Dihydro-Resveratrol Ameliorates Lung Injury in Rats with Cerulein-Induced Acute Pancreatitis

Phytotherapy Research

Volumn 30, Issue 4, 2016, Pages 663-670

  Lin, Ze Si ^a,b   Ku, Chuen Fai ^a   Guan, Yi Fu ^a   Xiao, Hai Tao ^a   Shi, Xiao Ke ^a   Wang, Hong Qi ^b   Bian, Zhao Xiang ^a   Tsang, Siu Wai ^a   Zhang, Hong Jie ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

acute pancreatitis; acute pancreatitis associated lung injury; cerulein; dihydro resveratrol; pro inflammatory cytokines; trans resveratrol

Indexed keywords

AMYLASE; CERULETIDE; DIHYDRO RESVERATROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MYELOPEROXIDASE; RESVERATROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; PEROXIDASE; STILBENE DERIVATIVE;

ACUTE PANCREATITIS; ALVEOLAR THICKENING; AMYLASE BLOOD LEVEL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG STRUCTURE; ENZYME ACTIVITY; INTRACELLULAR SIGNALING; LUNG DISEASE; LUNG EDEMA; LUNG HEMORRHAGE; LUNG INJURY; NONHUMAN; OUTCOME ASSESSMENT; RAT; ANIMAL; BLOOD; CHEMICALLY INDUCED; COMPLICATION; DRUG EFFECTS; LUNG; LUNG DISEASES; METABOLISM; PANCREAS; PANCREATITIS; PATHOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ALPHA-AMYLASES; ANIMALS; CERULETIDE; CYTOKINES; LUNG; LUNG DISEASES; NF-KAPPA B; PANCREAS; PANCREATITIS; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STILBENES;

EID: 84962892101     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5576     Document Type: Article

References (35)

1. Bhatia M, Brady M, Zagorski J, et al., 2000. Treatment with neutralising antibody against cytokine induced neutrophil chemoattractant (CINC) protects rats against acute pancreatitis associated lung injury. Gut 47: 838-844.
2. Bhatia M, Neoptolemos JP, Slavin J,. 2001. Inflammatory mediators as therapeutic targets in acute pancreatitis. Curr Opin Investig Drugs 2 (4): 496-501.
3. Bian ZX, Tsang SW,. 2014. Therapeutic implications of antioxidant defense in acute pancreatitis. Hepatobiliary Pancreat Dis Int 13 (4): 346-347.
4. Bonizzi G, Karin M,. 2004. The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol 25 (6): 280-288.
5. Chao KC, Chao KF, Chuang CC, Liu SH,. 2006. Blockade of interleukin 6 accelerates acinar cell apoptosis and attenuates experimental acute pancreatitis in vivo. Br J Surg 93 (3): 332-338.
6. Charbonney E, Nathens AB,. 2008. Severe acute pancreatitis: a review. Surg Infect (Larchmt) 9 (6): 573-578.
7. El-Feraly FS,. 1984. Isolation, characterization, and synthesis of 3,5,4′-trihydrozybibenzyl from Cannabis sativa. J Nat Prod 47: 89-92.
8. Farris P, Krutmann J, Li YH, McDaniel D, Krol Y,. 2013. Resveratrol: a unique antioxidant offering a multi-mechanistic approach for treating aging skin. J Drugs Dermatol 12 (12): 1389-1394.
9. Fritzemeier KH, Kindl H,. 1983. 9,10-Dihydrophenanthrenes as phytoalexins of Orchidaceae. Biosynthetic studies in vitro and in vivo proving the route from L-phenylalanine to dihydro-m-coumaric acid, dihydrostilbene and dihydrophenanthrenes. Eur J Biochem 133 (3): 545-550.
10. Fujimoto K, Hosotani R, Doi R, et al., 1997. Role of neutrophils in cerulein-induced pancreatitis in rats: possible involvement of apoptosis. Digestion 58 (5): 421-430.
11. Huai JP, Sun XC, Chen MJ, et al., 2012. Melatonin attenuates acute pancreatitis-associated lung injury in rats by modulating interleukin 22. World J Gastroenterol 18 (36): 5122-5128.
12. Jiang CY, Wang W, Tang JX, Yuan ZR,. 2013. The adipocytokine resistin stimulates the production of proinflammatory cytokines TNF-alpha and IL-6 in pancreatic acinar cells via NF-kappaB activation. J Endocrinol Invest 36 (11): 986-992.
13. Kitada M, Koya D,. 2013. Renal protective effects of resveratrol. Oxid Med Cell Longev 2013: 568093.
14. Li N, Wu X, Holzer RG, et al., 2013. Loss of acinar cell IKKalpha triggers spontaneous pancreatitis in mice. J Clin Invest 123 (5): 2231-2243.
15. Luan ZG, Zhang J, Yin XH, Ma XC, Guo RX,. 2013. Ethyl pyruvate significantly inhibits tumour necrosis factor-alpha, interleukin-1beta and high mobility group box 1 releasing and attenuates sodium taurocholate-induced severe acute pancreatitis associated with acute lung injury. Clin Exp Immunol 172 (3): 417-426.
16. McFadden DW,. 1991. Organ failure and multiple organ system failure in pancreatitis. Pancreas 6 (Suppl 1): S37-S43.
17. Milani Junior R, Pereira PM, Dolhnikoff M, Saldiva PH, Martins MA,. 1995. Respiratory mechanics and lung morphometry in severe pancreatitis-associated acute lung injury in rats. Crit Care Med 23 (11): 1882-1889.
18. Pervaiz S, Holme AL,. 2009. Resveratrol: its biologic targets and functional activity. Antioxid RedoxSignal 11 (11): 2851-2897.
19. Rakonczay Z Jr, Hegyi P, Takacs T, McCarroll J, Saluja AK,. 2008. The role of NF-kappaB activation in the pathogenesis of acute pancreatitis. Gut 57 (2): 259-267.
20. Renner IG, Savage WT 3rd, Pantoja JL, Renner VJ,. 1985. Death due to acute pancreatitis. A retrospective analysis of 405 autopsy cases. Dig Dis Sci 30 (10): 1005-1018.
21. Satoh A, Shimosegawa T, Fujita M, et al., 1999. Inhibition of nuclear factor-kappaB activation improves the survival of rats with taurocholate pancreatitis. Gut 44 (2): 253-258.
22. Steinberg W, Tenner S,. 1994. Acute pancreatitis. N Engl J Med 330 (17): 1198-1210.
23. Tong LX, Young LC,. 2014. Nutrition: the future of melanoma prevention? J Am Acad Dermatol 71 (1): 151-160.
24. Tsang SW, Ip SP, Wong TP, Che CT, Leung PS,. 2003. Differential effects of saralasin and ramiprilat, the inhibitors of renin-angiotensin system, on cerulein-induced acute pancreatitis. Regul Pept 111 (1-3): 47-53.
25. Tsang SW, Ip SP, Leung PS,. 2004. Prophylactic and therapeutic treatments with AT 1 and AT 2 receptor antagonists and their effects on changes in the severity of pancreatitis. Int J Biochem Cell Biol 36 (2): 330-339.
26. Tsang SW, Zhang H, Lin C, et al., 2013. Rhein, a natural anthraquinone derivative, attenuates the activation of pancreatic stellate cells and ameliorates pancreatic fibrosis in mice with experimental chronic pancreatitis. PLoS One 8 (12): e82201.
27. Tsang SW, Bian ZX,. 2015. Anti-fibrotic and anti-tumorigenic effects of rhein, a natural anthraquinone derivative, in mammalian stellate and carcinoma cells. Phytother Res 29 (3): 407-414.
28. Tsang SW, Zhang HJ, Chen YG, Auyeung KK, Bian ZX,. 2015a. Eruberin A, a natural flavanol glycoside, exerts anti-fibrotic action on pancreatic stellate cells. Cell Physiol Biochem 36 (6): 2433-2446.
29. Tsang SW, Zhang H, Lin Z, Mu H, Bian ZX,. 2015b. Anti-fibrotic effect of trans-resveratrol on pancreatic stellate cells. Biomed Pharmacother 71: 91-97.
30. Tsang SW, Ip SP, Wu JC, Ng SC, Yung KK, Bian ZX,. 2015c. A Chinese medicinal formulation ameliorates dextran sulfate sodium-induced experimental colitis by suppressing the activity of nuclear factor-kappaB signlaing. J Ethnopharmacol 162: 20-30.
31. Xiong J, Ni J, Hu G, et al., 2013. Shikonin ameliorates cerulein-induced acute pancreatitis in mice. J Ethnopharmacol 145 (2): 573-580.
32. Walle T, Hsieh F, DeLegge MH, Oatis JE Jr, Walle UK,. 2004. High absorption but very low bioavailability of oral resveratrol in humans. Drug Metab Dispos 32 (12): 1377-1382.
33. Wang YZ, Zhang YC, Cheng JS, et al., 2014. BML-111, a lipoxin receptor agonist, ameliorates 'two-hit'-induced acute pancreatitis-associated lung injury in mice by the upregulation of heme oxygenase-1. Artif Cells Nanomed Biotechnol 42 (2): 110-120.
34. Weng TI, Wu HY, Chen BL, Liu SH,. 2012. Honokiol attenuates the severity of acute pancreatitis and associated lung injury via acceleration of acinar cell apoptosis. Shock 37 (5): 478-484.
35. Zhang H, Neuhofer P, Song L, et al., 2013. IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality. J Clin Invest 123 (3): 1019-1031.