;1:54-61.
30. Huebener P, Abou-Khamis T, Zymek P, Bujak M, Ying X, Chatila K et al. CD44 is critically involved in infarct healing by regulating the inflammatory and fibrotic response. J Immunol 2008;180:2625-2633.
31. Goldsmith EC, Hoffman A, Morales MO, Potts JD, Price RL, McFadden A et al. Organization of fibroblasts in the heart. Dev Dyn 2004;230:787-794. (Pubitemid 38993878)
32. Riekstina U, Cakstina I, Parfejevs V, Hoogduijn M, Jankovskis G, Muiznieks I et al. Embryonic stem cell marker expression pattern in human mesenchymal stem cells derived from bone marrow, adipose tissue, heart and dermis. Stem Cell Rev 2009;5: 378-386.
33. Young HE, Black AC Jr. Adult stem cells. Anat Rec A Discov Mol Cell Evol Biol 2004;276: 75-102. (Pubitemid 38067242)
34. Covas DT, Panepucci RA, Fontes AM, Silva WA Jr, Orellana MD, Freitas MC et al. Multipotent mesenchymal stromal cells obtained from diverse human tissues share functional properties and gene-expression profile with CD146+ perivascular cells and fibroblasts. Exp Hematol 2008;36:642-654.
35. Sarugaser R, Hanoun L, Keating A, Stanford WL, Davies JE. Human mesenchymal stem cells self-renew and differentiate according to a deterministic hierarchy. PLoS One 2009;4:e6498