Rationale and design of the allogeneiC human mesenchymal stem cells (hMSC) in patients with aging fRAilTy via intravenoUS delivery (CRATUS) study: A phase I/II, randomized, blinded and placebo controlled trial to evaluate the Safety and potential efficacy of allogeneic human mesenchymal stem cell infusion in patients with aging frailty

Oncotarget

Volumn 7, Issue 11, 2016, Pages 11899-11912

  Golpanian, Samuel ^a   DiFede, Darcy L ^a   Pujol, Marietsy V ^a   Lowery, Maureen H ^a   Levis Dusseau, Silvina ^a   Goldstein, Bradley J ^a   Schulman, Ivonne H ^a   Longsomboon, Bangon ^a   Wolf, Ariel ^a   Khan, Aisha ^a   Heldman, Alan W ^a   Goldschmidt Clermont, Pascal J ^a   Hare, Joshua M ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Allogeneic; Frailty; Gerotarget; Mesenchymal stem cells

Indexed keywords

AGING; ALLOGENEIC STEM CELL TRANSPLANTATION; ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DONOR SELECTION; DOUBLE BLIND PROCEDURE; FRAILTY; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; PATIENT SAFETY; PHYSICAL DISEASE; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; STUDY DESIGN; AGED; ALLOTRANSPLANTATION; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CYTOLOGY; FEMALE; FOLLOW UP; FRAIL ELDERLY; IMMUNOLOGY; INFLAMMATION; INNATE IMMUNITY; INTRAVENOUS DRUG ADMINISTRATION; MALE; MESENCHYMAL STROMA CELL; METHODOLOGY; MIDDLE AGED; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PHYSIOLOGY; PROGNOSIS; REGENERATIVE MEDICINE; SURVIVAL RATE; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AGING; CARDIOVASCULAR DISEASES; FEMALE; FOLLOW-UP STUDIES; FRAIL ELDERLY; HUMANS; IMMUNITY, INNATE; INFLAMMATION; INFUSIONS, INTRAVENOUS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; PROGNOSIS; REGENERATIVE MEDICINE; RESEARCH DESIGN; SURVIVAL RATE; TRANSPLANTATION, HOMOLOGOUS;

EID: 84962911758     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.7727     Document Type: Article

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