Revisiting the involvement of signaling gradients in somitogenesis

FEBS Journal

Volumn 283, Issue 8, 2016, Pages 1430-1437

  Mallo, Moisés ^a  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

development; mesoderm; segmentation; signaling; somite formation; vertebrate

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR RECEPTOR 1; RETINOIC ACID; WNT PROTEIN;

DEVELOPMENT; DEVELOPMENTAL STAGE; EMBRYO DEVELOPMENT; EMBRYONAL TISSUE; FGF4 GENE; FGF8 GENE; HUMAN; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; SOMITE; SOMITOGENESIS; TISSUE EXPANSION; ANIMAL; MESODERM; METABOLISM; MORPHOGENESIS; PHYSIOLOGY;

ANIMALS; HUMANS; MESODERM; MORPHOGENESIS; SIGNAL TRANSDUCTION; SOMITES;

EID: 84963795355     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.13622     Document Type: Review

References (24)

1. Aulehla A, &, Pourquié O, (2010) Signaling gradients during paraxial mesoderm development. Cold Spring Harb Perspect Biol 2, a000869.
2. Wilson V, Olivera-Martinez I, &, Storey KG, (2009) Stem cells, signals and vertebrate body axis extension. Development 136, 1591-1604.
3. Aulehla A, &, Herrmann BG, (2004) Segmentation in vertebrates: clock and gradient finally joined. Genes Dev 18, 2060-2067.
4. Aulehla A, Wehrle C, Brand-Saberi B, Kemler R, Gossler A, Kanzler B, &, Herrmann BG, (2003) Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev Cell 4, 395-406.
5. Dequéant ML, Glynn E, Gaudenz K, Wahl M, Chen J, Mushegian A, &, Pourquié O, (2006) A complex oscillating network of signaling genes underlies the mouse segmentation clock. Science 314, 1595-1598.
6. Aulehla A, Wiegraebe W, Baubet V, Wahl MB, Deng C, Taketo M, Lewandoski M, &, Pourquié O, (2008) A beta-catenin gradient links the clock and wavefront systems in mouse embryo segmentation. Nat Cell Biol 10, 186-193.
7. Bajard L, Morelli LG, Ares S, Pécréaux J, Jülicher F, &, Oates AC, (2014) Wnt-regulated dynamics of positional information in zebrafish somitogenesis. Development 141, 1381-1391.
8. Dunty WC Jr, Biris KK, Chalamalasetty RB, Taketo MM, Lewandoski M, &, Yamaguchi TP, (2008) Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development 135, 85-94.
9. Dubrulle J, McGrew MJ, &, Pourquié O, (2001) FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation. Cell 106, 219-232.
10. Dubrulle J, &, Pourquié O, (2004) fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo. Nature 427, 419-422.
11. Sawada A, Shinya M, Jiang YJ, Kawakami A, Kuroiwa A, &, Takeda H, (2001) Fgf/MAPK signalling is a crucial positional cue in somite boundary formation. Development 128, 4873-4880.
12. Wahl MB, Deng C, Lewandoski M, &, Pourquié O, (2007) FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis. Development 134, 4033-4041.
13. Perantoni AO, Timofeeva O, Naillat F, Richman C, Pajni-Underwood S, Wilson C, Vainio S, Dove LF, &, Lewandoski M, (2005) Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development. Development 132, 3859-3871.
14. Bessho Y, Sakata R, Komatsu S, Shiota K, Yamada S, &, Kageyama R, (2001) Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev 15, 2642-2647.
15. Naiche LA, Holder N, &, Lewandoski M, (2011) FGF4 and FGF8 comprise the wavefront activity that controls somitogenesis. Proc Natl Acad Sci USA 108, 4018-4023.
16. Boulet AM, &, Capecchi MR, (2012) Signaling by FGF4 and FGF8 is required for axial elongation of the mouse embryo. Dev Biol 371, 235-245.
17. Sun X, Meyers EN, Lewandoski M, &, Martin GR, (1999) Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. Genes Dev 13, 1834-1846.
18. Sirbu IO, &, Duester G, (2006) Retinoic-acid signalling in node ectoderm and posterior neural plate directs left-right patterning of somitic mesoderm. Nat Cell Biol 8, 271-277.
19. Diez del Corral R, Olivera-Martinez I, Goriely A, Gale E, Maden M, &, Storey K, (2003) Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension. Neuron 40, 65-79.
20. Kumar S, &, Duester G, (2014) Retinoic acid controls body axis extension by directly repressing Fgf8 transcription. Development 141, 2972-2977.
21. Kawakami Y, Raya A, Raya RM, Rodríguez-Esteban C, &, Izpisúa Belmonte JC, (2005) Retinoic acid signalling links left-right asymmetric patterning and bilaterally symmetric somitogenesis in the zebrafish embryo. Nature 435, 165-171.
22. Cunningham TJ, &, Duester G, (2015) Mechanisms of retinoic acid signalling and its roles in organ and limb development. Nat Rev Mol Cell Biol 16, 110-123.
23. Sandell LL, Sanderson BW, Moiseyev G, Johnson T, Mushegian A, Young K, Rey JP, Ma JX, Staehling-Hampton K, &, Trainor PA, (2007) RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. Genes Dev 21, 1113-1124.
24. Cunningham TJ, Brade T, Sandell LL, Lewandoski M, Trainor PA, Colas A, Mercola M, &, Duester G, (2015) Retinoic acid activity in undifferentiated neural progenitors is sufficient to fulfill its role in restricting Fgf8 expression for somitogenesis. PLoS One 10, e0137894.