The impact of covariate adjustment at randomization and analysis for binary outcomes: Understanding differences between superiority and noninferioritytrials

Statistics in Medicine

Volumn 34, Issue 11, 2015, Pages 1834-1840

  Nicholas, Katherine ^a   Yeatts, Sharon D ^a   Zhao, Wenle ^a   Ciolino, Jody ^b   Borg, Keith ^a   Durkalski, Valerie ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Clinical trials; Covariates; Noninferiority; Randomization

Indexed keywords

ALTERNATIVE HYPOTHESIS; ANALYSIS OF COVARIANCE; ANALYTICAL ERROR; ARTICLE; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; COVARIANCE; COVARIATE ADJUSTMENT; LOGISTIC REGRESSION ANALYSIS; NULL HYPOTHESIS; OUTCOME ASSESSMENT; POWER ANALYSIS; PROGNOSIS; RANDOMIZATION; STATISTICAL BIAS; STUDY DESIGN; ALGORITHM; COMPUTER SIMULATION; HUMAN; METHODOLOGY; RANDOMIZED CONTROLLED TRIAL (TOPIC); STATISTICAL MODEL;

ALGORITHMS; COMPUTER SIMULATION; HUMANS; LOGISTIC MODELS; PROGNOSIS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH DESIGN;

EID: 84926527683     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.6447     Document Type: Article

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