Low-volume formulation of intra-articular tranexamic acid, 25-ml tranexamic acid (2.5g) plus 20-ml saline, is effective in decreasing blood transfusion rate in primary total knee replacement even without preoperative haemoglobin optimization

Blood Coagulation and Fibrinolysis

Volumn 27, Issue 6, 2016, Pages 660-666

  Rodriguez Merchan, E Carlos ^a,b   Ortega Andreu, Miguel ^a   Padilla Eguiluz, Norma G ^a,b   Gomez Cardero, Primitivo ^a   Martinez Lloreda, Ángel ^a   Gomez Barrena, Enrique ^a,b  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

intra articular; total knee replacement; tranexamic acid; transfusion rate

Indexed keywords

HEMOGLOBIN; SODIUM CHLORIDE; TRANEXAMIC ACID; ANTIFIBRINOLYTIC AGENT;

ADULT; AGED; ARTICLE; BLOOD TRANSFUSION; COHORT ANALYSIS; DRUG EFFICACY; FEMALE; FOLLOW UP; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HUMAN; INTERNATIONAL NORMALIZED RATIO; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE CARE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TOTAL KNEE ARTHROPLASTY; VERY ELDERLY; BLOOD LOSS, SURGICAL; DOSE RESPONSE; DRUG ADMINISTRATION; DRUG EFFECTS; INTRAARTICULAR DRUG ADMINISTRATION; KNEE; KNEE REPLACEMENT; METABOLISM; MIDDLE AGED; ODDS RATIO; OSTEOARTHRITIS, KNEE; PATHOLOGY; PATHOPHYSIOLOGY; POSTOPERATIVE CARE; PROCEDURES; REGRESSION ANALYSIS; STATISTICS AND NUMERICAL DATA; TREATMENT OUTCOME; VASCULARIZATION;

AGED; AGED, 80 AND OVER; ANTIFIBRINOLYTIC AGENTS; ARTHROPLASTY, REPLACEMENT, KNEE; BLOOD LOSS, SURGICAL; BLOOD TRANSFUSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HEMOGLOBINS; HUMANS; INJECTIONS, INTRA-ARTICULAR; KNEE JOINT; MALE; MIDDLE AGED; ODDS RATIO; OSTEOARTHRITIS, KNEE; POSTOPERATIVE CARE; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; SODIUM CHLORIDE; TRANEXAMIC ACID; TREATMENT OUTCOME;

EID: 84964049161     PISSN: 09575235     EISSN: 14735733     Source Type: Journal    
DOI: 10.1097/MBC.0000000000000457     Document Type: Article

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