High-titer biosynthesis of hyaluronic acid by recombinant Corynebacterium glutamicum

Biotechnology Journal

Volumn 11, Issue 4, 2016, Pages 574-584

  Cheng, Fangyu ^a   Gong, Qianying ^b   Yu, Huimin ^a   Stephanopoulos, Gregory ^c  

^a TSINGHUA UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^c Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Corynebacterium glutamicum; Hyaluronic acid biosynthesis; Inducible promoter; Operon organization; Synthetic pathway

Indexed keywords

BATCH CELL CULTURE; BIOCHEMISTRY; BIOSYNTHESIS; CARBON; CLONING; GENE ENCODING; GENES; ORGANIC ACIDS;

BIOSYNTHETIC PATHWAY; CARBON AND NITROGEN; CELL WALL SYNTHESIS; CORYNEBACTERIUM GLUTAMICUM; ENVIRONMENTAL CONDITIONS; INDUCIBLE PROMOTER; RECOMBINANT STRAINS; SYNTHETIC PATHWAYS;

HYALURONIC ACID;

CARBON; CORN SYRUP; ENDOTOXIN; EXOTOXIN; GLUCOSE; HYALURONIC ACID; NITROGEN; SYNTHETASE;

ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIUM CULTURE; BIOENGINEERING; BIOREACTOR; BIOSYNTHESIS; CLONE; CODON; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; GENETIC CODE; NONHUMAN; OPERON; POWDER; PRIORITY JOURNAL; PROMOTER REGION; BATCH CELL CULTURE; CHEMISTRY; FERMENTATION; GENETIC ENGINEERING; GENETICS; GROWTH, DEVELOPMENT AND AGING;

BATCH CELL CULTURE TECHNIQUES; CORYNEBACTERIUM GLUTAMICUM; FERMENTATION; GENETIC ENGINEERING; GLUCOSE; HIGH FRUCTOSE CORN SYRUP; HYALURONIC ACID; OPERON;

EID: 84963502701     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201500404     Document Type: Article

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