Oat Avenanthramide-C (2c) is biotransformed by mice and the human microbiota into bioactive metabolites

Journal of Nutrition

Volumn 145, Issue 2, 2015, Pages 239-245

  Wang, Pei ^a   Chen, Huadong ^a   Zhu, Yingdong ^a   McBride, Jennifer ^a   Fu, Junsheng ^a   Sang, Shengmin ^a  

^a NORTH CAROLINA A AND T STATE UNIVERSITY   (United States)

Author keywords

2c; Apoptosis; Avenanthramide C; Colon cancer cells; Human microbiota; Interindividual variation; Metabolism; Mice; Oat

Indexed keywords

3,4-DIHYDROXYPHENYLPROPIONIC ACID; 5 HYDROXYANTHRANILIC ACID; ALKALOID; ANTHRANILIC ACID DERIVATIVE; AVENANTHRAMIDE B; AVENANTHRAMIDE C; AVENANTHRAMIDE-2C; CAFFEIC ACID; CAFFEIC ACID DERIVATIVE; COUMARIC ACID; DIHYDROAVENANTHRAMIDE B; DIHYDROAVENANTHRAMIDE C; DIHYDROCAFFEIC ACID; DIHYDROFERULIC ACID; DRUG ADMINISTRATION; FERULIC ACID; PHARMACOKINETICS; UNCLASSIFIED DRUG;

ADULT; ANIMAL; APOPTOSIS; ARTICLE; BACTERIUM CULTURE; BIOLOGICAL ACTIVITY; BIOTRANSFORMATION; BODY MASS; CHEMISTRY; CONTROLLED STUDY; DRUG CLEARANCE; DRUG EFFECTS; DRUG HALF LIFE; DRUG METABOLISM; ELECTROCHEMICAL DETECTION; ELECTROSPRAY MASS SPECTROMETRY; FECES; FEMALE; HCT116 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MALE; MICROBIOLOGY; MICROFLORA; MOUSE; NONHUMAN; NORMAL HUMAN; OAT; URINE;

ADMINISTRATION AND DOSAGE; ADULT; ANIMALS; APOPTOSIS; AVENA SATIVA; BIOTRANSFORMATION; BODY MASS INDEX; CAFFEIC ACIDS; CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARIC ACIDS; DRUG EFFECTS; FECES; FEMALE; HCT116 CELLS; HEALTHY VOLUNTEERS; HUMANS; MALE; MICE; MICROBIOLOGY; MICROBIOTA; ORTHO-AMINOBENZOATES; PHARMACOKINETICS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; URINE;

AVENA; MUS;

EID: 84964265168     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.114.206508     Document Type: Article

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