Helicobacter pylori activates the TLR2/NLRP3/caspase-1/IL-18 axis to induce regulatory T-cells, establish persistent infection and promote tolerance to allergens

Gut Microbes

Volumn 6, Issue 6, 2015, Pages 382-387

  Koch, Katrin N ^a   Müller, Anne ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Allergic diseases; Gastrointestinal microbiota; Microbial immunomodulation; Nod like receptors; Proinflammatory cytokines; Regulatory Tcells; Toll like receptors; Transposon mutagenesis

Indexed keywords

ALLERGEN; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; TOLL LIKE RECEPTOR 2; UREASE; BACTERIAL ANTIGEN; CARRIER PROTEIN; NLRP3 PROTEIN, HUMAN; TLR2 PROTEIN, HUMAN;

ARTICLE; ASTHMA; CD4+ CD25+ T LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; IMMUNITY; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; INFLAMMATORY BOWEL DISEASE; MULTIPLE SCLEROSIS; NONHUMAN; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; IMMUNOLOGY; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, BACTERIAL; CARRIER PROTEINS; CASPASE 1; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNE TOLERANCE; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TOLL-LIKE RECEPTOR 2;

EID: 84964282449     PISSN: 19490976     EISSN: 19490984     Source Type: Journal    
DOI: 10.1080/19490976.2015.1105427     Document Type: Article

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