Associations between genetic obesity susceptibility and early postnatal fat and lean mass: An individual participant meta-analysis

JAMA Pediatrics

Volumn 168, Issue 12, 2014, Pages 1122-1130

  Elks, Cathy E ^a   Heude, Barbara ^b,c   De Zegher, Francis ^d   Barton, Sheila J ^e   Clément, Karine ^f,g   Inskip, Hazel M ^e   Koudou, Yves ^b,c   Cooper, Cyrus ^e,h   Dunger, David B ⁱ   Ibáñez, Lourdes ^j,k   Charles, Marie Aline ^b,c   Ong, Ken K ^a,i  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b INSERM   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^g Institut National de l a Santé et de la Recherche Médicale   (France)

^h UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

ⁱ UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^j UNIVERSITY OF BARCELONA   (Spain)

^k INSTITUTO DE SALUD CARLOS III   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALLELE; ARTICLE; BIRTH; BODY COMPOSITION; BODY FAT; BODY HEIGHT; BODY MASS; BODY SIZE; BODY WEIGHT; FAT MASS; FEMALE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; META ANALYSIS; OBESITY; PERINATAL PERIOD; PRIORITY JOURNAL; SYSTEMATIC REVIEW; ADIPOSE TISSUE; FRANCE; GENETIC PREDISPOSITION; GENETICS; INFANT; PRESCHOOL CHILD; RISK FACTOR; SPAIN; UNITED KINGDOM;

ADIPOSE TISSUE; BODY WEIGHT; CHILD, PRESCHOOL; ENGLAND; FEMALE; FRANCE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT; MALE; OBESITY; RISK FACTORS; SPAIN;

EID: 84930734898     PISSN: 21686203     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamapediatrics.2014.1619     Document Type: Article

References (32)

1. Lakshman R, Elks CE, Ong KK. Childhood obesity. Circulation. 2012;126(14):1770-1779.
2. Baird J, Fisher D, Lucas P, Kleijnen J, Roberts H, Law C. Being big or growing fast: systematic review of size and growth in infancy and later obesity. BMJ. 2005;331(7522):929. doi:10.1136/bmj.38586.411273.E0.
3. Druet C, Stettler N, Sharp S, et al. Prediction of childhood obesity by infancy weight gain: an individual-level meta-analysis. Paediatr Perinat Epidemiol. 2012;26(1):19-26.
4. Adair LS, Fall CHD, Osmond C, et al; COHORTS group. Associations of linear growth and relative weight gain during early life with adult health and human capital in countries of low and middle income: findings from five birth cohort studies. Lancet. 2013;382(9891):525-534.
5. Wells JCK, Chomtho S, Fewtrell MS. Programming of body composition by early growth and nutrition. Proc Nutr Soc. 2007;66(3):423-434.
6. Elks CE, Loos RJF, Sharp SJ, et al. Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth. PLoS Med. 2010;7(5):e1000284. doi:10.1371/journal.pmed.1000284.
7. Warrington NM, Howe LD, Wu YY, et al. Association of a body mass index genetic risk score with growth throughout childhood and adolescence. PLoS One. 2013;8(11):e79547. doi:10.1371/journal.pone.0079547.
8. Belsky DW, Moffitt TE, Houts R, et al. Polygenic risk, rapid childhood growth, and the development of obesity: evidence from a 4-decade longitudinal study. Arch Pediatr Adolesc Med. 2012;166(6):515-521.
9. Speliotes EK, Willer CJ, Berndt SI, et al MAGIC Procardis Consortium. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010;42(11):937-948.
10. Ong KK, Langkamp M, Ranke MB, et al. Insulin-like growth factor I concentrations in infancy predict differential gains in body length and adiposity: the Cambridge Baby Growth Study. Am J Clin Nutr. 2009;90(1):156-161.
11. Inskip HM, Godfrey KM, Robinson SM, Law CM, Barker DJP, Cooper C; SWS Study Group. Cohort profile: the Southampton Women's Survey. Int J Epidemiol. 2006;35(1):42-48.
12. Robinson S, Marriott L, Poole J, et al; Southampton Women's Survey Study Group. Dietary patterns in infancy: the importance of maternal and family influences on feeding practice. Br J Nutr. 2007;98(5):1029-1037.
13. Moon RJ, Harvey NC, Robinson SM, et al SWS Study Group. Maternal plasma polyunsaturated fatty acid status in late pregnancy is associated with offspring body composition in childhood. J Clin Endocrinol Metab. 2013;98(1):299-307.
14. Drouillet P, Forhan A, De Lauzon-Guillain B, et al. Maternal fatty acid intake and fetal growth: evidence for an association in overweight women: the "EDEN mother-child" cohort (study of pre- and early postnatal determinants of the child's development and health). Br J Nutr. 2009;101(4):583-591.
15. López-Bermejo A, Petry CJ, Díaz M, et al. The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks. J Clin Endocrinol Metab. 2008;93(4):1501-1505.
16. Goran MI, Kaskoun MC, Carpenter WH, Poehlman ET, Ravussin E, Fontvieille AM. Estimating body composition of young children by using bioelectrical resistance. J Appl Physiol (1985). 1993;75(4):1776-1780.
17. Brook CG. Determination of body composition of children from skinfold measurements. Arch Dis Child. 1971;46(246):182-184.
18. Li S, Zhao JH, Luan J, et al. Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies. Am J Clin Nutr. 2010;91(1):184-190.
19. Freeman JV, Cole TJ, Chinn S, Jones PR, White EM, Preece MA. Cross sectional stature and weight reference curves for the UK, 1990. Arch Dis Child. 1995;73(1):17-24.
20. Mei H, ChenW, Jiang F, et al. Longitudinal replication studies of GWAS risk SNPs influencing body mass index over the course of childhood and adulthood. PLoS One. 2012;7(2):e31470. doi:10.1371/journal.pone.0031470.
21. Sovio U, Mook-Kanamori DO, Warrington NM, et al; Early Growth Genetics Consortium. Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development. PLoS Genet. 2011;7(2):e1001307. doi:10.1371/journal.pgen.1001307.
22. Elks CE, Perry JR, Sulem P, et al GIANT Consortium. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet. 2010;42(12):1077-1085.
23. Wells JCK, Hallal PC,Wright A, Singhal A, Victora CG. Fetal, infant and childhood growth: relationships with body composition in Brazilian boys aged 9 years. Int J Obes (Lond). 2005;29(10):1192-1198.
24. Wilson HJ, Dickinson F, Hoffman DJ, Griffiths PL, Bogin B, Varela-Silva MI. Fat free mass explains the relationship between stunting and energy expenditure in urban Mexican Maya children. Ann Hum Biol. 2012;39(5):432-439.
25. Walker SP, Gaskin P, Powell CA, Bennett FI, Forrester TE, Grantham-McGregor S. The effects of birth weight and postnatal linear growth retardation on blood pressure at age 11-12 years. J Epidemiol Community Health. 2001;55(6):394-398.
26. Gale C, Logan KM, Santhakumaran S, Parkinson JRC, Hyde MJ, Modi N. Effect of breastfeeding compared with formula feeding on infant body composition: a systematic review and meta-analysis. Am J Clin Nutr. 2012;95(3):656-669.
27. Han DY, Murphy R, Morgan AR, et al. Reduced genetic influence on childhood obesity in small for gestational age children. BMC Med Genet. 2013;14:10. doi:10.1186/1471-2350-14-10.
28. Kilpeläinen TO, den Hoed M, Ong KK, et al Early Growth Genetics Consortium. Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals. Am J Clin Nutr. 2011;93(4):851-860.
29. Heid IM, Jackson AU, Randall JC, et al; MAGIC. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet. 2010;42(11):949-960.
30. Wells JCK, Cole TJ; ALSPAC study steam. Adjustment of fat-free mass and fat mass for height in children aged 8 y. Int J Obes RelatMetab Disord. 2002;26(7):947-952.
31. Llewellyn CH, Trzaskowski M, van Jaarsveld CHM, Plomin R,Wardle J. Satiety mechanisms in genetic risk of obesity. JAMA Pediatr. 2014;168(4):338-344.
32. Karlberg J. A biologically-oriented mathematical model (ICP) for human growth. Acta Paediatr Scand Suppl. 1989;350:70-94.