PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells

Journal of Cell Science

Volumn 129, Issue 7, 2016, Pages 1340-1354

  Rogers, Samuel ^a   Fey, Dirk ^b   McCloy, Rachael A ^a   Parker, Benjamin L ^c   Mitchell, Nicholas J ^d   Payne, Richard J ^d   Daly, Roger J ^e   James, David E ^c   Caldon, C Elizabeth ^a,f   Watkins, D Neil ^a,f,g   Croucher, David R ^a,f   Burgess, Andrew ^a,f  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSITY OF SYDNEY   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

^e MONASH UNIVERSITY   (Australia)

^f ST VINCENT'S CLINIC   (Australia)

^g ST VINCENT S HOSPITAL   (Australia)

Author keywords

Bistable switch; Cdk1; Greatwall; Kinase; MASTL; Mitotic exit; Phosphatase; PP1; PP2A

Indexed keywords

CYCLIN DEPENDENT KINASE 1; MICROTUBULE ASSOCIATED SERINE THREONINE LIKE KINASE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; CDK1 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; MASTL PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA;

ARTICLE; CONTROLLED STUDY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METAPHASE; MITOSIS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; ANTAGONISTS AND INHIBITORS; GENETICS; HELA CELL LINE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RNA INTERFERENCE; THEORETICAL MODEL; TUMOR CELL LINE;

CDC2 PROTEIN KINASE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASES; HELA CELLS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; MODELS, THEORETICAL; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 2; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84964076485     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.179754     Document Type: Article

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