Alterations in coagulation following major liver resection

Anaesthesia

Volumn 71, Issue 6, 2016, Pages 657-668

  Mallett, S V ^a   Sugavanam, A ^b   Krzanicki, D A ^a   Patel, S ^c   Broomhead, R H ^d   Davidson, B R ^e   Riddell, A ^a   Gatt, A ^f   Chowdary, P ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

^b Worthing Hospital   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^d KING S COLLEGE HOSPITAL   (United Kingdom)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF MALTA   (Malta)

Author keywords

coagulation factors; elevated INR; hepatic resection

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8; PROTEIN C; PROTHROMBIN; VON WILLEBRAND FACTOR; BLOOD CLOTTING FACTOR; THROMBIN;

ADULT; ARTICLE; BLOOD CLOTTING; FEMALE; HUMAN; INTERNATIONAL NORMALIZED RATIO; LIVER RESECTION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; POSTOPERATIVE PERIOD; PROSPECTIVE STUDY; THROMBOCYTE COUNT; AGED; BIOSYNTHESIS; MIDDLE AGED;

AGED; BLOOD COAGULATION; BLOOD COAGULATION FACTORS; FEMALE; HEPATECTOMY; HUMANS; INTERNATIONAL NORMALIZED RATIO; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PROTEIN C; THROMBIN;

EID: 84962900064     PISSN: 00032409     EISSN: 13652044     Source Type: Journal    
DOI: 10.1111/anae.13459     Document Type: Article

References (45)

1. Walia A,. Anesthetic management for liver resection. Journal of Gastrointestinal Surgery 2006; 10: 168-9.
2. Stamenkovic DM, Jankovic ZB, Toogood GJ, Lodge JP, Bellamy MC,. Epidural analgesia and liver resection: postoperative coagulation disorders and epidural catheter removal. Minerva Anestesiologica 2011; 77: 671-9.
3. Russell MC,. Complications following hepatectomy. Surgical Oncology Clinics of North America 2015; 24: 73-96.
4. Lim C, Dokmak S, Farges O, Aussilhou B, Sauvanet A, Belghiti J,. Reoperation for post-hepatectomy hemorrhage: increased risk of mortality. Langenbeck's Archives of Surgery 2014; 399: 735-40.
5. Yamazaki S, Takayama T, Kimura Y, et al., Transfusion criteria for fresh frozen plasma in liver resection: a 3 + 3 cohort expansion study. Archives of Surgery 2011; 146: 1293-9.
6. Elterman KG, Xiong Z,. Coagulation profile changes and safety of epidural analgesia after hepatectomy: a retrospective study. Journal of Anesthesia 2015; 29: 367-72.
7. Stanworth SJ, Grant-Casey J, Lowe D, et al., The use of fresh-frozen plasma in England: high levels of inappropriate use in adults and children. Transfusion 2011; 51: 62-70.
8. Shah A, Stanworth SJ, McKechnie S,. Evidence and triggers for the transfusion of blood and blood products. Anaesthesia 2015; 70 (Suppl 1): 10-9, e3-5.
9. Weiss MJ, Kim Y, Ejaz A, et al., Venous thromboembolic prophylaxis after a hepatic resection: patterns of care among liver surgeons. Joutnal of the Hepato-Pancreato-Biliary Association 2014; 16: 892-8.
10. Tzeng CW, Katz MH, Fleming JB, et al., Risk of venous thromboembolism outweighs post-hepatectomy bleeding complications: analysis of 5651 National Surgical Quality Improvement Program patients. Journal of the Hepato-Pancreato-Biliary Association 2012; 14: 506-13.
11. Melloul E, Dondero F, Vilgrain V, Raptis DA, Paugam-Burtz C, Belghiti J,. Pulmonary embolism after elective liver resection: a prospective analysis of risk factors. Journal of Hepatology 2012; 57: 1268-75.
12. Turley RS, Reddy SK, Shortell CK, Clary BM, Scarborough JE,. Venous thromboembolism after hepatic resection: analysis of 5,706 patients. Journal of Gastrointestinal Surgery 2012; 16: 1705-14.
13. Mukherjee D, Lidor AO, Chu KM, Gearhart SL, Haut ER, Chang DC,. Postoperative venous thromboembolism rates vary significantly after different types of major abdominal operations. Journal of Gastrointestinal Surgery 2008; 12: 2015-22.
14. Dondero F, Farges O, Belghiti J, et al., A prospective analysis of living-liver donation shows a high rate of adverse events. Journal of Hepato-Biliary-Pancreatic Surgery 2006; 13: 117-22.
15. Lo CM,. Complications and long-term outcome of living liver donors: a survey of 1,508 cases in five Asian centers. Transplantation 2003; 75 (Suppl 3): S12-15.
16. Ejaz A, Spolverato G, Kim Y, et al., Defining incidence and risk factors of venous thromboemolism after hepatectomy. Journal of Gastrointestinal Surgery 2014; 18: 1116-24.
17. De Martino RR, Goodney PP, Spangler EL, et al., Variation in thromboembolic complications among patients undergoing commonly performed cancer operations. Journal of Vascular Surgery 2012; 55: e4.
18. Tripodi A, Mannucci PM,. The coagulopathy of chronic liver disease. New England Journal of Medicine 2011; 365: 147-56.
19. Tripodi A, Caldwell SH, Hoffman M, Trotter JF, Sanyal AJ,. The prothrombin time test as a measure of bleeding risk and prognosis in liver disease. Alimentary Pharmacology and Therapeutics 2007; 26: 141-8.
20. Louis SG, Barton JS, Riha GM, et al., The international normalized ratio overestimates coagulopathy in patients after major hepatectomy. American Journal of Surgery 2014; 207: 723-7.
21. Potze W, Alkozai EM, Adelmeijer J, Porte RJ, Lisman T,. Hypercoagulability following major partial liver resection-detected by thrombomodulin-modified thrombin generation testing. Alimentary Pharmacology and Therapeutics 2015; 41: 189-98.
22. De Pietri L, Montalti R, Begliomini B, et al., Thromboelastographic changes in liver and pancreatic cancer surgery: hypercoagulability, hypocoagulability or normocoagulability? European Journal of Anaesthesiology 2010; 27: 608-16.
23. Weinberg L, Scurrah N, Parker EC, et al., Markers of coagulation activation after hepatic resection for cancer: evidence of sustained upregulation of coagulation. Anaesthesia and Intensive Care 2011; 39: 847-53.
24. Cerutti E, Stratta C, Romagnoli R, et al., Thromboelastogram monitoring in the perioperative period of hepatectomy for adult living liver donation. Liver Transplantation 2004; 10: 289-94.
25. Arshad F, Lisman T, Porte RJ,. Hypercoagulability as a contributor to thrombotic complications in the liver transplant recipient. Liver International 2013; 33: 820-7.
26. Tripodi A, Primignani M, Chantarangkul V, et al., An imbalance of pro- vs anti-coagulation factors in plasma from patients with cirrhosis. Gastroenterology 2009; 137: 2105-11.
27. Hemker HC, Giesen P, Al Dieri R, et al., Calibrated automated thrombin generation measurement in clotting plasma. Pathophysiology of Haemostasis and Thrombosis 2003; 33: 4-15.
28. Gatt A, van Veen JJ, Cooper P, Kitchen S, Makris M,. Protein C deficiency screening using a thrombin generation assay-an upgrade. Thrombosis and Haemostasis 2007; 98: 691-2.
29. Matot I, Scheinin O, Eid A, Jurim O,. Epidural anesthesia and analgesia in liver resection. Anesthesia and Analgesia 2002; 95: 1179-81.
30. Lison S, Weiss G, Spannagl M, Heindl B,. Postoperative changes in procoagulant factors after major surgery. Blood Coagulation and Fibrinolysis 2011; 22: 190-6.
31. Barton JS, Riha GM, Differding JA, et al., Coagulopathy after a liver resection: is it over diagnosed and over treated? Journal of the Hepato-Pancreato-Biliary Association 2013; 15: 865-71.
32. Krzanicki D, Sugavanam A, Mallett S,. Intraoperative hypercoagulability during liver transplantation as demonstrated by thromboelastography. Liver Transplantation 2013; 19: 852-61.
33. Muller MC, Meijers JC, Vroom MB, Juffermans NP,. Utility of thromboelastography and/or thromboelastometry in adults with sepsis: a systematic review. Critical Care 2014; 18: R30.
34. Stravitz RT,. Potential applications of thromboelastography in patients with acute and chronic liver disease. Gastroenterology and Hepatology 2012; 8: 513-20.
35. Herbstreit F, Winter EM, Peters J, Hartmann M,. Monitoring of haemostasis in liver transplantation: comparison of laboratory based and point of care tests. Anaesthesia 2010; 65: 44-9.
36. Haas T, Spielmann N, Mauch J, et al., Comparison of thromboelastometry (ROTEM) with standard plasmatic coagulation testing in paediatric surgery. British Journal of Anaesthesia 2012; 108: 36-41.
37. Gorlinger K, Saner FH,. Prophylactic plasma and platelet transfusion in the critically Ill patient: just useless and expensive or even harmful? BMC Anesthesiology 2015; 15: 86.
38. Golder M, Mewburn J, Lillicrap D,. In vitro and in vivo evaluation of the effect of elevated factor VIII on the thrombogenic process. Thrombosis and Haemostasis 2013; 109: 53-60.
39. Theusinger OM, Schroder CM, Eismon J, et al., The influence of laboratory coagulation tests and clotting factor levels on Rotation Thromboelastometry (ROTEM) during major surgery with hemorrhage. Anesthesia and Analgesia 2013; 117: 314-21.
40. Gordon N, Riha G, Billingsley K, Schreiber M,. Malignancy does not dictate the hypercoagulable state following liver resection. American Journal of Surgery 2015; 209: 870-4.
41. Mallett SV, Armstrong M,. Point-of-care monitoring of haemostasis. Anaesthesia 2015; 70 (Suppl 1): 73-7, e25-6.
42. Lambing A, Kuriakose P, Abouljoud MS,. Hypercoagulability risks among adult living liver donors. Transplantation Proceedings 2006; 38: 3579-81.
43. Peyvandi F, Palla R, Menegatti M, et al., Coagulation factor activity and clinical bleeding severity in rare bleeding disorders: results from the European Network of Rare Bleeding Disorders. Journal of Thrombosis and Haemostasis 2012; 10: 615-21.
44. Schofield N, Sugavanam A, Henley M, Thompson K, Riddell A, Mallett SV,. An in vitro study comparing two dose regimes of fresh frozen plasma on conventional and thromboelastographic tests of coagulation after major hepatic resection. Transfusion Medicine 2015; 25: 85-91.
45. Reddy SK, Turley RS, Barbas AS, et al., Post-operative pharmacologic thromboprophylaxis after major hepatectomy: does peripheral venous thromboembolism prevention outweigh bleeding risks? Journal of Gastrointestinal Surgery 2011; 15: 1602-10.