Helicobacter urease-induced activation of the TLR2/NLRP3/IL-18 axis protects against asthma

Journal of Clinical Investigation

Volumn 125, Issue 8, 2015, Pages 3297-3302

  Koch, Katrin N ^a   Hartung, Mara L ^a   Urban, Sabine ^a   Kyburz, Andreas ^a   Bahlmann, Anna S ^a   Lind, Judith ^b   Backert, Steffen ^b   Taube, Christian ^c   Müller, Anne ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BACTERIAL ENZYME; CD4 ANTIGEN; CRYOPYRIN; HELICOBACTER UREASE; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG; UREASE; BACTERIAL PROTEIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; IL1B PROTEIN, MOUSE; INTERLEUKIN-18 BINDING PROTEIN; SIGNAL PEPTIDE; TLR2 PROTEIN, MOUSE;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD GROUP LEWIS SYSTEM; BONE MARROW; DISEASE CONTROL; ENZYME ACTIVATION; GENE CLUSTER; GENETIC CODE; HELICOBACTER PYLORI; IMMUNOREGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSPOSON; ANIMAL; ASTHMA; DENDRITIC CELL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE;

ANIMALS; ASTHMA; BACTERIAL PROTEINS; CARRIER PROTEINS; DENDRITIC CELLS; GENE EXPRESSION REGULATION; HELICOBACTER PYLORI; HUMANS; INFLAMMASOMES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-1BETA; MICE; MICE, KNOCKOUT; TOLL-LIKE RECEPTOR 2; UREASE;

EID: 84939250460     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI79337     Document Type: Article

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