Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis

Annals of the Rheumatic Diseases

Volumn 75, Issue 5, 2016, Pages 916-923

  Chen, Liye ^a   Ridley, Anna ^a   Hammitzsch, Ariane ^a   Al Mossawi, Mohammad Hussein ^a   Bunting, Helen ^a   Georgiadis, Dimitris ^b   Chan, Antoni ^c   Kollnberger, Simon ^a   Bowness, Paul ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF ATHENS   (Greece)

^c ROYAL BERKSHIRE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPEPTIDASE; ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1; HLA B27 ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 2; UNCLASSIFIED DRUG; ERAP1 PROTEIN, HUMAN; IMMUNOGLOBULIN HEAVY CHAIN; MINOR HISTOCOMPATIBILITY ANTIGEN;

ANKYLOSING SPONDYLITIS; ANTIGEN BINDING; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH17 CELL; ADULT; ANTAGONISTS AND INHIBITORS; ANTIGEN PRESENTING CELL; BIOSYNTHESIS; COCULTURE; FEMALE; GENE SILENCING; GENETICS; GENOTYPE; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; MONOCYTE; SEVERITY OF ILLNESS INDEX;

ADULT; AMINOPEPTIDASES; ANTIGEN-PRESENTING CELLS; CD4-POSITIVE T-LYMPHOCYTES; COCULTURE TECHNIQUES; FEMALE; GENE SILENCING; GENOTYPE; HLA-B27 ANTIGEN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; INTERLEUKIN-2; MALE; MIDDLE AGED; MINOR HISTOCOMPATIBILITY ANTIGENS; MONOCYTES; SEVERITY OF ILLNESS INDEX; SPONDYLITIS, ANKYLOSING; TH17 CELLS;

EID: 84963591436     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2014-206996     Document Type: Article

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