-
1
-
-
77949495196
-
The RNA polymerase I transcription machinery: An emerging target for the treatment of cancer
-
Drygin, D., Rice, W. G., and Grummt, I. (2010) The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer. Annu. Rev. Pharmacol. Toxicol. 50, 131-156
-
(2010)
Annu. Rev. Pharmacol. Toxicol.
, vol.50
, pp. 131-156
-
-
Drygin, D.1
Rice, W.G.2
Grummt, I.3
-
2
-
-
78649336111
-
The nucleolus under stress
-
Boulon, S., Westman, B. J., Hutten, S., Boisvert, F. M., and Lamond, A. I. (2010) The nucleolus under stress. Mol. Cell 40, 216-227
-
(2010)
Mol. Cell
, vol.40
, pp. 216-227
-
-
Boulon, S.1
Westman, B.J.2
Hutten, S.3
Boisvert, F.M.4
Lamond, A.I.5
-
3
-
-
49249139050
-
The post-transcriptional steps of eukaryotic ribosome biogenesis
-
Henras, A. K., Soudet, J., Gérus, M., Lebaron, S., Caizergues-Ferrer, M., Mougin, A., and Henry, Y. (2008) The post-transcriptional steps of eukaryotic ribosome biogenesis. Cell. Mol. Life Sci. 65, 2334-2359
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 2334-2359
-
-
Henras, A.K.1
Soudet, J.2
Gérus, M.3
Lebaron, S.4
Caizergues-Ferrer, M.5
Mougin, A.6
Henry, Y.7
-
4
-
-
64049107857
-
Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction
-
Fumagalli, S., Di Cara, A., Neb-Gulati, A., Natt, F., Schwemberger, S., Hall, J., Babcock, G. F., Bernardi, R., Pandolfi, P. P., and Thomas, G. (2009) Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction. Nat. Cell Biol. 11, 501-508
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 501-508
-
-
Fumagalli, S.1
Di Cara, A.2
Neb-Gulati, A.3
Natt, F.4
Schwemberger, S.5
Hall, J.6
Babcock, G.F.7
Bernardi, R.8
Pandolfi, P.P.9
Thomas, G.10
-
5
-
-
20444383489
-
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron
-
Honda, K., Smith, M. A., Zhu, X., Baus, D., Merrick, W. C., Tartakoff, A. M., Hattier, T., Harris, P. L., Siedlak, S. L., Fujioka, H., Liu, Q., Moreira, P. I., Miller, F. P., Nunomura, A., Shimohama, S., and Perry, G. (2005) Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J. Biol. Chem. 280, 20978-20986
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20978-20986
-
-
Honda, K.1
Smith, M.A.2
Zhu, X.3
Baus, D.4
Merrick, W.C.5
Tartakoff, A.M.6
Hattier, T.7
Harris, P.L.8
Siedlak, S.L.9
Fujioka, H.10
Liu, Q.11
Moreira, P.I.12
Miller, F.P.13
Nunomura, A.14
Shimohama, S.15
Perry, G.16
-
6
-
-
27144494994
-
Ribosome dysfunction is an early event in Alzheimer's disease
-
Ding, Q., Markesbery, W. R., Chen, Q., Li, F., and Keller, J. N. (2005) Ribosome dysfunction is an early event in Alzheimer's disease. J. Neurosci. 25, 9171-9175
-
(2005)
J. Neurosci
, vol.25
, pp. 9171-9175
-
-
Ding, Q.1
Markesbery, W.R.2
Chen, Q.3
Li, F.4
Keller, J.N.5
-
7
-
-
78651486982
-
Nucleolar disruption in dopaminergic neurons leads to oxidative damage and Parkinsonism through repression of mammalian target of rapamycin signaling
-
Rieker, C., Engblom, D., Kreiner, G., Domanskyi, A., Schober, A., Stotz, S., Neumann, M., Yuan, X., Grummt, I., Schütz, G., and Parlato, R. (2011) Nucleolar disruption in dopaminergic neurons leads to oxidative damage and Parkinsonism through repression of mammalian target of rapamycin signaling. J. Neurosci. 31, 453-460
-
(2011)
J. Neurosci
, vol.31
, pp. 453-460
-
-
Rieker, C.1
Engblom, D.2
Kreiner, G.3
Domanskyi, A.4
Schober, A.5
Stotz, S.6
Neumann, M.7
Yuan, X.8
Grummt, I.9
Schütz, G.10
Parlato, R.11
-
8
-
-
84859965734
-
Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6
-
Vilotti, S., Codrich, M., Dal Ferro, M., Pinto, M., Ferrer, I., Collavin, L., Gustincich, S., and Zucchelli, S. (2012) Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6. PLoS ONE 7, e35051
-
(2012)
PLoS ONE
, vol.7
-
-
Vilotti, S.1
Codrich, M.2
Dal Ferro, M.3
Pinto, M.4
Ferrer, I.5
Collavin, L.6
Gustincich, S.7
Zucchelli, S.8
-
9
-
-
84908519127
-
Repression of rRNA transcription by PARIS contributes to Parkinson's disease
-
Kang, H., and Shin, J. H. (2015) Repression of rRNA transcription by PARIS contributes to Parkinson's disease. Neurobiol. Dis. 73, 220-228
-
(2015)
Neurobiol. Dis.
, vol.73
, pp. 220-228
-
-
Kang, H.1
Shin, J.H.2
-
10
-
-
80053947681
-
Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease
-
Lee, J., Hwang, Y. J., Boo, J. H., Han, D., Kwon, O. K., Todorova, K., Kowall, N. W., Kim, Y., and Ryu, H. (2011) Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease. Cell Death Differ. 18, 1726-1735
-
(2011)
Cell Death Differ
, vol.18
, pp. 1726-1735
-
-
Lee, J.1
Hwang, Y.J.2
Boo, J.H.3
Han, D.4
Kwon, O.K.5
Todorova, K.6
Kowall, N.W.7
Kim, Y.8
Ryu, H.9
-
11
-
-
84879068547
-
Expression of expanded CAG transcripts triggers nucleolar stress in Huntington's disease
-
Tsoi, H., and Chan, H. Y. (2013) Expression of expanded CAG transcripts triggers nucleolar stress in Huntington's disease. Cerebellum 12, 310-312
-
(2013)
Cerebellum
, vol.12
, pp. 310-312
-
-
Tsoi, H.1
Chan, H.Y.2
-
12
-
-
84896259966
-
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
-
Haeusler, A. R., Donnelly, C. J., Periz, G., Simko, E. A., Shaw, P. G., Kim, M. S., Maragakis, N. J., Troncoso, J. C., Pandey, A., Sattler, R., Rothstein, J. D., and Wang, J. (2014) C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature 507, 195-200
-
(2014)
Nature
, vol.507
, pp. 195-200
-
-
Haeusler, A.R.1
Donnelly, C.J.2
Periz, G.3
Simko, E.A.4
Shaw, P.G.5
Kim, M.S.6
Maragakis, N.J.7
Troncoso, J.C.8
Pandey, A.9
Sattler, R.10
Rothstein, J.D.11
Wang, J.12
-
13
-
-
84907221451
-
Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
-
Kwon, I., Xiang, S., Kato, M., Wu, L., Theodoropoulos, P., Wang, T., Kim, J., Yun, J., Xie, Y., and McKnight, S. L. (2014) Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells. Science 345, 1139-1145
-
(2014)
Science
, vol.345
, pp. 1139-1145
-
-
Kwon, I.1
Xiang, S.2
Kato, M.3
Wu, L.4
Theodoropoulos, P.5
Wang, T.6
Kim, J.7
Yun, J.8
Xie, Y.9
McKnight, S.L.10
-
14
-
-
66449083254
-
Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome
-
Armistead, J., Khatkar, S., Meyer, B., Mark, B. L., Patel, N., Coghlan, G., Lamont, R. E., Liu, S., Wiechert, J., Cattini, P. A., Koetter, P., Wrogemann, K., Greenberg, C. R., Entian, K. D., Zelinski, T., and Triggs-Raine, B. (2009) Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome. Am. J. Hum. Genet. 84, 728-739
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 728-739
-
-
Armistead, J.1
Khatkar, S.2
Meyer, B.3
Mark, B.L.4
Patel, N.5
Coghlan, G.6
Lamont, R.E.7
Liu, S.8
Wiechert, J.9
Cattini, P.A.10
Koetter, P.11
Wrogemann, K.12
Greenberg, C.R.13
Entian, K.D.14
Zelinski, T.15
Triggs-Raine, B.16
-
15
-
-
84908031921
-
A novel ribosomopathy caused by dysfunction of RPL10 disrupts neurodevelopment and causes X-linked microcephaly in humans
-
Brooks, S. S., Wall, A. L., Golzio, C., Reid, D. W., Kondyles, A., Willer, J. R., Botti, C., Nicchitta, C. V., Katsanis, N., and Davis, E. E. (2014) A novel ribosomopathy caused by dysfunction of RPL10 disrupts neurodevelopment and causes X-linked microcephaly in humans. Genetics 198, 723-733
-
(2014)
Genetics
, vol.198
, pp. 723-733
-
-
Brooks, S.S.1
Wall, A.L.2
Golzio, C.3
Reid, D.W.4
Kondyles, A.5
Willer, J.R.6
Botti, C.7
Nicchitta, C.V.8
Katsanis, N.9
Davis, E.E.10
-
16
-
-
79955955059
-
MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation
-
Singleton, M. K., Gonzales, M. L., Leung, K. N., Yasui, D. H., Schroeder, D. I., Dunaway, K., and LaSalle, J. M. (2011) MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation. Neurobiol. Dis. 43, 190-200
-
(2011)
Neurobiol. Dis.
, vol.43
, pp. 190-200
-
-
Singleton, M.K.1
Gonzales, M.L.2
Leung, K.N.3
Yasui, D.H.4
Schroeder, D.I.5
Dunaway, K.6
LaSalle, J.M.7
-
17
-
-
70350674351
-
Imprinting regulates mammalian snoRNA-encoding chromatin decondensation and neuronal nucleolar size
-
Leung, K. N., Vallero, R. O., DuBose, A. J., Resnick, J. L., and LaSalle, J. M. (2009) Imprinting regulates mammalian snoRNA-encoding chromatin decondensation and neuronal nucleolar size. Hum. Mol. Gen. 18, 4227-4238
-
(2009)
Hum. Mol. Gen.
, vol.18
, pp. 4227-4238
-
-
Leung, K.N.1
Vallero, R.O.2
DuBose, A.J.3
Resnick, J.L.4
LaSalle, J.M.5
-
18
-
-
77951196062
-
Cohesinopathies, gene expression, and chromatin organization
-
Bose, T., and Gerton, J. L. (2010) Cohesinopathies, gene expression, and chromatin organization. J. Cell Biol. 189, 201-210
-
(2010)
J. Cell Biol.
, vol.189
, pp. 201-210
-
-
Bose, T.1
Gerton, J.L.2
-
19
-
-
44649178636
-
Inhibition of nucleolar transcription as a trigger for neuronal apoptosis
-
Kalita, K., Makonchuk, D., Gomes, C., Zheng, J. J., and Hetman, M. (2008) Inhibition of nucleolar transcription as a trigger for neuronal apoptosis. J. Neurochem. 105, 2286-2299
-
(2008)
J. Neurochem.
, vol.105
, pp. 2286-2299
-
-
Kalita, K.1
Makonchuk, D.2
Gomes, C.3
Zheng, J.J.4
Hetman, M.5
-
20
-
-
58149379611
-
Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice
-
Parlato, R., Kreiner, G., Erdmann, G., Rieker, C., Stotz, S., Savenkova, E., Berger, S., Grummt, I., and Schütz, G. (2008) Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice. J. Neurosci. 28, 12759-12764
-
(2008)
J. Neurosci
, vol.28
, pp. 12759-12764
-
-
Parlato, R.1
Kreiner, G.2
Erdmann, G.3
Rieker, C.4
Stotz, S.5
Savenkova, E.6
Berger, S.7
Grummt, I.8
Schütz, G.9
-
21
-
-
84885400581
-
A neuroprotective phase precedes striatal degeneration upon nucleolar stress
-
Kreiner, G., Bierhoff, H., Armentano, M., Rodriguez-Parkitna, J., Sowodniok, K., Naranjo, J. R., Bonfanti, L., Liss, B., Schütz, G., Grummt, I., and Parlato, R. (2013) A neuroprotective phase precedes striatal degeneration upon nucleolar stress. Cell Death Differ. 20, 1455-1464
-
(2013)
Cell Death Differ
, vol.20
, pp. 1455-1464
-
-
Kreiner, G.1
Bierhoff, H.2
Armentano, M.3
Rodriguez-Parkitna, J.4
Sowodniok, K.5
Naranjo, J.R.6
Bonfanti, L.7
Liss, B.8
Schütz, G.9
Grummt, I.10
Parlato, R.11
-
22
-
-
79953020739
-
RNA polymerase 1-driven transcription as a mediator of BDNF-induced neurite outgrowth
-
Gomes, C., Smith, S. C., Youssef, M. N., Zheng, J. J., Hagg, T., and Hetman, M. (2011) RNA polymerase 1-driven transcription as a mediator of BDNF-induced neurite outgrowth. J. Biol. Chem. 286, 4357-4363
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 4357-4363
-
-
Gomes, C.1
Smith, S.C.2
Youssef, M.N.3
Zheng, J.J.4
Hagg, T.5
Hetman, M.6
-
23
-
-
38949170601
-
Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function
-
Jones, N. C., Lynn, M. L., Gaudenz, K., Sakai, D., Aoto, K., Rey, J. P., Glynn, E. F., Ellington, L., Du, C., Dixon, J., Dixon, M. J., and Trainor, P. A. (2008) Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function. Nat. Med. 14, 125-133
-
(2008)
Nat. Med.
, vol.14
, pp. 125-133
-
-
Jones, N.C.1
Lynn, M.L.2
Gaudenz, K.3
Sakai, D.4
Aoto, K.5
Rey, J.P.6
Glynn, E.F.7
Ellington, L.8
Du, C.9
Dixon, J.10
Dixon, M.J.11
Trainor, P.A.12
-
24
-
-
84908150999
-
Nucleolar stress with and without p53
-
James, A., Wang, Y., Raje, H., Rosby, R., and DiMario, P. (2014) Nucleolar stress with and without p53. Nucleus 5, 402-426
-
(2014)
Nucleus
, vol.5
, pp. 402-426
-
-
James, A.1
Wang, Y.2
Raje, H.3
Rosby, R.4
DiMario, P.5
-
25
-
-
0034717122
-
Like attracts like: Getting RNA processing together in the nucleus
-
Lewis, J. D., and Tollervey, D. (2000) Like attracts like: getting RNA processing together in the nucleus. Science 288, 1385-1389
-
(2000)
Science
, vol.288
, pp. 1385-1389
-
-
Lewis, J.D.1
Tollervey, D.2
-
26
-
-
30544449810
-
Control of dendritic arborization by the phosphoinositide-3′-kinase-Akt-mammalian target of rapamycin pathway
-
Jaworski, J., Spangler, S., Seeburg, D. P., Hoogenraad, C. C., and Sheng, M. (2005) Control of dendritic arborization by the phosphoinositide-3′-kinase-Akt-mammalian target of rapamycin pathway. J. Neurosci. 25, 11300-11312
-
(2005)
J. Neurosci
, vol.25
, pp. 11300-11312
-
-
Jaworski, J.1
Spangler, S.2
Seeburg, D.P.3
Hoogenraad, C.C.4
Sheng, M.5
-
27
-
-
34047107208
-
Liprinα1 degradation by calcium/calmodulin-dependent protein kinase II regulates LAR receptor tyrosine phosphatase distribution and dendrite development
-
Hoogenraad, C. C., Feliu-Mojer, M. I., Spangler, S. A., Milstein, A. D., Dunah, A. W., Hung, A. Y., and Sheng, M. (2007) Liprinα1 degradation by calcium/calmodulin-dependent protein kinase II regulates LAR receptor tyrosine phosphatase distribution and dendrite development. Dev. Cell 12, 587-602
-
(2007)
Dev. Cell
, vol.12
, pp. 587-602
-
-
Hoogenraad, C.C.1
Feliu-Mojer, M.I.2
Spangler, S.A.3
Milstein, A.D.4
Dunah, A.W.5
Hung, A.Y.6
Sheng, M.7
-
28
-
-
34249096783
-
Intranucleolar sites of ribosome biogenesis defined by the localization of early binding ribosomal proteins
-
Krüger, T., Zentgraf, H., and Scheer, U. (2007) Intranucleolar sites of ribosome biogenesis defined by the localization of early binding ribosomal proteins. J. Cell Biol. 177, 573-578
-
(2007)
J. Cell Biol.
, vol.177
, pp. 573-578
-
-
Krüger, T.1
Zentgraf, H.2
Scheer, U.3
-
29
-
-
33749162839
-
Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity
-
Kalita, K., Kharebava, G., Zheng, J. J., and Hetman, M. (2006) Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity. J. Neurosci. 26, 10020-10032
-
(2006)
J. Neurosci
, vol.26
, pp. 10020-10032
-
-
Kalita, K.1
Kharebava, G.2
Zheng, J.J.3
Hetman, M.4
-
30
-
-
33644870579
-
A change in the selective translocation of the kinesin-1 motor domain marks the initial specification of the axon
-
Jacobson, C., Schnapp, B., and Banker, G. A. (2006) A change in the selective translocation of the kinesin-1 motor domain marks the initial specification of the axon. Neuron 49, 797-804
-
(2006)
Neuron
, vol.49
, pp. 797-804
-
-
Jacobson, C.1
Schnapp, B.2
Banker, G.A.3
-
31
-
-
24944521658
-
GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking
-
Hoogenraad, C. C., Milstein, A. D., Ethell, I. M., Henkemeyer, M., and Sheng, M. (2005) GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking. Nat. Neurosci. 8, 906-915
-
(2005)
Nat. Neurosci
, vol.8
, pp. 906-915
-
-
Hoogenraad, C.C.1
Milstein, A.D.2
Ethell, I.M.3
Henkemeyer, M.4
Sheng, M.5
-
32
-
-
33644877643
-
NMDA neuroprotection against a phosphatidylinositol-3 kinase inhibitor, LY294002, by NR2B-mediated suppression of glycogen synthase kinase-3β-induced apoptosis
-
Habas, A., Kharebava, G., Szatmari, E., and Hetman, M. (2006) NMDA neuroprotection against a phosphatidylinositol-3 kinase inhibitor, LY294002, by NR2B-mediated suppression of glycogen synthase kinase-3β-induced apoptosis. J. Neurochem. 96, 335-348
-
(2006)
J. Neurochem.
, vol.96
, pp. 335-348
-
-
Habas, A.1
Kharebava, G.2
Szatmari, E.3
Hetman, M.4
-
33
-
-
63949084607
-
SUnSET, a nonradioactive method to monitor protein synthesis
-
Schmidt, E. K., Clavarino, G., Ceppi, M., and Pierre, P. (2009) SUnSET, a nonradioactive method to monitor protein synthesis. Nat. Methods 6, 275-277
-
(2009)
Nat. Methods
, vol.6
, pp. 275-277
-
-
Schmidt, E.K.1
Clavarino, G.2
Ceppi, M.3
Pierre, P.4
-
34
-
-
84862908426
-
Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin
-
Liu, J., Xu, Y., Stoleru, D., and Salic, A. (2012) Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin. Proc. Natl. Acad. Sci. U.S.A. 109, 413-418
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 413-418
-
-
Liu, J.1
Xu, Y.2
Stoleru, D.3
Salic, A.4
-
35
-
-
0033529638
-
Neuroprotection by brain-derived neurotrophic factor is mediated by extracellularsignal-regulated kinase and phosphatidylinositol 3-kinase
-
Hetman, M., Kanning, K., Cavanaugh, J. E., and Xia, Z. (1999) Neuroprotection by brain-derived neurotrophic factor is mediated by extracellularsignal-regulated kinase and phosphatidylinositol 3-kinase. J. Biol. Chem. 274, 22569-22580
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22569-22580
-
-
Hetman, M.1
Kanning, K.2
Cavanaugh, J.E.3
Xia, Z.4
-
36
-
-
79952589652
-
TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1
-
McDonald, K. K., Aulas, A., Destroismaisons, L., Pickles, S., Beleac, E., Camu, W., Rouleau, G. A., and Vande Velde, C. (2011) TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1. Hum. Mol. Genet. 20, 1400-1410
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1400-1410
-
-
McDonald, K.K.1
Aulas, A.2
Destroismaisons, L.3
Pickles, S.4
Beleac, E.5
Camu, W.6
Rouleau, G.A.7
Vande Velde, C.8
-
37
-
-
28844498390
-
New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales
-
Wearne, S. L., Rodriguez, A., Ehlenberger, D. B., Rocher, A. B., Henderson, S. C., and Hof, P. R. (2005) New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales. Neuroscience 136, 661-680
-
(2005)
Neuroscience
, vol.136
, pp. 661-680
-
-
Wearne, S.L.1
Rodriguez, A.2
Ehlenberger, D.B.3
Rocher, A.B.4
Henderson, S.C.5
Hof, P.R.6
-
38
-
-
0037108268
-
N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
-
Knoepfler, P. S., Cheng, P. F., and Eisenman, R. N. (2002) N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev. 16, 2699-2712
-
(2002)
Genes Dev.
, vol.16
, pp. 2699-2712
-
-
Knoepfler, P.S.1
Cheng, P.F.2
Eisenman, R.N.3
-
39
-
-
17744400301
-
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis
-
Boon, K., Caron, H. N., van Asperen, R., Valentijn, L., Hermus, M. C., van Sluis, P., Roobeek, I., Weis, I., Voûte, P. A., Schwab, M., and Versteeg, R. (2001) N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J. 20, 1383-1393
-
(2001)
EMBO J
, vol.20
, pp. 1383-1393
-
-
Boon, K.1
Caron, H.N.2
Van Asperen, R.3
Valentijn, L.4
Hermus, M.C.5
Van Sluis, P.6
Roobeek, I.7
Weis, I.8
Voûte, P.A.9
Schwab, M.10
Versteeg, R.11
-
40
-
-
0023073799
-
Directions in neurogenetic gradients and patterns of anatomical connections in the telencephalon
-
Bayer, S. A., and Altman, J. (1987) Directions in neurogenetic gradients and patterns of anatomical connections in the telencephalon. Prog. Neurobiol. 29, 57-106
-
(1987)
Prog. Neurobiol
, vol.29
, pp. 57-106
-
-
Bayer, S.A.1
Altman, J.2
-
41
-
-
84884217072
-
Conserved regulators of nucleolar size revealed by global phenotypic analyses
-
Neumüller, R. A., Gross, T., Samsonova, A. A., Vinayagam, A., Buckner, M., Founk, K., Hu, Y., Sharifpoor, S., Rosebrock, A. P., Andrews, B., Winston, F., and Perrimon, N. (2013) Conserved regulators of nucleolar size revealed by global phenotypic analyses. Sci. Signal. 6, ra70
-
(2013)
Sci. Signal
, vol.6
, pp. ra70
-
-
Neumüller, R.A.1
Gross, T.2
Samsonova, A.A.3
Vinayagam, A.4
Buckner, M.5
Founk, K.6
Hu, Y.7
Sharifpoor, S.8
Rosebrock, A.P.9
Andrews, B.10
Winston, F.11
Perrimon, N.12
-
42
-
-
0344011603
-
Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses
-
Rubbi, C. P., and Milner, J. (2003) Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses. EMBO J. 22, 6068-6077
-
(2003)
EMBO J
, vol.22
, pp. 6068-6077
-
-
Rubbi, C.P.1
Milner, J.2
-
43
-
-
78149391411
-
A protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit export
-
Wild, T., Horvath, P., Wyler, E., Widmann, B., Badertscher, L., Zemp, I., Kozak, K., Csucs, G., Lund, E., and Kutay, U. (2010) A protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit export. PLos Biol. 8, e1000522
-
(2010)
PLos Biol.
, vol.8
-
-
Wild, T.1
Horvath, P.2
Wyler, E.3
Widmann, B.4
Badertscher, L.5
Zemp, I.6
Kozak, K.7
Csucs, G.8
Lund, E.9
Kutay, U.10
-
44
-
-
0037716643
-
Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway
-
Thomas, F., and Kutay, U. (2003) Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway. J. Cell Sci. 116, 2409-2419
-
(2003)
J. Cell Sci.
, vol.116
, pp. 2409-2419
-
-
Thomas, F.1
Kutay, U.2
-
45
-
-
79952293503
-
Activation of mTORC2 by association with the ribosome
-
Zinzalla, V., Stracka, D., Oppliger, W., and Hall, M. N. (2011) Activation of mTORC2 by association with the ribosome. Cell 144, 757-768
-
(2011)
Cell
, vol.144
, pp. 757-768
-
-
Zinzalla, V.1
Stracka, D.2
Oppliger, W.3
Hall, M.N.4
-
46
-
-
79960006439
-
BDNF-promoted increases in proximal dendrites occur via CREBdependent transcriptional regulation of cypin
-
Kwon, M., Fernández, J. R., Zegarek, G. F., Lo, S. B., and Firestein, B. L. (2011) BDNF-promoted increases in proximal dendrites occur via CREBdependent transcriptional regulation of cypin. J. Neurosci. 31, 9735-9745
-
(2011)
J. Neurosci
, vol.31
, pp. 9735-9745
-
-
Kwon, M.1
Fernández, J.R.2
Zegarek, G.F.3
Lo, S.B.4
Firestein, B.L.5
-
47
-
-
84878790595
-
A genome-wide screen of CREB occupancy identifies the RhoA inhibitors Par6C and Rnd3 as regulators of BDNF-induced synaptogenesis
-
Lesiak, A., Pelz, C., Ando, H., Zhu, M., Davare, M., Lambert, T. J., Hansen, K. F., Obrietan, K., Appleyard, S. M., Impey, S., and Wayman, G. A. (2013) A genome-wide screen of CREB occupancy identifies the RhoA inhibitors Par6C and Rnd3 as regulators of BDNF-induced synaptogenesis. PLoS ONE 8, e64658
-
(2013)
PLoS ONE
, vol.8
-
-
Lesiak, A.1
Pelz, C.2
Ando, H.3
Zhu, M.4
Davare, M.5
Lambert, T.J.6
Hansen, K.F.7
Obrietan, K.8
Appleyard, S.M.9
Impey, S.10
Wayman, G.A.11
-
48
-
-
0035923735
-
Neuronal RNA granules: A link between RNA localization and stimulation-dependent translation
-
Krichevsky, A. M., and Kosik, K. S. (2001) Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation. Neuron 32, 683-696
-
(2001)
Neuron
, vol.32
, pp. 683-696
-
-
Krichevsky, A.M.1
Kosik, K.S.2
-
49
-
-
39949085583
-
Stress granules: The Tao of RNA triage
-
Anderson, P., and Kedersha, N. (2008) Stress granules: the Tao of RNA triage. Trends Biochem. Sci. 33, 141-150
-
(2008)
Trends Biochem. Sci.
, vol.33
, pp. 141-150
-
-
Anderson, P.1
Kedersha, N.2
-
50
-
-
33749493493
-
Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2α phosphorylation
-
Mazroui, R., Sukarieh, R., Bordeleau, M. E., Kaufman, R. J., Northcote, P., Tanaka, J., Gallouzi, I., and Pelletier, J. (2006) Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2α phosphorylation. Mol. Biol. Cell 17, 4212-4219
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 4212-4219
-
-
Mazroui, R.1
Sukarieh, R.2
Bordeleau, M.E.3
Kaufman, R.J.4
Northcote, P.5
Tanaka, J.6
Gallouzi, I.7
Pelletier, J.8
-
51
-
-
66349136830
-
Uncoupling stress granule assembly and translation initiation inhibition
-
Mokas, S., Mills, J. R., Garreau, C., Fournier, M. J., Robert, F., Arya, P., Kaufman, R. J., Pelletier, J., and Mazroui, R. (2009) Uncoupling stress granule assembly and translation initiation inhibition. Mol. Biol. Cell 20, 2673-2683
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 2673-2683
-
-
Mokas, S.1
Mills, J.R.2
Garreau, C.3
Fournier, M.J.4
Robert, F.5
Arya, P.6
Kaufman, R.J.7
Pelletier, J.8
Mazroui, R.9
-
52
-
-
79958003442
-
Nucleolar disruption and apoptosis are distinct neuronal responses to etoposide-induced DNA damage
-
Pietrzak, M., Smith, S. C., Geralds, J. T., Hagg, T., Gomes, C., and Hetman, M. (2011) Nucleolar disruption and apoptosis are distinct neuronal responses to etoposide-induced DNA damage. J. Neurochem. 117, 1033-1046
-
(2011)
J. Neurochem.
, vol.117
, pp. 1033-1046
-
-
Pietrzak, M.1
Smith, S.C.2
Geralds, J.T.3
Hagg, T.4
Gomes, C.5
Hetman, M.6
-
54
-
-
0038579657
-
Gene profiling of hippocampal neuronal culture
-
Dabrowski, M., Aerts, S., Van Hummelen, P., Craessaerts, K., De Moor, B., Annaert, W., Moreau, Y., and De Strooper, B. (2003) Gene profiling of hippocampal neuronal culture. J. Neurochem. 85, 1279-1288
-
(2003)
J. Neurochem.
, vol.85
, pp. 1279-1288
-
-
Dabrowski, M.1
Aerts, S.2
Van Hummelen, P.3
Craessaerts, K.4
De Moor, B.5
Annaert, W.6
Moreau, Y.7
De Strooper, B.8
-
55
-
-
79959243863
-
Synapses on demand require dendrites at the ready: How defining stages of dendritic development in vitro could inform studies of behaviorally driven information storage in the brain
-
Withers, G. S., Wallace, C. S., Gibbs, E. M., Emery, I. R., and Applegate, M. L. (2011) Synapses on demand require dendrites at the ready: how defining stages of dendritic development in vitro could inform studies of behaviorally driven information storage in the brain. Dev. Psychobiol. 53, 443-455
-
(2011)
Dev. Psychobiol
, vol.53
, pp. 443-455
-
-
Withers, G.S.1
Wallace, C.S.2
Gibbs, E.M.3
Emery, I.R.4
Applegate, M.L.5
-
56
-
-
0018714818
-
Ribosomal RNA precursors in neuronal and glial rat brain nuclei
-
Stoykova, A. S., Dabeva, M. D., Dimova, R. N., and Hadjiolov, A. A. (1979) Ribosomal RNA precursors in neuronal and glial rat brain nuclei. J. Neurochem. 33, 931-937
-
(1979)
J. Neurochem.
, vol.33
, pp. 931-937
-
-
Stoykova, A.S.1
Dabeva, M.D.2
Dimova, R.N.3
Hadjiolov, A.A.4
-
57
-
-
0020601043
-
Different rates of synthesis and turnover of ribosomal RNA in rat brain and liver
-
Stoykova, A. S., Dudov, K. P., Dabeva, M. D., and Hadjiolov, A. A. (1983) Different rates of synthesis and turnover of ribosomal RNA in rat brain and liver. J. Neurochem. 41, 942-949
-
(1983)
J. Neurochem.
, vol.41
, pp. 942-949
-
-
Stoykova, A.S.1
Dudov, K.P.2
Dabeva, M.D.3
Hadjiolov, A.A.4
-
58
-
-
77956271728
-
Analysis of proteome dynamics in the mouse brain
-
Price, J. C., Guan, S., Burlingame, A., Prusiner, S. B., and Ghaemmaghami, S. (2010) Analysis of proteome dynamics in the mouse brain. Proc. Natl. Acad. Sci. U.S.A. 107, 14508-14513
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 14508-14513
-
-
Price, J.C.1
Guan, S.2
Burlingame, A.3
Prusiner, S.B.4
Ghaemmaghami, S.5
-
59
-
-
0014805853
-
Changes in polysomes of the developing rat brain
-
Yamagami, S., and Mori, K. (1970) Changes in polysomes of the developing rat brain. J. Neurochem. 17, 721-731
-
(1970)
J. Neurochem.
, vol.17
, pp. 721-731
-
-
Yamagami, S.1
Mori, K.2
-
60
-
-
0023902453
-
Protein turnover and growth of the rat brain from the foetus to old age
-
Goldspink, D. F. (1988) Protein turnover and growth of the rat brain from the foetus to old age. J. Neurochem. 50, 1364-1368
-
(1988)
J. Neurochem.
, vol.50
, pp. 1364-1368
-
-
Goldspink, D.F.1
-
61
-
-
30544442753
-
Regulation of dendritic morphogenesis by Ras-PI3K-Akt-mTOR and Ras-MAPK signaling pathways
-
Kumar, V., Zhang, M. X., Swank, M. W., Kunz, J., and Wu, G. Y. (2005) Regulation of dendritic morphogenesis by Ras-PI3K-Akt-mTOR and Ras-MAPK signaling pathways. J. Neurosci. 25, 11288-11299
-
(2005)
J. Neurosci
, vol.25
, pp. 11288-11299
-
-
Kumar, V.1
Zhang, M.X.2
Swank, M.W.3
Kunz, J.4
Wu, G.Y.5
-
62
-
-
84884215045
-
CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation
-
De Rubeis, S., Pasciuto, E., Li, K. W., Fernández, E., Di Marino, D., Buzzi, A., Ostroff, L. E., Klann, E., Zwartkruis, F. J., Komiyama, N. H., Grant, S. G., Poujol, C., Choquet, D., Achsel, T., Posthuma, D., Smit, A. B., and Bagni, C. (2013) CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation. Neuron 79, 1169-1182
-
(2013)
Neuron
, vol.79
, pp. 1169-1182
-
-
De Rubeis, S.1
Pasciuto, E.2
Li, K.W.3
Fernández, E.4
Di Marino, D.5
Buzzi, A.6
Ostroff, L.E.7
Klann, E.8
Zwartkruis, F.J.9
Komiyama, N.H.10
Grant, S.G.11
Poujol, C.12
Choquet, D.13
Achsel, T.14
Posthuma, D.15
Smit, A.B.16
Bagni, C.17
-
63
-
-
0027956623
-
Neurites can remain viable after destruction of the neuronal soma by programmed cell death (apoptosis)
-
Deckwerth, T. L., and Johnson, E. M., Jr. (1994) Neurites can remain viable after destruction of the neuronal soma by programmed cell death (apoptosis). Dev. Biol. 165, 63-72
-
(1994)
Dev. Biol.
, vol.165
, pp. 63-72
-
-
Deckwerth, T.L.1
Johnson, E.M.2
-
64
-
-
77957190328
-
+ ATPase subunit isoforms and leads to the degeneration of neuronal networks
-
+ ATPase subunit isoforms and leads to the degeneration of neuronal networks. J. Neurosci. 30, 12816-12830
-
(2010)
J. Neurosci
, vol.30
, pp. 12816-12830
-
-
Shiina, N.1
Yamaguchi, K.2
Tokunaga, M.3
-
65
-
-
84859954603
-
Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair
-
Jung, H., Yoon, B. C., and Holt, C. E. (2012) Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair. Nat. Rev. Neurosci. 13, 308-324
-
(2012)
Nat. Rev. Neurosci
, vol.13
, pp. 308-324
-
-
Jung, H.1
Yoon, B.C.2
Holt, C.E.3
-
66
-
-
70349847477
-
A reporter of local dendritic translocation shows plaque- related loss of neural system function in APP-transgenic mice
-
Meyer-Luehmann, M., Mielke, M., Spires-Jones, T. L., Stoothoff, W., Jones, P., Bacskai, B. J., and Hyman, B. T. (2009) A reporter of local dendritic translocation shows plaque- related loss of neural system function in APP-transgenic mice. J. Neurosci. 29, 12636-12640
-
(2009)
J. Neurosci
, vol.29
, pp. 12636-12640
-
-
Meyer-Luehmann, M.1
Mielke, M.2
Spires-Jones, T.L.3
Stoothoff, W.4
Jones, P.5
Bacskai, B.J.6
Hyman, B.T.7
-
67
-
-
84860863700
-
Cell-free formation of RNA granules: Bound RNAs identify features and components of cellular assemblies
-
Han, T. W., Kato, M., Xie, S., Wu, L. C., Mirzaei, H., Pei, J., Chen, M., Xie, Y., Allen, J., Xiao, G., and McKnight, S. L. (2012) Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies. Cell 149, 768-779
-
(2012)
Cell
, vol.149
, pp. 768-779
-
-
Han, T.W.1
Kato, M.2
Xie, S.3
Wu, L.C.4
Mirzaei, H.5
Pei, J.6
Chen, M.7
Xie, Y.8
Allen, J.9
Xiao, G.10
McKnight, S.L.11
-
68
-
-
84904021040
-
Altered translation of GATA1 in Diamond-Blackfan anemia
-
Ludwig, L. S., Gazda, H. T., Eng, J. C., Eichhorn, S. W., Thiru, P., Ghazvinian, R., George, T. I., Gotlib, J. R., Beggs, A. H., Sieff, C. A., Lodish, H. F., Lander, E. S., and Sankaran, V. G. (2014) Altered translation of GATA1 in Diamond-Blackfan anemia. Nat. Med. 20, 748-753
-
(2014)
Nat. Med.
, vol.20
, pp. 748-753
-
-
Ludwig, L.S.1
Gazda, H.T.2
Eng, J.C.3
Eichhorn, S.W.4
Thiru, P.5
Ghazvinian, R.6
George, T.I.7
Gotlib, J.R.8
Beggs, A.H.9
Sieff, C.A.10
Lodish, H.F.11
Lander, E.S.12
Sankaran, V.G.13
-
70
-
-
84885107449
-
Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons
-
Li, Y., Wang, H., Muffat, J., Cheng, A. W., Orlando, D. A., Lovén, J., Kwok, S. M., Feldman, D. A., Bateup, H. S., Gao, Q., Hockemeyer, D., Mitalipova, M., Lewis, C. A., Vander Heiden, M. G., Sur, M., Young, R. A., and Jaenisch, R. (2013) Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons. Cell Stem Cell 13, 446-458
-
(2013)
Cell Stem Cell
, vol.13
, pp. 446-458
-
-
Li, Y.1
Wang, H.2
Muffat, J.3
Cheng, A.W.4
Orlando, D.A.5
Lovén, J.6
Kwok, S.M.7
Feldman, D.A.8
Bateup, H.S.9
Gao, Q.10
Hockemeyer, D.11
Mitalipova, M.12
Lewis, C.A.13
Vander Heiden, M.G.14
Sur, M.15
Young, R.A.16
Jaenisch, R.17
-
71
-
-
84887292335
-
Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome
-
Xu, B., Lee, K. K., Zhang, L., and Gerton, J. L. (2013) Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet. 9, e1003857
-
(2013)
PLoS Genet.
, vol.9
-
-
Xu, B.1
Lee, K.K.2
Zhang, L.3
Gerton, J.L.4
-
72
-
-
84936114684
-
L-Leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome
-
Xu, B., Sowa, N., Cardenas, M. E., and Gerton, J. L. (2015) L-Leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome. Hum. Mol. Genet. 24, 1540-1555
-
(2015)
Hum. Mol. Genet.
, vol.24
, pp. 1540-1555
-
-
Xu, B.1
Sowa, N.2
Cardenas, M.E.3
Gerton, J.L.4
-
73
-
-
84883446343
-
Stress granules in neurodegeneration-lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma
-
Bentmann, E., Haass, C., and Dormann, D. (2013) Stress granules in neurodegeneration-lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma. FEBS J. 280, 4348-4370
-
(2013)
FEBS J
, vol.280
, pp. 4348-4370
-
-
Bentmann, E.1
Haass, C.2
Dormann, D.3
-
74
-
-
84892699468
-
Physiological protein aggregation run amuck: Stress granules and the genesis of neurodegenerative disease
-
Wolozin, B. (2014) Physiological protein aggregation run amuck: stress granules and the genesis of neurodegenerative disease. Discov. Med. 17, 47-52
-
(2014)
Discov. Med.
, vol.17
, pp. 47-52
-
-
Wolozin, B.1
|