1,25-Dihydroxyvitamin D3 causes ADAM10-dependent ectodomain shedding of tumor necrosis factor receptor 1 in vascular smooth muscle cells

Molecular Pharmacology

Volumn 87, Issue 3, 2015, Pages 533-542

  Yang, Won Seok ^a   Kim, Hyun Woo ^b   Lee, Joo Mi ^c   Han, Nam Jeong ^c   Lee, Mee Jeong ^d   Park, Su Kil ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Jeju National University School of Medicine   (South Korea)

^c Asan Institute for Life Sciences   (South Korea)

^d Dankook University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ADAM PROTEIN; ADAM10 ENDOPEPTIDASE; ADAM10 PROTEIN, HUMAN; CALCITRIOL; CALCIUM CHANNEL L TYPE; CALCIUM ION; DISINTEGRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE PROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PHARMACOLOGY; PROTEIN KINASE SYK; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; SECRETASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; VERAPAMIL;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM DEPLETION; CELL CULTURE; CELL MEMBRANE; CELL SURFACE; CLINICAL EVALUATION; CYTOPLASM; DRUG EFFECT; DRUG EFFECTS; ENZYME ACTIVATION; EXTRACELLULAR CALCIUM; GENE EXPRESSION; GENE TRANSLOCATION; GENETIC REGULATION; HUMAN; HUMAN CELL; METABOLISM; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; CALCITRIOL; CELLS, CULTURED; DRUG EFFECTS; HUMANS; MEMBRANE PROTEINS; METABOLISM; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHARMACOLOGY; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I;

EID: 84964265984     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.114.097147     Document Type: Article

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