Recognition of a sequence: more growth before birth, longer telomeres at birth, more lean mass after birth

Pediatric Obesity

Volumn 12, Issue 4, 2017, Pages 274-279

  de Zegher, F ^a   Diaz M ^b   Lopez Bermejo, A ^c,d   Ibanez L ^b,e  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF BARCELONA   (Spain)

^c HOSPITAL JOSEP TRUETA   (Spain)

^d GIRONA BIOMEDICAL RESEARCH INSTITUTE IDIBGI   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

fat mass; fetal growth; lean mass; telomere

Indexed keywords

ADULT; ARTICLE; BODY COMPOSITION; BODY MASS; BODY WEIGHT; BREAST FEEDING; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; GESTATIONAL AGE; GESTATIONAL WEIGHT GAIN; GROWTH RATE; HUMAN; HUMAN CELL; INFANT; LARGE FOR GESTATIONAL AGE; LEAN BODY WEIGHT; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SMALL FOR DATE INFANT; TELOMERE LENGTH; BIRTH WEIGHT; FETUS DEVELOPMENT; GENETICS; METABOLISM; NEWBORN; PHOTON ABSORPTIOMETRY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TELOMERE; WEIGHT GAIN;

ABSORPTIOMETRY, PHOTON; BIRTH WEIGHT; BODY COMPOSITION; BODY MASS INDEX; FEMALE; FETAL DEVELOPMENT; GESTATIONAL AGE; HUMANS; INFANT; INFANT, NEWBORN; INFANT, SMALL FOR GESTATIONAL AGE; MALE; REAL-TIME POLYMERASE CHAIN REACTION; TELOMERE; WEIGHT GAIN;

EID: 84963706503     PISSN: 20476302     EISSN: 20476310     Source Type: Journal    
DOI: 10.1111/ijpo.12137     Document Type: Article

References (26)

1. Armanios M, Blackburn EH. The telomere syndromes. Nat Rev Genet 2012; 13: 693–704.
2. Hjelmborg JB, Dalgård C, Möller S, et al. The heritability of leucocyte telomere length dynamics. J Med Genet 2015; 52: 297–302.
3. Benetos A, Kark JD, Susser E, et al. Tracking and fixed ranking of leukocyte telomere length across the adult life course. Aging Cell 2013; 12: 615–621.
4. Heidinger BJ, Blount JD, Boner W, Griffiths K, Metcalfe NB, Monaghan P. Telomere length in early life predicts lifespan. Proc Natl Acad Sci U S A 2012; 109: 1743–1748.
5. Entringer S, Buss C, Wadhwa PD. Prenatal stress, telomere biology, and fetal programming of health and disease risk. Sci Signal 2012; 5: pt12.
6. Shalev I, Caspi A, Ambler A, et al. Perinatal complications and aging indicators by midlife. Pediatrics 2014; 134: e1315–1323.
7. Hunt SC, Kark JD, Aviv A. Association between shortened leukocyte telomere length and cardio-metabolic outcomes. Circ Cardiovasc Genet 2015; 8: 4–7.
8. Hales CN, Barker DJP, Clark PMS, et al. Foetal and infant growth and impaired glucose tolerance at age 64. BMJ 1991; 303: 1019–1022.
9. Song Y, Huang YT, Song Y, et al. Birthweight, mediating biomarkers and the development of type 2 diabetes later in life: a prospective study of multi-ethnic women. Diabetologia 2015; 58: 1220–1230.
10. Kensara OA, Wootton SA, Phillips DI, Patel M, Jackson AA, Elia M. Hertfordshire Study Group. Foetal programming of body composition: relation between birth weight and body composition measured with dual-energy X-ray absorptiometry and anthropometric methods in older Englishmen. Am J Clin Nutr 2005; 82: 980–987.
11. Bann D, Wills A, Cooper R, et al. Birth weight and growth from infancy to late adolescence in relation to fat and lean mass in early old age: findings from the MRC National Survey of Health and Development. Int J Obes 2014; 38: 69–75.
12. Dodds R, Denison HJ, Ntani G, et al. Birth weight and muscle strength: a systematic review and meta-analysis. J Nutr 2012; 16: 609–615.
13. de Zegher F, Pérez-Cruz M, Díaz M, Gómez-Roig MD, López-Bermejo A, Ibáñez L. Less myostatin and more lean mass in large-born infants from nondiabetic mothers. J Clin Endocrinol Metab 2014; 99: E2367–2371.
14. Okuda K, Bardeguez A, Gardner JP, et al. Telomere length in the newborn. Pediatr Res 2002; 52: 377–381.
15. Kajantie E, Pietiläinen KH, Wehkalampi K, et al. No association between body size at birth and leucocyte telomere length in adult life – evidence from three cohort studies. Int J Epidemiol 2012; 41: 1400–1408.
16. Tellechea M, Gianotti TF, Alvariñas J, González CD, Sookoian S, Pirola CJ. Telomere length in the two extremes of abnormal fetal growth and the programming effect of maternal arterial hypertension. Sci Rep 2015; 5: 7869.
17. Strohmaier J, van Dongen J, Willemsen G, et al. Low birthweight in monozygotic twins discordant for birth weight is associated with shorter telomere length and lower IQ, but not anxiety/depression in later life. Twin Res Hum Genet 2015; 18: 198–209.
18. de Zegher F, Sebastiani G, Díaz M, Sánchez-Infantes D, López-Bermejo A, Ibáñez L. Body composition and circulating high-molecular-weight adiponectin and IGF-I in infants born small for gestational age: breast- versus formula-feeding. Diabetes 2012; 61: 1969–1973.
19. de Zegher F, Sebastiani G, Diaz M, Gómez-Roig MD, López-Bermejo A, Ibáñez L. Breast-feeding vs formula-feeding for infants born small-for-gestational-age: divergent effects on fat mass and on circulating IGF-I and high-molecular-weight adiponectin in late infancy. J Clin Endocrinol Metab 2013; 98: 1242–1247.
20. Cawthon RM. Telomere measurement by quantitative PCR. Nucleic Acids Res 2002; 30: e47.
21. Elks CE, Heude B, de Zegher F, et al. Associations between genetic obesity susceptibility and early postnatal fat and lean mass: an individual participant meta-analysis. JAMA Pediatr 2014; 168: 1122–1130.
22. Marzetti E, Lorenzi M, Antocicco M, et al. Shorter telomeres in peripheral blood mononuclear cells from older persons with sarcopenia: results from an exploratory study. Front Aging Neurosci 2014; 6: 233.
23. Woo J, Yu R, Tang N, Leung J. Telomere length is associated with decline in grip strength in older persons aged 65 years and over. Age 2014; 36: 9711.
24. Ye J, Renault VM, Jamet K, Gilson E. Transcriptional outcome of telomere signalling. Nat Rev Genet 2014; 15: 491–503.
25. Hallows SE, Regnault TR, Betts DH. The long and short of it: the role of telomeres in fetal origins of adult disease. J Pregnancy 2012; 2012: 638476.
26. de Zegher F, Díaz M, Ibáñez L. Longer telomeres after insulin sensitization in adolescent girls with hyperinsulinemic androgen excess. JAMA Pediatr 2015; 169: 787–788.