Genomic landscape of somatic alterations in esophageal squamous cell carcinoma and gastric cancer

Cancer Research

Volumn 76, Issue 7, 2016, Pages 1714-1723

  Hu, Nan ^a   Kadota, Mitsutaka ^a   Liu, Huaitian ^a   Abnet, Christian C ^a   Su, Hua ^a   Wu, Hailong ^a   Freedman, Neal D ^a   Yang, Howard H ^a   Wang, Chaoyu ^a   Yan, Chunhua ^a   Wang, Lemin ^a   Gere, Sheryl ^a   Hutchinson, Amy ^a,b   Song, Guohong ^a   Wang, Yuan ^c   Ding, Ti ^c   Qiao, You Lin ^d   Koshiol, Jill ^a   Dawsey, Sanford M ^a   Giffen, Carol ^e   Goldstein, Alisa M ^a   Taylor, Philip R ^a   Lee, Maxwell P ^a   more..

^a NATIONAL CANCER INSTITUTE   (United States)

^b FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^c SHANXI CANCER HOSPITAL   (China)

^d CANCER HOSPITAL   (China)

^e INFORMATION MANAGEMENT SERVICES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; BRCA2 PROTEIN; CHECKPOINT KINASE 2; CYSTEINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR 2; FRAGILE HISTIDINE TRIAD PROTEIN; GUANINE; JANUS KINASE 3; PROTEIN MSH3; PROTEIN PATCHED;

AMH GENE; AMINO ACID SUBSTITUTION; ARTICLE; BLOOD SAMPLING; BRCA2 GENE; CARDIA; CHEK2 GENE; CHROMOSOME ABERRATION; ERBB2 GENE; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FBXW7 GENE; FGF2 GENE; FHIT GENE; GENE; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENOME; HUMAN; HUMAN TISSUE; JAK3 GENE; KISS1R GENE; MACROD2 GENE; MNX1 GENE; MSH3 GENE; MUTAGENESIS; NF1 GENE; NUCLEOTIDE SEQUENCE; OXIDATION; PARK2 GENE; PRIORITY JOURNAL; PRKRIR GENE; PTCH GENE; STOMACH ADENOCARCINOMA; TUMOR BIOPSY; TUMOR SUPPRESSOR GENE; WNK2 GENE; ESOPHAGUS TUMOR; FEMALE; GENETIC PREDISPOSITION; GENETICS; GENOMICS; MALE; PATHOLOGY; PROCEDURES; SQUAMOUS CELL CARCINOMA; STOMACH TUMOR;

CARCINOMA, SQUAMOUS CELL; ESOPHAGEAL NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOMICS; HUMANS; MALE; STOMACH NEOPLASMS;

EID: 84963748383     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-0338     Document Type: Article

References (25)

1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010;127:2893-917.
2. Ke L. Mortality and incidence trends from esophagus cancer in selected geographic areas of China circa 1970-90. Int J Cancer 2002;102:271-4.
3. Li JY. Epidemiology of esophageal cancer in China. Natl Cancer Inst Monogr 1982;62:113-20.
4. Liu SF, Shen Q, Dawsey SM, Wang GQ, Nieberg RK, Wang ZY, et al. Esophageal balloon cytology and subsequent risk of esophageal and gastric-cardia cancer in a high-risk Chinese population. Int J Cancer 1994;57:775-80.
5. Abnet CC, Freedman ND, Hu N, Wang Z, Yu K, Shu XO, et al. A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. Nat Genet 2010;42:764-7.
6. Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, et al. An integrated genomic analysis of human glioblastoma multiforme. Science 2008;321:1807-12.
7. Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med 2009;360:765-73.
8. Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 2009;361:1058-66.
9. Noushmehr H, Weisenberger DJ, Diefes K, Phillips HS, Pujara K, Berman BP, et al. Identification of aCpGislandmethylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 2010;17:510-22.
10. Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005;310:644-8.
11. Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007;448:561-6.
12. Wang K, Kan J, Yuen ST, Shi ST, Chu KM, Law S, et al. Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer. Nat Genet 2011;43:1219-23.
13. Zang ZJ, Cutcutache I, Poon SL, Zhang SL, McPherson JR, Tao J, et al. Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. Nat Genet 2012;44:570-4.
14. Agrawal N, Jiao Y, Bettegowda C, Hutfless SM, Wang Y, David S, et al. Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma. Cancer Discov 2012;2:899-905.
15. Nagarajan N, Bertrand D, Hillmer AM, Zang ZJ, Yao F, Jacques PE, et al. Whole-genome reconstruction and mutational signatures in gastric cancer. Genome Biol 2012;13:R115.
16. Dulak AM, Stojanov P, Peng S, Lawrence MS, Fox C, Stewart C, et al. Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity. Nat Genet 2013;45:478-86.
17. Wang K, Yuen ST, Xu J, Lee SP, Yan HH, Shi ST, et al. Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. Nat Genet 2014;46:573-82.
18. Song Y, Li L, Ou Y, Gao Z, Li E, Li X, et al. Identification of genomic alterations in oesophageal squamous cell cancer. Nature 2014;509:91-5.
19. Lin DC, Hao JJ, Nagata Y, Xu L, Shang L, Meng X, et al. Genomic and molecular characterization of esophageal squamous cell carcinoma. Nat Genet 2014;46:467-73.
20. Gao YB, Chen ZL, Li JG, Hu XD, Shi XJ, Sun ZM, et al. Genetic landscape of esophageal squamous cell carcinoma. Nat Genet 2014; 46:1097-102.
21. Zhang L, Zhou Y, Cheng C, Cui H, Cheng L, Kong P, et al. Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma. Am J Hum Genet 2015;96:597-611.
22. Bass AJ, Lawrence MS, Brace LE, Ramos AH, Drier Y, Cibulskis K, et al. Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. Nat Genet 2011;43:964-8.
23. Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, et al. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008;321:1801-6.
24. Li M, Zhao H, Zhang X, Wood LD, Anders RA, Choti MA, et al. Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma. Nat Genet 2011;43:828-9.
25. Hu N, Wang C, Ng D, Clifford R, Yang HH, Tang ZZ, et al. Genomic characterization of esophageal squamous cell carcinoma from a high-risk population in China. Cancer Res 2009;69:5908-17.