TNF-induced shedding of TNF receptors in human polymorphonuclear leukocytes: Role of the 55-kDa TNF receptor and involvement of a membrane- bound and non-matrix metalloproteinase

Journal of Immunology

Volumn 165, Issue 4, 2000, Pages 2165-2172

  Dri, P ^a   Gasparini, C ^a   Menegazzi, R ^a   Cramer, R ^a   Alberi, L ^a   Presani, G ^a   Garbisa, S ^a   Patriarca, P ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1,10 PHENANTHROLINE; DYFLOS; HYDROXAMIC ACID; MATRIX METALLOPROTEINASE; PROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ARTICLE; CELL ACTIVITY; CELL FUNCTION; CELL STIMULATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKOCYTE; NEUTROPHIL; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SECRETION; REGULATORY MECHANISM;

EID: 0034663825     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.4.2165     Document Type: Article

References (63)

1. Tissue destruction by neutrophils
2. Tumor necrosis factor α (TNF-α)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55
3. Activation of human polymorphonuclear neutrophil functions by interferon-γ and tumor necrosis factor
4. Recombinant tumor necrosis factor-α: Regulation of N- formylmethionylleucylphenylalanine receptor affinity and function on human neutrophils
5. Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor
6. Human polymorphonuclear leucocytes stimulated by tumor necrosis factor-α show increased adherence to extracellular matrix proteins which is mediated via the CD11b/CD18 complex
7. Neutrophil activation on biological surfaces: Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes
8. Cytokine-induced respiratory burst of human neutrophils: Dependence on extracellular matrix proteins and CD11/CD18 integrins
9. Effect of tumor necrosis factor and granulocyte/macrophage colony- stimulating factor on neutrophil degranulation
10. Two TNF receptors
11. Shedding of tumor necrosis factor receptors by activated human neutrophils
12. The tumor necrosis factor receptor and human neutrophil function: Deactivation and cross-deactivation of tumor necrosis factor-induced neutrophil responses by receptor down-regulation
13. Adherence of neutrophils induces release of soluble tumor necrosis factor receptor forms
14. Tumor necrosis factor induces a selective shedding of its p75 receptor from human neutrophils
15. TNF-specific deactivation of granulocytes in vivo: A possible mechanism of self-protection
16. Factor-specific changes in oxidative burst response of human neutrophils in skin-window exudates
17. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor α in vitro and in vivo
18. Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors
19. Increased circulating cytokine receptors and ex vivo interleukin-1 receptor antagonist and interleukin-1β production but decreased tumor necrosis factor-α production after a 5-km run
20. Endotoxin induces down-regulation of tumor necrosis factor receptors on circulating monocytes and granulocytes in humans
21. Kinetics of circulating TNF-α and TNF soluble receptors following surgery in a clinical model of sepsis
22. Systemic release of soluble TNF receptors after high-dose TNF in isolated limb perfusion
23. Metalloproteinase-mediated release of human Fas ligand
24. A metalloprotease inhibitor prevents lethal acute graft-versus-host disease in mice
25. Synthesis and refolding of human TIMP-2 from E. coli, with specific activity for MMP-2
26. Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses
27. Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies
28. A metalloproteinase disintegrin that releases tumor-necrosis factor-α from cells
29. A novel, secreted form of human ADAM 12 (meltrin α) provokes myogenesis in vivo
30. Cysteine-rich domain of human ADAM 12 (meltrin α) supports tumor cell adhesion
31. Human tumor necrosis factor α (TNF α) mutants with exclusive specificity for the 55-kDa or 75-kDa TNF receptors
32. Preparation of cells and materials for functional assays
33. Role of the 75-kDa TNF receptor in TNF-induced activation of neutrophil respiratory burst
34. TNF induces internalization of the p60 receptor and shedding of the p80 receptor
35. Metalloprotease are involved in cleavage of CD43, CD44, and CD16 from stimulated human granulocytes
36. Metalloproteases and serinproteases are involved in the cleavage of two tumor necrosis factor (TNF) receptors to soluble forms in the myeloid cell lines U-937 and THP-1
37. Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors
38. Purification of human collagenases with a hydroxamic acid affinity column
39. Collagenase is a component of the specific granules of human neutrophil leukocytes
40. Subcellular localization and release of human neutrophil gelatinase, confirming the existence of separate gelatinase-containing granules
41. Inhibitors of metalloproteases
42. Matrix metalloproteinases and their inhibitors
43. An essential role for ectodomain shedding in mammalian development
44. A cellular striptease act
45. Human ADAM 12 (meltrin α) is an active metalloprotease
46. The pathophysiology of tumor necrosis factors
47. Shock and tissue injury induced by recombinant human cachectin
48. Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock
49. Activation of coagulation after administration of tumor necrosis factor to normal subjects
50. Functions of the tumor necrosis factor receptors TNF-R55 and TNF-R75 in TNF-induced activation of human neutrophils
51. A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor
52. A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes
53. Paradoxical effects of a synthetic metalloprotease inhibitor that blocks both p55 and p75 TNF receptor shedding and TNFα processing in RA synovial membrane cell cultures
54. Introduction: Clan MA containing thermolysin and its relatives
55. ADAM metalloproteinases
56. CD156 (human ADAM8): Expression, primary amino acid sequence, and gene location
57. MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains
58. Metalloprotease-disintegrin MDC9: Intracellular maturation and catalytic activity
59. Identification and characterization of a pro-tumor necrosis factor-α- processing enzyme from the ADAM family of zinc metalloproteases
60. Cloning of a disintegrin metalloprotease that processes precursor tumour-necrosis factor-α
61. Crystal structure of the catalytic domain of human tumor necrosis factor-α-converting enzyme
62. Stability constants of metal complexes
63. Evidence that tumor necrosis factor α (TNF)-induced activation of neutrophil respiratory burst on biologic surfaces is mediated by the p55 TNF receptor