Myocardial Galectin-3 Expression Is Associated with Remodeling of the Pressure-Overloaded Heart and May Delay the Hypertrophic Response without Affecting Survival, Dysfunction, and Cardiac Fibrosis

American Journal of Pathology

Volumn 186, Issue 5, 2016, Pages 1114-1127

  Frunza, Olga ^a   Russo, Ilaria ^a   Saxena, Amit ^a   Shinde, Arti V ^a   Humeres, Claudio ^a   Hanif, Waqas ^a   Rai, Vikrant ^a   Su, Ya ^a   Frangogiannis, Nikolaos G ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GALECTIN 3; BIOLOGICAL MARKER; INTERLEUKIN 1BETA; SMAD3 PROTEIN; SMAD3 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; ARTICLE; CARDIAC MUSCLE; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; DISEASE ASSOCIATION; HEART FIBROBLAST; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE OVERLOAD; IMAGING SYSTEM; MACROPHAGE; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SURVIVAL; SYSTOLIC DYSFUNCTION; UPREGULATION; VASCULAR REMODELING; ANIMAL; BLOOD PRESSURE; C57BL MOUSE; CARDIOMEGALY; DIAGNOSTIC IMAGING; DOPPLER ECHOCARDIOGRAPHY; FEMALE; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE REMODELING; KNOCKOUT MOUSE; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; BIOMARKERS; BLOOD PRESSURE; CARDIOMEGALY; ECHOCARDIOGRAPHY, DOPPLER; ENDOMYOCARDIAL FIBROSIS; FEMALE; GALECTIN 3; INTERLEUKIN-1BETA; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIUM; MYOFIBROBLASTS; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84963995326     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.12.017     Document Type: Article

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