Parkinson's disease DJ-1 l166p alters rrna biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Vilotti, Sandra ^a   Codrich, Marta ^a   dal Ferro, Marco ^b,c   Pinto, Milena ^a   Ferrer, Isidro ^d,e   Collavin, Licio ^b,c   Gustincich, Stefano ^a,d,e   Zucchelli, Silvia ^a,d,e  

^a SISSA   (Italy)

^b Laboratorio Nazionale Consorzio Interuniversitario Biotecnologie   (Italy)

^c UNIVERSITY OF TRIESTE   (Italy)

^d BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^e ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DJ 1 PROTEIN; LEUCINE; MUTANT PROTEIN; PROLINE; RECEPTOR PROTEIN; RIBOSOME RNA; TRAF AND TNF RECEPTOR ASSOCIATED PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; NUCLEAR PROTEIN; ONCOPROTEIN; PARK7 PROTEIN, HUMAN; PROTEASOME; SIGNAL PEPTIDE; TDP2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ARTICLE; BIOGENESIS; CELL AGGREGATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LEWY BODY; MOLECULAR PATHOLOGY; NEUROBLASTOMA CELL; NUCLEOLUS; PARKINSON DISEASE; PROTEIN FOLDING; PROTEIN LOCALIZATION; CELL FRACTIONATION; CELL PROLIFERATION; GENETICS; METABOLISM; SUBSTANTIA NIGRA; TUMOR CELL LINE;

CELL FRACTIONATION; CELL LINE, TUMOR; CELL NUCLEOLUS; CELL PROLIFERATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEWY BODIES; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PARKINSON DISEASE; PROTEASOME ENDOPEPTIDASE COMPLEX; RNA, RIBOSOMAL; SUBSTANTIA NIGRA; TNF RECEPTOR-ASSOCIATED FACTOR 6; TRANSCRIPTION FACTORS;

EID: 84859965734     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035051     Document Type: Article

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