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Volumn 1403, Issue , 2016, Pages 269-284

Development of a SARS coronavirus vaccine from recombinant spike protein plus delta inulin adjuvant

Author keywords

Adjuvant; Advax adjuvant; Baculovirus; CGMP; Coronavirus; Delta inulin; Manufacture; MERS; SARS; Vaccine

Indexed keywords

DELTA INULIN; IMMUNOLOGICAL ADJUVANT; INULIN; RECOMBINANT PROTEIN; SEVERE ACUTE RESPIRATORY SYNDROME VACCINE; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS SPIKE PROTEIN; CORONAVIRUS SPIKE GLYCOPROTEIN; VIRUS VACCINE;

EID: 84963799453     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-3387-7_14     Document Type: Chapter
Times cited : (30)

References (33)
  • 1
    • 0345732171 scopus 로고    scopus 로고
    • SARS: Clinical virology and pathogenesis
    • Nicholls J, Dong XP, Jiang G et al (2003) SARS: clinical virology and pathogenesis. Respirology 8 Suppl:S6–S8
    • (2003) Respirology , vol.8 , pp. S6-S8
    • Nicholls, J.1    Dong, X.P.2    Jiang, G.3
  • 2
    • 0346850741 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome (SARS)— paradigm of an emerging viral infection
    • Berger A, Drosten C, Doerr HW et al (2004) Severe acute respiratory syndrome (SARS)— paradigm of an emerging viral infection. J Clin Virol 29:13–22
    • (2004) J Clin Virol , vol.29 , pp. 13-22
    • Berger, A.1    Drosten, C.2    Doerr, H.W.3
  • 3
    • 84880088201 scopus 로고    scopus 로고
    • Hospital outbreak of Middle East respiratory syndrome coronavirus
    • Assiri A, McGeer A, Perl TM et al (2013) Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med 369:407–416
    • (2013) N Engl J Med , vol.369 , pp. 407-416
    • Assiri, A.1    McGeer, A.2    Perl, T.M.3
  • 4
    • 0038823524 scopus 로고    scopus 로고
    • The Genome sequence of the SARS-associated coronavirus
    • Marra MA, Jones SJ, Astell CR et al (2003) The Genome sequence of the SARS-associated coronavirus. Science 300:1399–1404
    • (2003) Science , vol.300 , pp. 1399-1404
    • Marra, M.A.1    Jones, S.J.2    Astell, C.R.3
  • 5
    • 38449085988 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus infection in vaccinated ferrets
    • Darnell ME, Plant EP, Watanabe H et al (2007) Severe acute respiratory syndrome coronavirus infection in vaccinated ferrets. J Infect Dis 196:1329–1338
    • (2007) J Infect Dis , vol.196 , pp. 1329-1338
    • Darnell, M.E.1    Plant, E.P.2    Watanabe, H.3
  • 6
    • 81255200507 scopus 로고    scopus 로고
    • A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinfl ammatory pulmonary response upon challenge
    • Bolles M, Deming D, Long K et al (2011) A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinfl ammatory pulmonary response upon challenge. J Virol 85: 12201–12215
    • (2011) J Virol , vol.85 , pp. 12201-12215
    • Bolles, M.1    Deming, D.2    Long, K.3
  • 7
    • 33644598311 scopus 로고    scopus 로고
    • Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus
    • See RH, Zakhartchouk AN, Petric M et al (2006) Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. J Gen Virol 87:641–650
    • (2006) J Gen Virol , vol.87 , pp. 641-650
    • See, R.H.1    Zakhartchouk, A.N.2    Petric, M.3
  • 8
    • 58749104040 scopus 로고    scopus 로고
    • Prior immunization with severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein causes severe pneumonia in mice infected with SARSCoV
    • Yasui F, Kai C, Kitabatake M et al (2008) Prior immunization with severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein causes severe pneumonia in mice infected with SARSCoV. J Immunol 181:6337–6348
    • (2008) J Immunol , vol.181 , pp. 6337-6348
    • Yasui, F.1    Kai, C.2    Kitabatake, M.3
  • 9
    • 84859997825 scopus 로고    scopus 로고
    • Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus
    • Tseng CT, Sbrana E, Iwata-Yoshikawa N et al (2012) Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus. PLoS One 7, e35421
    • (2012) Plos One , vol.7
    • Tseng, C.T.1    Sbrana, E.2    Iwata-Yoshikawa, N.3
  • 10
    • 84861392586 scopus 로고    scopus 로고
    • Primary severe acute respiratory syndrome coronavirus infection limits replication but not lung infl ammation upon homologous rechallenge
    • Clay C, Donart N, Fomukong N et al (2012) Primary severe acute respiratory syndrome coronavirus infection limits replication but not lung infl ammation upon homologous rechallenge. J Virol 86:4234–4244
    • (2012) J Virol , vol.86 , pp. 4234-4244
    • Clay, C.1    Donart, N.2    Fomukong, N.3
  • 12
    • 0344395657 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
    • Li W, Moore MJ, Vasilieva N et al (2003) Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 426:450–454
    • (2003) Nature , vol.426 , pp. 450-454
    • Li, W.1    Moore, M.J.2    Vasilieva, N.3
  • 13
    • 8144221600 scopus 로고    scopus 로고
    • CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus
    • Jeffers SA, Tusell SM, Gillim-Ross L et al (2004) CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus. Proc Natl Acad Sci U S A 101:15748–15753
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 15748-15753
    • Jeffers, S.A.1    Tusell, S.M.2    Gillim-Ross, L.3
  • 14
    • 4644338506 scopus 로고    scopus 로고
    • Identifi cation of immunodominant sites on the spike protein of severe acute respiratory syndrome (SARS) coronavirus: Implication for developing SARS diagnostics and vaccines
    • He Y, Zhou Y, Wu H et al (2004) Identifi cation of immunodominant sites on the spike protein of severe acute respiratory syndrome (SARS) coronavirus: implication for developing SARS diagnostics and vaccines. J Immunol 173: 4050–4057
    • (2004) J Immunol , vol.173 , pp. 4050-4057
    • He, Y.1    Zhou, Y.2    Wu, H.3
  • 15
    • 17044375920 scopus 로고    scopus 로고
    • Receptorbinding domain of severe acute respiratory syndrome coronavirus spike protein contains multiple conformation-dependent epitopes that induce highly potent neutralizing antibodies
    • He Y, Lu H, Siddiqui P et al (2005) Receptorbinding domain of severe acute respiratory syndrome coronavirus spike protein contains multiple conformation-dependent epitopes that induce highly potent neutralizing antibodies. J Immunol 174:4908–4915
    • (2005) J Immunol , vol.174 , pp. 4908-4915
    • He, Y.1    Lu, H.2    Siddiqui, P.3
  • 16
    • 34548565790 scopus 로고    scopus 로고
    • Priming with SARS CoV S DNA and boosting with SARS CoV S epitopes specifi c for CD4+ and CD8+ T cells promote cellular immune responses
    • Huang J, Cao Y, Du J et al (2007) Priming with SARS CoV S DNA and boosting with SARS CoV S epitopes specifi c for CD4+ and CD8+ T cells promote cellular immune responses. Vaccine 25:6981–6991
    • (2007) Vaccine , vol.25 , pp. 6981-6991
    • Huang, J.1    Cao, Y.2    Du, J.3
  • 17
    • 33645235641 scopus 로고    scopus 로고
    • A recombinant baculovirus-expressed S glycoprotein vaccine elicits high titers of SARSassociated coronavirus (SARS-CoV) neutralizing antibodies in mice
    • Zhou Z, Post P, Chubet R et al (2006) A recombinant baculovirus-expressed S glycoprotein vaccine elicits high titers of SARSassociated coronavirus (SARS-CoV) neutralizing antibodies in mice. Vaccine 24: 3624–3631
    • (2006) Vaccine , vol.24 , pp. 3624-3631
    • Zhou, Z.1    Post, P.2    Chubet, R.3
  • 19
    • 7044263390 scopus 로고    scopus 로고
    • Vaccine adjuvants: Current state and future trends
    • Petrovsky N, Aguilar JC (2004) Vaccine adjuvants: current state and future trends. Immunol Cell Biol 82:488–496
    • (2004) Immunol Cell Biol , vol.82 , pp. 488-496
    • Petrovsky, N.1    Aguilar, J.C.2
  • 20
    • 84887888030 scopus 로고    scopus 로고
    • The polysaccharide inulin is characterized by an extensive series of periodic isoforms with varying biological actions
    • Cooper PD, Barclay TG, Ginic-Markovic M et al (2013) The polysaccharide inulin is characterized by an extensive series of periodic isoforms with varying biological actions. Glycobiology 23:1164–1174
    • (2013) Glycobiology , vol.23 , pp. 1164-1174
    • Cooper, P.D.1    Barclay, T.G.2    Ginic-Markovic, M.3
  • 21
    • 79953874296 scopus 로고    scopus 로고
    • Delta inulin: A novel, immunologically active, stable packing structure comprising beta-D-[2 -> 1] poly(fructo-furanosyl) alpha-D-glucose polymers
    • Cooper PD, Petrovsky N (2011) Delta inulin: a novel, immunologically active, stable packing structure comprising beta-D-[2 -> 1] poly(fructo-furanosyl) alpha-D-glucose polymers. Glycobiology 21:595–606
    • (2011) Glycobiology , vol.21 , pp. 595-606
    • Cooper, P.D.1    Petrovsky, N.2
  • 22
    • 84864000393 scopus 로고    scopus 로고
    • Advax, a polysaccharide adjuvant derived from delta inulin, provides improved infl uenza vaccine protection through broad-based enhancement of adaptive immune responses
    • Honda-Okubo Y, Saade F, Petrovsky N (2012) Advax, a polysaccharide adjuvant derived from delta inulin, provides improved infl uenza vaccine protection through broad-based enhancement of adaptive immune responses. Vaccine 30:5373–5381
    • (2012) Vaccine , vol.30 , pp. 5373-5381
    • Honda-Okubo, Y.1    Saade, F.2    Petrovsky, N.3
  • 23
    • 77952717965 scopus 로고    scopus 로고
    • An inactivated Vero cell-grown Japanese encephalitis vaccine formulated with Advax, a novel inulin-based adjuvant, induces protective neutralizing antibody against homologous and heterologous fl aviviruses
    • Lobigs M, Pavy M, Hall RA et al (2010) An inactivated Vero cell-grown Japanese encephalitis vaccine formulated with Advax, a novel inulin-based adjuvant, induces protective neutralizing antibody against homologous and heterologous fl aviviruses. J Gen Virol 91: 1407–1417
    • (2010) J Gen Virol , vol.91 , pp. 1407-1417
    • Lobigs, M.1    Pavy, M.2    Hall, R.A.3
  • 24
    • 84897946341 scopus 로고    scopus 로고
    • Advax-adjuvanted recombinant protective antigen provides protection against inhalational anthrax that is further enhanced by addition of murabutide adjuvant
    • Feinen B, Petrovsky N, Verma A et al (2014) Advax-adjuvanted recombinant protective antigen provides protection against inhalational anthrax that is further enhanced by addition of murabutide adjuvant. Clin Vaccine Immunol 21:580–586
    • (2014) Clin Vaccine Immunol , vol.21 , pp. 580-586
    • Feinen, B.1    Petrovsky, N.2    Verma, A.3
  • 25
    • 84920118249 scopus 로고    scopus 로고
    • A single immunization with inactivated H1N1 infl uenza vaccine formulated with delta inulin adjuvant (Advax) overcomes pregnancyassociated immune suppression and enhances passive neonatal protection
    • Honda-Okubo Y, Kolpe A, Li L et al (2014) A single immunization with inactivated H1N1 infl uenza vaccine formulated with delta inulin adjuvant (Advax) overcomes pregnancyassociated immune suppression and enhances passive neonatal protection. Vaccine 32:4651–4659
    • (2014) Vaccine , vol.32 , pp. 4651-4659
    • Honda-Okubo, Y.1    Kolpe, A.2    Li, L.3
  • 26
    • 84875765134 scopus 로고    scopus 로고
    • JE-ADVAX vaccine protection against Japanese encephalitis virus mediated by memory B cells in the absence of CD8+ T cells and preexposure neutralizing antibody
    • Larena M, Prow NA, Hall RA et al (2013) JE-ADVAX vaccine protection against Japanese encephalitis virus mediated by memory B cells in the absence of CD8+ T cells and preexposure neutralizing antibody. J Virol 87:4395–4402
    • (2013) J Virol , vol.87 , pp. 4395-4402
    • Larena, M.1    Prow, N.A.2    Hall, R.A.3
  • 27
    • 80051553818 scopus 로고    scopus 로고
    • Delta inulin polysaccharide adjuvant enhances the ability of split-virion H5N1 vaccine to protect against lethal challenge in ferrets
    • Layton RC, Petrovsky N, Gigliotti AP et al (2011) Delta inulin polysaccharide adjuvant enhances the ability of split-virion H5N1 vaccine to protect against lethal challenge in ferrets. Vaccine 29:6242–6251
    • (2011) Vaccine , vol.29 , pp. 6242-6251
    • Layton, R.C.1    Petrovsky, N.2    Gigliotti, A.P.3
  • 28
    • 84883274590 scopus 로고    scopus 로고
    • An inactivated cell culture Japanese encephalitis vaccine (JE-ADVAX) formulated with delta inulin adjuvant provides robust heterologous protection against West Nile encephalitis via cross-protective memory B cells and neutralizing antibody
    • Petrovsky N, Larena M, Siddharthan V et al (2013) An inactivated cell culture Japanese encephalitis vaccine (JE-ADVAX) formulated with delta inulin adjuvant provides robust heterologous protection against West Nile encephalitis via cross-protective memory B cells and neutralizing antibody. J Virol 87:10324–10333
    • (2013) J Virol , vol.87 , pp. 10324-10333
    • Petrovsky, N.1    Larena, M.2    Siddharthan, V.3
  • 29
    • 84875257910 scopus 로고    scopus 로고
    • A novel hepatitis B vaccine containing Advax, a polysaccharide adjuvant derived from delta inulin, induces robust humoral and cellular immunity with minimal reactogenicity in preclinical testing
    • Saade F, Honda-Okubo Y, Trec S et al (2013) A novel hepatitis B vaccine containing Advax, a polysaccharide adjuvant derived from delta inulin, induces robust humoral and cellular immunity with minimal reactogenicity in preclinical testing. Vaccine 31:1999–2007
    • (2013) Vaccine , vol.31 , pp. 1999-2007
    • Saade, F.1    Honda-Okubo, Y.2    Trec, S.3
  • 30
    • 78651250984 scopus 로고    scopus 로고
    • Induction of mucosal and systemic antibody and T-cell responses following primeboost immunization with novel adjuvanted human immunodefi ciency virus-1-vaccine formulations
    • Cristillo AD, Ferrari MG, Hudacik L et al (2011) Induction of mucosal and systemic antibody and T-cell responses following primeboost immunization with novel adjuvanted human immunodefi ciency virus-1-vaccine formulations. J Gen Virol 92:128–140
    • (2011) J Gen Virol , vol.92 , pp. 128-140
    • Cristillo, A.D.1    Ferrari, M.G.2    Hudacik, L.3
  • 31
    • 84908651646 scopus 로고    scopus 로고
    • Immunogenicity and safety of Advax, a novel polysaccharide adjuvant based on delta inulin, when formulated with hepatitis B surface antigen: A randomized controlled Phase 1 study
    • Gordon D, Kelley P, Heinzel S et al (2014) Immunogenicity and safety of Advax, a novel polysaccharide adjuvant based on delta inulin, when formulated with hepatitis B surface antigen: a randomized controlled Phase 1 study. Vaccine 32(48):6469–6477
    • (2014) Vaccine , vol.32 , Issue.48 , pp. 6469-6477
    • Gordon, D.1    Kelley, P.2    Heinzel, S.3
  • 32
    • 84864008199 scopus 로고    scopus 로고
    • Randomized clinical trial of immunogenicity and safety of a recombinant H1N1/2009 pandemic infl uenza vaccine containing Advax polysaccharide adjuvant
    • Gordon DL, Sajkov D, Woodman RJ et al (2012) Randomized clinical trial of immunogenicity and safety of a recombinant H1N1/2009 pandemic infl uenza vaccine containing Advax polysaccharide adjuvant. Vaccine 30:5407–5416
    • (2012) Vaccine , vol.30 , pp. 5407-5416
    • Gordon, D.L.1    Sajkov, D.2    Woodman, R.J.3
  • 33
    • 84923169092 scopus 로고    scopus 로고
    • Severe acute respiratory syndromeassociated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung eosinophilic immunopathology
    • Honda-Okubo Y, Barnard D, Ong CH et al (2015) Severe acute respiratory syndromeassociated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung eosinophilic immunopathology. J Virol 89:2995–3007
    • (2015) J Virol , vol.89 , pp. 2995-3007
    • Honda-Okubo, Y.1    Barnard, D.2    Ong, C.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.