A comparison of methods to adjust for continuous covariates in the analysis of randomised trials

BMC Medical Research Methodology

Volumn 16, Issue 1, 2016, Pages

  Kahan, Brennan C ^a   Rushton, Helen ^b   Morris, Tim P ^c,d   Daniel, Rhian M ^d  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c MRC CLINICAL TRIALS UNIT   (United Kingdom)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Continuous variables; Covariate adjustment; Fractional polynomials; Randomised controlled trial; Restricted cubic splines

Indexed keywords

DIETHYLSTILBESTROL;

ALGORITHM; CANCER STAGING; COMPARATIVE STUDY; COMPUTER SIMULATION; DISEASE FREE SURVIVAL; HUMAN; MALE; MORTALITY; PATHOLOGY; PROPORTIONAL HAZARDS MODEL; PROSTATIC NEOPLASMS; RANDOMIZED CONTROLLED TRIAL (TOPIC); STATISTICAL MODEL; SURVIVAL ANALYSIS; TREATMENT OUTCOME; TUMOR INVASION;

ALGORITHMS; COMPUTER SIMULATION; DIETHYLSTILBESTROL; DISEASE-FREE SURVIVAL; HUMANS; LINEAR MODELS; MALE; MODELS, STATISTICAL; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROPORTIONAL HAZARDS MODELS; PROSTATIC NEOPLASMS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84963811790     PISSN: None     EISSN: 14712288     Source Type: Journal    
DOI: 10.1186/s12874-016-0141-3     Document Type: Article

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