Neutrophil-derived chemokines on the road to immunity

Seminars in Immunology

Volumn 28, Issue 2, 2016, Pages 119-128

  Tecchio, Cristina ^a   Cassatella, Marco A ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

Adaptive immunity; Chemokines; Immune mediated diseases; Infections; Innate immunity; Neutrophils; Tumors

Indexed keywords

CHEMOKINE;

HUMAN; IMMUNE RESPONSE; IMMUNITY; IMMUNOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFECTION; NEOPLASM; NEUTROPHIL; NONHUMAN; OBSERVATIONAL STUDY; REVIEW; ADAPTIVE IMMUNITY; ANIMAL; CHEMOTAXIS; DISEASE PREDISPOSITION; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; LEUKOCYTE ACTIVATION; METABOLISM;

ADAPTIVE IMMUNITY; ANIMALS; CHEMOKINES; CHEMOTAXIS; DISEASE SUSCEPTIBILITY; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY; IMMUNITY, INNATE; NEUTROPHIL ACTIVATION; NEUTROPHILS;

EID: 84963565271     PISSN: 10445323     EISSN: 10963618     Source Type: Journal    
DOI: 10.1016/j.smim.2016.04.003     Document Type: Review

References (112)

1. Sokol C.L., Luster A.D. The chemokine system in innate immunity. Cold Spring Harbor Perspect. Biol. 2015, 7(January (5)). (pii: a016303).
2. Strieter R.M., Polverini P.J., Kunkel S.L., Arenberg D.A., Burdick M.D., Kasper J., Dzuiba J., Van Damme J., Walz A., Marriott D., et al. The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J. Biol. Chem. 1995, 270:27348-27357.
3. Oppenheim J.J., Zachariae C.O., Mukaida N., Matsushima K. Properties of the novel proinflammatory supergene intercrine cytokine family. Annu. Rev. Immunol. 1991, 9:617-648.
4. Baggiolini M., Dewald B., Moser B. Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines. Adv. Immunol. 1994, 55:97-179.
5. Farber J.M. Mig and IP-10: CXC chemokines that target lymphocytes. J. Leukoc. Biol. 1997, 61:246-257.
6. Cole K.E., Strick C.A., Paradis T.J., Ogborne K.T., Loetscher M., Gladue R.P., Lin W., Boyd J.G., Moser B., Wood D.E., Sahagan B.G., Neote K. Interferon-inducible T cell alpha chemoattractant (I-tAC): a novel non-eLR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J. Exp. Med. 1998, 187:2009-2021.
7. Rollins B.J. Chemokines. Blood 1997, 90:909-928.
8. Murphy P.M. International Union of Pharmacology: XXX. Update on chemokine receptor nomenclature. Pharmacol. Rev. 2002, 54:227-229.
9. Rossi D., Zlotnik A. The biology of chemokines and their receptors. Annu. Rev. Immunol. 2000, 18:217-242.
10. Zlotnik A., Yoshie O. The chemokine superfamily revisited. Immunity 2012, 36:705-716.
11. Mantovani A. Chemokines: introduction and overview. Chem. Immunol. 1999, 72:1-6.
12. Ward S.G., Bacon K., Westwick J. Chemokines and T lymphocytes: more than an attraction. Immunity 1998, 9:1-11.
13. Tecchio C., Cassatella M.A. Neutrophil-derived cytokines involved in physiological and pathological angiogenesis. Chem. Immunol. Allergy 2014, 99:123-137.
14. Tazzyman S., Niaz H., Murdoch C. Neutrophil-mediated tumour angiogenesis: subversion of immune responses to promote tumour growth. Semin. Cancer Biol. 2013, 23:149-158.
15. Chow M.T., Luster A.D. Chemokines in cancer. Cancer Immunol. Res. 2014, 2:1125-1131.
16. Scapini P., Lapinet-Vera J.A., Gasperini S., Calzetti F., Bazzoni F., Cassatella M.A. The neutrophil as a cellular source of chemokines. Immunol. Rev. 2000, 177:195-203.
17. Luster A.D. Chemokines-chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 1998, 338:436-445.
18. Hosking M.P., Lane T.E. The role of chemokines during viral infection of the CNS. PLoS Pathog. 2010, 6:e1000937.
19. Iannello A., Thompson T.W., Ardolino M., Lowe S.W., Raulet D.H. p53-Dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells. J. Exp. Med. 2013, 210:2057-2069.
20. Mócsai A. Diverse novel functions of neutrophils in immunity, inflammation, and beyond. J. Exp. Med. 2013, 210:1283-1299.
21. Scapini P., Cassatella M.A. Social networking of human neutrophils within the immune system. Blood 2014, 124:710-719.
22. Tecchio C., Micheletti A., Cassatella M.A. Neutrophil-derived cytokines: facts beyond expression. Front. Immunol. 2014, 5:508.
23. SadikC.D.Kim N.D., Luster A.D. Neutrophils cascading their way to inflammation. Trends Immunol. 2011, 32:452-460.
24. Cassatella M.A. The production of cytokines by polymorphonuclear neutrophils. Immunol. Today 1995, 16:21-26.
25. Blidberg K., Palmberg L., Dahlén B., Lantz A.S., Larsson K. Chemokine release by neutrophils in chronic obstructive pulmonary disease. Innate Immun. 2012, 18:503-510.
26. Schauer C., Janko C., Munoz L.E., Zhao Y., Kienhöfer D., Frey B., Lell M., Manger B., Rech J., Naschberger E., Holmdahl R., Krenn V., Harrer T., Jeremic I., Bilyy R., Schett G., Hoffmann M., Herrmann M. Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines. Nat. Med. 2014, 20:511-517.
27. Wittamer V., Bondue B., Guillabert A., Vassart G., Parmentier M., Communi D. Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity. J. Immunol. 2005, 175:487-493.
28. Kobayashi Y. The role of chemokines in neutrophil biology. Front. Biosci. 2008, 13:2400-2407.
29. Wright H.L., Moots R.J., Edwards S.W. The multifactorial role of neutrophils in rheumatoid arthritis. Nat Rev. Rheumatol. 2014, 10:593-601.
30. Cassatella M.A. Neutrophil-derived proteins: selling cytokines by the pound. Adv. Immunol. 1999, 73:369-509.
31. Suzuki S., Kobayashi M., Chiba K., Horiuchi I., Wang J., Kondoh T., Hashino S., Tanaka J., Hosokawa M., Asaka M. Autocrine production of epithelial cell-derived neutrophil attractant-78 induced by granulocyte colony-stimulating factor in neutrophils. Blood 2002, 99:1863-1865.
32. Nguyen-Jackson H.T., Li H.S., Zhang H., Ohashi E., Watowich S.S. G-CSF-activated STAT3 enhances production of the chemokine MIP-2 in bone marrow neutrophils. J. Leukoc. Biol. 2012, 92:1215-1225.
33. Jung Y.S., Lee H.Y., Kim S.D., Park J.S., Kim J.K., Suh P.G., Bae Y.S. Wnt5a stimulates chemotactic migration and chemokine production in human neutrophils. Exp. Mol. Med. 2013, 45:e27.
34. Riedel D.D., Kaufmann S.H. Chemokine secretion by human polymorphonuclear granulocytes after stimulation with Mycobacterium tuberculosis and lipoarabinomannan. Infect. Immun. 1997, 65:4620-4623.
35. Gasparoto T.H., de Oliveira C.E., Vieira N.A., Porto V.C., Cunha F.Q., Garlet G.P., Campanelli A.P., Lara V.S. Activation pattern of neutrophils from blood of elderly individuals with Candida-related denture stomatitis. Eur. J. Clin. Microbiol. Infect. Dis. 2012, 31:1271-1277.
36. Shimoyama T., Fukuda S., Liu Q., Nakaji S., Fukuda Y., Sugawara K. Helicobacter pylori water soluble surface proteins prime human neutrophils for enhanced production of reactive oxygen species and stimulate chemokine production. J. Clin. Pathol. 2003, 56:348-351.
37. Polenghi A., Bossi F., Fischetti F., Durigutto P., Cabrelle A., Tamassia N., Cassatella M.A., Montecucco C., Tedesco F., de Bernard M. The neutrophil-activating protein of Helicobacter pylori crosses endothelia to promote neutrophil adhesion in vivo. J. Immunol. 2007, 178:1312-1320.
38. Zurek O.W., Pallister K.B., Voyich J.M. Staphylococcus aureus inhibits neutrophil-derived IL-8 to promote cell death. J. Infect. Dis. 2015, 212:934-938.
39. Wright H.J., Chapple I.L., Matthews J.B., Cooper P.R. Fusobacterium nucleatum regulation of neutrophil transcription. J. Periodontal Res. 2011, 46:1-12.
40. Scapini P., Laudanna C., Pinardi C., Allavena P., Mantovani A., Sozzani S., Cassatella M.A. Neutrophils produce biologically active macrophage inflammatory protein-3alpha (MIP-3alpha)/CCL20 and MIP-3beta/CCL19. Eur. J. Immunol. 2001, 31:1981-1988.
41. Akahoshi T., Sasahara T., Namai R., Matsui T., Watabe H., Kitasato H., Inoue M., Kondo H. Production of macrophage inflammatory protein 3alpha (MIP-3alpha) (CCL20) and MIP-3beta (CCL19) by human peripheral blood neutrophils in response to microbial pathogens. Infect. Immun. 2003, 71:524-526.
42. Scapini P., Crepaldi L., Pinardi C., Calzetti F., Cassatella M.A. CCL20/macrophage inflammatory protein-3alpha production in LPS-stimulated neutrophils is enhanced by the chemoattractant formyl-methionyl-leucyl-phenylalanine and IFN-gamma through independent mechanisms. Eur. J. Immunol. 2002, 32:3515-3524.
43. Yoshimura T., Takahashi M. IFN-gamma-mediated survival enables human neutrophils to produce MCP-1/CCL2 in response to activation by TLR ligands. J. Immunol. 2007, 179:1942-1949.
44. Hilda J.N., Narasimhan M., Das S.D. Neutrophils from pulmonary tuberculosis patients show augmented levels of chemokines MIP-1α, IL-8 and MCP-1 which further increase upon in vitro infection with mycobacterial strains. Hum. Immunol. 2014, 75:914-922.
45. Suttmann H., Riemensberger J., Bentien G., Schmaltz D., Stöckle M., Jocham D., Böhle A., Brandau S. Neutrophil granulocytes are required for effective Bacillus Calmette-Guérin immunotherapy of bladder cancer and orchestrate local immune responses. Cancer Res. 2006, 66:8250-8257.
46. Chuah C., Jones M.K., Burke M.L., McManus D.P., Owen H.C., Gobert G.N. Defining a pro-inflammatory neutrophil phenotype in response to schistosome eggs. Cell. Microbiol. 2014, 16:1666-1677.
47. Chuah C., Jones M.K., Burke M.L., Owen H.C., Anthony B.J., McManus D.P., Ramm G.A., Gobert G.N. Spatial and temporal transcriptomics of Schistosoma japonicum-induced hepatic granuloma formation reveals novel roles for neutrophils. J. Leukoc. Biol. 2013, 94:353-365.
48. Gasperini S., Marchi M., Calzetti F., Laudanna C., Vicentini L., Olsen H., Murphy M., Liao F., Farber J., Cassatella M.A. Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils. J. Immunol. 1999, 162:4928-4937.
49. Tamassia N., Calzetti F., Ear T., Cloutier A., Gasperini S., Bazzoni F., McDonald P.P., Cassatella M.A. Molecular mechanisms underlying the synergistic induction of CXCL10 by LPS and IFN-gamma in human neutrophils. Eur. J. Immunol. 2007, 37:2627-2634.
50. Jaillon S., Galdiero M.R., Del Prete D., Cassatella M.A., Garlanda C., Mantovani A. Neutrophils in innate and adaptive immunity. Semin. Immunopathol. 2013, 35:377-394.
51. Del Prete G., Maggi E., Romagnani S. Human Th1 and Th2 cells: functional properties, mechanisms of regulation, and role in disease. Lab. Invest. 1994, 70:299-306.
52. Bussmeyer U., Sarkar A., Broszat K., Lüdemann T., Möller S., van Zandbergen G., Bogdan C., Behnen M., Dumler J.S., von Loewenich F.D., Solbach W., Laskay T. Impairment of gamma interferon signaling in human neutrophils infected with Anaplasma phagocytophilum. Infect. Immun. 2010, 78:358-363.
53. Jauregui C.E., Wang Q., Wright C.J., Takeuchi H., Uriarte S.M., Lamont R.J. Suppression of T-cell chemokines by Porphyromonas gingivalis. Infect. Immun. 2013, 81:2288-2295.
54. Pelletier M., Maggi L., Micheletti A., Lazzeri E., Tamassia N., Costantini C., Cosmi L., Lunardi C., Annunziato F., Romagnani S., Cassatella M.A. Evidence for a cross-talk between human neutrophils and Th17 cells. Blood 2010, 115:335-343.
55. Annunziato F., Romagnani C., Romagnani S. The 3 major types of innate and adaptive cell-mediated effector immunity. J. Allergy Clin. Immunol. 2015, 135:626-635.
56. Burkett P.R., Meyer zu Horste G., Kuchroo V.K. Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity. J. Clin. Invest. 2015, 125:2211-2219.
57. Codolo G., Bossi F., Durigutto P., Bella C.D., Fischetti F., Amedei A., Tedesco F., D'Elios S., Cimmino M., Micheletti A., Cassatella M.A., D'Elios M.M., de Bernard M. Orchestration of inflammation and adaptive immunity in Borrelia burgdorferi-induced arthritis by neutrophil-activating protein A. Arthritis Rheum. 2013, 65:1232-1242.
58. Benelli R., Barbero A., Ferrini S., Scapini P., Cassatella M., Bussolino F., Tacchetti C., Noonan D.M., Albini A. Human immunodeficiency virus transactivator protein (Tat) stimulates chemotaxis, calcium mobilization, and activation of human polymorphonuclear leukocytes: implications for Tat-mediated pathogenesis. J. Infect. Dis. 2000, 182:1643-1651.
59. König B., Krusat T., Streckert H.J., König W. IL-8 release from human neutrophils by the respiratory syncytial virus is independent of viral replication. J. Leukoc. Biol. 1996, 60:253-260.
60. Jaovisidha P., Peeples M.E., Brees A.A., Carpenter L.R., Moy J.N. Respiratory syncytial virus stimulates neutrophil degranulation and chemokine release. J. Immunol. 1999, 163:2816-2820.
61. Tang F.S., Van Ly D., Spann K., Reading P.C., Burgess J.K., Hartl D., Baines K.J., Oliver B.G. Differential neutrophil activation in viral infections: enhanced TLR-7/8-mediated CXCL8 release in asthma. Respirology 2016, 21:172-179.
62. Molesworth-Kenyon S.J., Milam A., Rockette A., Troupe A., Oakes J.E., Lausch R.N. Expression, inducers and cellular sources of the chemokine MIG (CXCL 9), during primary herpes simplex virus type-1 infection of the cornea. Curr. Eye Res. 2015, 40:800-808.
63. Kibiki G.S., Myers L.C., Kalambo C.F., Hoang S.B., Stoler M.H., Stroup S.E., Houpt E.R. Bronchoalveolar neutrophils, interferon gamma-inducible protein 10 and interleukin-7 in AIDS-associated tuberculosis. Clin. Exp. Immunol. 2007, 148:254-259.
64. Yoshida T., Kobayashi M., Li X.D., Pollard R.B., Suzuki F. Inhibitory effect of glycyrrhizin on the neutrophil-dependent increase of R5HIV replication in cultures of macrophages. Immunol. Cell Biol. 2009, 87:554-558.
65. Tamassia N., Zimmermann M., Castellucci M., Ostuni R., Bruderek K., Schilling B., Brandau S., Bazzoni F., Natoli G., Cassatella M.A. Cutting edge: an inactive chromatin configuration at the IL-10 locus in human neutrophils. J. Immunol. 2013, 190:1921-1925.
66. Bezerra C.A., Cardoso T.M., Giudice A., Porto A.F., Santos S.B., Carvalho E.M., Bacellar O. Evaluation of the microbicidal activity and cytokines/chemokines profile released by neutrophils from HTLV-1-infected individuals. Scand. J. Immunol. 2011, 74:310-317.
67. Tamassia N., Le Moigne V., Rossato M., Donini M., McCartney S., Calzetti F., Colonna M., Bazzoni F., Cassatella M.A. Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils. J. Immunol. 2008, 181:6563-6573.
68. Zimmermann M., Aguilera F.B., Castellucci M., Rossato M., Costa S., Lunardi C., Ostuni R., Girolomoni G., Natoli G., Bazzoni F., Tamassia N., Cassatella M.A. Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils. Nat. Commun. 2015, 6:6061.
69. Dorhoi A., Iannacone M., Farinacci M., Faé K.C., Schreiber J., Moura-Alves P., Nouailles G., Mollenkopf H.J., Oberbeck-Müller D., Jörg S., Heinemann E., Hahnke K., Löwe D., Del Nonno F., Goletti D., Capparelli R., Kaufmann S.H. MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment. J. Clin. Invest. 2013, 123:4836-4848.
70. Charmoy M., Brunner-Agten S., Aebischer D., Auderset F., Launois P., Milon G., Proudfoot A.E., Tacchini-Cottier F. Neutrophil-derived CCL3 is essential for the rapid recruitment of dendritic cells to the site of Leishmania major inoculation in resistant mice. PLoS Pathog. 2010, 6:e1000755.
71. León B., López-Bravo M., Ardavín C. Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania. Immunity 2007, 26:519-531.
72. Bennouna S., Bliss S.K., Curiel T.J., Denkers E.Y. Cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection. J. Immunol. 2003, 171:6052-6058.
73. von Stebut E., Metz M., Milon G., Knop J., Maurer M. Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1alpha/beta released from neutrophils recruited by mast cell-derived TNFalpha. Blood 2003, 101:210-215.
74. Tsuda Y., Takahashi H., Kobayashi M., Hanafusa T., Herndon D.N., Suzuki F. Three different neutrophil subsets exhibited in mice with different susceptibilities to infection by methicillin-resistant Staphylococcus aureus. Immunity 2004, 21:215-226.
75. Takahashi H., Tsuda Y., Kobayashi M., Herndon D.N., Suzuki F. CCL2 as a trigger of manifestations of compensatory anti-inflammatory response syndrome in mice with severe systemic inflammatory response syndrome. J. Leukoc. Biol. 2006, 79:789-796.
76. Ioannidis L.J., Nie C.Q., Ly A., Ryg-Cornejo V., Chiu C.Y., Hansen D.S. Monocyte- and neutrophil-derived CXCL10 impairs efficient control of blood-stage malaria infection and promotes severe disease. J. Immunol. 2016, 196:1227-1238.
77. Ichikawa A., Kuba K., Morita M., Chida S., Tezuka H., Hara H., Sasaki T., Ohteki T., Ranieri V.M., dos Santos C.C., Kawaoka Y., Akira S., Luster A.D., Lu B., Penninger J.M., Uhlig S., Slutsky A.S., Imai Y. CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin. Am. J. Respir. Crit. Care Med. 2013, 187:65-77.
78. + T cells in the airways. Science 2015, 349(6252):aaa4352.
79. Haick A.K., Rzepka J.P., Brandon E., Balemba O.B., Miura T.A. Neutrophils are needed for an effective immune response against pulmonary rat coronavirus infection, but also contribute to pathology. J. Gen. Virol. 2014, 95(Pt 3):578-590.
80. Fridlender Z.G., Albelda S.M. Tumor-associated neutrophils: friend or foe. Carcinogenesis 2012, 33:949-955.
81. Tecchio C., Scapini P., Pizzolo G., Cassatella M.A. On the cytokines produced by human neutrophils in tumors. Semin. Cancer Biol. 2013, 23:159-170.
82. Zhu Q., Zhang X., Zhang L., Li W., Wu H., Yuan X., Mao F., Wang M., Zhu W., Qian H., Xu W. The IL-6-STAT3 axis mediates a reciprocal crosstalk between cancer-derived mesenchymal stem cells and neutrophils to synergistically prompt gastric cancer progression. Cell Death Dis. 2014, 19(5):e1295.
83. Peng H.H., Liang S., Henderson A.J., Dong C. Regulation of interleukin-8 expression in melanoma stimulated neutrophil inflammatory response. Exp. Cell Res. 2007, 313:551-559.
84. Hor W.S., Huang W.L., Lin Y.S., Yang B.C. Cross-talk between tumor cells and neutrophils through the Fas (APO-1, CD95)/FasL system: human glioma cells enhance cell viability and stimulate cytokine production in neutrophils. J. Leukoc. Biol. 2003, 73:363-368.
85. Dumitru C.A., Fechner M.K., Hoffmann T.K., Lang S., Brandau S. A novel p38-MAPK signaling axis modulates neutrophil biology in head and neck cancer. J. Leukoc. Biol. 2012, 91:591-598.
86. Yuan A., Chen J.J., Yao P.L., Yang P.C. The role of interleukin-8 in cancer cells and microenvironment interaction. Front. Biosci. 2005, 10:853-865.
87. Trellakis S., Bruderek K., Dumitru C.A., Gholaman H., Gu X., Bankfalvi A., Scherag A., Hütte J., Dominas N., Lehnerdt G.F., Hoffmann T.K., Lang S., Brandau S. Polymorphonuclear granulocytes in human head and neck cancer: enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease. Int. J. Cancer 2011, 129:2183-2193.
88. Chiba K., Zhao W., Chen J., Wang J., Cui H.Y., Kawakami H., Miseki T., Satoshi H., Tanaka J., Asaka M., Kobayashi M. Neutrophils secrete MIP-1 beta after adhesion to laminin contained in basement membrane of blood vessels. Br. J. Haematol. 2004, 127:592-597.
89. Tsuda Y., Fukui H., Asai A., Fukunishi S., Miyaji K., Fujiwara S., Teramura K., Fukuda A., Higuchi K. An immunosuppressive subtype of neutrophils identified in patients with hepatocellular carcinoma. J. Clin. Biochem. Nutr. 2012, 51:204-212.
90. Zhou S.L., Zhou Z.J., Hu Z.Q., Huang X.W., Wang Z., Chen E.B., Fan J., Cao Y., Dai Z., Zhou J. Tumor-associated neutrophils recruit macrophages and T-regulatory cells to promote progression of hepatocellular carcinoma and resistance to sorafenib. Gastroenterology 2016, 16(February):231-236. pii: S0016-5085 (Epub ahead of print). 10.1053/j.gastro.2016.02.040.
91. Mishalian I., Bayuh R., Eruslanov E., Michaeli J., Levy L., Zolotarov L., Singhal S., Albelda S.M., Granot Z., Fridlender Z.G. Neutrophils recruit regulatory T-cells into tumors via secretion of CCL17-a new mechanism of impaired antitumor immunity. Int. J. Cancer 2014, 135:1178-1186.
92. Eruslanov E.B., Bhojnagarwala P.S., Quatromoni J.G., Stephen T.L., Ranganathan A., Deshpande C., Akimova T., Vachani A., Litzky L., Hancock W.W., Conejo-Garcia J.R., Feldman M., Albelda S.M., Singhal S. Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer. J. Clin. Invest. 2014, 124:5466-5480.
93. Zhang Y., Patel B., Dey A., Ghorani E., Rai L., Elham M., Castleton A.Z., Fielding A.K. Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function. J. Immunol. 2012, 188:1002-1010.
94. Grote D., Cattaneo R., Fielding A.K. Neutrophils contribute to the measles virus-induced antitumor effect: enhancement by granulocyte macrophage colony-stimulating factor expression. Cancer Res. 2003, 63:6463-6468.
95. Fridlender Z.G., Sun J., Mishalian I., Singhal S., Cheng G., Kapoor V., Horng W., Fridlender G., Bayuh R., Worthen G.S., Albelda S.M. Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils. PLoS One 2012, 7(2):e31524.
96. Fridlender Z.G., Sun J., Kim S., Kapoor V., Cheng G., Ling L., Worthen G.S., Albelda S.M. Polarization of tumor-associated neutrophil phenotype by TGF-beta: N1 versus N2 TAN. Cancer Cell 2009, 16:183-194.
97. Sionov R.V., Fridlender Z.G., Granot Z. The multifaceted roles neutrophils play in the tumor microenvironment. Cancer Microenviron. 2015, 8:125-158.
98. Ma X., Aoki T., Tsuruyama T., Narumiya S. Definition of prostaglandin E2-EP2 signals in the colon tumor microenvironment that amplify inflammation and tumor growth. Cancer Res. 2015, 75:2822-2832.
99. Immune mediated diseases: from theory to therapy. Advances in Experimental Medicine and Biology 2007, Springer. M.R. Shurin, Y.S. Smolkin (Eds.).
100. Wright H.L., Moots R.J., Edwards S.W. The multifactorial role of neutrophils in rheumatoid arthritis. Nat. Rev. Rheumatol. 2014, 10:593-601.
101. Gagné V., Marois L., Levesque J.M., Galarneau H., Lahoud M.H., Caminschi I., Naccache P.H., Tessier P., Fernandes M.J. Modulation of monosodium urate crystal-induced responses in neutrophils by the myeloid inhibitory C-type lectin-like receptor: potential therapeutic implications. Arthritis Res. Ther. 2013, 15:R73.
102. Schett G., Schauer C., Hoffmann M., Herrmann M. Why does the gout attack stop? A roadmap for the immune pathogenesis of gout. RMD Open 2015, 1(Suppl 1):e000046.
103. Auer J., Bläss M., Schulze-Koops H., Russwurm S., Nagel T., Kalden J.R., Röllinghoff M., Beuscher H.U. Expression and regulation of CCL18 in synovial fluid neutrophils of patients with rheumatoid arthritis. Arthritis Res. Ther. 2007, 9(5):R94.
104. Schlenk J., Lorenz H.M., Haas J.P., Herrmann M., Hohenberger G., Kalden J.R., Röllinghoff M., Beuscher H.U. Extravasation into synovial tissue induces CCL20 mRNA expression in polymorphonuclear neutrophils of patients with rheumatoid arthritis. J. Rheumatol. 2005, 32:2291-2298.
105. Egesten A., Eliasson M., Olin A.I., Erjefält J.S., Bjartell A., Sangfelt P., Carlson M. The proinflammatory CXC-chemokines GRO-alpha/CXCL1 and MIG/CXCL9 are concomitantly expressed in ulcerative colitis and decrease during treatment with topical corticosteroids. Int. J. Colorectal Dis. 2007, 22:1421-1427.
106. Gladigau G., Haselmayer P., Scharrer I., Munder M., Prinz N., Lackner K., Schild H., Stein P., Radsak M.P. A role for toll-like receptor mediated signals in neutrophils in the pathogenesis of the anti-phospholipid syndrome. PLoS One 2012, 7:e42176.
107. Kondo Y., Kobayashi K., Asabe S., Shiina M., Niitsuma H., Ueno Y., Kobayashi T., Shimosegawa T. Vigorous response of cytotoxic T lymphocytes associated with systemic activation of CD8T lymphocytes in fulminant hepatitis B. Liver Int. 2004, 24:561-567.
108. Takai S., Kimura K., Nagaki M., Satake S., Kakimi K., Moriwaki H. Blockade of neutrophil elastase attenuates severe liver injury in hepatitis B transgenic mice. J. Virol. 2005, 79:15142-15150.
109. Molesworth-Kenyon S.J., Oakes J.E., Lausch R.N. A novel role for neutrophils as a source of T cell-recruiting chemokines IP-10 and Mig during the DTH response to HSV-1 antigen. J. Leukoc. Biol. 2005, 77:552-559.
110. Li J.L., Lim C.H., Tay F.W., Goh C.C., Devi S., Malleret B., Lee B., Bakocevic N., Chong S.Z., Evrard M., Tanizaki H., Lim H.Y., Russell B., Renia L., Zolezzi F., Poidinger M., Angeli V., St John A.L., Harris J.E., Tey H.L., Tan S.M., Kabashima K., Weninger W., Larbi A., Ng L.G. Neutrophils self-regulate immune complex-mediated cutaneous inflammation through CXCL2. J. Invest. Dermatol. 2016, 136:416-424.
111. Chertov O., Yang D., Howard O.M., Oppenheim J.J. Leukocyte granule proteins mobilize innate host defenses and adaptive immune responses. Immunol. Rev. 2000, 177:68-78.
112. Cloutier A., Guindi C., Larivée P., Dubois C.M., Amrani A., McDonald P.P. Inflammatory cytokine production by human neutrophils involves C/EBP transcription factors. J. Immunol. 2009, 182:563-571.