An endothelial TLR4-VEGFR2 pathway mediates lung protection against oxidant-induced injury

FASEB Journal

Volumn 30, Issue 3, 2016, Pages 1317-1327

  Takyar, Seyedtaghi ^a   Zhang, Yi ^a   Haslip, Maria ^a   Jin, Lei ^a   Shan, Peiying ^a   Zhang, Xuchen ^a,b   Lee, Patty J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

HALI; Lung injury; TLR4; VEGF

Indexed keywords

HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; RECOMBINANT VASCULOTROPIN; TOLL LIKE RECEPTOR 4; VASCULOTROPIN RECEPTOR 2; KDR PROTEIN, MOUSE; OXIDIZING AGENT; OXYGEN; TLR4 PROTEIN, MOUSE; VASCULOTROPIN A;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME RELEASE; GENE SILENCING; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HYPEROXIA; IN VIVO STUDY; LUNG; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; ENDOTHELIAL CELLS; HYDROGEN PEROXIDE; HYPEROXIA; LUNG; LUNG INJURY; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OXIDANTS; OXYGEN; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84963976431     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.15-275024     Document Type: Article

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