메뉴 건너뛰기




Volumn 15, Issue 5, 2013, Pages 519-525

The Cdk1-APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CELL CYCLE PROTEIN 20; CYCLIN DEPENDENT KINASE 1;

EID: 84877578533     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2737     Document Type: Article
Times cited : (119)

References (39)
  • 2
    • 0000915688 scopus 로고
    • On the relation between the logical structure of systems and their ability to generate multiple steady states or sustained oscillations
    • Thomas, R. On the relation between the logical structure of systems and their ability to generate multiple steady states or sustained oscillations. Springer Ser. Synergetics 9, 180-193 (1981).
    • (1981) Springer Ser. Synergetics , vol.9 , pp. 180-193
    • Thomas, R.1
  • 3
    • 0034212551 scopus 로고    scopus 로고
    • Engineering stability in gene networks by autoregulation
    • DOI 10.1038/35014651
    • Becskei, A. & Serrano, L. Engineering stability in gene networks by autoregulation. Nature 405, 590-593 (2000). (Pubitemid 30367734)
    • (2000) Nature , vol.405 , Issue.6786 , pp. 590-593
    • Becskel, A.1    Serrano, L.2
  • 4
    • 0014319313 scopus 로고
    • Mathematics of cellular control processes I. Negative feedback to one gene
    • Grif-th, J. S. Mathematics of cellular control processes. I. Negative feedback to one gene. J. Theor. Biol. 20, 202-208 (1968).
    • (1968) J. Theor. Biol , vol.20 , pp. 202-208
    • Grif-Th, J.S.1
  • 5
    • 0002275384 scopus 로고
    • The dynamics of feedback control circuits in biochemical pathways
    • Tyson, J. J. & Othmer, H. G. The dynamics of feedback control circuits in biochemical pathways. Prog. Theor. Biol. 5, 1-62 (1978).
    • (1978) Prog. Theor. Biol , vol.5 , pp. 1-62
    • Tyson, J.J.1    Othmer, H.G.2
  • 6
    • 56749160113 scopus 로고    scopus 로고
    • Design principles of biochemical oscillators
    • Novak, B. & Tyson, J. J. Design principles of biochemical oscillators. Nat. Rev. Mol. Cell Biol. 9, 981-991 (2008).
    • (2008) Nat. Rev. Mol. Cell Biol , vol.9 , pp. 981-991
    • Novak, B.1    Tyson, J.J.2
  • 7
    • 57049159362 scopus 로고    scopus 로고
    • A fast, robust and tunable synthetic gene oscillator
    • DOI 10.1038/nature07389, PII NATURE07389
    • Stricker, J., Cookson, S., Bennett, M., Tsimring, L. & Hasty, J. A fast, robust, and tunable synthetic gene oscillator. Nature 456, 516-519 (2008). (Pubitemid 352759003)
    • (2008) Nature , vol.456 , Issue.7221 , pp. 516-519
    • Stricker, J.1    Cookson, S.2    Bennett, M.R.3    Mather, W.H.4    Tsimring, L.S.5    Hasty, J.6
  • 8
    • 46849090495 scopus 로고    scopus 로고
    • Robust, tunable biological oscillations from interlinked positive and negative feedback loops
    • Tsai, T. Y. et al. Robust, tunable biological oscillations from interlinked positive and negative feedback loops. Science 321, 126-129 (2008).
    • (2008) Science , vol.321 , pp. 126-129
    • Tsai, T.Y.1
  • 9
    • 0018845758 scopus 로고
    • A cytoplasmic clock with the same period as the division cycle in Xenopus eggs
    • Hara, K., Tydeman, P. & Kirschner, M. A cytoplasmic clock with the same period as the division cycle in Xenopus eggs. Proc. Natl Acad. Sci. USA 77, 462-466 (1980).
    • (1980) Proc. Natl Acad. Sci. USA , vol.77 , pp. 462-466
    • Hara, K.1    Tydeman, P.2    Kirschner, M.3
  • 10
    • 0024425274 scopus 로고
    • Dominoes and clocks: The union of two views of the cell cycle
    • Murray, A. W. & Kirschner, M. W. Dominoes and clocks: the union of two views of the cell cycle. Science 246, 614-621 (1989). (Pubitemid 19283352)
    • (1989) Science , vol.246 , Issue.4930 , pp. 614-621
    • Murray, A.W.1    Kirschner, M.W.2
  • 11
    • 79959555511 scopus 로고    scopus 로고
    • Cubism and the cell cycle: The many faces of the APC/C
    • Pines, J. Cubism and the cell cycle: the many faces of the APC/C. Nat. Rev. Mol. Cell Biol. 12, 427-438 (2011).
    • (2011) Nat. Rev. Mol. Cell Biol , vol.12 , pp. 427-438
    • Pines, J.1
  • 12
    • 0029004815 scopus 로고
    • A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-speci-c conjugation of ubiquitin to cyclin B
    • King, R. W. et al. A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-speci-c conjugation of ubiquitin to cyclin B. Cell 81, 279-288 (1995).
    • (1995) Cell , vol.81 , pp. 279-288
    • King, R.W.1
  • 14
    • 0345700833 scopus 로고    scopus 로고
    • Building a cell cycle oscillator: Hysteresis and bistability in the activation of Cdc2
    • DOI 10.1038/ncb954
    • Pomerening, J. R., Sontag, E. D. & Ferrell, J. E. Jr Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2. Nat. Cell Biol. 5, 346-351 (2003). (Pubitemid 36432300)
    • (2003) Nature Cell Biology , vol.5 , Issue.4 , pp. 346-351
    • Pomerening, J.R.1    Sontag, E.D.2    Ferrell Jr., J.E.3
  • 15
    • 23944469094 scopus 로고    scopus 로고
    • Systems-level dissection of the cell-cycle oscillator: Bypassing positive feedback produces damped oscillations
    • DOI 10.1016/j.cell.2005.06.016, PII S0092867405005994
    • Pomerening, J. R., Kim, S. Y. & Ferrell, J. E. Jr Systems-level dissection of the cell-cycle oscillator: bypassing positive feedback produces damped oscillations. Cell 122, 565-578 (2005). (Pubitemid 41191155)
    • (2005) Cell , vol.122 , Issue.4 , pp. 565-578
    • Pomerening, J.R.1    Sun, Y.K.2    Ferrell Jr., J.E.3
  • 16
    • 0025367233 scopus 로고
    • Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase
    • Felix, M. A., Labbe, J. C., Doree, M., Hunt, T. & Karsenti, E. Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase. Nature 346, 379-382 (1990).
    • (1990) Nature , vol.346 , pp. 379-382
    • Felix, M.A.1    Labbe, J.C.2    Doree, M.3    Hunt, T.4    Karsenti, E.5
  • 17
    • 33947304756 scopus 로고    scopus 로고
    • Substrate Competition as a Source of Ultrasensitivity in the Inactivation of Wee1
    • DOI 10.1016/j.cell.2007.01.039, PII S0092867407002024
    • Kim, S. Y. & Ferrell, J. E. Jr Substrate competition as a source of ultrasensitivity in the inactivation of Wee1. Cell 128, 1133-1145 (2007). (Pubitemid 46437260)
    • (2007) Cell , vol.128 , Issue.6 , pp. 1133-1145
    • Kim, S.Y.1    Ferrell Jr., J.E.2
  • 18
    • 79251534050 scopus 로고    scopus 로고
    • Ultrasensitivity in the regulation of Cdc25C by Cdk1
    • Trunnell, N. B., Poon, A. C., Kim, S. Y. & Ferrell, J. E. Jr Ultrasensitivity in the regulation of Cdc25C by Cdk1. Mol. Cell 41, 263-274 (2011).
    • (2011) Mol. Cell , vol.41 , pp. 263-274
    • Trunnell, N.B.1    Poon, A.C.2    Kim, S.Y.3    Ferrell, J.E.4
  • 19
    • 70349210060 scopus 로고    scopus 로고
    • Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts
    • Mochida, S., Ikeo, S., Gannon, J. & Hunt, T. Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts. EMBO J. 28, 2777-2785 (2009).
    • (2009) EMBO J , vol.28 , pp. 2777-2785
    • Mochida, S.1    Ikeo, S.2    Gannon, J.3    Hunt, T.4
  • 20
    • 79952282492 scopus 로고    scopus 로고
    • How APC/C-Cdc20 changes its substrate speci-city in mitosis
    • Izawa, D. & Pines, J. How APC/C-Cdc20 changes its substrate speci-city in mitosis. Nat. Cell Biol. 13, 223-233 (2011).
    • (2011) Nat. Cell Biol , vol.13 , pp. 223-233
    • Izawa, D.1    Pines, J.2
  • 21
    • 0028134981 scopus 로고
    • A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts
    • DOI 10.1016/0092-8674(94)90256-9
    • Minshull, J., Sun, H., Tonks, N. K. & Murray, A. W. A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts. Cell 79, 475-486 (1994). (Pubitemid 24346062)
    • (1994) Cell , vol.79 , Issue.3 , pp. 475-486
    • Minshull, J.1    Sun, H.2    Tonks, N.K.3    Murray, A.W.4
  • 22
    • 0025041797 scopus 로고
    • The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle
    • Minshull, J., Golsteyn, R., Hill, C. S. & Hunt, T. The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle. EMBO J. 9, 2865-2875 (1990).
    • (1990) EMBO J , vol.9 , pp. 2865-2875
    • Minshull, J.1    Golsteyn, R.2    Hill, C.S.3    Hunt, T.4
  • 23
    • 81855184983 scopus 로고    scopus 로고
    • Ubiquitination of Cdc20 by the APC occurs through an intramolecular mechanism
    • Foe, I. T. et al. Ubiquitination of Cdc20 by the APC occurs through an intramolecular mechanism. Curr. Biol. 21, 1870-1877 (2011).
    • (2011) Curr. Biol , vol.21 , pp. 1870-1877
    • Foe, I.T.1
  • 25
    • 0024978338 scopus 로고
    • Cyclin synthesis drives the early embryonic cell cycle
    • Murray, A. W. & Kirschner, M. W. Cyclin synthesis drives the early embryonic cell cycle. Nature 339, 275-280 (1989).
    • (1989) Nature , vol.339 , pp. 275-280
    • Murray, A.W.1    Kirschner, M.W.2
  • 26
    • 0030249292 scopus 로고    scopus 로고
    • A quantitative model for the cdc2 control of S phase and mitosis in fission yeast
    • DOI 10.1016/0168-9525(96)10036-6
    • Stern, B. & Nurse, P. A quantitative model for the cdc2 control of S phase and mitosis in -ssion yeast. Trends Gene. 12, 345-350 (1996). (Pubitemid 26294693)
    • (1996) Trends in Genetics , vol.12 , Issue.9 , pp. 345-350
    • Stern, B.1    Nurse, P.2
  • 27
    • 78650842310 scopus 로고    scopus 로고
    • Driving the cell cycle with a minimal CDK control network
    • Coudreuse, D. & Nurse, P. Driving the cell cycle with a minimal CDK control network. Nature 468, 1074-1079 (2010).
    • (2010) Nature , vol.468 , pp. 1074-1079
    • Coudreuse, D.1    Nurse, P.2
  • 28
    • 79958723796 scopus 로고    scopus 로고
    • Rising cyclin-CDK levels order cell cycle events
    • Oikonomou, C. & Cross, F. R. Rising cyclin-CDK levels order cell cycle events. PLoS One 6, e20788 (2011).
    • (2011) PLoS One , vol.6
    • Oikonomou, C.1    Cross, F.R.2
  • 29
    • 77951184302 scopus 로고    scopus 로고
    • Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis
    • Gavet, O. & Pines, J. Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis. Dev. Cell 18, 533-543 (2010).
    • (2010) Dev. Cell , vol.18 , pp. 533-543
    • Gavet, O.1    Pines, J.2
  • 30
    • 0037154005 scopus 로고    scopus 로고
    • Timing of events in mitosis
    • DOI 10.1016/S0960-9822(01)00662-5, PII S0960982201006625
    • Georgi, A. B., Stukenberg, P. T. & Kirschner, M. W. Timing of events in mitosis. Curr. Biol. 12, 105-114 (2002). (Pubitemid 34099133)
    • (2002) Current Biology , vol.12 , Issue.2 , pp. 105-114
    • Georgi, A.B.1    Stukenberg P.Todd2    Kirschner, M.W.3
  • 31
    • 27944500696 scopus 로고    scopus 로고
    • Multisite M-phase phosphorylation of Xenopus Wee1A
    • DOI 10.1128/MCB.25.23.10580-10590.2005
    • Kim, S. Y., Song, E. J., Lee, K. J. & Ferrell, J. E. Jr Multisite M-phase phosphorylation of Xenopus Wee1A. Mol. Cell Biol. 25, 10580-10590 (2005). (Pubitemid 41681978)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.23 , pp. 10580-10590
    • Kim, S.Y.1    Song, E.J.2    Lee, K.-J.3    Ferrell Jr., J.E.4
  • 32
    • 47549106474 scopus 로고    scopus 로고
    • Positive feedback of G1 cyclins ensures coherent cell cycle entry
    • DOI 10.1038/nature07118, PII NATURE07118
    • Skotheim, J. M., Di Talia, S., Siggia, E. D. & Cross, F. R. Positive feedback of G1 cyclins ensures coherent cell cycle entry. Nature 454, 291-296 (2008). (Pubitemid 352009994)
    • (2008) Nature , vol.454 , Issue.7202 , pp. 291-296
    • Skotheim, J.M.1    Di Talia, S.2    Siggia, E.D.3    Cross, F.R.4
  • 33
    • 80051720034 scopus 로고    scopus 로고
    • Distinct interactions select and maintain a speci-c cell fate
    • Doncic, A., Falleur-Fettig, M. & Skotheim, J. M. Distinct interactions select and maintain a speci-c cell fate. Mol. Cell 43, 528-539 (2011).
    • (2011) Mol. Cell , vol.43 , pp. 528-539
    • Doncic, A.1    Falleur-Fettig, M.2    Skotheim, J.M.3
  • 34
    • 55949119059 scopus 로고    scopus 로고
    • A role for the Fizzy/Cdc20 family of proteins in activation of the APC/C distinct from substrate recruitment
    • Kimata, Y., Baxter, J. E., Fry, A. M. & Yamano, H. A role for the Fizzy/Cdc20 family of proteins in activation of the APC/C distinct from substrate recruitment. Mol. Cell 32, 576-583 (2008).
    • (2008) Mol. Cell , vol.32 , pp. 576-583
    • Kimata, Y.1    Baxter, J.E.2    Fry, A.M.3    Yamano, H.4
  • 37
    • 0026263951 scopus 로고
    • Systems for the study of nuclear assembly DNA replication, and nuclear breakdown in Xenopus laevis egg extracts
    • Smythe, C. & Newport, J. W. Systems for the study of nuclear assembly, DNA replication, and nuclear breakdown in Xenopus laevis egg extracts. Meth. Cell Biol. 35, 449-468 (1991).
    • (1991) Meth. Cell Biol , vol.35 , pp. 449-468
    • Smythe, C.1    Newport, J.W.2
  • 38
    • 0026266161 scopus 로고
    • Cell cycle extracts
    • Murray, A. W. Cell cycle extracts. Meth. Cell Biol. 36, 581-605 (1991).
    • (1991) Meth. Cell Biol , vol.36 , pp. 581-605
    • Murray, A.W.1
  • 39
    • 0037166938 scopus 로고    scopus 로고
    • Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1
    • DOI 10.1083/jcb.200111001
    • Hagting, A. et al. Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1. J. Cell Biol. 157, 1125-1137 (2002). (Pubitemid 34847784)
    • (2002) Journal of Cell Biology , vol.157 , Issue.7 , pp. 1125-1137
    • Hagting, A.1    Den Elzen, N.2    Vodermaier, H.C.3    Waizenegger, I.C.4    Peters, J.-M.5    Pines, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.