The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity

Science

Volumn 352, Issue 6281, 2016, Pages 99-103

  Chan, Pamela Y ^a   Carrera Silva, Eugenio A ^a,b   De Kouchkovsky, Dimitri ^a   Joannas, Leonel D ^a   Hao, Liming ^a   Hu, Donglei ^c   Huntsman, Scott ^c   Eng, Celeste ^c   Licona Limón, Paula ^a,h   Weinstein, Jason S ^a   Herbert, De'Broski R ^d   Craft, Joseph E ^a   Flavell, Richard A ^a   Repetto, Silvia ^e,f   Correale, Jorge ^g   Burchard, Esteban G ^c,d   Torgerson, Dara G ^c   Ghosh, Sourav ^a   Rothlin, Carla V ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ACADEMIA NACIONAL DE MEDICINA   (Argentina)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^f HOSPITAL DE CLÍNICAS JOSÉ DE SAN MARTÍN   (Argentina)

^g Instituto de Investigaciones Neurologicas Raul Carrera   (Argentina)

^h UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 7; MACROPHAGE DERIVED CHEMOKINE; OX40 LIGAND; PROGRAMMED DEATH 1 LIGAND 2; PROTEIN TYROSINE KINASE; RANTES; REGULATOR PROTEIN; STAT6 PROTEIN; T CELL SPECIFIC PROS1; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TRANSFORMING GROWTH FACTOR BETA; TYROSINE KINASE TYRO3; UNCLASSIFIED DRUG; PLASMA PROTEIN; PROS1 PROTEIN, HUMAN; TYRO3 PROTEIN, HUMAN; TYRO3 PROTEIN, MOUSE;

ALLERGY; CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; IMMUNITY; METAZOAN; NEUTRALIZATION; PROTEIN; RODENT;

ADAPTIVE IMMUNITY; ADOPTIVE TRANSFER; ALLERGIC AIRWAY INFLAMMATION; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHOALVEOLAR LAVAGE FLUID; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELLULAR IMMUNITY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DERMATOPHAGOIDES; EFFECTOR CELL; HELMINTHIASIS; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOREGULATION; INNATE IMMUNITY; MEMORY T LYMPHOCYTE; MOUSE; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PARASITE CLEARANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE; ANIMAL; ANTAGONISTS AND INHIBITORS; ASTHMA; C57BL MOUSE; DISEASE MODEL; GENE INACTIVATION; GENETICS; HOST PARASITE INTERACTION; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; NIPPOSTRONGYLUS; PHYSIOLOGY; PYROGLYPHIDAE; STRONGYLE INFECTION;

METAZOA; MUS;

ADAPTIVE IMMUNITY; ANIMALS; ASTHMA; BLOOD PROTEINS; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; GENE KNOCKOUT TECHNIQUES; HOST-PARASITE INTERACTIONS; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-4; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NIPPOSTRONGYLUS; PYROGLYPHIDAE; RECEPTOR PROTEIN-TYROSINE KINASES; STRONGYLIDA INFECTIONS; T-LYMPHOCYTES;

EID: 84963553914     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaf1358     Document Type: Article

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